PradeepNatarajanMDMMSc

PubMed

• Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk.
  Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Michael C Honigberg, Mustafa Yalcinkaya, Tetsushi Nakao, Ashley Pournamadri, Tong Xiao, Mohammad ...> ;Blood. 2024 Apr 11
• Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1.
  Seyedmohammad Saadatagah, Mohammadreza Naderian, Mesbah Uddin, Ozan Dikilitas, Abhishek Niroula, Art Schuermans, Elizabeth Selvin, Ron C Hoogeveen, Kunihiro Matsushita...> ;JAMA Cardiology. 2024 Apr 10
• Coronary Microvascular Function Following Severe Preeclampsia.
  Michael C Honigberg, Katherine E Economy, Maria A Pabón, Xiaowen Wang, Claire Castro, Jenifer M Brown, Sanjay Divakaran, Brittany N Weber, Leanne Barrett, Anna Perillo...> ;Hypertension. 2024 Apr 2
• Genetic variation across and within individuals.
  Zhi Yu, Tim H H Coorens, Md Mesbah Uddin, Kristin G Ardlie, Niall Lennon, Pradeep Natarajan> ;Nature Reviews. Genetics. 2024 Mar 28
• Polygenic Scores and Preclinical Cardiovascular Disease in Individuals With HIV: Insights From the REPRIEVE Trial.
  Yunfeng Ruan, Buu Truong, Michael T Lu, Júlia Karády, Rachel Bernardo, Phoebe Finneran, Whitney Hornsby, Kathleen V Fitch, Heather J Ribaudo, Pamela S Douglas, Steven ...> ;Journal of the American Heart Association. 2024 Apr 2
• Deep Learning to Estimate Cardiovascular Risk From Chest Radiographs : A Risk Prediction Study.
  Jakob Weiss, Vineet K Raghu, Aniket Zinzuwadia, Hugo J W L Aerts, Kaavya Paruchuri, Pradeep Natarajan, Michael T Lu> ;Annals of Internal Medicine. 2024 Apr 1
• Lipid levels and risk of acute pancreatitis using bidirectional Mendelian randomization.
  Biqi Wang, Jacqueline S Dron, Yuxuan Wang, Seung Hoan Choi, Jennifer E Huffman, Kelly Cho, Peter W F Wilson, Gina M Peloso, Pradeep Natarajan> ;Scientific Reports. 2024 Mar 15
• Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases.
  Buu Truong, Yunfeng Ruan, Qin Qin Huang, Whitney Hornsby, Hilary Martin, David A van Heel, Alicia R Martin, S Hong Lee, Leland E Hull, Ying Wang, Pradeep Natarajan> ;Cell Genomics. 2024 Apr 10
• Coronary Microvascular Function Following Severe Preeclampsia.
  Michael C Honigberg, Katherine E Economy, Maria A Pabón, Xiaowen Wang, Claire Castro, Jenifer M Brown, Sanjay Divakaran, Brittany N Weber, Leanne Barrett, Anna Perillo...> ;Medrxiv. 2024 Mar 5
• Novel Polygenic Risk Score and Established Clinical Risk Factors for Risk Estimation of Aortic Stenosis.
  Aeron M Small, Giorgio E M Melloni, Frederick K Kamanu, Brian A Bergmark, Marc P Bonaca, Michelle L O'Donoghue, Robert P Giugliano, Benjamin M Scirica, Deepak Bhatt, E...> ;JAMA Cardiology. 2024 Apr 1
• Risk factors for clonal hematopoiesis of indeterminate potential in people with HIV: a report from the REPRIEVE trial.
  Bhattacharya, R., Uddin, M., Patel, A., Niroula, A., Finneran, P., Bernardo, R., Fitch, K., Lu, M., Bloomfield, G., Malvestutto, C., Aberg, J., Fichtenbaum, C., Hornsb...> ;Blood Advances. 2024 Feb 27
• Differences in Circulating Progenitor Cells and Risk of Atherosclerotic Cardiovascular Disease in South Asian Individuals.
  Natarajan, P., Patel, A.> ;Journal of the American College of Cardiology. 2024 Feb 20
• Sex Differences in the Association of Multiethnic Genome-Wide Blood Pressure Polygenic Risk Score With Population-Level Systolic Blood Pressure Trajectories.
  Naman S Shetty, Akhil Pampana, Nirav Patel, Krishin Yerabolu, Gnyata Patel, Marguerite R Irvin, Pradeep Natarajan, Henry J Lin, Xiuqing Guo, Stephen S Rich, Jerome I R...> ;Circulation. Genomic and Precision Medicine. 2024 Apr 1
• Clonal Hematopoiesis of Indeterminate Potential With Loss ofEnhances Risk for Atrial Fibrillation ThroughInflammasome Activation.
  Lin, A., Bapat, A., Xiao, L., Niroula, A., Ye, J., Wong, W., Agrawal, M., Farady, C., Boettcher, A., Hergott, C., McConkey, M., Flores-Bringas, P., Shkolnik, V., Bick,...> ;Circulation. 2024 Feb 15
• Lipoprotein(a), C-Reactive Protein, and Cardiovascular Risk in Primary and Secondary Prevention Populations.
