PrasannaJagannathanMD

PubMed

• Monthly Sulfadoxine-Pyrimethamine During Pregnancy Prevents Febrile Respiratory Illnesses: A Secondary Analysis of a Malaria Chemoprevention Trial in Uganda.
  Jordan John Lee, Abel Kakuru, Karen B Jacobson, Moses R Kamya, Richard Kajubi, Jade Benjamin-Chung, Grant Dorsey, Michelle E Roh, Anju Ranjit, Stephanie L Gaw, Julie P...> ;Open Forum Infectious Diseases. 2024 Apr 1
• Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda.
  Moses R Kamya, Joaniter I Nankabirwa, Emmanuel Arinaitwe, John Rek, Maato Zedi, Catherine Maiteki-Sebuguzi, Jimmy Opigo, Sarah G Staedke, Ambrose Oruni, Martin J Donne...> ;Medrxiv. 2024 Mar 16
• Atypical B cells consist of subsets with distinct functional profiles.
  Raphael A Reyes, Gayani Batugedara, Paramita Dutta, Ashley B Reers, Rolando Garza, Isaac Ssewanyana, Prasanna Jagannathan, Margaret E Feeney, Bryan Greenhouse, Sebasti...> ;Iscience. 2023 Dec 15
• Safety and efficacy of inhaled interferon-β1a (SNG001) in adults with mild-to-moderate COVID-19: a randomized, controlled, phase II trial.
  Prasanna Jagannathan, Kara W Chew, Mark J Giganti, Michael D Hughes, Carlee Moser, Mark J Main, Phillip D Monk, Arzhang Cyrus Javan, Jonathan Z Li, Courtney V Fletcher...> ;Eclinicalmedicine. 2023 Nov 1
• 1 citations
  Malaria-specific Type 1 regulatory T cells are more abundant in first pregnancies and associated with placental malaria.
  Adam S Kirosingh, Alea Delmastro, Abel Kakuru, Kattria van der Ploeg, Sanchita Bhattacharya, Kathleen D Press, Maureen Ty, Lauren de la Parte, Jimmy Kizza, Mary Muhind...> ;Ebiomedicine. 2023 Sep 1
• 1 citations
  The Tomato Brown Rugose Fruit Virus Movement Protein Gene Is a Novel Microbial Source Tracking Marker.
  Rezvani, A. R., Aravind Natarajan, Brayon J Fremin, Danica T Schmidtke, Marlene K Wolfe, Soumaya Zlitni, Katherine E Graham, Erin F Brooks, Christopher J Severyn, Kath...> ;Applied and Environmental Microbiology. 2023 Jul 26
• 136 citations
  Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection.
  Kumar, A. D., Carrithers, M. D., Carrithers, M. D., Elias, M., Altman, N. J., Chu, H. Y., Krieger, A., Radosta, J. M., Sabati, A. A., Tanayott Thaweethai, Sarah E Joll...> ;JAMA. 2023 Jun 13
• 17 citations
  Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC).
  Sindhu Mohandas, Prasanna Jagannathan, Timothy J Henrich, Zaki A Sherif, Christian Bime, Erin Quinlan, Michael A Portman, Marila Gennaro, Jalees Rehman> ;Elife. 2023 May 26
• 2 citations
  Impact of high human genetic diversity in Africa on immunogenicity and efficacy of RTS,S/AS01 vaccine.
  Stephen Tukwasibwe, Gerald Mboowa, Ivan Sserwadda, Joaniter I Nankabirwa, Emmanuel Arinaitwe, Isaac Ssewanyana, Yoweri Taremwa, Gerald Tumusiime, Moses R Kamya, Prasan...> ;Immunogenetics. 2023 Jun 1
• 12 citations
  Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8T cell responses post SARS-CoV-2 infection.
  Fei Gao, Vamsee Mallajosyula, Prabhu S Arunachalam, Kattria van der Ploeg, Monali Manohar, Katharina Röltgen, Fan Yang, Oliver Wirz, Ramona Hoh, Emily Haraguchi, Ji-Ye...> ;Immunity. 2023 Apr 11
• Can we reduce malaria in pregnancy and improve birth outcomes?
  Abel Kakuru, Prasanna Jagannathan> ;Lancet. 2023 Mar 25
• 6 citations
  Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.
  Amanda Fabra-García, Sophia Hailemariam, Roos M de Jong, Kirsten Janssen, Karina Teelen, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Danton Ivanochko, Anthony Sem...> ;Immunity. 2023 Feb 14
• 4 citations
  Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230.
  Danton Ivanochko, Amanda Fabra-García, Karina Teelen, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Jocelyn Newton, Anthony Semesi, Marloes de Bruijni, Judith Bolsc...> ;Immunity. 2023 Feb 14
• Challenges in Harnessing Shared Within-Host Severe Acute Respiratory Syndrome Coronavirus 2 Variation for Transmission Inference.
