RichardLBowenMD

PubMed

• 8 citations
  Rationale, study design and implementation of the LUCINDA Trial: Leuprolide plus Cholinesterase Inhibition to reduce Neurologic Decline in Alzheimer's.
  Tracy Butler, Judith D. Goldberg, James E. Galvin, Thomas R. Maloney, Lisa D. Ravdin, Lidia Glodzik, Mony J. de Leon, Tsivia Hochman, Richard L. Bowen, Craig S. Atwood> ;Contemporary Clinical Trials. 2021 Jun 22
• 2 citations
  Septal hypertrophy and cell cycle re-entry in AD.
  Tracy Butler, Richard L. Bowen, Craig S. Atwood> ;Aging. 2019 Jan 22
• 4 citations
  Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data.
  Mark A. Smith, Richard L. Bowen, Richard Q. Nguyen, George Perry, Craig S. Atwood, Alfred A. Rimm> ;Journal of Alzheimer's Disease. 2018 Jan 1
• 6 citations
  Does the degree of endocrine dyscrasia post-reproduction dictate post-reproductive lifespan? Lessons from semelparous and iteroparous species
  Craig S. Atwood, Kentaro Hayashi, Sivan Vadakkadath Meethal, Tina K. Gonzales, Richard L. Bowen> ;Geroscience. 2017 Feb 1
• 5 citations
  Not All Androgen Deprivation Therapies Are Created Equal: Leuprolide and the Decreased Risk of Developing Alzheimer's Disease.
  Richard L. Bowen, Tracy Butler, Craig S. Atwood> ;Journal of Clinical Oncology. 2016 Jun 13
• 22 citations
  The endocrine dyscrasia that accompanies menopause and andropause induces aberrant cell cycle signaling that triggers re-entry of post-mitotic neurons into the cell cy...
  Craig S. Atwood, Richard L. Bowen> ;Hormones and Behavior. 2015 Nov 1
• 36 citations
  A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhi...
  Richard L. Bowen, George Perry, Chengjie Xiong, Mark A. Smith, Craig S. Atwood> ;Journal of Alzheimer's Disease. 2015 Jan 1
• 37 citations
  A Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease Pathogenesis
  Craig S. Atwood, Richard L. Bowen> ;Journal of Alzheimer's Disease. 2015 Jan 1
• 60 citations
  Tumor Necrosis Factor-Induced Cerebral Insulin Resistance in Alzheimer's Disease Links Numerous Treatment Rationales
  Ian A. Clark, Craig S. Atwood, Richard L. Bowen, Gilberto Paz-Filho, Bryce Vissel> ;Pharmacological Reviews. 2012 Oct 1
• 36 citations
  The reproductive-cell cycle theory of aging: An update
  Craig S. Atwood, Richard L. Bowen> ;Experimental Gerontology. 2011 Feb 1
• 28 citations
  The pregnancy hormones human chorionic gonadotropin and progesterone induce human embryonic stem cell proliferation and differentiation into neuroectodermal rosettes
  Miguel J. Gallego, Prashob Porayette, Maria M. Kaltcheva, Richard L. Bowen, Sivan Vadakkadath Meethal, Craig S. Atwood> ;Stem Cell Research & Therapy. 2010 Sep 13
• 53 citations
  Differential Processing of Amyloid-β Precursor Protein Directs Human Embryonic Stem Cell Proliferation and Differentiation into Neuronal Precursor Cells
  Prashob Porayette, Miguel J. Gallego, Maria M. Kaltcheva, Richard L. Bowen, Sivan Vadakkadath Meethal, Craig S. Atwood> ;The Journal of Biological Chemistry. 2009 Aug 28
• 27 citations
  Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-g...
  Sivan Vadakkadath Meethal, Tianbing Liu, Hsien W. Chan, Erika Ginsburg, Andrea C. Wilson, Danielle N. Gray, Richard L. Bowen, Barbara K. Vonderhaar, Craig S. Atwood> ;Journal of Neurochemistry. 2009 Aug 1
• 22 citations
  Activin receptor signaling regulates prostatic epithelial cell adhesion and viability.
