PeterMannonMDMPH

Gastroenterology • Birmingham, AL

Inflammatory Bowel Disease

Professor, Medicine, University of Alabama School of Medicine

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Office
2000 6th Ave S
Birmingham, AL 35233
Phone+1 205-934-9999

Fax+1 205-801-8668
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Education & Training

Duke University HospitalFellowship, Gastroenterology, 1987 - 1989
Johns Hopkins UniversityFellowship, Gastroenterology, 1986 - 1987
Duke University HospitalResidency, Internal Medicine, 1983 - 1986
Boston University School of MedicineClass of 1983

Certifications & Licensure

SD State Medical License Active through 2025
KS State Medical License 2023 - 2024
AL State Medical License 2008 - 2024
NC State Medical License 1985 - 2024
IA State Medical License 2023 - 2024
NE State Medical License 2020 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Gastroenterology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Clinical Trials

Study of STA-5326 Mesylate in Patients With Moderate to Severe Crohn's Disease Start of enrollment: 2005 Nov 01
Completed
Phase 2

Publications & Presentations

PubMed

Gastrointestinal bleeding and pro-angiogenic shift in the angiopoietin axis with continuous flow left ventricular assist device implantation.
Adam L Edwards, C Mel Wilcox, Mark Beasley, Salpy V Pamboukian, Peter Mannon, Shajan Peter> ;The American Journal of the Medical Sciences. 2023 Oct 1
2 citations
The relationship between nutrition, gut dysbiosis, and pediatric sickle cell pain outcomes: A pilot study.
Chinenye R Dike, Corrine Hanson, H Dele Davies, Stephen Obaro, Fang Yu, James Harper, Helen Grace, Jeffrey Lebensburger, Chittalsinh Raulji, Jihyun Ma, Peter Mannon> ;Pediatric Blood & Cancer. 2023 Jul 1
Monkeypox Manifesting as Rectal Pain and Constipation.
Jessica Larson, Alexander Praus, Peter Mannon> ;ACG Case Reports Journal. 2022 Dec 1
4 citations
Crohn's Disease Patients Uniquely Contain Inflammatory Responses to Flagellin in a CD4 Effector Memory Subset.
Nadine N Morgan, Lennard W Duck, Jiongru Wu, Mahmud Rujani, Paul G Thomes, Charles O Elson, Peter J Mannon> ;Inflammatory Bowel Diseases. 2022 Dec 1
Celiac disease and the surgeon.
Jon S Thompson, Peter Mannon> ;American Journal of Surgery. 2022 Jul 1
37 citations
Human Microbiota Flagellins Drive Adaptive Immune Responses in Crohn's Disease.
Katie L. Alexander, Qing Zhao, Meagan Reif, Alexander F. Rosenberg, Peter J. Mannon, L.W. Duck, Charles O. Elson> ;Gastroenterology. 2021 Aug 1
15 citations
Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease.
Hari K. Somineni, Sini Nagpal, Suresh Venkateswaran, David J. Cutler, David T. Okou, Talin Haritunians, Claire L. Simpson, Ferdouse Begum, Lisa W. Datta, Antonio Quiro...> ;American Journal of Human Genetics. 2021 Mar 4
5 citations
Flagellin-Specific CD4 Cytokine Production in Crohn Disease and Controls Is Limited to a Small Subset of Antigen-Induced CD40L+ T Cells.
Nadine Morgan, Peter J. Mannon> ;Journal of Immunology. 2021 Jan 15
28 citations
CD4+ T cell activation and concomitant mTOR metabolic inhibition can ablate microbiota-specific memory cells and prevent colitis.
Qing Zhao, L.W. Duck, Fengyuan Huang, Katie L. Alexander, Craig L. Maynard, Peter J. Mannon, Charles O. Elson> ;Science Immunology. 2020 Dec 11
16 citations
Mucosa-Associated Microbiota in Barrett's Esophagus, Dysplasia, and Esophageal Adenocarcinoma Differ Similarly Compared With Healthy Controls.
Shajan Peter, Amanda Pendergraft, William VanDerPol, C. Mel Wilcox, Kondal R. Kyanam Kabir Baig, Casey D. Morrow, Jacques Izard, Peter J. Mannon> ;Clinical and Translational Gastroenterology. 2020 Aug 1
2 citations
Systemic antibody responses to gut commensal bacteria: How and why do I know you?
Peter J. Mannon> ;The Journal of Allergy and Clinical Immunology. 2019 Apr 1
13 citations
Expanded TCRβ CDR3 clonotypes distinguish Crohn’s disease and ulcerative colitis patients
J. Wu, A. H. Pendegraft, M. Byrne-Steele, Q. Yang, C. Wang, W. Pan, T. Lucious, Toni Seay, X. Cui, Charles O. Elson, J. Han, Peter J. Mannon> ;Mucosal Immunology. 2018 Jul 9
94 citations
Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease
