RaajitRampalMD

PubMed

• Mixed histiocytic neoplasms: A multicentre series revealing diverse somatic mutations and responses to targeted therapy.
  Joshua S Friedman, Benjamin H Durham, Anne S Reiner, Mariko Yabe, Kseniya Petrova-Drus, Ahmet Dogan, Melissa Pulitzer, Klaus J Busam, Jasmine H Francis, Raajit K Rampa...> ;British Journal of Haematology. 2024 Apr 12
• to: Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia.
  Ruben Mesa, Jean-Jacques Kiladjian, Claire N Harrison, Stephen T Oh, Alessandro M Vannucchi, Sarah A Buckley, Adam R Craig, Karisse Roman-Torres, John O Mascarenhas, S...> ;Haematologica. 2024 Apr 1
• Phase 2 study of add-on parsaclisib for patients with myelofibrosis and suboptimal response to ruxolitinib: final results.
  Abdulraheem Yacoub, Uma Borate, Raajit K Rampal, Haris Ali, Eunice S Wang, Aaron T Gerds, Gabriela Hobbs, Marina Kremyanskaya, Elliott Winton, Casey O'Connell, Swati G...> ;Blood Advances. 2024 Mar 26
• Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies.
  Krystel-Whittemore, M., Petrova-Drus, K., Ptashkin, R., Ewalt, M., Yao, J., Liu, Y., Zhu, M., Benhamida, J., Durham, B., Kumar, J., Nafa, K., Kiecka, I., Bowman, A., G...> ;Haematologica. 2024 Mar 7
• Treatment of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN): focus on the use of tagraxofusp and clinical considerations.
  Rizzieri, D., Pemmaraju, N., Madanat, Y., Fazal, S., Rampal, R., Mannis, G., Wang, E., Foran, J., Lane, A., Fazal, S.> ;Leukemia & Lymphoma. 2024 Feb 23
• Interferons in the treatment of myeloproliferative neoplasms.
  Pankit Vachhani, John Mascarenhas, Prithviraj Bose, Gabriela Hobbs, Abdulraheem Yacoub, Jeanne M Palmer, Aaron T Gerds, Lucia Masarova, Andrew T Kuykendall, Raajit K R...> ;Therapeutic Advances in Hematology. 2024 Jan 1
• Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing.
  Ryan N Ptashkin, Mark D Ewalt, Gowtham Jayakumaran, Iwona Kiecka, Anita S Bowman, JinJuan Yao, Jacklyn Casanova, Yun-Te David Lin, Kseniya Petrova-Drus, Abhinita S Moh...> ;Nature Communications. 2023 Oct 28
• 2 citations
  Moving toward disease modification in polycythemia vera.
  Jan Philipp Bewersdorf, Joan How, Lucia Masarova, Prithviraj Bose, Naveen Pemmaraju, John Mascarenhas, Raajit K Rampal> ;Blood. 2023 Nov 30
• Prospective analysis to determine barriers to allogeneic hematopoietic cell transplantation in patients with acute leukemia.
  Karthik Nath, Jasme Lee, Theresa A Elko, Lauren Levy, Elaina Preston, Sean M Devlin, Doris M Ponce, Richard J Lin, Brian C Shaffer, Christina Cho, Ioannis Politikos, A...> ;American Journal of Hematology. 2023 Dec 1
• IDH1/2 inhibitor monotherapy in blast-phase myeloproliferative neoplasms: A multicentre experience.
  Naseema Gangat, Helen Ajufo, Maymona Abdelmagid, Omer Karrar, Kristen McCullough, Talha Badar, James Foran, Jeanne Palmer, Hassan Alkhateeb, Abhishek Mangaonkar, Andre...> ;British Journal of Haematology. 2023 Nov 1
• Matching-adjusted indirect comparison of the pelabresib-ruxolitinib combination vs JAKi monotherapy in myelofibrosis.
  Vikas Gupta, John Mascarenhas, Marina Kremyanskaya, Raajit K Rampal, Moshe Talpaz, Jean-Jacques Kiladjian, Alessandro M Vannucchi, Srdan Verstovsek, Gozde Colak, Debar...> ;Blood Advances. 2023 Sep 26
• 1 citations
  A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis.
  John Mascarenhas, Anna Rita Migliaccio, Heidi Kosiorek, Rupali Bhave, Jeanne Palmer, Andrew Kuykendall, Ruben Mesa, Raajit K Rampal, Aaron T Gerds, Abdulraheem Yacoub,...> ;Clinical Cancer Research. 2023 Sep 15
• 5 citations
  Outcomes after interruption of targeted therapy in patients with histiocytic neoplasms.
  Anne S Reiner, Benjamin H Durham, Mariko Yabe, Kseniya Petrova-Drus, Jasmine H Francis, Raajit K Rampal, Mario E Lacouture, Veronica Rotemberg, Omar Abdel-Wahab, Kathe...> ;British Journal of Haematology. 2023 Nov 1
