RafazHoqueMD

PubMed

• 29 citations
  Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct-Ligated Mouse.
  Shi-Ying Cai, Maoxu Ge, Albert Mennone, Rafaz Hoque, Xinshou Ouyang, James L. Boyer> ;Cellular and Molecular Gastroenterology and Hepatology. 2020 Jan 1
• 10 citations
  Ammonia-induced brain edema requires macrophage and T cell expression of Toll-like receptor 9
  G.M. Vijay, Changyun Hu, Jian Peng, Irma Garcia-Martinez, Rafaz Hoque, Rejina Verghis, Yun Ma, Wajahat Z. Mehal, Debbie L. Shawcross, Li Wen> ;Cellular and Molecular Gastroenterology and Hepatology. 2019 Jan 1
• 10 citations
  Erratum: Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis (Cell Metabolism (2018) 27(2) (339–350.e3)(S1550413118300561)(10.1016...
  Xinshou Ouyang, Sheng Na Han, Ji Yuan Zhang, Evangelos Dioletis, Balázs Tamás Németh, Pal Pacher, Dechun Feng, Ramon Bataller, Joaquín Cabezas, Peter Stärkel, Joan Cab...> ;Cell Metabolism. 2018 May 1
• 43 citations
  β-Hydroxybutyrate protects from alcohol-induced liver injury via a Hcar2-cAMP dependent pathway.
  Yonglin Chen, Xinshou Ouyang, Rafaz Hoque, Irma Garcia-Martinez, Muhammad N. Yousaf, Sarah Tonack, Stefan Offermanns, Laurent Dubuquoy, Alexandre Louvet, Philippe Math...> ;Journal of Hepatology. 2018 Sep 1
• 25 citations
  Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis.
  Xinshou Ouyang, Sheng-Na Han, Ji-Yuan Zhang, Evangelos Dioletis, Balazs Tamas Nemeth, Pal Pacher, Dechun Feng, Ramon Bataller, Joaquin Cabezas, Peter Stärkel, Joan Cab...> ;Cell Metabolism. 2018 Feb 6
• 7 citations
  Update on innate immunity and perspectives on metabolite regulation in acute pancreatitis.
  Rafaz Hoque> ;Current Opinion in Gastroenterology. 2016 Nov 1
• 319 citations
  Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9.
  Irma Garcia-Martinez, Nicola Santoro, Yonglin Chen, Rafaz Hoque, Xinshou Ouyang, Sonia Caprio, Mark J. Shlomchik, Robert L. Coffman, Albert Candia, Wajahat Z. Mehal> ;The Journal of Clinical Investigation. 2016 Mar 1
• 41 citations
  Inflammasomes in pancreatic physiology and disease.
  Rafaz Hoque, Wajahat Z. Mehal> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2015 Apr 15
• 23 citations
  Activation of N-methyl-d-aspartate receptor downregulates inflammasome activity and liver inflammation via a β-arrestin-2 pathway
  Ahmad Farooq, Rafaz Hoque, Xinshou Ouyang, Ahsan Farooq, Ayaz Ghani, Kaimul Ahsan, Mateus T. Guerra, Wajahat Z. Mehal> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2014 Oct 1
• 307 citations
  Lactate reduces liver and pancreatic injury in Toll-like receptor- and inflammasome-mediated inflammation via GPR81-mediated suppression of innate immunity.
  Rafaz Hoque, Ahmad Farooq, Ayaz Ghani, Fred S. Gorelick, Wajahat Z. Mehal> ;Gastroenterology. 2014 Jun 1
• 29 citations
  Sterile inflammation in the liver and pancreas.
  Rafaz Hoque, Ahmad Farooq, Wajahat Z. Mehal> ;Journal of Gastroenterology and Hepatology. 2013 Aug 1
• 25 citations
  A Novel Small-Molecule Enantiomeric Analogue of Traditional (−)-Morphinans Has Specific TLR9 Antagonist Properties and Reduces Sterile Inflammation-Induced Organ Damage
  Rafaz Hoque, Ahmad Farooq, Ahsan F. Malik, Bobby N. Trawick, David W. Berberich, Joseph P. McClurg, Karen P. Galen, Wajahat Z. Mehal> ;Journal of Immunology. 2013 Apr 15
• 25 citations
  Therapeutic strategies in inflammasome mediated diseases of the liver
  Rafaz Hoque, Yoram Vodovotz, Wajahat Z. Mehal> ;Journal of Hepatology. 2013 May 1
• 109 citations
  P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice
  Rafaz Hoque, Muhammed Adnan Sohail, Steven D. Salhanick, Ahsan F. Malik, Ayaz Ghani, Simon C. Robson, Wajahat Z. Mehal> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2012 May 15
• 103 citations
  Sterile inflammatory response in acute pancreatitis.
  Rafaz Hoque, Ahsan F. Malik, Fred S. Gorelick, Wajahat Z. Mehal> ;Pancreas. 2012 Apr 1
• 72 citations
  Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response
  Ahsan F. Malik, Rafaz Hoque, Xinshou Ouyang, Ayaz Ghani, Enping Hong, Khadija Khan, Laura Beth Moore, Gilbert Ng, Fay Munro, Richard A. Flavell, Yan Shi, Themis R. Kyr...> ;Proceedings of the National Academy of Sciences of the United States of America. 2011 Dec 13
• 102 citations
  Loss of CFTR Affects Biliary Epithelium Innate Immunity and Causes TLR4–NF-κB—Mediated Inflammatory Response in Mice
  Romina Fiorotto, R. Scirpo, Michael Trauner, Luca Fabris, Rafaz Hoque, Carlo Spirli, Mario Strazzabosco> ;Gastroenterology. 2011 Oct 1
• 206 citations
  TLR9 and the NLRP3 Inflammasome Link Acinar Cell Death With Inflammation in Acute Pancreatitis
  Rafaz Hoque, Muhammad A. Sohail, Ahsan F. Malik, Sherhayar Sarwar, Yuhuan Luo, Ahsan U. Shah, Franck J. Barrat, Richard A. Flavell, Fred S. Gorelick, Sohail Z. Husain,...> ;Gastroenterology. 2011 Jul 1
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