RafaelSantana DavilaMD

PubMed

• Molecular phenotyping of small cell lung cancer using targeted cfDNA profiling of transcriptional regulatory regions.
  Joseph B Hiatt, Anna-Lisa Doebley, Henry U Arnold, Mohamed Adil, Holly Sandborg, Thomas W Persse, Minjeong Ko, Feinan Wu, Alvaro Quintanal Villalonga, Rafael Santana-D...> ;Science Advances. 2024 Apr 12
• 7 citations
  Performance status (PS) as a predictor of poor response to immune checkpoint inhibitors (ICI) in recurrent/metastatic head and neck cancer (RMHNSCC) patients.
  Cameron Chalker, Jenna M Voutsinas, Qian Vicky Wu, Rafael Santana-Davila, Victoria Hwang, Christina S Baik, Sylvia Lee, Brittany Barber, Neal D Futran, Jeffrey J Hoult...> ;Cancer Medicine. 2022 Nov 1
• 1 citations
  Chemo and Immuno-Therapeutic Options for Nonsmall Cell Lung Cancer Lung Cancer.
  Rafael Santana-Davila> ;The Surgical Clinics of North America. 2022 Jun 1
• 119 citations
  Small Cell Lung Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
  Apar Kishor P Ganti, Billy W Loo, Michael Bassetti, Collin Blakely, Anne Chiang, Thomas A D'Amico, Christopher D'Avella, Afshin Dowlati, Robert J Downey, Martin Edelma...> ;Journal of the National Comprehensive Cancer Network. 2021 Dec 1
• High End-of-Life Health Care Utilization in a Contemporary Cohort of Head and Neck Cancer Patients Treated with Immune Checkpoint Inhibitors.
  Cameron Chalker, Rafael Santana-Davila, Jenna M. Voutsinas, Qian Vicky Wu, Victoria Hwang, Christina S. Baik, Sylvia Lee, Brittany Barber, Neal D. Futran, Jeffrey J. H...> ;Journal of Palliative Medicine. 2021 Nov 30
• 2 citations
  Prognostic Value of Early Fluorodeoxyglucose-Positron Emission Tomography Response Imaging and Peripheral Immunologic Biomarkers: Substudy of a Phase II Trial of Risk-...
  Stephen R Bowen, Daniel S Hippe, Hannah M Thomas, Balukrishna Sasidharan, Paul D Lampe, Christina S Baik, Keith D Eaton, Sylvia Lee, Renato G Martins, Rafael Santana-D...> ;Advances in Radiation Oncology. 2021 Nov 21
• 40 citations
  Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumours (ASPEN-01): a first-in-human, open-label, multicentre, ph...
  Nehal Lakhani, Laura Q.M. Chow, Justin F. Gainor, Patricia LoRusso, Keun-Wook Lee, Hyun Cheol Chung, Jeeyun Lee, Yung-Jue Bang, F.S. Hodi, Won Seog Kim, Rafael Santana...> ;The Lancet. Oncology. 2021 Nov 15
• 50 citations
  Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial.
  Patrick M. Forde, Valsamo Anagnostou, Z. Sun, Suzanne E. Dahlberg, Hedy L. Kindler, Noushin Niknafs, Thomas Purcell, Rafael Santana-Davila, Arkadiusz Z. Dudek, Hossein...> ;Nature Medicine. 2021 Nov 8
• 42 citations
  Addition of Metformin to Concurrent Chemoradiation in Patients With Locally Advanced Non-Small Cell Lung Cancer: The NRG-LU001 Phase 2 Randomized Clinical Trial
  Heath D. Skinner, Chen Hu, Theodoros Tsakiridis, Rafael Santana-Davila, Bo Lu, Jeremy J. Erasmus, Anthony Doemer, Gregory M.M. Videtic, James Coster, Alex Xuezhong Yan...> ;JAMA Oncology. 2021 Sep 1
• A Phase II study of nab-Paclitaxel (nab-P) in patients with advanced non-small cell lung cancer with EGFR mutations after frontline tyrosine kinase inhibitor therapy.
