PeterNelsonBowersMD

PubMed

• 5 citations
  Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling
  Heather A. Himburg, Martina Roos, Tiancheng Fang, Yurun Zhang, Mindy M. Kim, Amara Pang, Jenny Kan, Liman Zhao, Hyung Chan Suh, Joshua P. Sasine, Gopal Sapparapu, Pete...> ;The Journal of Clinical Investigation. 2019 Oct 15
• 7 citations
  The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies
  Peter Bowers, William J Boyle, Robert Damoiseaux> ;Methods in Molecular Biology. 2018 Jan 1
• 33 citations
  A Randomized, Open-Label, Multicenter, Phase III Study of Epoetin Alfa Versus Best Standard of Care in Anemic Patients With Metastatic Breast Cancer Receiving Standard...
  Brian Leyland-Jones, Igor Bondarenko, Gia Nemsadze, Vitaliy Smirnov, Iryna Litvin, Irakli Kokhreidze, Lia Abshilava, Mikheil Janjalia, Rubi Li, Kuntegowda C. Lakshmaia...> ;Journal of Clinical Oncology. 2016 Sep 27
• 16 citations
  Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.
  Peter Bowers, Petra Verdino, Zhengyuan Wang, Jean da Silva Correia, Mark Chhoa, Griffin Macondray, Minjee Do, Tamlyn Y. Neben, Robert A. Horlick, Robyn L. Stanfield, I...> ;The Journal of Biological Chemistry. 2014 Nov 28
• 40 citations
  A general approach to antibody thermostabilization.
  Audrey D. McConnell, Xue Zhang, John L. Macomber, Betty Chau, Joseph C. Sheffer, Sorena Rahmanian, Eric Hare, Vladimir Spasojevic, Robert A. Horlick, David J. King, Pe...> ;Mabs. 2014 Oct 30
• 22 citations
  Mammalian Cell Display and Somatic Hypermutation In Vitro for Human Antibody Discovery
  David J. King, Peter Bowers, Marilyn Kehry, Robert A. Horlick> ;Current Drug Discovery Technologies. 2014 Feb 28
• 49 citations
  Mammalian cell display for the discovery and optimization of antibody therapeutics.
  Peter Bowers, Robert A. Horlick, Marilyn Kehry, Tamlyn Y. Neben, Geoffery L. Tomlinson, Larry Altobell, Xue Zhang, John L. Macomber, Irina P. Krapf, Betty F. Wu, Audre...> ;Methods. 2014 Jan 1
• 28 citations
  Simultaneous surface display and secretion of proteins from mammalian cells facilitate efficient in vitro selection and maturation of antibodies.
  Robert A. Horlick, John L. Macomber, Peter Bowers, Tamlyn Y. Neben, Geoffery L. Tomlinson, Irina P. Krapf, Jennifer L. Dalton, Petra Verdino, David J. King> ;The Journal of Biological Chemistry. 2013 Jul 5
• 15 citations
  Humanization of Antibodies Using Heavy Chain Complementarity-determining Region 3 Grafting Coupled with in Vitro Somatic Hypermutation
  Peter Bowers, Tamlyn Y. Neben, Geoffery L. Tomlinson, Jennifer L. Dalton, Larry Altobell, Xue Zhang, John L. Macomber, Betty F. Wu, Rachelle M. Toobian, Audrey D. McCo...> ;The Journal of Biological Chemistry. 2013 Mar 15
• 46 citations
  An integrated approach to extreme thermostabilization and affinity maturation of an antibody
  Audrey D. McConnell, Vladimir Spasojevich, John L. Macomber, Irina P. Krapf, Andy P. Chen, Joseph C. Sheffer, Ashley D. Berkebile, Robert A. Horlick, Steven S. Neben, ...> ;Protein Engineering, Design & Selection. 2013 Feb 1
• 22 citations
  High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation.
  Audrey D. McConnell, Minjee Do, Tamlyn Y. Neben, Vladimir Spasojevic, Josh MacLaren, Andy P. Chen, Laurence Altobell, John L. Macomber, Ashley D. Berkebile, Robert A. ...> ;Plos One. 2012 Nov 14
• 77 citations
  Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies
  Peter Bowers, Robert A. Horlick, Tamlyn Y. Neben, Rachelle M. Toobian, Geoffrey L. Tomlinson, Jennifer L. Dalton, Heather A. Jones, Andy P. Chen, Laurence Altobell, Xu...> ;Proceedings of the National Academy of Sciences of the United States of America. 2011 Dec 20
• 9 citations
  A Randomized Controlled Study Comparing Once-Weekly to Every-2-Week and Every-4-Week Dosing of Epoetin Alfa in CKD Patients with Anemia
  Pablo E. Pergola, Gary Gartenberg, Min Fu, Steven Sun, Marsha Wolfson, Peter Bowers> ;Clinical Journal of the American Society of Nephrology. 2010 Apr 1
• 169 citations
  Erythropoiesis-stimulating agents in oncology: a study-level meta-analysis of survival and other safety outcomes.