  Aeron M Small, Ashley Pournamdari, Giorgio E M Melloni, Benjamin M Scirica, Deepak L Bhatt, Itamar Raz, Eugene Braunwald, Robert P Giugliano, Marc S Sabatine, Gina M P...> ;JAMA Cardiology. 2024 Apr 1
• Lipoprotein(a) Concentrations Are Independent of Polygenic Score for Coronary Artery Disease.
  Michael N Trinh, Gina M Peloso, Ashley Pournamdari, Aeron M Small, Aniruddh P Patel, Pradeep Natarajan> ;JACC. Advances. 2024 Feb 1
• Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol.
  Zhang, Y., Dron, J., Bellows, B., Khera, A., Liu, J., Balte, P., Oelsner, E., Amr, S., Lebo, M., Nagy, A., Peloso, G., Natarajan, P., Rotter, J., Willer, C., Boerwinkl...> ;JAMA Cardiology. 2024 Mar 1
• Phenome- and genome-wide analyses of retinal optical coherence tomography images identify links between ocular and systemic health.
  Zekavat, S., Jorshery, S., Rauscher, F., Horn, K., Sekimitsu, S., Koyama, S., Nguyen, T., Costanzo, M., Jang, D., Burtt, N., Kühnapfel, A., Shweikh, Y., Ye, Y., Raghu,...> ;Science Translational Medicine. 2024 Jan 24
• Complex Genetic Architecture of Spontaneous Coronary Artery Dissection.
  Day, S., Natarajan, P.> ;JAMA Cardiology. 2024 Mar 1
• Radon Exposure, Clonal Hematopoiesis, and Stroke Susceptibility in the Women's Health Initiative.
  Huang, D. Y., Kurtis M Anthony, Jason M Collins, Shelly-Ann M Love, James D Stewart, Sophie F Buchheit, Rahul Gondalia, Gary G Schwartz, David Y Huang, Jaymie R Melike...> ;Neurology. 2024 Jan 23
• Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas.
  Odessica Hughes, Amy R Bentley, Charles E Breeze, Francois Aguet, Xiaoguang Xu, Girish Nadkarni, Quan Sun, Bridget M Lin, Thomas Gilliland, Mariah C Meyer, Jiawen Du, ...> ;Cell Genomics. 2024 Jan 10
• Trends of Lipid Concentrations, Awareness, Evaluation, and Treatment in Severe Dyslipidemia in US Adults.
  Naman S Shetty, Mokshad Gaonkar, Nirav Patel, Joshua W Knowles, Pradeep Natarajan, Garima Arora, Pankaj Arora> ;Mayo Clinic Proceedings. 2024 Feb 1
• 1 citations
  Genetic Associations of Circulating Cardiovascular Proteins With Gestational Hypertension and Preeclampsia.
  Art Schuermans, Buu Truong, Maddalena Ardissino, Rohan Bhukar, Eric A W Slob, Tetsushi Nakao, Jacqueline S Dron, Aeron M Small, So Mi Jemma Cho, Zhi Yu, Whitney Hornsb...> ;JAMA Cardiology. 2024 Mar 1
• Clonal Hematopoiesis Risk Score and All-Cause and Cardiovascular Mortality in Older Adults.
  Seyedmohammad Saadatagah, Md Mesbah Uddin, Lachelle D Weeks, Abhishek Niroula, Meng Ru, Koichi Takahashi, Lukasz Gondek, Bing Yu, Alexander G Bick, Benjamin L Ebert, E...> ;JAMA Network Open. 2024 Jan 2
• Clonal Hematopoiesis and Incident Heart Failure With Preserved Ejection Fraction.
  Schuermans, A., Raffield, L., Yu, B., Roberts, M., Kooperberg, C., Carson, A., Ballantyne, C., Manson, J., Whitsel, E., Eaton, C., Reiner, A., Honigberg, M., Desai, P....> ;JAMA Network Open. 2024 Jan 2
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Journal Articles

• Clinical Utility of Lipoprotein(A) and LPA Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular Disease  
  Pradeep Natarajan, MD, JAMA Cardiology
• Completing the Genetic Spectrum Influencing Coronary Artery Disease: From Germline to Somatic Variation  
  Pradeep Natarajan, MD, Cardiovascular Research
• Recall by Genotype and Cascade Screening for Familial Hypercholesterolemia in a Population-Based Biobank from Estonia  
  Sekar Kathiresan, Pradeep Natarajan, Nature
• DNA Sequence Variation in ACVR1C Encoding the Activin-Receptor like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes  
  Derek Klarin, Pradeep Natarajan, Ruth McPherson, Sekar Kathiresan, Krishna Aragam, Alexander Bick, Diabetes Care
• Genome-Wide Polygenic Scores for Common Diseases Identify Individuals with Risk Equivalent to Monogenic Mutations  
  Amit V Khera, Steven A Lubitz, Sekar Kathiresan, Patrick T Ellinor, Krishna G Aragam, Pradeep Natarajan, Nature
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