  Christina S. Baik, Sylvia Lee, Kitty Cook, Sarah G. Wallace, Rebecca Wood, Rafael Santana-Davila, Laura Q.M. Chow, Cristina P. Rodriguez, Keith D. Eaton, Renato G. Mar...> ;Cancer Treatment and Research Communications. 2021 Jan 1
• 30 citations
  Phase 1 Expansion Cohort of Ramucirumab Plus Pembrolizumab in Advanced Treatment-Naive NSCLC.
  Roy S. Herbst, Hendrik Tobias Arkenau, Johanna C. Bendell, Edward Arrowsmith, Martin Wermke, Andres O. Soriano, Nicolas Penel, Rafael Santana-Davila, Helge Bischoff, I...> ;Journal of Thoracic Oncology. 2021 Feb 1
• 17 citations
  Ramucirumab in Combination with Pembrolizumab in Treatment-Naïve Advanced Gastric or GEJ Adenocarcinoma: Safety and Antitumor Activity from the Phase 1a/b JVDF Trial.
  Ian Chau, Nicolas Penel, Andres O. Soriano, Hendrik-Tobias Arkenau, Jennifer L. Cultrera, Rafael Santana-Davila, Emiliano Calvo, Christophe Le Tourneau, Lars Zender, J...> ;Cancers. 2020 Oct 15
• 13 citations
  A Pilot Study of Atezolizumab Plus Hypofractionated Image Guided Radiation Therapy for the Treatment of Advanced Non-Small Cell Lung Cancer.
  Angel Qin, Ramesh Rengan, Sylvia Lee, Rafael Santana-Davila, Bernardo H. L. Goulart, Renato G. Martins, Christina S. Baik, Gregory P. Kalemkerian, Khaled A. Hassan, Br...> ;International Journal of Radiation Oncology, Biology, Physics. 2020 Sep 1
• 2 citations
  Hyperprogressive Disease After Treatment With Checkpoint Inhibitors: Time for Prospective Studies.
  Rafael Santana-Davila> ;JAMA Oncology. 2020 Jul 1
• 8 citations
  Duration of Targeted Therapy in Patients With Advanced Non-small-cell Lung Cancer Identified by Circulating Tumor DNA Analysis.
  Karen L. Reckamp, Tejas Patil, Kedar Kirtane, Thereasa A. Rich, Carin R. Espenschied, Caroline M. Weipert, Victoria M. Raymond, Rafael Santana-Davila, Robert C. Doebel...> ;Clinical Lung Cancer. 2020 Jun 20
• 101 citations
  A Phase II Trial of Pembrolizumab and Vorinostat in Recurrent Metastatic Head and Neck Squamous Cell Carcinomas and Salivary Gland Cancer.
  Cristina P. Rodriguez, Qian Vicky Wu, Jenna M. Voutsinas, Jonathan R. Fromm, Xiuyun Jiang, Venu G. Pillarisetty, Sylvia Lee, Rafael Santana-Davila, Bernardo H. L. Goul...> ;Clinical Cancer Research. 2020 Feb 15
• 180 citations
  Efficacy and Safety of Rovalpituzumab Tesirine in Third-Line and Beyond Patients with DLL3-Expressing, Relapsed/Refractory Small-Cell Lung Cancer: Results From the Pha...
  Daniel Morgensztern, Benjamin Besse, Laurent Greillier, Rafael Santana-Davila, Neal Ready, Christine L. Hann, Bonnie S. Glisson, Anna F. Farago, Afshin Dowlati, Charle...> ;Clinical Cancer Research. 2019 Dec 1
• 1008 citations
  Non–Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment
  Narjust Duma, Rafael Santana-Davila, Julian R. Molina> ;Mayo Clinic Proceedings. 2019 Aug 1
• 168 citations
  Ramucirumab plus pembrolizumab in patients with previously treated advanced non-small-cell lung cancer, gastro-oesophageal cancer, or urothelial carcinomas (JVDF): a m...
  Roy S. Herbst, Hendrik-Tobias Arkenau, Rafael Santana-Davila, Emiliano Calvo, Luis Paz-Ares, Philippe A. Cassier, Johanna C. Bendell, Nicolas Penel, Matthew G Krebs, J...> ;The Lancet. Oncology. 2019 Aug 1
• 1 citations
  Head and Neck Cancer in Elderly Patients: What to Do When Data Are Limited?
  Rafael Santana-Davila> ;Journal of Oncology Practice. 2018 Sep 11
• 7 citations
  Racial disparity in oncologic and quality-of-life outcomes in patients with locally advanced head and neck squamous cell carcinomas enrolled in a randomized phase 2 tr...