  John A. Glaspy, Jeffrey Crawford, Johan Vansteenkiste, David H. Henry, S. Rao, Peter Bowers, J A Berlin, Dianne Tomita, Ken Bridges, Heinz Ludwig> ;British Journal of Cancer. 2010 Jan 19
• 15 citations
  A Randomized Controlled Study of Weekly and Biweekly Dosing of Epoetin Alfa in CKD Patients With Anemia
  Pablo E. Pergola, Gary Gartenberg, Min Fu, Marsha Wolfson, Sudhakar Rao, Peter Bowers> ;Clinical Journal of the American Society of Nephrology. 2009 Nov 1
• 57 citations
  Cumulative ligand activity of NODAL mutations and modifiers are linked to human heart defects and holoprosencephaly.
  Erich Roessler, Wuhong Pei, Maia Ouspenskaia, Jayaprakash D. Karkera, Jorge I. Vélez, Sharmilla Banerjee-Basu, Gretchen Gibney, Philip J. Lupo, Laura E. Mitchell, Jeff...> ;Molecular Genetics and Metabolism. 2009 Oct 1
• 111 citations
  Reduced NODAL signaling strength via mutation of several pathway members including FOXH1 is linked to human heart defects and holoprosencephaly.
  Erich Roessler, Maia Ouspenskaia, Jayaprakash D. Karkera, Jorge I. Vélez, Amy Kantipong, Felicitas Lacbawan, Peter Bowers, John W. Belmont, Jeffrey A. Towbin, Elizabet...> ;American Journal of Human Genetics. 2008 Jul 11
• 87 citations
  Loss-of-Function Mutations in Growth Differentiation Factor-1 (GDF1) Are Associated with Congenital Heart Defects in Humans
  Jayaprakash D. Karkera, Joon S. Lee, Erich Roessler, Sharmila Banerjee-Basu, Maia Ouspenskaia, Jesse Mez, Elizabeth Goldmuntz, Peter Bowers, Jeffrey A. Towbin, John W....> ;American Journal of Human Genetics. 2007 Nov 1
• 19 citations
  Hair analysis in sled dogs (Canis lupus familiaris) illustrates a linkage of mercury exposure along the Yukon River with human subsistence food systems.
  Kriya L. Dunlap, Arleigh J. Reynolds, Peter Bowers, Lawrence K. Duffy> ;The Science of the Total Environment. 2007 Oct 15
• 3 citations
  Functional Linkages Can Reveal Protein Complexes for Structure Determination
  Sul-Min Kim, Peter Bowers, Debnath Pal, Michael J. Strong, Thomas C. Terwilliger, Markus Kaufmann, David Eisenberg> ;Structure. 2007 Sep 11
• 10 citations
  Natural history of anemia associated with interferon/ribavirin therapy for patients with HIV/HCV coinfection.
  David H. Henry, Jihad Slim, Anthony Lamarca, Peter Bowers, Gerhard Leitz> ;AIDS Research and Human Retroviruses. 2007 Jan 31
• 28 citations
  The Structure and Computational Analysis of Mycobacterium tuberculosis Protein CitE Suggest a Novel Enzymatic Function
  Celia W. Goulding, Peter Bowers, Brent W. Segelke, T. Lekin, Chang-Yub Kim, Thomas C. Terwilliger, David Eisenberg> ;Journal of Molecular Biology. 2007 Jan 12
• 4 citations
  An exploratory study of total mercury levels in archaeological caribou hair from northwest alaska
  S. Craig Gerlach, Lawrence K. Duffy, Maribeth S. Murray, Peter Bowers, Rachel Adams, David A. Verbrugge> ;Chemosphere. 2006 Dec 1
• 148 citations
  A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y
  Leigh D. Plant, Peter N. Bowers, Qianyong Liu, Thomas M. Morgan, Tingting Zhang, Matthew W. State, Weidong Chen, Rick A. Kittles, Steve A.N. Goldstein> ;The Journal of Clinical Investigation. 2006 Feb 1
• 19 citations
  Utilizing logical relationships in genomic data to decipher cellular processes
  Peter Bowers, Brian O'Connor, Shawn J. Cokus, Einat Sprinzak, Todd O. Yeates, David Eisenberg> ;The FEBS Journal. 2005 Oct 1
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