Punam Malik MD
Professor, Pediatrics, University of Cincinnati College of Medicine
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3333 Burnet Ave# 7015Cincinnati, OH 45229
Phone+1 513-636-4266
Fax+1 513-636-3549
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Education & Training
Children's Hospital Los AngelesFellowship, Pediatric Hematology/Oncology, 1991 - 1996
Lady Hardinge Medical CollegeClass of 1988
Certifications & Licensure
OH State Medical License 2008 - 2026
CA State Medical License 1996 - 2024
IN State Medical License 2022 - 2023
KY State Medical License 2022 - 2022
American Board of Pediatrics Pediatrics- American Board of Pediatrics Pediatric Hematology-Oncology
Clinical Trials
- Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy Start of enrollment: 2005 Dec 01
- Role of Placenta Growth Factor in Sickle Acute Chest Syndrome Start of enrollment: 2007 Mar 01
- Trial of Zileuton CR in Children and Adults With Sickle Cell Disease Start of enrollment: 2010 Sep 01
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Publications & Presentations
PubMed
- Preclinical efficacy of a modified gamma-globin lentivirus gene therapy in Berkeley sickle cell anemia mice and human xenograft models.Archana Shrestha, Devin M Pillis, Sydney Felker, Mengna Chi, Kimberly Wagner
Molecular Therapy. Methods & Clinical Development. 2025-06-12 - An engineered β-globin homology donor reveals insights into β-globin expression and betters HDR.Mengna Chi, Punam Malik
Molecular Therapy. 2025-04-02 - 3 citationsNRASmutation drives elevated angiopoietin-2 expression in human endothelial cells and a genetic mouse model.Patricia Pastura, C Griffin McDaniel, Sara Alharbi, Dermot Fox, Bethany Coleman
Pediatric Blood & Cancer. 2024-07-01
Abstracts/Posters
- Phase 1 Single (SAD) and Multiple Ascending Dose (MAD) Studies of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of FT-4202, an Allosteric A...Punam Malik, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Progression of Albuminuria in Sickle Cell Anemia: A Multicenter, Longitudinal StudyPunam Malik, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Lectures
- Friday Scientific Workshop on Novel Curative Options: Gene-Editing and Gene Therapy for Hemoglobinopathies with a Focus on Sickle Cell Disease61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
- Disease Modification in Sickle Cell Disease: Mechanisms, Advances and Clinical Implications61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
Press Mentions
3 Signs of Progress Against Sickle Cell DiseaseJune 19th, 2019- Early Clinical Trial Data Show Gene Therapy Reversing Sickle Cell AnemiaDecember 3rd, 2018
Ramaswamy's Latest 'Vant' to Focus on Gene Therapies for Blood DisordersNovember 26th, 2018- Join now to see all
Grant Support
- Mechanisms underlying increased risk of hematological malignancy in sickle cell disease.CINCINNATI CHILDRENS HOSP MED CTR2025–2027
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