• 5 citations
  Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia.
  Joseph G W McCarter, David Nemirovsky, Christopher A Famulare, Noushin Farnoud, Abhinita S Mohanty, Zoe S Stone-Molloy, Jordan Chervin, Brian J Ball, Zachary D Epstein...> ;Blood Advances. 2023 Sep 12
• 6 citations
  Ten years after ruxolitinib approval for myelofibrosis: a review of clinical efficacy.
  Naveen Pemmaraju, Prithviraj Bose, Raajit Rampal, Aaron T Gerds, Angela Fleischman, Srdan Verstovsek> ;Leukemia & Lymphoma. 2023 Jun 1
• 14 citations
  MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis.
  John Mascarenhas, Marina Kremyanskaya, Andrea Patriarca, Francesca Palandri, Timothy Devos, Francesco Passamonti, Raajit K Rampal, Adam J Mead, Gabriella Hobbs, Joseph...> ;Journal of Clinical Oncology. 2023 Nov 10
• 6 citations
  CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis.
  Andrew J Dunbar, Dongjoo Kim, Min Lu, Mirko Farina, Robert L Bowman, Julie L Yang, Young Park, Abdul Karzai, Wenbin Xiao, Zach Zaroogian, Kavi O'Connor, Shoron Mowla, ...> ;Blood. 2023 May 18
• 1 citations
  Treating accelerated and blast phase myeloproliferative neoplasms: progress and challenges.
  Helen O Ajufo, Julian A Waksal, John O Mascarenhas, Raajit K Rampal> ;Therapeutic Advances in Hematology. 2023 Jan 1
• 2 citations
  Hitting the brakes on accelerated and blast-phase myeloproliferative neoplasms: current and emerging concepts.
  Jan Philipp Bewersdorf, Raajit K Rampal> ;Hematology. American Society of Hematology. Education Program. 2022 Dec 9
• 15 citations
  Biological drivers of clinical phenotype in myelofibrosis.
  John Mascarenhas, Hélène F E Gleitz, Helen T Chifotides, Claire N Harrison, Srdan Verstovsek, Alessandro Maria Vannucchi, Raajit K Rampal, Jean-Jacques Kiladjian, Will...> ;Leukemia. 2023 Feb 1
• 12 citations
  North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: position on standards of care and areas of need.
  Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice Wang, Jayastu Senapati, Nathaniel R Wilson, Marina Konopleva, Arthur E Frankel, Vikas Gupta, Ruben Mesa, Matth...> ;Blood. 2023 Feb 9
• 1 citations
  MPN-379 Matching-Adjusted Indirect Comparison (MAIC) of Pelabresib (CPI-0610) in Combination With Ruxolitinib vs. JAK Inhibitor Monotherapy in Patients With Intermedia...
  Vikas Gupta, John Mascarenhas, Marina Kremyanskaya, Raajit K Rampal, Moshe Talpaz, Jean-Jacques Kiladjian, Alessandro Vannucchi, Srdan Verstovsek, Gozde Colak, Debarsh...> ;Clinical Lymphoma, Myeloma & Leukemia. 2022 Oct 1
• 4 citations
  MPN-375 BET Inhibitor Pelabresib (CPI-0610) Combined With Ruxolitinib in Patients With Myelofibrosis - JAK Inhibitor-Naïe or With Suboptimal Response to Ruxolitinib - ...
  John Mascarenhas, Marina Kremyanskaya, Andrea Patriarca, Claire Harrison, Prithviraj Bose, Raajit K Rampal, Francesca Palandri, Timothy Devos, Francesco Passamonti, Ga...> ;Clinical Lymphoma, Myeloma & Leukemia. 2022 Oct 1
• MPN-075 Efficacy and Safety of Add-on Parsaclisib to Ruxolitinib Therapy in Myelofibrosis Patients With Low Versus Higher Baseline Platelet Counts: A Subgroup Analysis...
  Abdulraheem Yacoub, Uma Borate, Raajit Rampal, Haris Ali, Eunice Wang, Aaron Gerds, Gabriela Hobbs, Marina Kremyanskaya, Elliott Winton, Casey O'Connell, Swati Goel, S...> ;Clinical Lymphoma, Myeloma & Leukemia. 2022 Oct 1
• 3 citations
  Epo-IGF1R cross talk expands stress-specific progenitors in regenerative erythropoiesis and myeloproliferative neoplasm.
  Hsi-Hsien Hsieh, Huiyu Yao, Yue Ma, Yuannyu Zhang, Xue Xiao, Helen Stephens, Naureen Wajahat, Stephen S Chung, Lin Xu, Jian Xu, Raajit K Rampal, Lily Jun-Shen Huang> ;Blood. 2022 Dec 1
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Journal Articles

