PaulChristopherMcGovernMD

PubMed

• 3 citations
  Efficacy of Omadacycline Versus Moxifloxacin in the Treatment of Community-Acquired Bacterial Pneumonia by Disease Severity: Results From the OPTIC Study.
  Julio Ramirez, Daniel Deck, Paul B. Eckburg, Marla Curran, Anita Das, Courtney Kirsch, Amy Manley, Evan Tzanis, Paul C. McGovern> ;Open Forum Infectious Diseases. 2021 Jun 1
• 4 citations
  Clinical Efficacy of Patients With Secondary Bacteremia Treated With Omadacycline: Results From Phase 3 Acute Bacterial Skin and Skin Structure Infections and Communit...
  George Sakoulas, Paul B. Eckburg, Maria Amodio-Groton, Amy Manley, Evan Tzanis, Anita Das, Robert C. Noble, Paul C. McGovern> ;Open Forum Infectious Diseases. 2021 Jun 1
• 2 citations
  Safety and efficacy of omadacycline for treatment of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections in patients with mil...
  Oliver A. Cornely, Thomas M. File, Lynne Garrity-Ryan, Surya Chitra, Robert C. Noble, Paul C. McGovern> ;International Journal of Antimicrobial Agents. 2021 Feb 1
• 6 citations
  Omadacycline vs moxifloxacin in adults with community-acquired bacterial pneumonia.
  Antoni Torres, Lynne Garrity-Ryan, Courtney Kirsch, Judith N. Steenbergen, Paul B. Eckburg, Anita Das, Marla Curran, Amy Manley, Evan Tzanis, Paul C. McGovern> ;International Journal of Infectious Diseases. 2021 Jan 20
• 8 citations
  Safety and efficacy of omadacycline by BMI categories and diabetes history in two Phase III randomized studies of patients with acute bacterial skin and skin structure...
  Manjunath P. Pai, Mark H. Wilcox, Surya Chitra, Paul C. McGovern> ;The Journal of Antimicrobial Chemotherapy. 2021 Apr 13
• 6 citations
  The Effect of Verapamil, a P-gp Inhibitor, on the Pharmacokinetics, Safety, and Tolerability of Omadacycline in Healthy Adults: A Phase I, Open-Label, Single-Sequence ...
  Thomas L Hunt, Evan Tzanis, Stephen Bai, Amy Manley, Surya Chitra, Paul C. McGovern> ;European Journal of Drug Metabolism and Pharmacokinetics. 2021 Jan 1
• 56 citations
  Once-daily oral omadacycline versus twice-daily oral linezolid for acute bacterial skin and skin structure infections (OASIS-2): a phase 3, double-blind, multicentre, ...
  William O'Riordan, Carrie Cardenas, Elliot Shin, Alissa Sirbu, Lynne Garrity-Ryan, Anita Das, Paul B. Eckburg, Amy Manley, Judith N. Steenbergen, Evan Tzanis, Paul C. ...> ;The Lancet. Infectious Diseases. 2019 Oct 1
• 22 citations
  An Integrated Safety Summary of Omadacycline, a Novel Aminomethylcycline Antibiotic.
  Steven M. Opal, Thomas M. File, Tom van der Poll, Evan Tzanis, Surya Chitra, Paul C. McGovern> ;Clinical Infectious Diseases. 2019 Aug 1
• 11 citations
  Early Clinical Response in Community-acquired Bacterial Pneumonia: From Clinical Endpoint to Clinical Practice.
  Julio A. Ramirez, Evan Tzanis, Marla Curran, Robert C. Noble, Surya Chitra, Amy Manley, Courtney Kirsch, Paul C. McGovern> ;Clinical Infectious Diseases. 2019 Aug 1
• 23 citations
  Omadacycline for Acute Bacterial Skin and Skin Structure Infections.
  Fredrick M. Abrahamian, George Sakoulas, Evan Tzanis, Amy Manley, Judith N. Steenbergen, Anita Das, Paul B. Eckburg, Paul C. McGovern> ;Clinical Infectious Diseases. 2019 Aug 1
• 126 citations
  Omadacycline for Community-Acquired Bacterial Pneumonia
  Roman Stets, Monica Popescu, Joven Gonong, Ismail Mitha, William Nseir, Andrzej Madej, Courtney Kirsch, Anita Das, Lynne Garrity-Ryan, Judith N. Steenbergen, Amy Manle...> ;The New England Journal of Medicine. 2019 Feb 6
• In vitro activity of tigecycline against molecularly characterised strains of Enterobacteriaceae isolated from phase 3 clinical trials and the Tigecycline Evaluation a...
