RamanSharmaMDFACC

PubMed

• Real-World Comparison of Clopidogrel With Ticagrelor and Prasugrel in Patients With Chronic Coronary Disease Who Underwent Atherectomy.
  Dhulipala, V. R., Mahin R Khan, Anoop N Koshy, Richard Tanner, Serdar Farhan, Manish Vinayak, Ali Farooq, Samantha Sartori, Yihan Feng, Alessandro Spirito, Ayush Arora...> ;The American Journal of Cardiology. 2024 Apr 15
• 1 citations
  Pharmacotherapy and revascularization strategies of peripheral artery disease.
  Syed, M., Prabhakaran, S., Song, D., Gandhi, K., Lavie, C., Alam, M., Sharma, R., Krittanawong, C., Khan, M., Moras, E.> ;Current Problems in Cardiology. 2024 Apr 1
• Single Center Outcomes of Percutaneous Deep Vein Arterialization in Patients with End-Stage Peripheral Artery Disease.
  Choinski, K., Rao, A., Krishnan, P., Tadros, R., Sharma, R., Faries, P.> ;Vascular and Endovascular Surgery. 2024 Jan 2
• 1 citations
  Lifestyle Approach and Medical Therapy of Lower Extremity Peripheral Artery Disease.
  Chayakrit Krittanawong, Johao Escobar, Hafeez Ul Hassan Virk, Mahboob Alam, Salim Virani, Carl J Lavie, K M Venkat Narayan, Raman Sharma, Ul Hassan, H.> ;The American Journal of Medicine. 2024 Mar 1
• Predictors of Suboptimal Lumen Expansion Following Intravascular Lithotripsy for Coronary In-Stent Restenosis.
  Keisuke Yasumura, Anoop N Koshy, Yuliya Vengrenyuk, Shingo Minatoguchi, Amit Hooda, Raman Sharma, Vishal Kapur, Joseph Sweeny, Samin K Sharma, Annapoorna S Kini> ;JACC. Cardiovascular Interventions. 2024 Jan 22
• 26 citations
  A Personalized Approach to Chronic Kidney Disease and Cardiovascular Disease: JACC Review Topic of the Week
  Ashton C. Lai, Solomon Bienstock, Raman Sharma, Karl Skorecki, Frans Beerkens, Rajeev Samtani, Andrew Coyle, Tonia Kim, Usman Baber, Anton Camaj, David A. Power, Valen...> ;Journal of the American College of Cardiology. 2021 Mar 23
• 22 citations
  Ebola virus antibody decay-stimulation in a high proportion of survivors
  Charlene Adaken, Janet T Scott, Raman Sharma, Robin Gopal, Steven Dicks, Saidia Niazi, Samreen Ijaz, Tansy Edwards, Catherine C. Smith, Christine P. Cole, Philip Kamar...> ;Nature. 2021 Jan 27
• 15 citations
  PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease.
  Ariamala Gopalsamy, Ann Aulabaugh, Amey Barakat, Kevin Beaumont, Shawn Cabral, Daniel P. Canterbury, Agustin Casimiro-Garcia, Jeanne S. Chang, Ming Z. Chen, Chulho Cho...> ;Journal of Medicinal Chemistry. 2021 Jan 14
• 6 citations
  Glasgow Early Treatment Arm Favirpiravir (GETAFIX) for adults with early stage COVID-19: A structured summary of a study protocol for a randomised controlled trial.
  Catherine Hanna, Kevin G. Blyth, Glenn A. Burley, Samantha Carmichael, Carol Evans, Samantha Hinsley, Ibrahim Khadra, Saye Khoo, Liz Anne Lewsley, Rob Jones, Raman Sha...> ;Trials. 2020 Nov 19
• 9 citations
  In Vitro Characterization of Ertugliflozin Metabolism by UDP-Glucuronosyltransferase and Cytochrome P450 Enzymes.
  Kimberly Lapham, Ernesto Callegari, Julie Cianfrogna, Jian Lin, Mark Niosi, Christine C. Orozco, Raman Sharma, Theunis C. Goosen> ;Drug Metabolism and Disposition. 2020 Oct 5
• 38 citations
  Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials.