  Derek P. Simon, Sivan Vadakkadath Meethal, Andrea C. Wilson, Miguel J. Gallego, Stephanie L. Weinecke, Erin Bruce, Patrick F. Lyons, Ryan J. Haasl, Richard L. Bowen, C...> ;Neoplasia. 2009 Apr 1
• 71 citations
  Reproductive hormones regulate the selective permeability of the blood-brain barrier ☆
  Andrea C. Wilson, Luca Clemente, Tianbing Liu, Richard L. Bowen, Sivan Vadakkadath Meethal, Craig S. Atwood> ;Biochimica Et Biophysica Acta. 2008 Jun 1
• 20 citations
  A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele
  Ryan J. Haasl, M Reza Ahmadi, Sivan Vadakkadath Meethal, Carey E. Gleason, Sterling C. Johnson, Sanjay Asthana, Richard L. Bowen, Craig S. Atwood> ;BMC Medical Genetics. 2008 Apr 25
• 11 citations
  A multi-hit endocrine model of intrinsic adult-onset asthma.
  Craig S. Atwood, Richard L. Bowen> ;Ageing Research Reviews. 2008 Apr 1
• 9 citations
  Menopause, estrogen, and gonadotropins in Alzheimer's disease.
  Gemma Casadesus, Raj K. Rolston, Kate M. Webber, Craig S. Atwood, Richard L. Bowen, George Perry, Mark A. Smith> ;Advances in Clinical Chemistry. 2008 Jan 1
• 19 citations
  Evidence for the Role of Luteinizing Hormone in Alzheimer Disease
  Kate M. Webber, Gemma Casadesus, Richard L. Bowen, George Perry, Mark A. Smith> ;Endocrine, Metabolic & Immune Disorders Drug Targets. 2007 Nov 30
• 108 citations
  Leuprolide acetate: a drug of diverse clinical applications.
  Andrea C. Wilson, Sivan Vadakkadath Meethal, Richard L. Bowen, Craig S. Atwood> ;Expert Opinion on Investigational Drugs. 2007 Oct 30
• 80 citations
  Increases in luteinizing hormone are associated with declines in cognitive performance.
  Gemma Casadesus, Erin L. Milliken, Kate M. Webber, Richard L. Bowen, Zhenmin Lei, Chinthalapally V. Rao, George Perry, Ruth A. Keri, Mark A. Smith> ;Molecular and Cellular Endocrinology. 2007 Apr 15
• 29 citations
  Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression.
  Tianbing Liu, Jay Wimalasena, Richard L. Bowen, Craig S. Atwood> ;Journal of Neurochemistry. 2007 Mar 1
• 13 citations
  Gonadotropins: a cohesive gender-based etiology of Alzheimer disease.
  Kate M. Webber, Gemma Casadesus, Craig S. Atwood, Richard L. Bowen, George Perry, Mark A. Smith> ;Molecular and Cellular Endocrinology. 2007 Jan 2
• 5 citations
  Metabolic clues regarding the enhanced performance of elite endurance athletes from orchiectomy-induced hormonal changes
  Craig S. Atwood, Richard L. Bowen> ;Medical Hypotheses. 2007 Jan 1
• 52 citations
  Human neurons express type I GnRH receptor and respond to GnRH I by increasing luteinizing hormone expression.
  Andrea C. Wilson, M. Shahriar Salamat, Ryan J. Haasl, Kelly M Roche, Anjali A. Karande, Sivan Vadakkadath Meethal, Ei Terasawa, Richard L. Bowen, Craig S. Atwood> ;The Journal of Endocrinology. 2006 Dec 1
• Join now to see all

Journal Articles

• Does the degree of endocrine dyscrasia post-reproduction dictate post-reproductive lifespan?  
