PeterJCastaldiMD

PubMed

• Biosurfer for systematic tracking of regulatory mechanisms leading to protein isoform diversity.
  Mayank Murali, Jamie Saquing, Senbao Lu, Ziyang Gao, Ben Jordan, Zachary Peters Wakefield, Ana Fiszbein, David R Cooper, Dmitry Korkin, Gloria Sheynkman, Peter J Castaldi> ;Biorxiv. 2024 Mar 17
• Predictors of Nicotine Replacement Therapy Adherence: Mixed-Methods Research With a Convergent Parallel Design.
  Sun S Kim, Anyah Prasad, Manan M Nayak, Hua Chen, Chaowalit Srisoem, Rosanna F DeMarco, Peter Castaldi, Mary E Cooley> ;Annals of Behavioral Medicine. 2024 Mar 12
• A Generalized Higher-order Correlation Analysis Framework for Multi-Omics Network Inference.
  Liu, W., Pratte, K., Hersh, C., Banaei-Kashani, F., Kechris, K., Castaldi, P., Bowler, R.> ;Biorxiv. 2024 Jan 25
• Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores.
  Hrytsenko, Y., Shea, B., Elgart, M., Kurniansyah, N., Lyons, G., Morrison, A., Carson, A., Haring, B., Mitchel, B., Psaty, B., Jaeger, B., Gu, C., Kooperberg, C., Levy...> ;Medrxiv. 2023 Dec 14
• 1 citations
  Activation of CD8T Cells in Chronic Obstructive Pulmonary Disease Lung.
  Ana B Villaseñor-Altamirano, Dhawal Jain, Yunju Jeong, Jaivardhan A Menon, Mari Kamiya, Hibah Haider, Reshmi Manandhar, Muhammad Dawood Amir Sheikh, Humra Athar, Louis...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Dec 1
• 1 citations
  Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants.
  Jonah Einson, Dafni Glinos, Eric Boerwinkle, Peter Castaldi, Dawood Darbar, Mariza de Andrade, Patrick Ellinor, Myriam Fornage, Stacey Gabriel, Soren Germer, Richard G...> ;Genetics. 2023 Aug 9
• Deep Learning Integration of Chest Computed Tomography Imaging and Gene Expression Identifies Novel Aspects of COPD.
  Junxiang Chen, Zhonghui Xu, Li Sun, Ke Yu, Craig P Hersh, Adel Boueiz, John E Hokanson, Frank C Sciurba, Edwin K Silverman, Peter J Castaldi, Kayhan Batmanghelich> ;Chronic Obstructive Pulmonary Diseases. 2023 Oct 26
• 1 citations
  Heterogeneity and Progression of Chronic Obstructive Pulmonary Disease: Emphysema-Predominant and Non-Emphysema-Predominant Disease.
  Peter J Castaldi, Zhonghui Xu, Kendra A Young, John E Hokanson, David A Lynch, Stephen M Humphries, James C Ross, Michael H Cho, Craig P Hersh, James D Crapo, Matthew ...> ;American Journal of Epidemiology. 2023 Oct 10
• Integrating Genetics, Transcriptomics, and Proteomics in Lung Tissue to Investigate Chronic Obstructive Pulmonary Disease.
  Yu-Hang Zhang, Michael H Cho, Jarrett D Morrow, Peter J Castaldi, Craig P Hersh, Mukul K Midha, Michael R Hoopmann, Sharon M Lutz, Robert L Moritz, Edwin K Silverman> ;American Journal of Respiratory Cell and Molecular Biology. 2023 Jun 1
• 1 citations
  Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants.
  Jonah Einson, Dafni Glinos, Eric Boerwinkle, Peter Castaldi, Dawood Darbar, Mariza de Andrade, Patrick Ellinor, Myriam Fornage, Stacey Gabriel, Soren Germer, Richard G...> ;Biorxiv. 2023 Jan 31
• 3 citations
  Hepatitis C and HIV detection by blood RNA-sequencing in cohort of smokers.
  Jarrett D Morrow, Peter J Castaldi, Robert P Chase, Jeong H Yun, Gregory L Kinney, Edwin K Silverman, Craig P Hersh> ;Scientific Reports. 2023 Jan 24
• 1 citations
  Protocol for a randomized controlled trial of the Enhanced Smoking Cessation Approach to Promote Empowerment (ESCAPE) digitalized intervention to promote lung health i...
  Mary E Cooley, Peter J Castaldi, Emanuele Mazzola, Meghan Underhill Blazey, Manan M Nayak, Michael J Healey, Christopher S Lathan, Andrea Borondy-Kitts, Rosanna F DeMa...> ;Contemporary Clinical Trials. 2023 Jan 1
• 8 citations
  Bridging the splicing gap in human genetics with long-read RNA sequencing: finding the protein isoform drivers of disease.