  Margaret K. Guerriero, Mary W. Redman, Kelsey Baker, Renato G. Martins, Keith D. Eaton, Laura Qm Chow, Rafael Santana-Davila, Christina S. Baik, Bernardo H. L. Goulart...> ;Cancer. 2018 Jul 1
• 64 citations
  A Phase I Clinical Trial of AZD1775 in Combination with Neoadjuvant Weekly Docetaxel and Cisplatin before Definitive Therapy in Head and Neck Squamous Cell Carcinoma
  Eduardo Mendez, Cristina P. Rodriguez, Michael C. Kao, Sharat Raju, Ahmed Diab, R. Alex Harbison, Eric Q. Konnick, Ganesh Mugundu, Rafael Santana-Davila, Renato G. Mar...> ;Clinical Cancer Research. 2018 Jun 15
• 12 citations
  Harnessing the Immune System as a Therapeutic Tool in Virus-Associated Cancers.
  Rafael Santana-Davila, Shailender Bhatia, Laura Q.M. Chow> ;JAMA Oncology. 2017 Jan 1
• 13 citations
  Treatment of Stage IIIA Non–Small-Cell Lung Cancer: A Concise Review for the Practicing Oncologist
  Rafael Santana-Davila, Renato G. Martins> ;Journal of Oncology Practice. 2016 Sep 21
• 33 citations
  Cisplatin versus carboplatin based regimens for the treatment of patients with metastatic lung cancer. An analysis of Veterans Health Administration data
  Rafael Santana-Davila, Aniko Szabo, Carlos Arce-Lara, Christina D. Williams, Michael J. Kelley, Jeff Whittle> ;Journal of Thoracic Oncology. 2014 May 1
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Journal Articles

• Evaluation and management of elderly patients with lung cancer.  
  Gore E, Movsas B, Santana-Davila R, Langer C, Semin Radiat Oncol, 1/1/2012
• Treatment options for patients with triple-negative breast cancer.  
  Santana-Davila, R. & Perez, E.A., J Hematol Oncol, 1/1/2010
• Capecitabine and temozolomide: design, implementation, and preliminary outcomes from a pilot project to ensure safe prescribing of oral chemotherapy.  
  Jatoi, A., Smith EL, Gunderson, HD, Hartgers, ML, Looker SA, Santana-Davila R, McWilliams RR, J Oncol Pract, 1/1/2010
• Rearrangements and Amplification of IER3 2 (IEX-1) Represent A Novel And Recurrent Molecular Abnormality In Myelodysplastic Syndromes (MDS).  
  Steensma DP, Neiger JD, Porcher JC, Keats JJ, Bergsagel PF, Dennis TR, Knudson RA, Santana-Davila R, Kumar R, Ketterling RP, Cancer Res, 1/1/2009
• Dysgranulopoiesis is an independent adverse prognostic factor in chronic myeloid disorders with an isolated interstitial deletion of chromosome 5q.  
  Chen D, Hoyer JD, Ketterling RP, Tefferi A, Steensma DP, Holtan SG, Santana-Davila R, Porrata LF, Dewald GW and Hanson CA, Leukemia, 1/1/2009
• Genetic aberrations and survival in plasma cell leukemia.  
  Tiedemann RE, Gonzalez-Paz N, Kyle RA, Santana-Davila R, Price-Troska T, Van Wier SA, Chng WJ, Ketterling RP, Gertz MA, Henderson K, Greipp PR, Dispenzieri A, Lacy MQ,..., Leukemia, 1/1/2008
• Primary myelofibrosis is the most frequent myeloproliferative neoplasm associated with del(5q): Clinicopathologic comparison of del(5q)-positive and -negative cases.  
  Santana-Davila R, Tefferi A, Holtan SG, Ketterling RP, Dewald GW, Knudson RA, Steensma DP, Chen D, Hoyer JD, Hanson CA, Leuk Res, 1/1/2008
• Chromosome 5q deletion: specific diagnoses and cytogenetic details among 358 consecutive cases from a single institution.  