  Katharine S Walter, Eugene Kim, Renu Verma, Jonathan Altamirano, Sean Leary, Yuan J Carrington, Prasanna Jagannathan, Upinder Singh, Aruna Subramanian, Chaitan Khosla,...> ;Open Forum Infectious Diseases. 2023 Feb 1
• 6 citations
  Seroprevalence of Antibodies to SARS-CoV-2 in Rural Households in Eastern Uganda, 2020-2022.
  Jessica Briggs, Saki Takahashi, Patience Nayebare, Gloria Cuu, John Rek, Maato Zedi, Timothy Kizza, Emmanuel Arinaitwe, Joaniter I Nankabirwa, Moses Kamya, Prasanna Ja...> ;JAMA Network Open. 2023 Feb 1
• 9 citations
  Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria.
  Maureen Ty, Shenghuan Sun, Perri C Callaway, John Rek, Kathleen D Press, Kattria van der Ploeg, Jason Nideffer, Zicheng Hu, Sandy Klemm, William Greenleaf, Michele Don...> ;Science Translational Medicine. 2023 Jan 25
• 1 citations
  Tomato brown rugose fruit virus Mo gene is a novel microbial source tracking marker.
  Aravind Natarajan, Brayon J Fremin, Danica T Schmidtke, Marlene K Wolfe, Soumaya Zlitni, Katherine E Graham, Erin F Brooks, Christopher J Severyn, Kathleen M Sakamoto,...> ;Biorxiv. 2023 Jan 10
• 3 citations
  Metagenomic next-generation sequencing to characterize potential etiologies of non-malarial fever in a cohort living in a high malaria burden area of Uganda.
  Lusajo Mwakibete, Saki Takahashi, Vida Ahyong, Allison Black, John Rek, Isaac Ssewanyana, Moses Kamya, Grant Dorsey, Prasanna Jagannathan, Isabel Rodríguez-Barraquer, ...> ;PLOS Global Public Health. 2023 Jan 1
• Sex-Linked Differences in Malaria Risk Across the Lifespan.
  Jessica Briggs, Margaret Murray, Jason Nideffer, Prasanna Jagannathan> ;Current Topics in Microbiology and Immunology. 2023 Jan 1
• 7 citations
  Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.
  Chu, H. Y., Leora I Horwitz, Tanayott Thaweethai, Shari B Brosnahan, Mine S Cicek, Megan L Fitzgerald, Jason D Goldman, Rachel Hess, S L Hodder, Vanessa L Jacoby, Mich...> ;Plos One. 2023 Jan 1
• 23 citations
  Favipiravir for Treatment of Outpatients With Asymptomatic or Uncomplicated Coronavirus Disease 2019: A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial.
  Holubar, M., Subramanian, A., Purington, N., Hedlin, H., Bunning, B., Walter, K., Bonilla, H., Boumis, A., Chen, M., Clinton, K., Dewhurst, L., Epstein, C., Jagannatha...> ;Clinical Infectious Diseases. 2022 Nov 30
• 7 citations
  Early immune markers of clinical, virological, and immunological outcomes in patients with COVID-19: a multi-omics study.
  Zicheng Hu, Kattria van der Ploeg, Saborni Chakraborty, Prabhu S Arunachalam, Diego A M Mori, Karen B Jacobson, Hector Bonilla, Julie Parsonnet, Jason R Andrews, Maris...> ;Elife. 2022 Oct 14
• 2 citations
  Reconstructing the SARS-CoV-2 epidemic in eastern Uganda through longitudinal serosurveillance in a malaria cohort.
  Jessica Briggs, Saki Takahashi, Patience Nayebare, Gloria Cuu, John Rek, Maato Zedi, Timothy Kizza, Emmanuel Arinaitwe, Joaniter I Nankabirwa, Moses Kamya, Prasanna Ja...> ;Medrxiv. 2022 Sep 21
• 4 citations
  Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children.
  Jo-Anne Chan, Jessica R Loughland, Lauren de la Parte, Satomi Okano, Isaac Ssewanyana, Mayimuna Nalubega, Felistas Nankya, Kenneth Musinguzi, John Rek, Emmanuel Arinai...> ;Nature Communications. 2022 Jul 18
• 12 citations
  TNF-αCD4T cells dominate the SARS-CoV-2 specific T cell response in COVID-19 outpatients and are associated with durable antibodies.
  Kattria van der Ploeg, Adam S Kirosingh, Diego A M Mori, Saborni Chakraborty, Zicheng Hu, Benjamin L Sievers, Karen B Jacobson, Hector Bonilla, Julie Parsonnet, Jason ...> ;Cell Reports. Medicine. 2022 Jun 21
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Journal Articles

• Dihydroartemisinin-Piperaquine for Intermittent Preventive Treatment of Malaria During Pregnancy and Risk of Malaria in Early Childhood: A Randomized Controlled Trial  
  Bryan Greenhouse, Prasanna Jagannathan, Diane V Havlir, PLoS One