RahulKakkarMD

PubMed

• Functional nitric oxide synthase mislocalization in cardiomyopathy.
  Heydemann A, Huber JM, Kakkar R, Wheeler MT, McNally EM> ;Journal of molecular and cellular cardiology.
• 358 citations
  The Dystrophin Glycoprotein Complex: Signaling Strength and Integrity for the Sarcolemma
  Rahul Kakkar, Elizabeth M. McNally> ;Circulation Research. 2004 Apr 30
• Ventricular assist device therapy normalizes inducible nitric oxide synthase expression and reduces cardiomyocyte apoptosis in the failing human heart.
  Patten RD, Denofrio D, El-Zaru M, Kakkar R, Saunders J, Celestin F, Warner K, Rastegar H, Khabbaz KR, Udelson JE, Konstam MA, Karas RH> ;Journal of the American College of Cardiology.
• Intramyocardial fibroblast myocyte communication.
  Kakkar R, Lee RT> ;Circulation research.
• Directions from Hecate: towards a multi-marker approach for heart failure assessment.
  Kakkar R, Lee RT> ;European journal of heart failure.
• 48 citations
  A dual apolipoprotein C-II mimetic-apolipoprotein C-III antagonist peptide lowers plasma triglycerides
  , , , , , , , , , , , , , , , , , , , > ;Science Translational Medicine. 2020 Jan 29
• Inflammation in Heart Failure: JACC State-of-the-Art Review.
  Murphy SP, Kakkar R, McCarthy CP, Januzzi JL> ;Journal of the American College of Cardiology.
• 2 citations
  Race, Interleukin-6,Genotype, and Cardiovascular Disease in Patients With Chronic Kidney Disease.
  Matt Devalaraja, Rahul Kakkar, Jing Chen, Jayanta Gupta, Sylvia E Rosas, Santosh Saraf, Jiang He, Alan Go, Dominic S Raj, Richard L Amdur, , Ian R Barrows> ;Journal of the American Heart Association. 2022 Sep 20
• 5 citations
  Left ventricular mass regression, all-cause and cardiovascular mortality in chronic kidney disease: a meta-analysis.
  Kevin C Maki, Meredith L Wilcox, Mary R Dicklin, Rahul Kakkar, Michael H Davidson> ;BMC Nephrology. 2022 Jan 16
• 1 citations
  A Phase 1 Randomized Dose-Escalation Study of a Human Monoclonal Antibody to IL-6 in CKD.
  Kristen L Nowak, Rahul Kakkar, Matt Devalaraja, Larry Lo, Wansu Park, Joga Gobburu, Douglas Kling, Michael Davidson, Michel Chonchol> ;Kidney360. 2021 Feb 25
• 34 citations
  Ziltivekimab for Treatment of Anemia of Inflammation in Patients on Hemodialysis: Results from a Phase 1/2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Tr...
  Pablo E. Pergola, Matt Devalaraja, Steven Fishbane, Michel Chonchol, Vandana Mathur, Mark T. Smith, Larry Lo, Rahul Kakkar, Michael H. Davidson, Kurt Herzog> ;Journal of the American Society of Nephrology. 2021 Jan 1
• Watching for Disease: the Changing Paradigm of Disease Screening in the Age of Consumer Health Devices.
  Varshney AS, Madias C, Kakkar R, Martin DT> ;Journal of general internal medicine. 2020-01-15
• 156 citations
  The clinical significance of interleukin-6 in heart failure: results from the BIOSTAT-CHF study.
  , , , , , , , , , , , , , , , , , , , > ;European Journal of Heart Failure. 2019 May 14
• 14 citations
  Serum Erythroferrone Levels Associate with Mortality and Cardiovascular Events in Hemodialysis and in CKD Patients: A Two Cohorts Study
  Rahul Kakkar, Larry Lo, Matt Devalaraja, Patrizia Pizzini, Claudia Torino, Daniela Leonardis, Sebastiano Cutrupi, Giovanni Tripepi, Francesca Mallamaci, Carmine Zoccali> ;Journal of Clinical Medicine. 2019 Apr 16
• 15 citations
  CXCR2 Inhibition – a novel approach to treating CoronAry heart DiseAse (CICADA): study protocol for a randomised controlled trial
  Jubin Joseph, Eliana Reyes, Josephine Guzman, Jim O'Doherty, Hannah McConkey, Rahul Kakkar, Nicholas Beckley, Abdel Douiri, Sally F. Barrington, Simon Redwood, Albert ...> ;Trials. 2017 Oct 11
• Inflammation and cardio-renal interactions in heart failure: a potential role for interleukin-6.
  Hanberg JS, Rao VS, Ahmad T, Chunara Z, Mahoney D, Jackson K, Jacoby D, Chen M, Wilson FP, Tang WHW, Kakkar R, Testani JM> ;European journal of heart failure. 2017-10-11
• 117 citations
  Myocardial pressure overload induces systemic inflammation through endothelial cell IL-33
  Wei-Yu Chen, Jaewoo Hong, Rahul Kakkar, Richard T. Lee> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Jun 9
• Interleukin 33 as a mechanically responsive cytokine secreted by living cells.
  Kakkar, R.,Hei, H.,Dobner, S.,Lee, R. T.> ;J. Biol. Chem.. 2012 Jan 05
• Role of ST2 in non-ST-elevation acute coronary syndrome in the MERLIN-TIMI 36 trial.
  Kohli P, Bonaca MP, Kakkar R, Kudinova AY, Scirica BM, Sabatine MS, Murphy SA, Braunwald E, Lee RT, Morrow DA> ;Clinical chemistry. 2011-11-17
• ST2 and adrenomedullin in heart failure.
  Kakkar, R.,Lee, R. T.> ;Heart Fail Clin. 2009 Jul 28
• The IL-33/ST2 pathway: therapeutic target and novel biomarker.
  Kakkar, R.,Lee, R. T.> ;Nat Rev Drug Discov. 2008 Oct 02
• Prevention of intravenous contrast-induced nephropathy in hospital inpatients.
  Kakkar, R.,Sobieszczyk, P.,Binkert, C. A.,Faxon, D. P.,Mortele, K. J.,Singh, A. K.> ;Crit Pathw Cardiol. 2008 May 07
• Mice lacking sulfonylurea receptor 2 (SUR2) ATP-sensitive potassium channels are resistant to acute cardiovascular stress.
  Stoller D, Kakkar R, Smelley M, Chalupsky K, Earley JU, Shi NQ, Makielski JC, McNally EM> ;Journal of molecular and cellular cardiology. 2007-08-01
• Spontaneous coronary vasospasm in KATP mutant mice arises from a smooth muscle-extrinsic process.
  Kakkar R, Ye B, Stoller DA, Smelley M, Shi NQ, Galles K, Hadhazy M, Makielski JC, McNally EM> ;Circulation research. 2006-02-02
• 30 citations
  Gender-specific patterns of left ventricular and myocyte remodeling following myocardial infarction in mice deficient in the angiotensin II type 1a receptor.
  Paul Bridgman, Rahul Kakkar, Michael I. Oliverio, Thomas M. Coffman, William M. Rand, Marvin A. Konstam, Michael E. Mendelsohn, Richard D. Patten> ;American Journal of Physiology. Heart and Circulatory Physiology. 2005 Mar 11
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