RalphWeisslederMD

PubMed

• Magnetic Silica-Coated Fluorescent Microspheres (MagSiGlow) for Simultaneous Detection of Tumor-Associated Proteins.
  Elias A Halabi, Isabel Gessner, Katherine Yang, Jae-Jun Kim, Rupsa Jana, Hannah M Peterson, Joshua Spitzberg, Ralph Weissleder> ;Angewandte Chemie. 2024 Apr 5
• Sustained and Localized Drug Depot Release Using Radiation-Activated Scintillating Nanoparticles.
  Mikyung Kang, Jeremy Quintana, Huiyu Hu, Verônica C Teixeira, Sven Olberg, Leou Ismael Banla, Victoria Rodriguez, William L Hwang, Jan Schuemann, Sareh Parangi, Ralph ...> ;Advanced Materials. 2024 Feb 23
• Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype.
  Enbergs, N., Halabi, E., Goubet, A., Schleyer, K., Fredrich, I., Kohler, R., Garris, C., Pittet, M., Weissleder, R.> ;Advanced Science. 2024 Feb 11
• PARP trapping is governed by the PARP inhibitor dissociation rate constant.
  Gopal, A., Fernandez, B., Delano, J., Dubach, J., Weissleder, R.> ;Cell Chemical Biology. 2024 Jan 20
• Host-functionalization of macrin nanoparticles to enable drug loading and control tumor-associated macrophage phenotype.
  Biplab Sarkar, Sean P Arlauckas, Michael F Cuccarese, Christopher S Garris, Christopher B Rodell, Ralph Weissleder> ;Frontiers in Immunology. 2024 Jan 1
• Deep Learning Pipeline for Automated Cell Profiling from Cyclic Imaging.
  Landeros, C., Oh, J., Lee, H., Weissleder, R.> ;Research Square. 2023 Dec 18
• Perfusion Window Chambers Enable Interventional Analyses of Tumor Microenvironments.
  Anastasia Korolj, Rainer H Kohler, Ella Scott, Elias A Halabi, Kilean Lucas, Jonathan C T Carlson, Ralph Weissleder> ;Advanced Science. 2023 Dec 1
• 1 citations
  Highly Active Myeloid Therapy for Cancer.
  Ina R Fredrich, Elias A Halabi, Rainer H Kohler, Xinying Ge, Christopher S Garris, Ralph Weissleder> ;ACS Nano. 2023 Oct 24
• 1 citations
  Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery.
  Riddha Das, Elias A Halabi, Ina R Fredrich, Juhyun Oh, Hannah M Peterson, Xinying Ge, Ella Scott, Rainer H Kohler, Christopher S Garris, Ralph Weissleder> ;Advanced Science. 2023 Nov 1
• Longitudinal analysis of serum-derived extracellular vesicle RNA to monitor dacomitinib treatment response in EGFR-amplified recurrent glioblastoma patients.
  Anudeep Yekula, Tiffaney Hsia, Robert R Kitchen, Sudipto K Chakrabortty, Wei Yu, Syeda M Batool, Brian Lewis, Antoni J Szeglowski, Ralph Weissleder, Hakho Lee, Andrew ...> ;Neuro-Oncology Advances. 2023 Sep 4
• 28 citations
  macrophage polarity identifies a network of cellular programs that control human cancers.
  Ruben Bill, Pratyaksha Wirapati, Marius Messemaker, Whijae Roh, Beatrice Zitti, Florent Duval, Máté Kiss, Jong Chul Park, Talia M Saal, Jan Hoelzl, David Tarussio, Fab...> ;Science. 2023 Aug 4
• 13 citations
  Recruited macrophages elicit atrial fibrillation.
  Maarten Hulsmans, Maximilian J Schloss, I-Hsiu Lee, Aneesh Bapat, Yoshiko Iwamoto, Claudio Vinegoni, Alexandre Paccalet, Masahiro Yamazoe, Jana Grune, Steffen Pabel, N...> ;Science. 2023 Jul 14
• 1 citations
  Extracellular vesicle analysis of plasma allows differential diagnosis of atypical pancreatic serous cystadenoma.
  Katherine S Yang, Aileen O'Shea, Piotr Zelga, Andrew S Liss, Carlos Fernandez Del Castillo, Ralph Weissleder> ;Scientific Reports. 2023 Jul 6
• Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis.
  Carina Shiau, Jingyi Cao, Mark T Gregory, Dennis Gong, Xunqin Yin, Jae-Won Cho, Peter L Wang, Jennifer Su, Steven Wang, Jason W Reeves, Tae Kyung Kim, Youngmi Kim, Jim...> ;Biorxiv. 2023 Jun 29
