ReganMichelleMemmottMD

PubMed

• CLO24-061: Overall Survival (OS) Impact for NSCLC Patients With irAE and Non-irAE Hospital Admissions During First-Line Pembrolizumab Treatment.
  Adam Khorasanchi, Songzhu Zhao, Lai Wei, Mingjia Li, Kevin Ho, Hamzah Abu-Sbeih, Evelyn Goodyear, Austin Secor, Peter Shields, Kai He, Jacob Kaufman, Regan Memmott, As...> ;Journal of the National Comprehensive Cancer Network. 2024 Apr 5
• Association Between Pretreatment Chest Imaging and Immune Checkpoint Inhibitor Pneumonitis Among Patients With Lung Cancer.
  Alexander Wong, Maria Riley, Songzhu Zhao, Jessica Zimmer, Matthew Viveiros, Jing Gennie Wang, Vincent Esguerra, Mingjia Li, Gabrielle Lopez, Kari Kendra, David P Carb...> ;Journal of the National Comprehensive Cancer Network. 2023 Nov 1
• 3 citations
  Mean platelet volume, thrombocytosis, and survival in non-small cell lung cancer patients treated with first-line pembrolizumab alone or with chemotherapy.
  Mingjia Li, Songzhu Zhao, Gabrielle Lopez, Austin Secor, Parthib Das, Nitya Surya, Madison Grogan, Sandip Patel, Karthik Chakravarthy, Abdul Miah, Daniel Spakowicz, Ga...> ;Cancer Immunology, Immunotherapy. 2023 Jul 1
• 38 citations
  Predictors of Response, Progression-Free Survival, and Overall Survival in Patients With Lung Cancer Treated With Immune Checkpoint Inhibitors.
  Regan M. Memmott, Adam R. Wolfe, David P. Carbone, Terence M. Williams> ;Journal of Thoracic Oncology. 2021 Jul 1
• 29 citations
  A Pilot Study of Sirolimus in Subjects with Cowden Syndrome or Other Syndromes Characterized by Germline Mutations in PTEN
  Takefumi Komiya, Gideon M. Blumenthal, Roopa DeChowdhury, Susan Fioravanti, Marc S. Ballas, John C. Morris, Thomas J. Hornyak, Stephen A. Wank, Stephen M. Hewitt, Bets...> ;The Oncologist. 2019 Dec 1
• 13 citations
  A phase I/II study of pemetrexed with sirolimus in advanced, previously treated non-small cell lung cancer.
  Takefumi Komiya, Regan M. Memmott, Gideon M. Blumenthal, Wendy B. Bernstein, Marc S. Ballas, Roopa De Chowdhury, Guinevere Chun, Cody J. Peer, William D. Figg, David J...> ;Translational Lung Cancer Research. 2019 May 13
• 25 citations
  Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer
  Shigeru Kawabata, Chun-Te Chiang, Junji Tsurutani, Hideaki Shiga, Matthew L. Arwood, Takefumi Komiya, Joell J. Gills, Regan M. Memmott, Phillip A. Dennis> ;Oncotarget. 2014 Feb 17
• 220 citations
  Repositioning metformin for cancer prevention and treatment.
  Brendan J. Quinn, Hiroshi Kitagawa, Regan M. Memmott, Joell J. Gills, Phillip A. Dennis> ;Trends in Endocrinology and Metabolism. 2013 Sep 1
• 60 citations
  Inhibition of lung tumorigenesis by metformin is associated with decreased plasma IGF-I and diminished receptor tyrosine kinase signaling.
  Brendan J. Quinn, Matthew Dallos, Hiroshi Kitagawa, Ajaikumar B. Kunnumakkara, Regan M. Memmott, M. Christine Hollander, Joell J. Gills, Phillip A. Dennis> ;Cancer Prevention Research. 2013 Aug 1
• 322 citations
  Metformin prevents tobacco carcinogen--induced lung tumorigenesis.
  Regan M. Memmott, Jose Mercado, Colleen R. Maier, Shigeru Kawabata, Stephen D. Fox, Phillip A. Dennis> ;Cancer Prevention Research. 2010 Sep 1
• 59 citations
  The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis
  Regan M. Memmott, Phillip A. Dennis> ;Clinical Cancer Research. 2010 Jan 1
• 35 citations
  LKB1 and mammalian target of rapamycin as predictive factors for the anticancer efficacy of metformin.
  Regan M. Memmott, Phillip A. Dennis> ;Journal of Clinical Oncology. 2009 Dec 1
• 289 citations
  Akt-dependent and -independent mechanisms of mTOR regulation in cancer.
  Regan M. Memmott, Phillip A. Dennis> ;Cellular Signalling. 2009 May 1
• 35 citations
  The chemopreventive agent myoinositol inhibits Akt and extracellular signal-regulated kinase in bronchial lesions from heavy smokers.
  Wei Han, Joell J. Gills, Regan M. Memmott, Stephen Lam, Phillip A. Dennis> ;Cancer Prevention Research. 2009 Apr 1
• 59 citations
  A Central Role for Foxp3+ Regulatory T Cells in K-Ras-Driven Lung Tumorigenesis
  Courtney A. Granville, Regan M. Memmott, Andria Balogh, Jacopo Mariotti, Shigeru Kawabata, Wei Han, Jaclyn LoPiccolo, Jason Foley, David J. Liewehr, Seth M. Steinberg,...> ;Plos One. 2009 Mar 30
• 148 citations
  A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity
  SunMi L. Palumbo, Regan M. Memmott, Diana J. Uribe, Yulia Krotova-Khan, Laurence H. Hurley, Scot W. Ebbinghaus> ;Nucleic Acids Research. 2008 Apr 1
• 40 citations
  Phosphatidylinositol Ether Lipid Analogues Induce AMP-Activated Protein Kinase–Dependent Death in LKB1-Mutant Non–Small Cell Lung Cancer Cells
  Regan M. Memmott, Joell J. Gills, Melinda G. Hollingshead, Margaret C. Powers, Zhi-Ping Chen, Bruce E. Kemp, Alan P. Kozikowski, Phillip A. Dennis> ;Cancer Research. 2008 Jan 15
• 45 citations
  Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38α, through MKK3/6-independent and -dependent mechanisms
  Joell J. Gills, S. Sianna Castillo, Chunyu Zhang, Pavel A. Petukhov, Regan M. Memmott, Melinda G. Hollingshead, Noel A. Warfel, Jiahuai Han, Alan P. Kozikowski, Philli...> ;The Journal of Biological Chemistry. 2007 Sep 14
• 147 citations
  Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway.
  Courtney A. Granville, Regan M. Memmott, Joell J. Gills, Phillip A. Dennis> ;Clinical Cancer Research. 2006 Feb 1
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