R. Mark Richardson MD PhD
Epilepsy Surgery, Stereotactic & Functional Neurosurgery
Director of Functional Neurosurgery, Massachusetts General Hospital Harvard Medical School
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55 Fruit St# GRAY502Boston, MA 02114
Phone+1 617-726-8581
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Summary
- Dr. Richardson completed the MD-PhD program at Virginia Commonwealth University’s Medical College of Virginia and neurosurgical residency at the University of California, San Francisco. His clinical expertise includes both awake and asleep DBS for movement disorders, psychiatric indications, and epilepsy, awake brain mapping, robotic-assisted surgery for both stereo-EEG and DBS implantation, and Responsive Neurostimulation for epilepsy. Prior to joining Mass General, Dr. Richardson was Director of the Epilepsy and Movement Disorders Surgery Program at the University of Pittsburgh Medical Center (UPMC). There, he established one of the world's leading intraoperative-MRI functional neurosurgery programs, encompassing DBS for movement disorders, gene therapy clinical trials for Parkinson’s disease, and laser thermal ablation for epilepsy, work which now continues at MGH.
Dr. Richardson is recognized internationally for his work, having published numerous related papers and book chapters, and frequently speaking at national and international meetings. He is a member of the Executive Board of the American Society for Stereotactic and Functional Neurosurgery.
Dr. Richardson also is a neuroscientist who founded the Brain Modulation Lab, which conducts human systems neuroscience research using intracranial recording and stimulation.
Education & Training
University of California (San Francisco)Residency, Neurological Surgery, 2005 - 2011
Medical College of VirginiaPhD, 1999 - 2005
Virginia Commonwealth University School of MedicineClass of 2005- Medical College of VirginiaMSc, Physiology, 1997 - 1999
- University of VirginiaB.A., Environmental Sciences, 1993 - 1997
Certifications & Licensure
MA State Medical License 2019 - 2028
ME State Medical License 2024 - 2027
NH State Medical License 2023 - 2027
CT State Medical License 2023 - 2026
VT State Medical License 2023 - 2026
PA State Medical License 2011 - 2021
CA State Medical License 2006 - 2011
American Board of Neurological Surgery Neurological Surgery
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2013-2017
- CMS Meaningful Use Stage 1 Certification dbMotion, dbMotion Inc., 2013-2017
- CMS Meaningful Use Stage 2 Certification MyUPMC, UPMC, 2013-2017
Clinical Trials
- Safety and Efficacy Study of VY-AADC01 for Advanced Parkinson's Disease Start of enrollment: 2017 May 11
- VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1) Start of enrollment: 2018 Oct 17
- Deep Neural Network Approaches for Closed-Loop Deep Brain Stimulation Start of enrollment: 2021 Jun 10
Publications & Presentations
PubMed
- Clinical trial barriers in neurostimulation for pediatric drug-resistant epilepsy.Mira C Hasner, Faith C Robertson, Nathaniel D Sisterson, Gabriel Lazaro-Munoz, Florence T Bourgeois
Epileptic Disorders. 2026-09-10 - Opportunities for advancing paediatric medical device access: regulatory frameworks in the EU and USA.Mira C Hasner, Iris P van Mullem, Faith C Robertson, Florence T Bourgeois, R Mark Richardson
The Lancet. Child & Adolescent Health. 2026-09-08 - Real-world outcomes of responsive neurostimulation in patients with Lennox-Gastaut syndrome: A multicenter retrospective study.Shanna M Swartwood, Robert J Bollo, Catherine J Chu, Alexandra L Geffrey, Robert Mark Richardson
Epilepsia Open. 2026-08-01
Journal Articles
- Dynamics of human subthalamic neuron phase-locking to motor and sensory cortical oscillations during movementLipski WJ, Wozny TA, Alhourani A, Kondylis E, Turner RS, Crammond DJ, Richardson RM, J Neurophysiol, 1/7/2017
- Effects of hippocampal low-frequency stimulation in idiopathic non-human primate epilepsy assessed via a remote-sensing-enabled neurostimulatorWozny TA, Lipski WJ, Alhourani A, Kondylis ED, Antony A, Richardson RM, Exp Neurol, 1/7/2017
- Global Brain InitiativesRichardson RM, Neurosurgery, 1/1/2017
Books/Book Chapters
Abstracts/Posters
- Amplified Movement-Related Cortical Desynchronization and Decoupling Allow Normal Motor Responses in Patients with Parkinson's Disease and Essential Tremor.Richardson RM, Society for Neuroscience Annual Meeting, Chicago, IL, 1/1/2015
- Movement Modulates Phase-Locking Between Neuronal Discharge in Human STN and Cortical Oscillations.Richardson RM, Society for Neuroscience Annual Meeting, Chicago, IL, 1/1/2015
- Subthalamic Deep Brain Stimulation Decreases the Extent of Cortical Movement-Related Beta Desynchronization In Parkinson's Disease: A Magnetoencephalography Study.Richardson RM, Society for Neuroscience Annual Meeting,, Chicago, IL, 1/1/2015
Lectures
- Subthalamic and Cortico-subthalamic Participation in Speech ProductionPalo Alto, CA - 1/1/2017
- Hippocampal Functional Connectivity Disruption in Mesial Temporal Lobe Epilepsy Captured Using Magnetoencephalography.Chicago, IL - 1/2/2016
- Cortical-Basal Ganglia Loop Interactions During Movement Revealed Through Intracranial Recordings in Parkinson's Disease Subjects.Chicago, IL - 1/2/2016
Grant Support
- Targeting pathologic spike-ripples to isolate and disrupt epileptic dynamicsNINDS2021–2026
- Cortical-Basal Ganglia Speech NetworksNINDS2021–2026
- Predoctoral National Research Service AwardNINDS2001–2004
Research History
- Director, Brain Modulation LabThe Brain Modulation Lab studies human systems neurophysiology in the course of treating epilepsy and movement disorders.2011 - Present
- Postdoctoral Research FellowBankiewicz Laboratory, University of California San Francisco2009 - 2010
Professional Memberships
- Fellow
- Member
- Member
- American Association of Stereotactic and Functional NeurosurgeryExecutive Committee
External Links
- MGH Profilehttps://www.massgeneral.org/doctors/20630/mark-richardson
- Brain Modulation Labhttp://www.brainmodulationlab.org
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