RajeshRamachandranMD

PubMed

• 3 citations
  Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1.
  Rochon, K., Bauer, B., Roethler, N., Buckley, Y., Su, C., Huang, W., Stoll, M., Yu, E., Taylor, D., Mears, J., Ramachandran, R.> ;Nature Communications. 2024 Feb 13
• 2 citations
  Clinical Utility of Cytokine Biomarker Analysis of Pancreatic Cyst Fluid Obtained by Endoscopic Ultrasound Fine Needle Aspiration: A Pilot Study.
  Larry Siu, Jenny Paredes, Vadim Kurbatov, Rajesh Ramachandran, Francesco M. Serafini, Evan Grossman, Frank G. Gress, Laura A. Martello> ;Pancreas. 2019 Sep 1
• 142 citations
  Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization
  Zhonghua Liu, Chuanping Wang, Jie Yang, Bowen Zhou, Rui Yang, Rajesh Ramachandran, Derek W. Abbott, Tsan Sam Xiao> ;Immunity. 2019 Jul 16
• 50 citations
  ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.
  Yuanyuan Zhao, Xiaoyan Sun, Di Hu, Domenick A. Prosdocimo, Charles L. Hoppel, Mukesh K. Jain, Rajesh Ramachandran, Xin Qi> ;Nature Communications. 2019 Mar 26
• 7 citations
  Geometric instability catalyzes mitochondrial fission.
  Ehsan Irajizad, Rajesh Ramachandran, Ashutosh Agrawal> ;Molecular Biology of the Cell. 2019 Jan 1
• 27 citations
  Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission
  Bin Lu, Bridget Kennedy, Ryan W. Clinton, Emily Jue Wang, Daniel R. McHugh, Natalia Stepanyants, Patrick J. Macdonald, Jason A. Mears, Xin Qi, Rajesh Ramachandran> ;Scientific Reports. 2018 Jul 18
• 115 citations
  Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission
  Natalia Stepanyants, Patrick J. Macdonald, Christopher A. Francy, Jason A. Mears, Xin Qi, Rajesh Ramachandran> ;Molecular Biology of the Cell. 2015 Sep 1
• 41 citations
  Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer
  Catherine Burkhart, Daria Fleyshman, Rachael Kohrn, Mairead Commane, Jennifer Garrigan, Vadim Kurbatov, Ilya Toshkov, Rajesh Ramachandran, Laura A. Martello, Katerina ...> ;Oncotarget. 2014 Nov 11
• 128 citations
  A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission.
  Patrick J. Macdonald, Natalia Stepanyants, Niharika Mehrotra, Jason A. Mears, Xin Qi, Hiromi Sesaki, Rajesh Ramachandran> ;Molecular Biology of the Cell. 2014 Jun 15
• 30 citations
  Alternate pleckstrin homology domain orientations regulate dynamin-catalyzed membrane fission.
  Niharika Mehrotra, Justin S. Nichols, Rajesh Ramachandran> ;Molecular Biology of the Cell. 2014 Mar 15
• 46 citations
  Vesicle scission: dynamin.
  Rajesh Ramachandran> ;Seminars in Cell & Developmental Biology. 2011 Feb 1
• 86 citations
  Membrane Insertion of the Pleckstrin Homology Domain Variable Loop 1 Is Critical for Dynamin-catalyzed Vesicle Scission
  Rajesh Ramachandran, Thomas J. Pucadyil, Ya-Wen Liu, Sharmistha Acharya, Marilyn Leonard, Vasyl Lukiyanchuk, Sandra L. Schmid> ;Molecular Biology of the Cell. 2009 Nov 15
• 87 citations
  Real-time detection reveals that effectors couple dynamin's GTP-dependent conformational changes to the membrane
  Rajesh Ramachandran, Sandra L. Schmid> ;The EMBO Journal. 2008 Jan 9
• 134 citations
  The dynamin middle domain is critical for tetramerization and higher-order self-assembly
  Rajesh Ramachandran, Mark C. Surka, Joshua S. Chappie, Douglas M. Fowler, Ted R. Foss, Byeong Doo Song, Sandra L. Schmid> ;The EMBO Journal. 2007 Jan 24
• 1 citations
  Guillain-Barre syndrome in children and adolescents--a retrospective analysis.
  Rajesh Ramachandran, Abraham Kuruvilla> ;Journal of the Indian Medical Association. 2004 Sep 1
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