PaulAgostinoRandazzoMDPhD

PubMed

• 10 citations
  Rigosertib induces mitotic arrest and apoptosis in RAS-driven rhabdomyosarcoma and neuroblastoma
  Joshua Kowalczyk, Xiaolin Wan, Edjay R. Hernandez, Ruibai Luo, Gaelyn C. Lyons, Kelli M. Wilson, Devorah C. Gallardo, Kristine A. Isanogle, Christina Robinson, Arnulfo...> ;Molecular Cancer Therapeutics. 2021 Feb 1
• 12 citations
  Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization.
  Chunguang Ren, Qianying Yuan, Xiaoying Jian, Paul A. Randazzo, Wenwen Tang, Dianqing Wu> ;Journal of Immunology. 2020 Feb 15
• 14 citations
  The ArfGAP ASAP1 Controls Actin Stress Fiber Organization via Its N-BAR Domain
  Anjelika Gasilina, Teresa Vitali, Ruibai Luo, Xiaoying Jian, Paul A. Randazzo> ;Iscience. 2019 Dec 20
• 9 citations
  Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate
  Neeladri Sekhar Roy, Xiaoying Jian, Olivier Soubias, Peng Zhai, Jessica R. Hall, Jessica N. Dagher, Nathan P. Coussens, Lisa M. Miller Jenkins, Ruibai Luo, Itoro Akpan...> ;The Journal of Biological Chemistry. 2019 Nov 15
• 135 citations
  ARF GTPases and their GEFs and GAPs: concepts and challenges
  Elizabeth Sztul, Pei Wen Chen, James E. Casanova, Jacqueline Cherfils, Joel B. Dacks, David G. Lambright, Fang-Jen S. Lee, Paul A. Randazzo, Lorraine C. Santy, Annette...> ;Molecular Biology of the Cell. 2019 May 15
• 10 citations
  Functional Expression and Characterization of Human Myristoylated-Arf1 in Nanodisc Membrane Mimetics
  Yifei Li, Olivier Soubias, Jess Li, Shangjin Sun, Paul A. Randazzo, R. Andrew Byrd> ;Biochemistry. 2019 Feb 8
• 9 citations
  The tuberous sclerosis complex subunit TBC1D7 is stabilized by Akt phosphorylation–mediated 14-3-3 binding
  James P. Madigan, Feng Hou, Linlei Ye, Jicheng Hu, Aiping Dong, Wolfram Tempel, Marielle E. Yohe, Paul A. Randazzo, Lisa M. Miller Jenkins, Michael M. Gottesman, Yufen...> ;The Journal of Biological Chemistry. 2018 Oct 19
• 7 citations
  ARAP2 inhibits Akt independently of its effects on focal adhesions.
  Ruibai Luo, Pei Wen Chen, Jean Cheng Kuo, Lisa M. Miller Jenkins, Xiaoying Jian, Clare M. Waterman, Paul A. Randazzo> ;Biology of the Cell. 2018 Dec 1
• 11 citations
  Arf GAPs and molecular motors
  Ruibai Luo, Christine E Reed, Jeffrey A Sload, Linda Wordeman, Paul A. Randazzo, Pei-Wen Chen> ;Small Gtpases. 2019 May 1
• 28 citations
  Arf GAPs: A family of proteins with disparate functions that converge on a common structure, the integrin adhesion complex.
  Teresa Vitali, Sofia Girald-Berlingeri, Paul A. Randazzo, Pei-Wen Chen> ;Small Gtpases. 2017 Mar 31
• 3 citations
  Direct functional interaction of the kinesin-13 family member kinesin-like protein 2A (Kif2A) and Arf GAP with GTP-binding protein-like, ankyrin repeats and PH domains...
  Ruibai Luo, Pei-Wen Chen, Michael Wagenbach, Xiaoying Jian, Lisa Jenkins, Linda Wordeman, Paul A Randazzo> ;The Journal of Biological Chemistry. 2016 Dec 2
• 2 citations
  Direct Functional Interaction of the Kinesin-13 Family Member Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains...