• Efficacy of MEK Inhibition in Patients with Histiocytic Neoplasms  
  Robert J Young, Mario Lacouture, Neal Rosen, David M Hyman, Raajit Rampal, Gary A Ulaner, Benjamin H Durham, Lynn A Brody, Nature
• Genetic and Epigenetic Evolution as a Contributor to WT1-Mutant Leukemogenesis  
  Raajit Rampal, Ross L Levine, Benjamin H Durham, Blood
• Jak2V617F and Dnmt3a Loss Cooperate to Induce Myelofibrosis Through Activated Enhancer-Driven Inflammation  
  Raajit Rampal, MD, Blood

Abstracts/Posters

• Expansion of Prior Existing TP53 Mutated Clones in Polycythemia Vera Patients Treated with Idasanutlin
  Raajit K. Rampal, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• The Genetic Architecture of Myeloproliferative Neoplasms-Blast Phase (MPN-BP) Stem Cells
  Raajit K. Rampal, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Significance of Abnormalities of PPM1D in Myeloproliferative Neoplasms
  Raajit K. Rampal, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Timing for Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Chronic Myelomonocytic Leukemia (CMML): A Joint Study from the International MDS/MPN Working Gr...
  Raajit K. Rampal, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Landscape of TP53 Mutations in MPN
  Raajit K. Rampal, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Final Results of Prospective Treatment with Pegylated Interferon Alfa-2a for Patients with Polycythemia Vera and Essential Thrombocythemia in First and Second-Line Set...
  Raajit K. Rampal, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Dual Driver Mutant BCR-ABL1-Negative Myeloid Neoplasms: Multicenter Clinicopathologic and Genomic Analysis
  Rajit K. Rampal, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Identifying Cytokine Biomarkers of Response to Pegylated-Interferon Therapy in Polycythemia Vera and Essential Thrombocythemia: Correlative Analysis from the MPN-RC 11...
  Raajit K. Rampal, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Evaluation of Tagraxofusp (SL-401) Alone and in Combination with Ruxolitinib for the Treatment of Myeloproliferative Neoplasms
  Raajit K. Rampal, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
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Lectures

• Safety and Efficacy of Combined Ruxolitinib and Thalidomide in Patients with Myelofibrosis: A Phase II Study 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Approaches to the Individualized Management of MPNs: Best Practices and Guidance to Optimize Care 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Hematologic Malignancies Arising in Patients with Germ Cell Tumors: Secondary Somatic Differentiation of Hematopoietic Malignancies from Germ Cell Precursors 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• A Novel Prognostic Model Including Cytogenetic and Molecular Data in Patients with Primary and Post-Essential Thrombocythemia (ET)/Polycythemia Vera (PV) Myelofibrosis... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Prognostic Impact of Activating Mutations of the NRAS/KRAS Genes in Patients with Primary and Post-Essential Thrombocythemia (ET)/Polycythemia Vera (PV) Myelofibrosis ... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Evaluation of Combination Tagraxofusp (SL-401) and Hypomethylating Agent (HMA) Therapy for the Treatment of Chronic Myelomonocytic Leukemia (CMML) 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Selinexor, a First-in-Class XPO1 Inhibitor, Is Efficacious and Tolerable in Patients with Myelodysplastic Syndromes Refractory to Hypomethylating Agents 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Myeloproliferative Neoplasm (MPN) Blastic Transformation Occurs at the Level of Hematopoietic Stem Cells 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
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