RaviRIyerMD

PubMed

• 32 citations
  DNA Mismatch Repair and its Role in Huntington's Disease.
  Ravi R. Iyer, Anna Pluciennik> ;Journal of Huntington's Disease. 2021 Jan 1
• 31 citations
  Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair
  Jochen Genschel, Lyudmila Y. Kadyrova, Ravi R. Iyer, Basanta K. Dahal, Farid A. Kadyrov, Paul Modrich> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 May 9
• 82 citations
  DNA triplet repeat expansion and mismatch repair
  Ravi R. Iyer, Anna Pluciennik, Marek Napierala, Robert D. Wells> ;Annual Review of Biochemistry. 2015 Jun 2
• 50 citations
  Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system.
  Laura A. Lindsey-Boltz, Michael G. Kemp, Joyce T. Reardon, Vanessa DeRocco, Ravi R. Iyer, Paul Modrich, Aziz Sancar> ;The Journal of Biological Chemistry. 2014 Feb 21
• 56 citations
  Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
  Anna Pluciennik, Vickers Burdett, Celia Baitinger, Ravi R. Iyer, Kevin Shi, Paul Modrich> ;Proceedings of the National Academy of Sciences of the United States of America. 2013 Jul 23
• 3 citations
  Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutSβ.
  Quincy Tseng, Jillian Orans, Michael A. Hast, Ravi R. Iyer, Anita Changela, Paul Modrich, Lorena S. Beese> ;Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 2011 Aug 1
• 122 citations
  Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
  Jillian Orans, Elizabeth McSweeney, Ravi R. Iyer, Michael A. Hast, Homme W. Hellinga, Paul Modrich, Lorena S. Beese> ;Cell. 2011 Apr 15
• 190 citations
  PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
  Anna Pluciennik, Leonid Dzantiev, Ravi R. Iyer, Nicoleta Constantin, Farid A. Kadyrov, Paul Modrich> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Sep 14
• 38 citations
  MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ
  Ravi R. Iyer, Anna Pluciennik, Jochen Genschel, Miaw-sheue Tsai, Lorena S. Beese, Paul Modrich> ;The Journal of Biological Chemistry. 2010 Apr 9
• 67 citations
  Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks.
  Junhua Zhao, Aklank Jain, Ravi R. Iyer, Paul Modrich, Karen M. Vasquez> ;Nucleic Acids Research. 2009 Jul 1
• 35 citations
  The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair * ♦
  Ravi R. Iyer, Timothy J. Pohlhaus, Sihong Chen, Gregory L. Hura, Leonid Dzantiev, Lorena S. Beese, Paul Modrich> ;The Journal of Biological Chemistry. 2008 May 9
• 250 citations
  Structure of the Human MutSalpha DNA Lesion Recognition Complex.
  J.J. Warren, Timothy J. Pohlhaus, Anita Changela, Ravi R. Iyer, Paul Modrich, Lorena S. Beese> ;Molecular Cell. 2007 May 25
• 641 citations
  DNA mismatch repair: functions and mechanisms.
  Ravi R. Iyer, Anna Pluciennik, Vickers Burdett, Paul Modrich> ;Chemical Reviews. 2006 Feb 1
• 189 citations
  A Defined Human System That Supports Bidirectional Mismatch-Provoked Excision
  Leonid Dzantiev, Nicoleta Constantin, Jochen Genschel, Ravi R. Iyer, Peter M. J. Burgers, Paul Modrich> ;Molecular Cell. 2004 Jul 2
• 35 citations
  Long CTG Tracts from the Myotonic Dystrophy Gene Induce Deletions and Rearrangements during Recombination at the APRT Locus in CHO Cells
  James L. Meservy, R. Geoffrey Sargent, Ravi R. Iyer, Fung Chan, Gregory J. McKenzie, Robert D. Wells, John H. Wilson> ;Molecular and Cellular Biology. 2003 May 1
• 56 citations
  Sticky DNA, a Long GAA·GAA·TTC Triplex That Is Formed Intramolecularly, in the Sequence of Intron 1 of the Frataxin Gene
  Alexandre A. Vetcher, Marek Napierala, Ravi R. Iyer, Paul D. Chastain, Jack D. Griffith, Robert D. Wells> ;The Journal of Biological Chemistry. 2002 Oct 18
• 38 citations
  Long CTG·CAG Repeats from Myotonic Dystrophy Are Preferred Sites for Intermolecular Recombination
  Anna Pluciennik, Ravi R. Iyer, Marek Napierala, Jacquelynn E. Larson, Marcin Filutowicz, Robert D. Wells> ;The Journal of Biological Chemistry. 2002 Sep 13
• 62 citations
  GGA*TCC-interrupted triplets in long GAA*TTC repeats inhibit the formation of triplex and sticky DNA structures, alleviate transcription inhibition, and reduce genetic...
  Naoaki Sakamoto, Jacquelynn E. Larson, Ravi R. Iyer, Laura Montermini, Massimo Pandolfo, Robert D. Wells> ;The Journal of Biological Chemistry. 2001 Jul 20
• 22 citations
  Tandem duplication. A novel type of triplet repeat instability
  Anna Pluciennik, Ravi R. Iyer, Pawel Parniewski, Robert D. Wells> ;The Journal of Biological Chemistry. 2000 Sep 15
• 45 citations
  DNA polymerase III proofreading mutants enhance the expansion and deletion of triplet repeat sequences in Escherichia coli.
  Ravi R. Iyer, Anna Pluciennik, William A. Rosche, Richard R. Sinden, Robert D. Wells> ;The Journal of Biological Chemistry. 2000 Jan 21
• 50 citations
  Expansion and deletion of triplet repeat sequences in Escherichia coli occur on the leading strand of DNA replication.
  Ravi R. Iyer, Robert D. Wells> ;The Journal of Biological Chemistry. 1999 Feb 5
• Restriction of interferon gamma responsiveness and basal expression of the myeloid human Fc gamma R1b gene is mediated by a functional PU.1 site and a transcription in...
  Eichbaum QG, Iyer R, Raveh DP, Mathieu C, Ezekowitz RA> ;J. Exp. Med.. 1994-06-01
• 23 citations
  Structure of the murine Mac-2 gene. Splice variants encode proteins lacking functional signal peptides.
  Ian M. Rosenberg, Ravi R. Iyer, Bobby J. Cherayil, C Chiodino, Shiv Pillai> ;The Journal of Biological Chemistry. 1993 Jun 15
• 10 citations
  A matched set of cat vectors for rapid mutational analysis of eukaryotic promoters and enhancers.
  Ravi R. Iyer> ;Gene. 1991 Aug 30
• Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure.
  Benech, P. D., Sastry, K., Iyer, R. R., Eichbaum, Q. G., Raveh, D. P., Ezekowitz, R. A.> ;J Exp Med. 1992 Oct 1
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