  Peter J Castaldi, Abdullah Abood, Charles R Farber, Gloria M Sheynkman> ;Human Molecular Genetics. 2022 Oct 20
• 1 citations
  Clustering-based COPD subtypes have distinct longitudinal outcomes and multi-omics biomarkers.
  Andrew Gregory, Zhonghui Xu, Katherine Pratte, Sool Lee, Congjian Liu, Robert Chase, Jeong Yun, Aabida Saferali, Craig P Hersh, Russell Bowler, Edwin Silverman, Peter ...> ;BMJ Open Respiratory Research. 2022 Aug 1
• Blood gene expression risk profiles and interstitial lung abnormalities: COPDGene and ECLIPSE cohort studies.
  Matthew Moll, Brian D Hobbs, Aravind Menon, Auyon J Ghosh, Rachel K Putman, Takuya Hino, Akinori Hata, Edwin K Silverman, John Quackenbush, Peter J Castaldi, Craig P H...> ;Respiratory Research. 2022 Jun 17
• 2 citations
  Machine Learning Prediction of Progression in Forced Expiratory Volume in 1 Second in the COPDGene® Study.
  Adel Boueiz, Zhonghui Xu, Yale Chang, Aria Masoomi, Andrew Gregory, Sharon M Lutz, Dandi Qiao, James D Crapo, Jennifer G Dy, Edwin K Silverman, Peter J Castaldi> ;Chronic Obstructive Pulmonary Diseases. 2022 Jul 29
• 1 citations
  Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.
  Auyon J Ghosh, Brian D Hobbs, Jeong H Yun, Aabida Saferali, Matthew Moll, Zhonghui Xu, Robert P Chase, Jarrett Morrow, John Ziniti, Frank Sciurba, Lucas Barwick, Andre...> ;Respiratory Research. 2022 Apr 21
• 30 citations
  Enhanced protein isoform characterization through long-read proteogenomics.
  Rachel M Miller, Ben T Jordan, Madison M Mehlferber, Erin D Jeffery, Christina Chatzipantsiou, Simi Kaur, Robert J Millikin, Yunxiang Dai, Simone Tiberi, Peter J Casta...> ;Genome Biology. 2022 Mar 3
• 3 citations
  Alternative poly-adenylation modulates α1-antitrypsin expression in chronic obstructive pulmonary disease.
  Lela Lackey, Aaztli Coria, Auyon J. Ghosh, Phil Grayeski, Luke Hatfield, Vijay Shankar, John Platig, Zhonghui Xu, Silvia B. V. Ramos, Edwin K. Silverman, Victor E Orte...> ;Plos Genetics. 2021 Nov 16
• 2 citations
  Cigarette smoking-associated isoform switching and 3' UTR lengthening via alternative polyadenylation.
  Zhonghui Xu, John Platig, Sool Lee, Adel Boueiz, Rob Chase, Dhawal Jain, Andrew Gregory, Rahul Suryadevara, Seth Berman, Russell P. Bowler, Craig P. Hersh, Alain Laede...> ;Genomics. 2021 Nov 8
• 2 citations
  Development of A Blood-Based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease
  Matthew Moll, Adel Boueiz, Auyon J. Ghosh, Aabida Saferali, Sool Lee, Zhonghui Xu, Jeong H. Yun, Brian D. Hobbs, Craig P. Hersh, Don D. Sin, Ruth Tal-Singer, Edwin K. ...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Nov 5
• 10 citations
  Lung proteomic biomarkers associated with chronic obstructive pulmonary disease
  Yu-Hang Zhang, Michael R. Hoopmann, Peter J. Castaldi, Kirsten A. Simonsen, Mukul K. Midha, Michael H. Cho, Gerard J. Criner, Raphael Bueno, Jiangyuan Liu, Robert L. M...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2021 Apr 10
• 5 citations
  An interferon inducible signature of airway disease from blood gene expression profiling
  Jeong H. Yun, Sool Lee, Pooja Srinivasa, Jarrett D. Morrow, Robert P. Chase, Aadbida Saferali, Zhonghui Xu, Michael H. Cho, Peter J. Castaldi, Craig P. Hersh> ;The European Respiratory Journal. 2021 Oct 14
• 5 citations
  Improved prediction of smoking status via isoform-aware RNA-seq deep learning models.
  Zifeng Wang, Aria Masoomi, Zhonghui Xu, Adel Boueiz, Sool Lee, Tingting Zhao, Russell P. Bowler, Michael H. Cho, Edwin K. Silverman, Craig P. Hersh, Jennifer G. Dy, Pe...> ;Plos Computational Biology. 2021 Oct 11
• 6 citations
  Peripheral blood microbial signatures in current and former smokers
  Jarrett D. Morrow, Peter J. Castaldi, Robert P. Chase, Jeong H. Yun, Sool Lee, Yang-Yu Liu, Craig P. Hersh> ;Scientific Reports. 2021 Oct 6
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