Overview of Dr. Thaker
I am an Associate Professor in the Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University in St. Louis, Missouri as well as a Clinician and a Research Member at the Siteman Cancer Center of Washington University. I trained as a cancer biologist during my fellowship at MD Anderson Cancer Center with emphasis in cell and molecular biology including angiogenesis and invasion in ovarian cancer. Now I am interested in novel therapeutics in all gynecologic cancers and have led national as well as institutional clinical trials in ovarian, cervical, and endometrial malignancies. Currently, I run our Division’s clinical trial research efforts.
Office
4921 Parkview Pl
Saint Louis, MO 63110Fax+1 866-282-1113- Is this information wrong?
Education & Training
- University of Texas M D Anderson Cancer CenterFellowship, Gynecologic Oncology, 2006
- University of TexasMS, Cancer Biology, 2004
- University of Pennsylvania Health SystemResidency, Obstetrics and Gynecology, 1999 - 2002
- Drexel University College of Medicine/Hahnemann University HospitalResidency, Obstetrics and Gynecology, 1997 - 1999
- MCP-Hahnemann College of MedicineClass of 1997, MD
- Villanova UniversityBA, Biology, 1995
Certifications & Licensure
- MO State Medical License 2006 - 2024
- IL State Medical License 2020 - 2023
- TX State Medical License 2003 - 2016
- PA State Medical License 1998 - 2012
- American Board of Obstetrics and Gynecology Obstetrics & Gynecology
- American Board of Obstetrics and Gynecology Gynecologic Oncology
Awards, Honors, & Recognition
- Outstanding Publication Award for 2016 of an NRG Oncology Publication on cervical cancer in Annals of Oncology 2017
- Certificate of Excellence in Reviewing Editors of Gynecologic Oncology and Gynecologic Oncology Case Reports, 2014
- CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012
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Clinical Trials
- A Phase I Study of Bi-Weekly rBBX-01 in Patients With Solid Tumors Start of enrollment: 2008 Oct 01
- Biobehavioral-Cytokine Interactions in Ovarian Cancer Start of enrollment: 2003 Aug 01
- Therapeutic Targeting of Stress Factors in Ovarian Cancer Patients Start of enrollment: 2010 Aug 01
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Publications & Presentations
PubMed
- Real-world Outcomes Associated With Poly(ADP-ribose) Polymerase Inhibitor Monotherapy Maintenance in Patients With Primary Advanced Ovarian Cancer.John K Chan, Jinan Liu, Jinlin Song, Cheryl Xiang, Eric Wu, Linda Kalilani, Jean A Hurteau, Premal H Thaker> ;American Journal of Clinical Oncology. 2023 Apr 28
- RAD51 foci as a biomarker predictive of platinum chemotherapy response in ovarian cancer.Amanda J Compadre, Lillian N van Biljon, Mark C Valentine, Alba Llop-Guevara, Emily Graham, Bisiayo Fashemi, Andrea Herencia-Ropero, Emilee N Kotnik, Isaac Cooper, Sha...> ;Clinical Cancer Research. 2023 Apr 25
- HER2+ endometrioid endometrial cancer possesses distinct molecular and immunologic features associated with a more active immune microenvironment and worse prognosis.Shaina F Bruce, Sharon Wu, Jennifer R Ribeiro, Alex Farrell, Matthew J Oberley, Ira Winer, Britt K Erickson, Tenley Klc, Nathaniel L Jones, Premal H Thaker, Matthew A ...> ;Gynecologic Oncology. 2023 May 1
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Journal Articles
- Modified Frailty Index Is Predictive of Wound Complications in Obese Patients Undergoing Gynecologic Surgery via a Midline Vertical IncisionPremal Thaker, MD, Gynecologic Oncology
- Life Stress as a Risk Factor for Sustained Anxiety and Cortisol Dysregulation During the First Year of Survivorship in Ovarian CancerAnil K Sood, Premal H Thaker, Laila Dahmoush, Cancer
- Therapeutic Inhibition of the Receptor Tyrosine Kinase AXL Improves Sensitivity to Platinum and Taxane in Ovarian CancerIan S Hagemann, Premal H Thaker, Carolyn K McCourt, Katherine C Fuh, David G Mutch, Andrea R Hagemann, Matthew A Powell, Clinical Cancer Research
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Press Mentions
- Novel Immunotherapeutic Agent Shows Benefit in Ovarian CancerAugust 10th, 2015
- Celsion's GEN-1 Immunotherapy Highlighted in Oppenheimer's Expert Call on Ovarian Cancer Treatment Landscape and Emerging OpportunitiesAugust 9th, 2019
- Afternoons on 11: Spotlight on Ovarian CancerApril 4th, 2016
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Committees
- Member, Ovarian Committee, NRG Oncolgoy Group 2011 - 2018
- Member, Phase I Committee, NRG Oncology Group 2007 - 2018
Research History
- Biobehavioral Influences on Ovarian Cancer Progression: Role of Chemoresistance2016 - 2020
- Leading Academic Participating SitesThe goal of this project is to improve patient accrual to clinical trials at NCI designated cancer centers.2014 - 2019
- Gynecologic Oncology Support fundThe goal of the project is to support research in ovarian cancer targeting the identification of clinically relevant targets in ovarian cancer.2017 - 2018
- Molecular Oncology Training GrantI serve as a clinical mentor to Ph.D. students in order for them to better understand how to translate bench findings in clinical problems.2005 - 2018
Professional Memberships
- Fellow
Hospital Affiliations
- Siteman Cancer CenterSaint Louis, Missouri
- Barnes-Jewish HospitalSaint Louis, Missouri
- Missouri Baptist Sullivan HospitalSullivan, Missouri
- Missouri Baptist Medical CenterSaint Louis, Missouri
- St. Louis Children's HospitalSaint Louis, Missouri
- Barnes-Jewish West County HospitalSaint Louis, Missouri
- Progress West HospitalO Fallon, Missouri
Insurance Accepted
- Aetna Choice POS II
Aetna HMO
Anthem Blue Access Choice PPO
Anthem Blue Access PPO
BCBS Blue Card PPO
BCBS Illinois PPO
CIGNA HMO
CIGNA Open Access
CIGNA PPO
Coventry Health Care PPO PlatinumCoventry Missouri - HMO/POS
First Health PPO
Great West PPO
HealthLink PPO
Humana ChoiceCare Network PPO
Multiplan PHCS PPO
Multiplan PPO
United Healthcare - Direct Choice Plus POS
United Healthcare - Direct Options PPO - Please verify your coverage with the provider's office directly when scheduling an appointment
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