PratikSinhaMD

PubMed

• Rapidly improving ARDS differs clinically and biologically from persistent ARDS.
  Patricia L Valda Toro, Andrew Willmore, Nelson E Wu, Kevin L Delucchi, Alejandra Jauregui, Pratik Sinha, Kathleen D Liu, Carolyn M Hendrickson, Aartik Sarma, Lucile P ...> ;Critical Care. 2024 Apr 22
• 2 citations
  Individualized Treatment Effects of Oxygen Targets in Mechanically Ventilated Critically Ill Adults.
  Alexandra B Spicer, Emma J Graham Linck, Paul J Young, Kevin G Buell, Jonathan D Casey, Kevin P Seitz, Edward T Qian, Wesley H Self, Todd W Rice, Pratik Sinha, Matthew...> ;JAMA. 2024 Apr 9
• 3 citations
  Molecular Phenotypes of Acute Respiratory Distress Syndrome in the ROSE Trial Have Differential Outcomes and Gene Expression Patterns That Differ at Baseline and Longi...
  Pratik Sinha, Lucile Neyton, Aartik Sarma, Nelson Wu, Chayse Jones, Hanjing Zhuo, Kathleen D Liu, Estella Sanchez Guerrero, Rajani Ghale, Christina Love, Eran Mick, Ke...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Apr 1
• 3 citations
  Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes.
  Lucile P A Neyton, Pratik Sinha, Aartik Sarma, Eran Mick, Katrina Kalantar, Stephanie Chen, Nelson Wu, Kevin Delucchi, Hanjing Zhuo, Lieuwe D J Bos, Alejandra Jauregui...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Apr 1
• 1 citations
  Advancing specificity in delirium: The delirium subtyping initiative.
  Emily M L Bowman, Nathan E Brummel, Gideon A Caplan, Colm Cunningham, Lis A Evered, Kirsten M Fiest, Timothy D Girard, Thomas A Jackson, Sara C LaHue, Heidi L Lindroth...> ;Alzheimer's & Dementia. 2024 Jan 1
• 21 citations
  Ultrasensitive lateral-flow assays via plasmonically active antibody-conjugated fluorescent nanoparticles.
  Rohit Gupta, Prashant Gupta, Sean Wang, Artem Melnykov, Qisheng Jiang, Anushree Seth, Zheyu Wang, Jeremiah J Morrissey, Ige George, Sumanth Gandra, Gregory A Storch, B...> ;Nature Biomedical Engineering. 2023 Dec 1
• 2 citations
  Identification of molecular subphenotypes in two cohorts of paediatric ARDS.
  Nadir Yehya, Matt S Zinter, Jill M Thompson, Michelle J Lim, Mark R Hanudel, Mustafa F Alkhouli, Hector Wong, Matthew N Alder, Daniel J McKeone, E Scott Halstead, Prat...> ;Thorax. 2024 Jan 18
• 2 citations
  Leveraging Data Science and Novel Technologies to Develop and Implement Precision Medicine Strategies in Critical Care.
  Lazaro N Sanchez-Pinto, Sivasubramanium V Bhavani, Mihir R Atreya, Pratik Sinha> ;Critical Care Clinics. 2023 Oct 1
• 1 citations
  Elevated Plasma Interleukin-18 Identifies High-Risk Acute Respiratory Distress Syndrome Patients not Distinguished by Prior Latent Class Analyses Using Traditional Inf...
  Shaun M Pienkos, Pratik Sinha, Jiazhen Guan, Cecilia M O'Kane, Joseph E Levitt, Jennifer G Wilson, Manu Shankar-Hari, Michael A Matthay, Carolyn S Calfee, Rebecca M Ba...> ;Critical Care Medicine. 2023 Dec 1
• 10 citations
  Identifying molecular phenotypes in sepsis: an analysis of two prospective observational cohorts and secondary analysis of two randomised controlled trials.
  Pratik Sinha, V Eric Kerchberger, Andrew Willmore, Julia Chambers, Hanjing Zhuo, Jason Abbott, Chayse Jones, Nancy Wickersham, Nelson Wu, Lucile Neyton, Charles R Lang...> ;The Lancet. Respiratory Medicine. 2023 Nov 1
• 4 citations
  Estimating the attributable fraction of mortality from acute respiratory distress syndrome to inform enrichment in future randomised clinical trials.
  Rohit Saha, Tài Pham, Pratik Sinha, Manoj V Maddali, Giacomo Bellani, Eddy Fan, Charlotte Summers, Abdel Douiri, Gordon D Rubenfeld, Carolyn S Calfee, John Gerard Laff...> ;Thorax. 2023 Oct 1
• 6 citations
  Individualized Treatment Effects of Bougie versus Stylet for Tracheal Intubation in Critical Illness.
  Kevin P Seitz, Alexandra B Spicer, Jonathan D Casey, Kevin G Buell, Edward T Qian, Emma J Graham Linck, Brian E Driver, Wesley H Self, Adit A Ginde, Stacy A Trent, She...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Jun 15
• Are There Distinct Cardiovascular Subclasses in Acute Respiratory Distress Syndrome? Maybe.