• 2 citations
  Thyroid Cancers Exhibit Oncogene-Enhanced Macropinocytosis that Is Restrained by IGF1R and Promote Albumin-Drug Conjugate Response.
  Huiyu Hu, Thomas S C Ng, Mikyung Kang, Ella Scott, Ran Li, Jeremy M Quintana, Dylan Matvey, Venkata R Vantaku, Ralph Weissleder, Sareh Parangi, Miles A Miller> ;Clinical Cancer Research. 2023 Sep 1
• 4 citations
  Electrokinetically enhanced label-free plasmonic sensing for rapid detection of tumor-derived extracellular vesicles.
  Tae Joon Kwak, Taehwang Son, Jae-Sang Hong, Ursula Andrea Winter, Mi Ho Jeong, Charlotte McLean, Ralph Weissleder, Hakho Lee, Cesar M Castro, Hyungsoon Im> ;Biosensors & Bioelectronics. 2023 Oct 1
• 2 citations
  Light-Deactivated Fluorescent Probes (FLASH-Off) for Multiplexed Imaging.
  Elias A Halabi, Ralph Weissleder> ;Journal of the American Chemical Society. 2023 Apr 5
• 50 citations
  A neutrophil response linked to tumor control in immunotherapy.
  Jeremy Gungabeesoon, Nicolas A Gort-Freitas, Máté Kiss, Evangelia Bolli, Marius Messemaker, Marie Siwicki, Mehdi Hicham, Ruben Bill, Peter Koch, Chiara Cianciaruso, Fl...> ;Cell. 2023 Mar 30
• 14 citations
  Multiplexed analysis of EV reveals specific biomarker composition with diagnostic impact.
  Joshua D Spitzberg, Scott Ferguson, Katherine S Yang, Hannah M Peterson, Jonathan C T Carlson, Ralph Weissleder> ;Nature Communications. 2023 Mar 4
• 23 citations
  Monocytes re-enter the bone marrow during fasting and alter the host response to infection.
  Henrike Janssen, Florian Kahles, Dan Liu, Jeffrey Downey, Laura L Koekkoek, Vladimir Roudko, Darwin D'Souza, Cameron S McAlpine, Lennard Halle, Wolfram C Poller, Chris...> ;Immunity. 2023 Apr 11
• 10 citations
  T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles.
  Verena Turco, Kira Pfleiderer, Jessica Hunger, Natalie K Horvat, Kianush Karimian-Jazi, Katharina Schregel, Manuel Fischer, Gianluca Brugnara, Kristine Jähne, Volker S...> ;Nature Communications. 2023 Feb 11
• 9 citations
  Dual-Enhanced Plasmonic Biosensing for Point-of-Care Sepsis Detection.
  Lip Ket Chin, Jun-Yeong Yang, Benjamin Chousterman, Sunghoon Jung, Do-Geun Kim, Dong-Ho Kim, Seunghun Lee, Cesar M Castro, Ralph Weissleder, Sung-Gyu Park, Hyungsoon Im> ;ACS Nano. 2023 Feb 28
• 6 citations
  Plasmon-Enhanced Single Extracellular Vesicle Analysis for Cholangiocarcinoma Diagnosis.
  Mi Ho Jeong, Taehwang Son, Yoo Keung Tae, Chan Hee Park, Hee Seung Lee, Moon Jae Chung, Jeong Youp Park, Cesar M Castro, Ralph Weissleder, Jung Hyun Jo, Seungmin Bang,...> ;Advanced Science. 2023 Mar 1
• 9 citations
  Polymeric microneedles enable simultaneous delivery of cancer immunomodulatory drugs and detection of skin biomarkers.
  Pere Dosta, Núria Puigmal, Alexander M Cryer, Alma L Rodríguez, Ella Scott, Ralph Weissleder, Miles A Miller, Natalie Artzi> ;Theranostics. 2023 Jan 1
• 7 citations
  Dual Immunostimulatory Pathway Agonism through a Synthetic Nanocarrier Triggers Robust Anti-Tumor Immunity in Murine Glioblastoma.
  Sophie Lugani, Elias A Halabi, Juhyun Oh, Rainer H Kohler, Hannah M Peterson, Xandra O Breakefield, E Antonio A Chiocca, Miles A Miller, Christopher S Garris, Ralph We...> ;Advanced Materials. 2023 Feb 1
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Journal Articles

• Site Occupancy Calibration of Taxane Pharmacology in Live Cells and Tissues  
  Ralph Weissleder, MD, Proceedings of the National Academy of Sciences
• Direct Vascular Channels Connect Skull Bone Marrow and the Brain Surface Enabling Myeloid Cell Migration  
  Michael A Moskowitz, Ralph Weissleder, Nature