  Douglas J. Biedenbach, Meredith Hackel, Alvaro Quintana, Michele Wible, Michael J. Dowzicky, Paul C. McGovern, Samuel K. Bouchillon> ;Journal of Global Antimicrobial Resistance. 2015 Dec 1
• 15 citations
  Clinical response and mortality in tigecycline complicated intra-abdominal infection and complicated skin and soft-tissue infection trials.
  Matteo Bassetti, Paul C. McGovern, Christoph Wenisch, R. Daniel Meyer, Jean Li Yan, Michele Wible, Scott T. Rottinghaus, Alvaro Quintana> ;International Journal of Antimicrobial Agents. 2015 Sep 1
• 7 citations
  Methicillin-resistant Staphylococcus aureus infection epidemiology and clinical response from tigecycline soft tissue infection trials.
  Laura A Puzniak, Alvaro Quintana, Michele Wible, Tim Babinchak, Paul C. McGovern> ;Diagnostic Microbiology and Infectious Disease. 2014 Jun 1
• 14 citations
  Pancreatitis in tigecycline Phase 3 and 4 clinical studies
  Paul C. McGovern, Michele Wible, Joan M. Korth-Bradley, Alvaro Quintana> ;The Journal of Antimicrobial Chemotherapy. 2014 Mar 1
• 100 citations
  Distribution of 13-Valent Pneumococcal Conjugate Vaccine Streptococcus pneumoniae Serotypes in US Adults Aged ≥50 Years With Community-Acquired Pneumonia
  Robert Sherwin, Sharon Gray, Ronika Alexander, Paul C. McGovern, Jay Graepel, Michael W. Pride, Jay Purdy, Peter Paradiso, Thomas M. File> ;The Journal of Infectious Diseases. 2013 Dec 1
• 63 citations
  All-cause mortality imbalance in the tigecycline phase 3 and 4 clinical trials
  Paul C. McGovern, Michele Wible, Ahmed El-Tahtawy, Pinaki Biswas, R. Daniel Meyer> ;International Journal of Antimicrobial Agents. 2013 May 1
• 167 citations
  Randomized Phase 2 Trial To Evaluate the Clinical Efficacy of Two High-Dosage Tigecycline Regimens versus Imipenem-Cilastatin for Treatment of Hospital-Acquired Pneumonia
  Julio A. Ramirez, Nathalie Dartois, Hassan Gandjini, Jean Li Yan, Joan M. Korth-Bradley, Paul C. McGovern> ;Antimicrobial Agents and Chemotherapy. 2013 Apr 1
• 5 citations
  Tigecycline Does Not Prolong Corrected QT Intervals in Healthy Subjects
  Joan M. Korth-Bradley, Paul C. McGovern, Joanne Salageanu, Kyle Matschke, Anna Plotka, Sylvester Pawlak> ;Antimicrobial Agents and Chemotherapy. 2013 Apr 1
• Patient-Level Data Provide Additional Insight for Tigecycline All-Cause Mortality Meta-analysis
  Paul C. McGovern, Alvaro Quintana> ;Clinical Infectious Diseases. 2012 Dec 15
• 23 citations
  A randomized trial of tigecycline versus ampicillin-sulbactam or amoxicillin-clavulanate for the treatment of complicated skin and skin structure infections
  Peter Matthews, Marc Alpert, Galia Rahav, Denise Rill, Edward T. Zito, David Gardiner, Ron Pedersen, Timothy Babinchak, Paul C. McGovern, Peter Armstrong, Charles L. B...> ;BMC Infectious Diseases. 2012 Nov 12
• 27 citations
  Efficacy of tigecycline versus ceftriaxone plus metronidazole for the treatment of complicated intra-abdominal infections: results from a randomized, controlled trial
  Niels Qvist, Brian Warren, Heidi Leister-Tebbe, Edward T Zito, Ronald Pedersen, Paul C. McGovern, Tim Babinchak> ;Surgical Infections. 2012 Apr 3
• 1 citations
  Clarification to the Systematic Review and Meta-Analysis Involving Tigecycline
  Paul C. McGovern, Timothy Babinchak, Alvaro Quintana> ;Antimicrobial Agents and Chemotherapy. 2011 Oct 1
• Consequences of the quality improvement revolution.
  Paul C. Mcgovern> ;JAMA. 2006 Nov 22
• 8 citations
  Legionella maceachernii pneumonia in a patient with HIV infection
  Kimberly L Dumoff, Paul C. McGovern, Paul H. Edelstein, Irving Nachamkin> ;Diagnostic Microbiology and Infectious Disease. 2004 Oct 1
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