Steven R. Brant, David T. Okou, Claire L. Simpson, David J. Cutler, Talin Haritunians, Jonathan P. Bradfield, Pankaj Chopra, Jarod Prince, Ferdouse Begum, Archana Kuma...> ;Gastroenterology. 2017 Jan 1
40 citations
Human seroreactivity to gut microbiota antigens
Benjamin S. Christmann, Thomas Abrahamsson, Charles N. Bernstein, L. Wayne Duck, Peter J. Mannon, Göran Berg, Bengt Björkstén, Maria C. Jenmalm, Charles O. Elson> ;The Journal of Allergy and Clinical Immunology. 2015 Nov 1
54 citations
Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans
Chengrui Huang, Talin Haritunians, David T. Okou, David J. Cutler, Michael E. Zwick, Kent D. Taylor, Lisa W. Datta, Joseph C. Maranville, Zhenqiu Liu, Shannon E. Ellis...> ;Gastroenterology. 2015 Nov 1
39 citations
Human Gastric Epithelial Cells Contribute to Gastric Immune Regulation by Providing Retinoic Acid to Dendritic Cells
Diane Bimczok, John Y. Kao, Min Zhang, Steven Cochrun, Peter J. Mannon, Shajan Peter, Charles M. Wilcox, Klaus Mönkemüller, Paul R. Harris, Jayleen Grams, Richard Stah...> ;Mucosal Immunology. 2015 May 1
Body Mass Index Is Associated With Mucosal Disease in Crohn's: Results of a Case-Control Study.
Talha A. Malik, Richard A. Kaslow, Stacey S. Cofield, Peter J. Mannon> ;Gastroenterology Research. 2014 Dec 27
62 citations
IL-13Rα2-bearing, type II NKT cells reactive to sulfatide self-antigen populate the mucosa of ulcerative colitis
Ivan J. Fuss, Bharat H. Joshi, Zhiqiong Yang, Heba A. Degheidy, Stefan Fichtner-Feigl, Heitor Siffert Pereira de Souza, Florian Rieder, Franco Scaldaferri, Anja Schirb...> ;Gut. 2014 Nov 1
44 citations
The Microbiota, the Immune System and the Allograft
Maria-Luisa Alegre, Roslyn B. Mannon, Peter J. Mannon> ;American Journal of Transplantation. 2014 Jun 1
Republished: Interleukin 13 and its role in gut defence and inflammation.
Mannon, P.,Reinisch, W.> ;Postgrad Med J. 2013 Aug
20 citations
Helicobacter pylori Infection Inhibits Phagocyte Clearance of Apoptotic Gastric Epithelial Cells
Diane Bimczok, Lesley E. Smythies, Ken B. Waites, Jayleen Grams, Richard Stahl, Peter J. Mannon, Shajan Peter, C. Mel Wilcox, Paul R. Harris, Soumita Das, Peter B. Ern...> ;Journal of Immunology. 2013 Jun 15
37 citations
Extracorporeal photopheresis (ECP) in patients with steroid‐dependent Crohn's disease: An open‐label, multicenter, prospective trial
Walter Reinisch, Robert Knobler, Paul Rutgeerts, Thomas Ochsenkühn, Frank H. Anderson, Christian von Tirpitz, Martin Kaatz, C. Janneke van der Woude, Dennis Parenti, P...> ;Inflammatory Bowel Diseases. 2013 Feb 1
82 citations
Interleukin 13 and its role in gut defence and inflammation
Peter J. Mannon, Walter Reinisch> ;Gut. 2012 Jan 1
34 citations
Complement-Dependent Injury and Protection in a Murine Model of Acute Dextran Sulfate Sodium-Induced Colitis
Jennifer Schepp-Berglind, Carl Atkinson, Michelle Elvington, Fei Qiao, Peter J. Mannon, Stephen Tomlinson> ;Journal of Immunology. 2012 Jun 15
7024 citations
Structure, function and diversity of the healthy human microbiome
Curtis Huttenhower, Dirk Gevers, Rob Knight, Sahar Abubucker, Jonathan H. Badger, Asif T. Chinwalla, Heather Huot Creasy, Ashlee M. Earl, Michael Fitzgerald, Robert S....> ;Nature. 2012 Jun 14
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Press Mentions

4 Gastroenterology Leaders on the MoveFebruary 10th, 2020
A Bevy of Physician Moves & More: 5 GI Industry Key NotesDecember 4th, 2019
Two New Leaders in Internal Medicine to Arrive Feb. 1October 29th, 2019
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Grant Support

Clinical Studies Of Inflammatory Bowel DiseasesNational Institute Of Allergy And Infectious Diseases2005–2007
The Immune Basis For The Gastrointestinal ComplicationsNational Institute Of Allergy And Infectious Diseases2002–2004
Granulocyte Colony Stimulating Factor Treatment For CrohNational Institute Of Allergy And Infectious Diseases2002–2004
Study Of Human Monoclonal Antibody To IL-12 For TreatmenNational Institute Of Allergy And Infectious Diseases2002
Antibody To IL12 For Treatment Of Crohn'S DiseaseNational Institute Of Allergy And Infectious Diseases2001

Hospital Affiliations

Nebraska Medicine - Nebraska Medical CenterOmaha, Nebraska
USA Health University HospitalMobile, Alabama