Pavel Klein MD

Clinical Trials

• Study to Assess the Safety and Tolerability of Intravenous Carbamazepine in Adults With Epilepsy Start of enrollment: 2010 Jun 01

  Completed

  Phase 3

• Ketogenic Diet as Adjunctive Treatment in Refractory/End-stage Glioblastoma Multiforme: a Pilot Study Start of enrollment: 2013 Jan 01

  Completed

  Phase 1

• Efficacy and Safety of Ketogenic Diet as Adjunctive Treatment in Adults With Refractory Epilepsy Start of enrollment: 2013 Jan 01

  Unknown status

  Phase 2

• Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension Start of enrollment: 2013 Oct 01

  Completed

  Phase 3

• Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea Start of enrollment: 2014 Jan 01

  Unknown status

  Phase 2

• Safety and Pharmacokinetic Study of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures Start of enrollment: 2016 Aug 03

  Completed

  Phase 3

• Perampanel for Treatment of Adults With Refractory Focal Epilepsy : a Pilot Study. Start of enrollment: 2015 Nov 01

  Terminated

  Phase 4

• Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Generalized Seizures or With Primary Generalized Tonic-Clonic Seizures Start of enrollment: 2017 Aug 23

  Completed

  Phase 4

• Treatment of Type 2 Diabetes With Ketogenic Diet Start of enrollment: 2017 Nov 01

  Unknown status

  Not Applicable

• Prospective Open-label Evaluation of Cenobamate Adjunctive Treatment of Adults With Refractory Focal Epilepsy Start of enrollment: 2020 Jun 25

  Recruiting

• A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome Start of enrollment: 2022 Mar 04

  TERMINATED

  PHASE3

  Roles: Principal Investigator

• Clobazam Adjunctive Treatment of Adults With Refractory Focal Epilepsy Start of enrollment: 2015 Feb 01

  Unknown status

  Phase 4

  Roles: Principal Investigator, Contact, Sponsor-Investigator

• A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome Start of enrollment: 2021 Nov 08

  COMPLETED

  PHASE3

  Roles: Principal Investigator

• A Trial of the Efficacy and Safety of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures Start of enrollment: 2020 Jan 27

  COMPLETED

  PHASE2

  Roles: Contact

• Safety, Tolerability, and Exploratory Efficacy of Adjunctive EQU-001 for Seizures in Adults With Epilepsy Start of enrollment: 2021 Aug 31

  Active, not recruiting

  Phase 2

  Roles: Contact

• Placebo-Controlled, Double-Blind, Study to Determine the Safety and Efficacy of SDX in Patients With IH Start of enrollment: 2022 Dec 28

  COMPLETED

  PHASE2

  Roles: Contact

• Cortical Excitability in Post-traumatic Epilepsy Start of enrollment: 2022 Aug 01

  Recruiting

  Roles: Contact, Principal Investigator

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