Ralph J Deberardinis MD
Clinical Biochemical Genetics, Clinical Genetics, Ph.D. Medical Genetics, Pediatric Medical Genetics
Associate Professor, Chief of Pediatric Genetics and Metabolism, University of Texas Southwestern Medical Center, Southwestern Medical School
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5323 Harry Hines BlvdDallas, TX 75390
Phone+1 214-633-1803
Fax+1 214-648-5515
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Education & Training
Children's Hospital of PhiladelphiaResidency, Pediatrics/Medical Genetics and Genomics, 2000 - 2005
Perelman School of Medicine at the University of PennsylvaniaClass of 2000
Certifications & Licensure
TX State Medical License 2008 - 2025
PA State Medical License 2001 - 2008
American Board of Medical Genetics and Genomics Clinical Biochemical Genetics- American Board of Medical Genetics and Genomics Clinical Genetics and Genomics
Clinical Trials
- An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- Genetic and Metabolic Disease in Children Start of enrollment: 2015 Jun 01
Publications & Presentations
PubMed
- HighExpression Is Associated with Poor Prognosis,/Mutations, and Immunosuppressive Metabolism in Patient-Derived but Not Murine Lung Adenocarcinomas.Ling Cai, Thomas J Rogers, Reza Mousavi Jafarabad, Hieu Vu, Chendong Yang
Cancers. 2025-05-16 - The Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models.Ling Cai, Fangjiang Wu, Qinbo Zhou, Ying Gao, Bo Yao
Cancer Research. 2025-05-15 - CD44-mediated metabolic rewiring is a targetable dependency of IDH-mutant leukemia.Junhua Lyu, Yuxuan Liu, Ningning Liu, Hieu S Vu, Feng Cai
Blood. 2025-04-03
Journal Articles
- Gain‐of‐Function Variants in the ODC1 Gene Cause a Syndromic Neurodevelopmental Disorder Associated with Macrocephaly, Alopecia, Dysmorphic Features, and Neuroimaging ...Sanjeev V Kothare, Farrah Rajabi, Annapurna Poduri, Lance H Rodan, Ralph J DeBerardinis, American Journal of Medical Genetics Part A
- Genomic Regression Analysis of Coordinated ExpressionYang Xie, Ralph J DeBerardinis, Nature
Press Mentions
Children’s Research Institute Scientists Uncover Unique Pathway Tumors Use to Acquire Antioxidant LipidsJune 11th, 2025- HMN 2025: How FDA-Designated Orphan Drug May Improve Radiation Efficacy in Lung CancerMay 3rd, 2025
- FDA-Designated Orphan Drug Could Increase Radiation Efficacy in Lung CancerMay 1st, 2025
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Grant Support
- Human metabolic variation as a window into cancer initiation and progressionUT SOUTHWESTERN MEDICAL CENTER2017–2030
- Metabolic Regulators Of Tumor Cell GrowthNational Cancer Institute2011–2012
- Intermediary Metabolism In Tumor CellsNational Center For Research Resources2011
- Imaging Of Hyperpolarized Substrates In Animal Models Of CancerNational Center For Research Resources2010
- Metabolic Regulation In Growth Factor-Dependent CellsNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2010
- Metabolic Regulation In Growth Factor-Dependent CellsNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2007
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