  Edwin G Tse, Sevan D. Houston, Craig M. Williams, G. Paul Savage, Louis M. Rendina, Irene Hallyburton, Mark G. Anderson, Raman Sharma, Gregory S. Walker, R. Scott Obac...> ;Journal of Medicinal Chemistry. 2020 Oct 22
• 38 citations
  Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune Diseases
  Brian S. Gerstenberger, Catherine M. Ambler, Eric P. Arnold, Mary-Ellen Banker, Matthew Frank Brown, James D. Clark, Alpay Dermenci, Martin E. Dowty, Andrew Fensome, S...> ;Journal of Medicinal Chemistry. 2020 Aug 25
• 4 citations
  Incorporating genetic selection into individual‐based models of malaria and other infectious diseases
  Ian M. Hastings, Diggory Hardy, Katherine Kay, Raman Sharma> ;Evolutionary Applications. 2020 Aug 11
• 7 citations
  Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1
  Andrew Fensome, Catherine M. Ambler, Eric P. Arnold, Mary Ellen Banker, James D. Clark, Martin E. Dowty, Ivan Viktorovich Efremov, Andrew C. Flick, Brian S. Gerstenber...> ;Bioorganic & Medicinal Chemistry. 2020 May 15
• 14 citations
  Effective Application of Metabolite Profiling in Drug Design and Discovery
  Matthew A. Cerny, Amit S. Kalgutkar, R. Scott Obach, Raman Sharma, Douglas K. Spracklin, Gregory S. Walker> ;Journal of Medicinal Chemistry. 2020 Mar 6
• 5 citations
  Pharmacokinetics of TKM-130803 in Sierra Leonean patients with Ebola virus disease: plasma concentrations exceed target levels, with drug accumulation in the most seve...
  Janet T Scott, Raman Sharma, Luke W. Meredith, Jake Dunning, Catrin E. Moore, Foday Sahr, Steve A. Ward, Ian Goodfellow, Peter Horby> ;Ebiomedicine. 2020 Jan 14
• 11 citations
  The relative rate of kill of the MMV Malaria Box compounds provides links to the mode of antimalarial action and highlights scaffolds of medicinal chemistry interest
  Imran Ullah, Raman Sharma, Antonio Mete, Giancarlo A. Biagini, Dawn M. Wetzel, Paul Horrocks> ;The Journal of Antimicrobial Chemotherapy. 2020 Feb 1
• 6 citations
  Optimal treatments for severe malaria and the threat posed by artemisinin resistance
  Sam Jones, Eva Maria Hodel, Raman Sharma, Katherine Kay, Ian M. Hastings> ;The Journal of Infectious Diseases. 2019 Apr 8
• 1 citations
  Metabolism and excretion of (S)-6-(3-cyclopentyl-2-(4-trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid (PF-04991532), a hepatoselective glucokinase activat...
  Raman Sharma, Arthur Bergman, John Litchfield, Karen Atkinson, David J. Kazierad, Amit S. Kalgutkar> ;Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 2019 Mar 7
• 60 citations
  Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides
  Rachel H. Clare, Catherine Bardelle, Paul Harper, W. David Hong, Ulf Börjesson, Kelly L. Johnston, Matthew Collier, Laura Myhill, Andrew Cassidy, Darren Plant, Helen P...> ;Nature Communications. 2019 Jan 2
• 2 citations
  Coronary vasospastic angina: a rare case of ergonovine positivity and curative bilateral cardiac sympathectomy.
  Raman Sharma, Samin K. Sharma, Valentin Fuster> ;Eurointervention. 2018 Dec 20
• 100 citations
  Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino...
  Andrew Fensome, Catherine M. Ambler, Eric P. Arnold, Mary Ellen Banker, Matthew Frank Brown, Jill Chrencik, James D. Clark, Martin E. Dowty, Ivan Viktorovich Efremov, ...> ;Journal of Medicinal Chemistry. 2018 Aug 16
• 9 citations
  Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria
  Paul O´Neill, Paul A. Stocks, Sunil Sabbani, Natalie L. Roberts, Richard Amewu, Emma R. Shore, Ghaith Aljayyoussi, Iñigo Angulo-Barturen, María Belén, Jiménez-Díaz, Sa...> ;Bioorganic & Medicinal Chemistry. 2018 Jul 15
• 6 citations
  Harnessing biosynthesis and quantitative NMR for late stage functionalization of lead molecules: Application to the M1 positive allosteric modulator (PAM) program.
  Michael Aaron Brodney, Raman Sharma, John T. Lazzaro, Gregory S. Walker, R. Scott Obach> ;Bioorganic & Medicinal Chemistry Letters. 2018 Jun 15
• 15 citations
  Lead Diversification at the Nanomole Scale Using Liver Microsomes and Quantitative Nuclear Magnetic Resonance Spectroscopy: Application to Phosphodiesterase 2 Inhibitors.
  R. Scott Obach, Gregory S. Walker, Raman Sharma, Stephen Jenkinson, Tuan P. Tran, Antonia F. Stepan> ;Journal of Medicinal Chemistry. 2018 Mar 30
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