  Patrick R Lawler, Sinha, P.> ;Critical Care Medicine. 2023 Apr 1
• 7 citations
  Plasma metabolic profiling implicates dysregulated lipid metabolism and glycolytic shift in hyperinflammatory ARDS.
  Narges Alipanah-Lechner, Lucile Neyton, Eran Mick, Andrew Willmore, Aleksandra Leligdowicz, Kévin Contrepois, Alejandra Jauregui, Hanjing Zhuo, Carolyn Hendrickson, An...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2023 Mar 1
• 23 citations
  Biological Phenotyping in Sepsis and Acute Respiratory Distress Syndrome.
  Nuala J Meyer, Carolyn S Calfee, Sinha, P.> ;Annual Review of Medicine. 2023 Jan 27
• 2 citations
  Multistate Modeling of Clinical Trajectories and Outcomes in the ICU: A Proof-of-Concept Evaluation of Acute Kidney Injury Among Critically Ill Patients With COVID-19.
  Patrick G Lyons, Aaloke Mody, Alice F Bewley, Morgan Schoer, Bharat Neelam Raju, Elvin Geng, Philip R O Payne, Anitha Vijayan, Sinha, P.> ;Critical Care Explorations. 2022 Dec 1
• 19 citations
  Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults.
  Katrina L Kalantar, Lucile Neyton, Mazin Abdelghany, Eran Mick, Alejandra Jauregui, Saharai Caldera, Paula Hayakawa Serpa, Rajani Ghale, Jack Albright, Aartik Sarma, A...> ;Nature Microbiology. 2022 Nov 1
• 5 citations
  Hospital trajectories and early predictors of clinical outcomes differ between SARS-CoV-2 and influenza pneumonia.
  Patrick G Lyons, Sivasubramanium V Bhavani, Aaloke Mody, Alice Bewley, Katherine Dittman, Aisling Doyle, Samuel L Windham, Tej M Patel, Bharat Neelam Raju, Matthew Kel...> ;Ebiomedicine. 2022 Nov 1
• 4 citations
  The prognostic value of early measures of the ventilatory ratio in the ARDS ROSE trial.
  Ana Carolina Costa Monteiro, Sitaram Vangala, Katherine D Wick, Kevin L Delucchi, Emily R Siegel, B Taylor Thompson, Kathleen D Liu, Anil Sapru, Michael A Matthay, , P...> ;Critical Care. 2022 Sep 29
• 11 citations
  Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19.
  Wick, K., Leligdowicz, A., Willmore, A., Carrillo, S., Ghale, R., Jauregui, A., Chak, S., Nguyen, V., Lee, D., Jones, C., Dewar, R., Lane, H., Kangelaris, K., Hendrick...> ;Critical Care. 2022 Sep 14
• 13 citations
  Opportunities for improved clinical trial designs in acute respiratory distress syndrome.
  Katherine D Wick, Neil R Aggarwal, Martha A Q Curley, Alpha A Fowler 3rd, Samir Jaber, Maciej Kostrubiec, Nathalie Lassau, Pierre François Laterre, Guillaume Lebreton,...> ;The Lancet. Respiratory Medicine. 2022 Sep 1
• 3 citations
  Ventilatory Ratio Is a Valuable Prognostic Indicator in an Observational Cohort of Patients With ARDS.
  Emily R Siegel, Hanjing Zhuo, Alexander I Papolos, Siyuan A Ni, Kathryn Vessel, Annika Belzer, Emily B Minus, Carolyn S Calfee, Michael A Matthay, Katherine D Wick, Si...> ;Respiratory Care. 2022 Sep 1
• 7 citations
  Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis.
  Maddali, M., Churpek, M., Pham, T., Rezoagli, E., Zhuo, H., Zhao, W., He, J., Delucchi, K., Wang, C., Wickersham, N., McNeil, J., Jauregui, A., Ke, S., Vessel, K., Gom...> ;The Lancet. Respiratory Medicine. 2022 Apr 1
• 25 citations
  Towards a biological definition of ARDS: are treatable traits the solution?
  Lieuwe D J Bos, John G Laffey, Lorraine B Ware, Nanon F L Heijnen, Brijesh Patel, Matthieu Jabaudon, Julie A Bastarache, Daniel F McAuley, Charlotte Summers, Carolyn S...> ;Intensive Care Medicine Experimental. 2022 Mar 11
• 38 citations
  Identification of phenotypes in paediatric patients with acute respiratory distress syndrome: a latent class analysis.
  Mary K Dahmer, Guangyu Yang, Min Zhang, Michael W Quasney, Anil Sapru, Heidi M Weeks, Martha A Q Curley, Kevin L Delucchi, Carolyn S Calfee, Heidi Flori, , , Sinha, P.> ;The Lancet. Respiratory Medicine. 2022 Mar 1
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