ReneGonzalez-CotareloMDFACP

PubMed

• A phase 1 study of triple-targeted therapy with BRAF, MEK, and AKT inhibitors for patients with BRAF-mutated cancers.
  Alain P Algazi, James Moon, Christopher D Lao, Bartosz Chmielowski, Kari L Kendra, Karl D Lewis, Rene Gonzalez, Kevin Kim, John E Godwin, Brendan D Curti, Michaella La...> ;Cancer. 2024 May 15
• Introduction of a Polyethylene Glycol Linker Improves Uptake ofCu-NOTA-Conjugated Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptide in Melanoma.
  Zheng Qiao, Jingli Xu, Darrell R Fisher, Rene Gonzalez, Yubin Miao> ;Cancers. 2023 May 14
• Effects of Polyethylene Glycol and 8-Aminooctanoic Acid Linkers on Melanoma Uptake of [Tc]Tc-Tricarbonyl-NOTA-Conjugated Lactam-Cyclized α-MSH Peptides.
  Zheng Qiao, Jingli Xu, Rene Gonzalez, Yubin Miao> ;Bioconjugate Chemistry. 2023 May 17
• 12 citations
  Targeting MDSC Differentiation Using ATRA: A Phase I/II Clinical Trial Combining Pembrolizumab and All-Trans Retinoic Acid for Metastatic Melanoma.
  Richard P Tobin, Dasha T Cogswell, Victoria M Cates, Dana M Davis, Jessica S W Borgers, Robert J Van Gulick, Elizabeth Katsnelson, Kasey L Couts, Kimberly R Jordan, De...> ;Clinical Cancer Research. 2023 Apr 3
• 6 citations
  NovelCu-Labeled NOTA-Conjugated Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptides with Enhanced Tumor to Kidney Uptake Ratios.
  Zheng Qiao, Jingli Xu, Rene Gonzalez, Yubin Miao> ;Molecular Pharmaceutics. 2022 Jul 4
• 339 citations
  Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma
  , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Journal of Clinical Oncology. 2021 Nov 24
• 1 citations
  The Effect of Albumin-Binding Moiety on Tumor Targeting and Biodistribution Properties of 67Ga-Labeled Albumin Binder-Conjugated Alpha-Melanocyte-Stimulating Hormone P...
  Jingli Xu, Fabio Gallazzi, Darrell R. Fisher, Rene Gonzalez, Yubin Miao> ;Cancer Biotherapy & Radiopharmaceuticals. 2021 Nov 11
• 7 citations
  Adjuvant Therapy for Stage III Melanoma Without Immediate Completion Lymph Node Dissection
  Robert J. Torphy, Chloe Friedman, Felix Ho, Laura D. Leonard, Daniel Thieu, Karl D. Lewis, Theresa Medina, William A. Robinson, Rene Gonzalez, Camille L. Stewart, Nico...> ;Annals of Surgical Oncology. 2021 Sep 19
• 58 citations
  Overcoming PD-1 Blockade Resistance with CpG-A Toll-Like Receptor 9 Agonist Vidutolimod in Patients with Metastatic Melanoma.
  Antoni Ribas, Theresa Medina, John M. Kirkwood, Yousef Zakharia, Rene Gonzalez, Diwakar Davar, Bartosz Chmielowski, Katie M. Campbell, Riyue Bao, Heather Kelley, Aaron...> ;Cancer Discovery. 2021 Jul 29
• 4 citations
  Studying immunotherapy resistance in a melanoma autologous humanized mouse xenograft
  John Morton, Nathaniel Alzofon, Stephen B. Keysar, Tugs-Saikhan Chimed, Julie Reisinger, Loni Perrenoud, Phuong Le, Cera Nieto, Karina E. Gomez, Bettina Miller, Randi ...> ;Molecular Cancer Research. 2021 Feb 1
• 11 citations
  Safety and efficacy of combination nivolumab plus ipilimumab in patients with advanced melanoma: results from a North American expanded access program (CheckMate 218).
  F. Stephen Hodi, Paul B. Chapman, Mario Sznol, Christopher D. Lao, Rene Gonzalez, Michael Smylie, Gregory A. Daniels, John A. Thompson, Ragini R. Kudchadkar, William H...> ;Melanoma Research. 2021 Feb 1
• 1 citations
  Facile preparation of a novel Ga-67-labeled NODAGA-conjugated lactam-cyclized alpha-MSH peptide at room temperature for melanoma targeting.
  Jingli Xu, Zheng Qiao, Rene Gonzalez, Yubin Miao> ;Bioorganic & Medicinal Chemistry Letters. 2020 Oct 24
• 85 citations
  Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity.
