Dr. Nghiem is on Doximity
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Office
825 Eastlake Ave E
Seattle, WA 98109Phone+1 855-557-0555Fax+1 206-606-1025- Is this information wrong?
Education & Training
- Massachusetts General Hospital/Beth Israel Deaconess Medical Center/Brigham and Women's HospResidency, Dermatology, 1995 - 1998
- Brigham and Women's HospitalResidency, Internal Medicine, 1994 - 1995
- Stanford University School of MedicineClass of 1994
- Stanford UniversityPh.D., Program in Cancer Biology, 1994
- Harvard UniversityA.B., Biological Sciences, 1986
Certifications & Licensure
- FL State Medical License 2021 - Present
- CA State Medical License 2022 - 2024
- WA State Medical License 2005 - 2024
- MA State Medical License 1998 - 2006
- American Board of Dermatology Dermatology
Clinical Trials
- Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial Start of enrollment: 2024 Sep 13
Roles: Contact, Principal Investigator
Publications & Presentations
PubMed
- Human Motor Neurons Elicit Pathological Hallmarks of ALS and Reveal Potential Biomarkers of the Disease in Response to Prolonged IFNγ Exposure.Changho Chun, Jung Hyun Lee, Mark Bothwell, Paul Nghiem, Alec S T Smith, David L Mack> ;The Journal of Neuroscience. 2024 Apr 17
- 1 citationsCirculating cancer-specific CD8 T cell frequency is associated with response to PD-1 blockade in Merkel cell carcinoma.Thomas Pulliam, Saumya Jani, Lichen Jing, Heeju Ryu, Ana Jojic, Carolyn Shasha, Jiajia Zhang, Rima Kulikauskas, Candice Church, Charlie Garnett-Benson, Ted Gooley, Aud...> ;Cell Reports. Medicine. 2024 Feb 20
- 1 citationsPostoperative Radiation Therapy Is Indicated for "Low-Risk" Pathologic Stage I Merkel Cell Carcinoma of the Head and Neck Region but Not for Other Locations.Bierma, M., Hippe, D., Lachance, K., Goff, P., Schaub, S., Wallner, K., Tseng, Y., Liao, J., Apisarnthanarax, S., Nghiem, P., Parvathaneni, U.> ;Advances in Radiation Oncology. 2024 Feb 1
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Journal Articles
- (P33) Case Report: Neutron Radiation Therapy for Refractory Merkel Cell Carcinoma in an Immunotherapy Primed Patient Potentiates the Immune ResponseSchaub SK, Stewart RD, Sandison GA, Arbuckle T, Liao JJ, Laramore GE, Zeng J, Rengan R, Tseng YD, Mayr NA, Bhatia S, Nghiem P, Parvathaneni U, International Journal of Radiation Oncology, Biology, Physics, 1/1/2018
- Case Report: Neutron Radiation Therapy for Refractory Merkel Cell Carcinoma in an Immunotherapy Primed Patient Potentiates the Immune ResponseSchaub SK, Stewart RD, Sandison GA, Arbuckle T, Liao JJ, Laramore GE, Zeng J, Rengan R, Tseng YD, Mayr NA, Bhatia S, Nghiem P, Parvathaneni U, International Journal of Radiation Oncology, Biology, Physics, 1/1/2018
- ResponseBhatia S, Storer BE, Nghiem P, J Natl Cancer Inst, 1/1/2017
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Books/Book Chapters
Abstracts/Posters
- Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet.Lu YP, Lou YR, Bernard JJ, Peng QY, Li T, Lin Y, Shih WJ, Nghiem P, Shapses S, Wagner GC, Conney AH, Proc Natl Acad Sci U S A, 1/1/2012
- Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators.Huryn D, Brodsky J, Brummond K, Chambers P, Eyre B, Ireland A, Kawasumi M, LaPorte M, Lloyd K, Manteau B, Nghiem P, Quade B, Wipf P, Proc Natl Acad Sci USA, 1/1/2011
- Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase.Kawasumi M, Lemos B, Bradner JE, Thibodeau R, Kim YS, Schmidt M, Higgins E, Koo SW, Angle-Zahn A, Chen A, Levine D, Nguyen L, Heffernan TP, Longo I, Mandinova A, Lu YP..., Proc Natl Acad Sci USA, 1/1/2011
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Lectures
- Late-breaking Research: Basic Science/Cutaneous Oncology/PathologyAmerican Academy of Dermatology - Annual Meeting 2019 - Washington, D.C. - 3/2/2019
- Seattle Investigative Dermatology, MCC & the immunogenic principles transforming the care of all UV-induced skin cancers.Oregon Convention Center, Portland, OR - 1/29/2017
- MCC & the immunogenic principles transforming the care of all UV-induced skin cancers, Clinical scholars program session II: Emerging immunotherapiesOregon Convention Center, Portland, OR - 1/29/2017
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Other
- Cancer: The Final Frontier.Nghiem P, Atlantic Monthly
1/25/2016 - "Cancer: The Final Frontier."Nghiem P, The Atlantic Monthly
1/25/2016 - Pembrolizumab yielded durable responses in patients with advanced Merkel cell carcinoma. (Interview)Nghiem P, AACR, ecancer.tv
1/19/2016 - Join now to see all
Press Mentions
- Leadership Succession: Sunrise, SunsetMay 17th, 2023
- Another Win for a JAK Inhibitor in Alopecia AreataMarch 19th, 2023
- Rare Skin Cancer Patients Face 40 Pc Recurrence Rate: StudyApril 30th, 2022
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Grant Support
- The Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2005–2012
- Humoral And Cellular Immunity In Polyomavirus-Linked Merkel Cell CarcinomaNational Cancer Institute2011
- Pathogenetic And Prognostic Studies For Improved Therapy Of Merkel Cell CarcinomaNational Cancer Institute2009–2011
- Targeting Mcpyv To Overcome Immune Evasion In Merkel Cell CarcinomaNational Cancer Institute2009–2010
- The Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2005–2008
- The Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2004–2005
- The Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2004
- Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2003
- Pik Related Kinases In The Response To DNA Damage By UVNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2002–2003
- Pik Related Kinases In The Response To DNA Damage By UVNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1999–2002
- Pik Related Kinases In The Response To DNA Damage By UVNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1998
Professional Memberships
- Fellow
Hospital Affiliations
- Fred Hutchinson Cancer CenterSeattle, Washington
- UW Medicine/University of Washington Medical CenterSeattle, Washington
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