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Reisa Sperling, MD, Neurology, Boston, MA, Brigham and Women's Hospital

ReisaAnneSperlingMD

Neurology • Boston, MA

Director, Center for Alzheimer's Research and Treatment & Co-Director, Neuroimaging Core, Massachusetts Alzheimer's Disease Research Center & Professor of Neurology, Harvard Medical School

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Education & Training

  • Beth Israel Deaconess Medical Center/Harvard Medical School
    Beth Israel Deaconess Medical Center/Harvard Medical SchoolResidency, Neurology, 1992 - 1995
  • Brigham and Women's Hospital
    Brigham and Women's HospitalInternship, Internal Medicine, 1991 - 1992
  • Harvard Medical School
    Harvard Medical SchoolClass of 1991

Certifications & Licensure

  • MA State Medical License
    MA State Medical License 1995 - 2024

Awards, Honors, & Recognition

  • Super Doctor SuperDoctors.com

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease  
    Reisa Sperling, Michael S Rafii, Gary Romano, JAMA Neurology
  • Short-Term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment  
    Jeffrey M Burns, Keith A Johnson, Reisa A Sperling, Jason Karlawish, JAMA Neurology
  • Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease  
    Hyun-Sik Yang, Reisa Sperling, Matthew Schrag, Richard Mayeux, JAMA Neurology
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Authored Content

  • Short-Term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive ImpairmentAugust 2020
  • Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer DiseaseJune 2020
  • Association of Factors with Elevated Amyloid Burden in Clinically Normal Older IndividualsApril 2020
  • Sex, Amyloid, and APOE ε4 and Risk of Cognitive Decline in Preclinical Alzheimer's Disease: Findings from Three Well-Characterized CohortsMay 2018
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Press Mentions

  • Investigational Anti-Amyloid Therapy Started Before Alzheimer’s Symptoms No Longer Slows Memory Loss
    Investigational Anti-Amyloid Therapy Started Before Alzheimer’s Symptoms No Longer Slows Memory LossMarch 10th, 2023
  • Eli Lilly Alzheimer’s Treatment Solanezumab Failed to Slow Disease Progression
    Eli Lilly Alzheimer’s Treatment Solanezumab Failed to Slow Disease ProgressionMarch 8th, 2023
  • Alzheimer’s Study in Boston Looking at Possible Treatment to Prevent the Disease
    Alzheimer’s Study in Boston Looking at Possible Treatment to Prevent the DiseaseJanuary 26th, 2023
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Grant Support

  • Evolution Of Memory Related FMRI Activation Over The Course Of MCI And ADNational Institute On Aging2012
  • Implications Of Amyloid Deposition In Clinically Normal Older IndividualsNational Institute On Aging2009–2012
  • Mentoring Imaging Research In Early ADNational Institute On Aging2010–2011
  • Impact Of Amyloid On The Aging BrainNational Institute On Aging2010–2011
  • Evolution Of Memory-Related FMRI Activation Over The Course Of MCI And ADNational Institute On Aging2006–2010
  • Alzheimer'S Disease Neuroimaging Initiative (ADNI)National Center For Research Resources2007–2008
  • Trial Of Simvastatin To Slow The Progression Of Alzheimer'S DiseaseNational Center For Research Resources2005–2008
  • Trial Of Simvastation To Slow The Progression Of Alzheimer'S DiseaseNational Center For Research Resources2006
  • Reducing Homocysteine To Slow Cognitive Decline In Alzheimer'S DiseaseNational Center For Research Resources2006
  • Reducing Homocysteine To Slow Cognitive Decline In Alzheimer'SNational Center For Research Resources2005
  • Assessment Measures For Alzheimer'S Disease: Primary Prevention TrialsNational Center For Research Resources2005
  • Trial Of Simvastatin To Slow Progression Of Alzheimer'SNational Center For Research Resources2004
  • Efficacy And Safety Of Ly451395 In Probable Alzheimer'SNational Center For Research Resources2004
  • Face-Name Association: FMRI Studies In Aging &Mild ADNational Institute Of Neurological Disorders And Stroke2000–2004
  • Functional Magnetic Resonance Imaging (FMRI)National Institute On Aging2002

Hospital Affiliations

Dr. Reisa Sperling, Dr. Reisa Sperling, MD, Dr. R Sperling, Dr. Reisa Anne Sperling