  Felicity Newell, James S. Wilmott, Peter Johansson, Katia Nones, Venkateswar Addala, Pamela Mukhopadhyay, Natasa Broit, Carol M. Amato, Robert Van Gulick, Stephen H. K...> ;Nature Communications. 2020 Oct 16
• 17 citations
  Pre-Treatment Mutational and Transcriptomic Landscape of Responding Metastatic Melanoma Patients to Anti-PD1 Immunotherapy
  Carol M. Amato, Jennifer D. Hintzsche, Keith Wells, Allison Applegate, Nicholas T. Gorden, Victoria M. Vorwald, Richard P Tobin, Kelsey W. Nassar, Yiqun G. Shellman, J...> ;Cancers. 2020 Jul 17
• 30 citations
  Extended 5-Year Follow-up Results of a Phase Ib Study (BRIM7) of Vemurafenib and Cobimetinib in BRAF-Mutant Melanoma.
  Antoni Ribas, Adil Daud, Anna C. Pavlick, Rene Gonzalez, Karl D. Lewis, Omid Hamid, Thomas F. Gajewski, Igor Puzanov, Matthew Wongchenko, Isabelle Rooney, Jessie J. Hs...> ;Clinical Cancer Research. 2020 Jan 1
• 72 citations
  IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients.
  Richard P Tobin, Kimberly R. Jordan, Puja Kapoor, Eric Spongberg, Dana Davis, Victoria M. Vorwald, Kasey L. Couts, Dexiang Gao, Derek E. Smith, Jessica S W Borgers, St...> ;Frontiers in Oncology. 2019 Nov 8
• 11 citations
  Melanoma-Targeting Property of Y-90-Labeled Lactam-Cyclized α-Melanocyte-Stimulating Hormone Peptide
  Jingli Xu, Jianquan Yang, Rene Gonzalez, Darrell R. Fisher, Yubin Miao> ;Cancer Biotherapy & Radiopharmaceuticals. 2019 Nov 7
• 12 citations
  Inflammatory side effects of BRAF and MEK inhibitors.
  Anna G Mackin, Paula E. Pecen, Amanda L Dinsmore, Jennifer L. Patnaik, Rene Gonzalez, William A. Robinson, Alan G. Palestine> ;Melanoma Research. 2019 Oct 1
• 160 citations
  Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
  Ryan J. Sullivan, Omid Hamid, Rene Gonzalez, Jeffrey R. Infante, Manish R. Patel, F. Stephen Hodi, Karl D. Lewis, Hussein Abdul-Hassan Tawbi, Genevive Hernandez, Matth...> ;Nature Medicine. 2019 Jun 1
• 91 citations
  Therapy with high-dose Interleukin-2 (HD IL-2) in metastatic melanoma and renal cell carcinoma following PD1 or PDL1 inhibition
  Elizabeth I. Buchbinder, Janice P. Dutcher, Gregory A. Daniels, Brendan D. Curti, Sapna Pradyuman Patel, Shernan G. Holtan, Gerald P Miletello, Mayer Fishman, Rene Gon...> ;Journal for Immunotherapy of Cancer. 2019 Feb 18
• 26 citations
  68Ga-DOTA-GGNle-CycMSHhex targets the melanocortin-1 receptor for melanoma imaging
  Jianquan Yang, Jingli Xu, Rene Gonzalez, Thomas Lindner, Clemens Kratochwil, Yubin Miao> ;Science Translational Medicine. 2018 Nov 7
• 882 citations
  Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial.
  , , , , , , , , , , , , , , , , , > ;The Lancet. Oncology. 2018 Nov 1
• 125 citations
  Targeting myeloid-derived suppressor cells using all-trans retinoic acid in melanoma patients treated with Ipilimumab.
  Richard P Tobin, Kimberly R. Jordan, William A. Robinson, Dana Davis, Virginia F. Borges, Rene Gonzalez, Karl D. Lewis, Martin D. McCarter> ;International Immunopharmacology. 2018 Aug 16
• 19 citations
  Immune checkpoint inhibitors and radiosurgery for newly diagnosed melanoma brain metastases
  Tyler P. Robin, Robert E. Breeze, Derek E. Smith, Chad G. Rusthoven, Karl D. Lewis, Rene Gonzalez, Amanda Brill, Robin Saiki, Kelly Stuhr, Laurie E. Gaspar, Sana D. Ka...> ;Journal of Neuro-Oncology. 2018 Jun 16
• 92 citations
  Performance of a prognostic 31-gene expression profile in an independent cohort of 523 cutaneous melanoma patients
  Jonathan S. Zager, Brian R. Gastman, Sancy A. Leachman, Rene Gonzalez, Martin D. Fleming, Laura K. Ferris, Jonhan Ho, Alexander R. Miller, Robert W. Cook, Kyle R. Covi...> ;BMC Cancer. 2018 Feb 5
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