  Atwood CS, Hayashi K, Meethal SV, Gonzales T, Bowen RL, Geroscience, 1/1/2017
• Not All Androgen Deprivation Therapies Are Created Equal: Leuprolide and the Decreased Risk of Developing Alzheimer's Disease  
  Bowen RL, Butler T, Atwood CS, J Clin Oncol, 1/10/2016
• A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhi...  
  Bowen RL, Perry G, Xiong C, Smith MA, Atwood CS, J Alzheimers Dis, 1/1/2015
• A Unified Hypothesis of Early-and Late-Onset Alzheimer's Disease Pathogenesis  
  Atwood CS, Bowen RL, J Alzheimers Dis, 1/1/2015
• Differential processing of amyloid-beta precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells  
  Porayette, P., Gallego, M.J., Kaltcheva, M.M., Bowen, R.L., Vadakkadath Meethal, S. and Atwood, C.S., Journal of Biological Chemistry, 1/1/2009
• Identification of a regulatory loop for the synthesis of neurosteroids: A StAR-dependent mechanism involving HPG axis receptors  
  Vadakkadath Meethal, S., Liu, T., Chan, H., Ginsburg, E., Wilson, A.C., Gray, D.N., Bowen, R.L., Vonderhaar, B.K. and Atwood, C.S., Journal of Neurochemistry, 1/1/2009
• Activin receptor signaling regulates prostatic Activin receptor signaling regulates prostatic  
  Simon, D., Vadakkadath Meethal, S., Wilson, A.C., Gallego, M.J., Weinecke, S.L., Bruce, E., Lyons, P., Haasl, R.J., Bowen, R.L. and Atwood, C.S., Neoplasia, 1/1/2009
• A multi-hit endocrine model of intrinsic adult-onset asthma  
  Atwood, C.S. and Bowen, R.L., Ageing Research Reviews, 1/1/2008
• Reproductive hormones regulate the selective permeability of the blood-brain barrier  
  Wilson, A.C., Clemente, L., Liu, T., Bowen, R.L., Vadakkadath Meethal, S. and Atwood, C.S., Biochemica Biophyica Acta-Molecular Basis of Disease, 1/1/2008
• A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E e4 Allele  
  Haasl, R.J., Reza Ahmadi, M., Vadakkadath Meethal, S., Gleason, C.E., Johnson, S.C., Asthana, S., Bowen, R.L. and Atwood, C.S., BMC Medical Genetics, 1/1/2008
• Increases in luteinizing hormone are associated with declines in cognitive performance  
  Casadesus, G., Milliken, E.L., Webber, K.M., Bowen, R.L., Lei, Z., Rao, C.V., Perry, G., Keri, R.A. and Smith, M.A., Mol. Cell. Endocrinol., 1/1/2007
• Luteinizing hormone receptor mediates neuronal pregnenolone production via upregulation of steroidogenic acute regulatory protein expression  
  Liu, T., Wimalasena, J., Bowen, R.L. and Atwood, C.S., Journal of Neurochemistry, 1/1/2007
• Gonadotropins: a cohesive gender-based etiology of Alzheimer disease  
  Webber, K.M., Casadesus, G., Atwood, C.S., Bowen, R.L., Perry, G. and Smith, M.A., Molecular and Cellular Endocrinology, 1/1/2007
• Evidence for the role of luteinizing hormone in Alzheimer disease  
  Webber, K.M., Casadesus, G., Bowen, R.L., Perry, G. and Smith, M.A., Endocr. Metab. Immune Disord. Drug Targets, 1/1/2007
• Luteinizing hormone modulates cognition and amyloid-Beta deposition in Alzheimer APP transgenic mice  
  Casadesus, G., Webber, K.M., Atwood, C.S., Pappolla, M.A., Perry, G., Bowen, R.L. and Smith, M.A., Biochim. Biophys. Acta, 1/1/2006
• Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease  