  Ruibai Luo, Pei-Wen Chen, Michael Wagenbach, Xiaoying Jian, Lisa Jenkins, Linda Wordeman, Paul A Randazzo> ;The Journal of Biological Chemistry. 2016 Oct 7
• 11 citations
  Allosteric properties of PH domains in Arf regulatory proteins.
  Neeladri Sekhar Roy, Marielle E. Yohe, Paul A. Randazzo, James M. Gruschus> ;Cellular Logistics. 2016 Apr 26
• 23 citations
  The Arf GTPase-activating Protein, ASAP1, Binds Nonmuscle Myosin 2A to Control Remodeling of the Actomyosin Network *
  Pei-Wen Chen, Xiaoying Jian, Sarah M. Heissler, Kang Le, Ruibai Luo, Lisa M. Miller Jenkins, Attila Nagy, Joel Moss, James R. Sellers, Paul A. Randazzo> ;The Journal of Biological Chemistry. 2016 Apr 1
• 21 citations
  Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.
  Shengjian Li, Yu-He Liang, Jennifer Mariano, Meredith B. Metzger, Daniel K. Stringer, Ventzislava A. Hristova, Jess Li, Paul A. Randazzo, Yien Che Tsai, Xinhua Ji, All...> ;The Journal of Biological Chemistry. 2015 Dec 18
• 49 citations
  Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.
  Xiaoying Jian, Wai-Kwan Tang, Peng Zhai, Neeladri Sekhar Roy, Ruibai Luo, James M. Gruschus, Marielle E. Yohe, Pei-Wen Chen, Yifei Li, R. Andrew Byrd, Di Xia, Paul A. ...> ;Structure. 2015 Nov 3
• Simple in vitro assay of Arf GAPs and preparation of Arf proteins as substrates.
  Pei-Wen Chen, Xiaoying Jian, Ruibai Luo, Paul A. Randazzo> ;Methods in Cell Biology. 2015 Jan 1
• 16 citations
  Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease
  Jinbin Zhai, Lei Zhang, Jelena Mojsilovic-Petrovic, Xiaoying Jian, Jeff D. Thomas, Kengo Homma, Anton Schmitz, Michael Famulok, Hidenori Ichijo, Yair Argon, Paul A. Ra...> ;The Journal of Neuroscience. 2015 Jun 17
• 1 citations
  ArfGAPs: key regulators for receptor sorting.
  Yoko Shiba, Paul A. Randazzo> ;Receptors & Clinical Investigation. 2014 Jun 13
• 33 citations
  Activation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling.
  I-Chung Lo, Vijay Gupta, Krishna Midde, Vanessa Taupin, Inmaculada Lopez-Sanchez, Irina Kufareva, Ruben Abagyan, Paul A. Randazzo, Marilyn G. Farquhar, Pradipta Ghosh> ;Developmental Cell. 2015 Apr 20
• 34 citations
  The Arf6 GTPase-activating proteins ARAP2 and ACAP1 define distinct endosomal compartments that regulate integrin α5β1 traffic.
  Pei-Wen Chen, Ruibai Luo, Xiaoying Jian, Paul A. Randazzo> ;The Journal of Biological Chemistry. 2014 Oct 31
• 1 citations
  The Importance of Seeing Surface (Effects)
  James M. Gruschus, R. Andrew Byrd, Paul A. Randazzo> ;Structure. 2014 Mar 4
• 20 citations
  ArfGAP3 regulates the Transport of Cation-Independent Mannose 6-phosphate Receptor in the post-Golgi compartment
  Yoko Shiba, Satoshi Kametaka, Satoshi Waguri, John F. Presley, Paul A. Randazzo> ;Current Biology. 2013 Oct 7
• 2 citations
  Journey to the ends of the Arf.
  James M. Gruschus, Pei-Wen Chen, Ruibai Luo, Paul A. Randazzo> ;Structure. 2009 Jan 14
• 31 citations
  The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H+-ATPase (V-ATPase) and Cytohesin-2
  Hiroyuki Hosokawa, Phat Vinh Dip, Maria Merkulova, Anastasia Bakulina, Zhenjie Zhuang, Ashok Khatri, Xiaoying Jian, Shawn M. Keating, Stephanie A. Bueler, John L. Rubi...> ;The Journal of Biological Chemistry. 2013 Feb 22
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