RandalJMayMD

PubMed

• 50 citations
  Alternative splice variants of DCLK1 mark cancer stem cells, promote self‐renewal and drug‐resistance, and can be targeted to inhibit tumorigenesis in kidney cancer
  Yang Ge, Nathaniel Weygant, Dongfeng Qu, Randal May, William L. Berry, Jiannan Yao, Parthasarathy Chandrakesan, Wei Zheng, Lichao Zhao, Karena L. Zhao, Michael Drake, ...> ;International Journal of Cancer. 2018 Sep 1
• 35 citations
  Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury
  Parthasarathy Chandrakesan, Randal May, Nathaniel Weygant, Dongfeng Qu, William L. Berry, Sripathi M. Sureban, Naushad Ali, Chinthalapally V. Rao, Mark M. Huycke, Mich...> ;Scientific Reports. 2016 Nov 23
• 23 citations
  (Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell Cycle Progression
  Charles B. Nguyen, Hari Kotturi, Gulam Waris, Altaf Mohammed, Parthasarathy Chandrakesan, Randal May, Sripathi M. Sureban, Nathaniel Weygant, Dongfeng Qu, Chinthalapal...> ;Cancer Research. 2016 Aug 15
• 27 citations
  Survival of patients with gastrointestinal cancers can be predicted by a surrogate microRNA signature for cancer stem-like cells marked by DCLK1 kinase
  Nathaniel Weygant, Yang Ge, Dongfeng Qu, John S. Kaddis, William L. Berry, Randal May, Parthasarathy Chandrakesan, Edwin Bannerman-Menson, Kenneth J. Vega, James J. To...> ;Cancer Research. 2016 Jul 15
• 39 citations
  Regulatory Roles of Dclk1 in Epithelial Mesenchymal Transition and Cancer Stem Cells
  Parthasarathy Chandrakesan, Janani Panneerselvam, Dongfeng Qu, Nathaniel Weygant, Randal May, Michael S. Bronze, Courtney W. Houchen> ;Journal of Carcinogenesis & Mutagenesis. 2016 Mar 7
• 42 citations
  Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism
  Sripathi M. Sureban, Mohammad F. Madhoun, Randal May, Dongfeng Qu, Naushad Ali, Javid Fazili, Nathaniel Weygant, Parthasarathy Chandrakesan, Kai Ding, Stanley Lightfoo...> ;Oncotarget. 2015 Oct 15
• 36 citations
  Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal
  Parthasarathy Chandrakesan, Randal May, Dongfeng Qu, Nathaniel Weygant, Vivian E. Taylor, James D. Li, Naushad Ali, Sripathi M. Sureban, Michael Qante, Timothy C. Wang...> ;Oncotarget. 2015 Sep 3
• 48 citations
  Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis.
  Dongfeng Qu, Nathaniel Weygant, Randal May, Parthasarathy Chandrakesan, Mohammad F. Madhoun, Naushad Ali, Sripathi M. Sureban, Guangyu An, Michael J. Schlosser, Courtn...> ;Plos One. 2015 Aug 18
• 24 citations
  Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury
  Sripathi M. Sureban, Randal May, Dongfeng Qu, Parthasarathy Chandrakesan, Nathaniel Weygant, Naushad Ali, Stan Lightfoot, Kai Ding, Shahid Umar, Michael J. Schlosser, ...> ;Plos One. 2015 Aug 13
• 23 citations
  Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases
  Naushad Ali, Parthasarathy Chandrakesan, Charles B. Nguyen, Sanam Husain, Allison F. Gillaspy, Mark M. Huycke, William L. Berry, Randal May, Dongfeng Qu, Nathaniel Wey...> ;Oncotarget. 2015 Apr 30
• 35 citations
  Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression
  Altaf Mohammed, Naveena B. Janakiram, Venkateshwar Madka, Misty Brewer, Rebekah L. Ritchie, Stan Lightfoot, Gaurav Kumar, Michael Sadeghi, Jagan M.R. Patlolla, Hiroshi...> ;Oncotarget. 2015 Apr 1
• 41 citations
  Doublecortin-Like Kinase 1 Is Elevated Serologically in Pancreatic Ductal Adenocarcinoma and Widely Expressed on Circulating Tumor Cells
  Dongfeng Qu, Jeremy J. Johnson, Parthasarathy Chandrakesan, Nathaniel Weygant, Randal May, Nicole M. Aiello, Andrew D. Rhim, Lichao Zhao, Wei Zheng, Stanley Lightfoot,...> ;Plos One. 2015 Feb 27
• 28 citations
  DCLK1 is detectable in plasma of patients with Barrett's esophagus and esophageal adenocarcinoma.