  Santana-Davila R, Holtan SG, Dewald GW, Ketterling RP, Knudson RA, Hanson CA, Steensma DP, Tefferi A, Leuk Res, 1/1/2008
• Myelodysplastic syndromes associated with interstitial deletion of chromosome 5q: Clinicopathologic correlations and new insights from the prelenalidomide era.  
  Holtan SG, Santana-Davila R, Dewald GW, Khetterling RP, Knudson RA, Hoyer JD, Chen D, Hanson CA, Porrata L, Tefferi A, Steensma DP, Am J Hematol, 1/1/2008
• Ploidy status rarely changes in myeloma patients at disease progression.  
  Chng WJ, Winkler JM, Greipp PR, Jalal SM, Bergsagel PL, Chesi M, Trendle MC, Ahmann GJ, Henderson K, Blood E, Oken MM, Hulbert A, Van Wier SA, Santana-Davila R, Kyle R..., Leuk Res, 1/1/2006
• Prognostic factors for hyperdiploid-myelom: effects of chromosome 13 deletions and IgH translocations.  
  Chng WJ, Santana-Davila R, Van Wier SA, Ahmann GJ, Jalal SM, Bergsagel PL, Chesi M, Trendle MC, Jacobus S, Blood E, Oken MM, Henderson K, Kyle RA, Gertz MA, Lacy MQ, D..., Leukemia, 1/1/2006
• Clinical implication of centrosome amplification in plasma cell neoplasm.  
  Chng WJ, Ahmann GJ, Henderson K, Santana-Davila R, Greipp PR, Gertz MA, Lacy MQ, Dispenzieri A, Kumar S, Rajkumar SV, Lust JA, Kyle RA, Zeldenrust SR, Hayman SR, Fonse..., Blood, 1/1/2006
• FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS.  
  Chng WJ, Van Wier SA, Ahmann GJ, Winkler JM, Jalal SM, Bergsagel PL, Chesi M, Trendle MC, Oken MM, Blood E, Henderson K, Santana-Davila R, Kyle RA, Gertz MA, Lacy MQ, ..., Blood, 1/1/2005
• Quality of medical education in Mexico.  
  Santana-Davila R, Martinez C, Lancet, 1/1/2004
• The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma.  
  Fonseca R, Debes-Marun CS, Picken EB, Dewald GW, Bryant SC, Winkler JM, Blood E, Oken MM, Santana-Davila R, Gonzalez-Paz N, Kyle RA, Gertz MA, Dispenzieri A, Lacy MQ, ..., Blood, 1/1/2003
• Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma.  
  Debes-Marun CS, Dewald GW, Bryant S, Picken E, Santana-Davila R, Gonzalez-Paz N, Winkler JM, Kyle RA, Gertz MA, Witzig TE, Dispenzieri A, Lacy MQ, Rajkumar SV, Lust JA..., Leukemia, 1/1/2003
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Lectures

• Clinicopathological characteristics of subsequent breast cancers in patients with benign breast disease. 
  45th Annual Meeting of the American Society of Clinical Oncology, Orlando, FL - 1/1/2009
• Deletion 5q in Acute Myeloid Leukemia (AML): a Clinicopathological Description of 79 Cases From a Single Institution. 
  50th Annual Meeting of the American Society of Hematology, San Francisco, CA - 1/1/2008
• Deletion 5q in WHO- Defined Myeloproliferative Neoplasms: A Clinicopathological Description 
  49th Annual Meeting of the American Society of Hematology, Atlanta, GA - 1/1/2007
• Trisomy 13 in Hematological Malignancies" 
  43rd Annual Meeting of the American Society of Clinical Oncology, Chicago, IL - 1/1/2007
• "Polymorphisms Associated with Clinical Outcome in the Intergroup Trial S9321, Comparing High Dose Therapy with Standard Dose Therapy for Myeloma on, on Behalf of ECOG... 
  46th Annual Meeting of the American Society of Hematology, San Diego, CA - 1/1/2004
• "Hamartoma of the pulmonic valve, a rare type of primary cardiac tumour" 
  American College of Physicians, Minnesota Chapter, Brooklyn Park, MN - 1/1/2003
• "High Incidence of p53 Deletion in Plasma Cell Leukemia (PCL), and Multiple Myeloma (MM) with Leukemic Transformation (MMLT)" 
  45th Annual Meeting of the American Society of Hematology, San Diego CA - 1/1/2003
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