  Joshua Whorton, Sripathi M. Sureban, Randal May, Dongfeng Qu, Stan Lightfoot, Mohammad F. Madhoun, Milton Johnson, William M. Tierney, John T. Maple, Kenneth J. Vega, ...> ;Digestive Diseases and Sciences. 2015 Feb 1
• 80 citations
  DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma
  Nathaniel Weygant, Dongfeng Qu, Randal May, Ryan M. Tierney, William L. Berry, Lichao Zhao, Shweta Agarwal, Parthasarathy Chandrakesan, Harisha R. Chinthalapally, Nich...> ;Oncotarget. 2015 Jan 10
• 66 citations
  DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition
  Parthasarathy Chandrakesan, Nathaniel Weygant, Randal May, Dongfeng Qu, Harisha R. Chinthalapally, Sripathi M. Sureban, Naushad Ali, Stan Lightfoot, Shahid Umar, Court...> ;Oncotarget. 2014 Sep 2
• 101 citations
  XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism
  Sripathi M. Sureban, Randal May, Nathaniel Weygant, Dongfeng Qu, Parthasarathy Chandrakesan, Eddie Bannerman-Menson, Naushad Ali, Panayotis Pantazis, Christoph B. West...> ;Cancer Letters. 2014 Aug 28
• 90 citations
  Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1
  Nathaniel Weygant, Dongfeng Qu, William L. Berry, Randal May, Parthasarathy Chandrakesan, Daniel Owen, Sripathi M. Sureban, Naushad Ali, Ralf Janknecht, Courtney W. Ho...> ;Molecular Cancer. 2014 May 6
• 31 citations
  Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury
  Dongfeng Qu, Randal May, Sripathi M. Sureban, Nathaniel Weygant, Parthasarathy Chandrakesan, Naushad Ali, Linheng Li, Terrence A. Barrett, Courtney W. Houchen> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2014 Mar 1
• 31 citations
  Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism
  Naushad Ali, Heba Allam, Ted Bader, Randal May, Kanthesh M. Basalingappa, William L. Berry, Parthasarathy Chandrakesan, Dongfeng Qu, Nathaniel Weygant, Michael S. Bron...> ;Plos One. 2013 Nov 19
• 28 citations
  A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells.
  Scott T. Magness, Brent J. Puthoff, Mary Ann S. Crissey, James C.Y. Dunn, Susan J. Henning, Courtney W. Houchen, John S. Kaddis, Calvin J. Kuo, Linheng Li, John P. Lyn...> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2013 Oct 15
• Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury.
  May, R.,Qu, D.,Weygant, N.,Chandrakesan, P.,Ali, N.,Lightfoot, S. A.,Li, L.,Sureban, S. M.,Houchen, C. W.> ;Stem Cells. 2013 Oct 15
• 118 citations
  DCLK1 Regulates Pluripotency and Angiogenic Factors via microRNA-Dependent Mechanisms in Pancreatic Cancer
  Sripathi M. Sureban, Randal May, Dongfeng Qu, Nathaniel Weygant, Parthasarathy Chandrakesan, Naushad Ali, Stan Lightfoot, Panayotis Pantazis, Chinthalapally V. Rao, Ru...> ;Plos One. 2013 Sep 9
• Identification of the putative intestinal stem cell marker doublecortin and CaM kinase-like-1 in Barrett's esophagus and esophageal adenocarcinoma.
  Vega KJ, May R, Sureban SM, Lightfoot SA, Qu D, Reed A, Weygant N, Ramanujam R, Souza R, Madhoun M, Whorton J, Anant S, Meltzer SJ, Houchen CW> ;J. Gastroenterol. Hepatol.. 2012-04-01
• 63 citations
  Hepatitis C Virus-Induced Cancer Stem Cell-Like Signatures in Cell Culture and Murine Tumor Xenografts
  Naushad Ali, Heba Allam, Randal May, Sripathi M. Sureban, Michael S. Bronze, Ted Bader, Shahid Umar, Srikant Anant, Courtney W. Houchen> ;Journal of Virology. 2011 Dec 1
• 117 citations
  Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism
  Sripathi M. Sureban, Randal May, Fadee G. Mondalek, Dongfeng Qu, Sivapriya Ponnurangam, Panayotis Pantazis, Shrikant Anant, Rama P. Ramanujam, Courtney W. Houchen> ;Journal of Nanobiotechnology. 2011 Sep 19
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