  Webber, K.M., Stocco, D.M., Casadesus, G., Bowen, R.L., Atwood, C.S., Previll, L.A., Harris, P.L.R., Zhu, X., Perry, G. and Smith, M.A., Mol. Neurodegener., 1/1/2006
• Metabolic clues regarding the enhanced performance of elite endurance athletes from orchiectomy-induced hormonal changes  
  Atwood, C.S. and Bowen, R.L., Medical Hypotheses, 1/1/2006
• Identification of a gonadotropin-releasing hormone receptor orthologue in Caenorhabditis elegans  
  Vadakkadath Meethal, S., Gallego, M., Haasl, R.J., Petras, S.J., Sgro, J.Y., Bowen, R.L. and Atwood, C.S., BMC Evolutionary Biology, 1/1/2006
• Steroidogenic acute regulatory protein (StAR): Evidence of gonadotropin-induced steroidogenesis in Alzheimer disease  
  Webber, K.M., Stocco, D.M., Casadesus, G., Bowen, R.L., Atwood, C.S., Previll, L.A., Harris, P.L., Zhu, X., Perry, G., Smith, M.A., Molecular Neurodegeneration, 1/1/2006
• Human extra-pituitary neurons possess GnRH I receptors that respond to GnRH by expressing luteinizing hormone  
  Wilson, A.C., Salamat, S., Haasl, R.J., Roche, K.M., Karande, A., Vadakkadath Meethal, S., Terasawa, E., Bowen, R.L. and Atwood, C.S., Journal of Endocrinology, 1/1/2006
• The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target  
  Webber, K.M., Casadesus, G., Zhu, X., Obrenovich, M.E., Atwood, C.S., Perry, G., Bowen, R.L. and Smith, M.A., Curr. Pharm. Design, 1/1/2006
• Antigonadotropins: a novel strategy to halt Alzheimer's disease neurodegeneration  
  Gregory, C.W., Atwood, C.S., Smith, M.A. and Bowen, R.L., Curr. Pharm. Design, 1/1/2006
• Evidence for the role of gonadotropin hormones in the development of Alzheimer disease  
  Casadesus, G., Atwood, C.S., Zhu, X., Hartzler, A.W., Webber, K.M., Perry, G., Bowen, R.L. and Smith, M.A., Cell. Mol. Life Sci., 1/1/2005
• Dysregulation of the hypothalamic-pituitary-gonadal axis with menopause and andropause promotes neurodegenerative senescence  
  Atwood, C.S., Meethal, S.V., Liu, T., Wilson, A.C., Gallego, M., Smith, M.A. and Bowen, R.L., J. Neuropathol. Exp. Neurol., 1/1/2005
• Feedback on a feedback loop: the hypothalamic-pituitary-gonadal axis  
  Atwood, C.S., Smith, M.A. and Bowen, R.L., J. Alzheimers Dis., 1/1/2005
• Join now to see all

Books/Book Chapters

• Advances in Clinical Chemistry 
  Chapter: Menopause, estrogen and gonadotropins in Alzheimer disease. 
  Page 139 - 153Casadesus, G., Rolston, R.K., Webber, K.M., Atwood, C.S., Bowen, R.L., Perry, G. and Smith, M.A.Editors: Makowski, G.S..Elsevier Inc., San Diego2008
• Alzheimer's Disease: New Advances 
  Chapter: Luteinizing hormone mediates Alzheimer-type changes in neurons. 
  Page 307 - 310Casadesus, G., Webber, K.M., Atwood, C.S., Bowen, R.L., Perry, G. and Smith, M.A.Editors: Iqbal, K., Winblad, B. and Avila, J..Medimond S.r.l., Bologna, Italy2006
• Alzheimer's Disease: New Advances 
  Chapter: Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease. 
  Page 581 - 584Webber, K.M., Stocco, D.M., Casadesus, G., Bowen, R.L., Atwood, C.S., Previll, L.A., Harris, P.L.R., Zhu, X., Perry, G. and Smith, M.A.Editors: Iqbal, K., Winblad, B. and Avila, J..Medimond S.r.l., Bologna, Italy2006
• Principles of Gender-Specific Medicine 
  Chapter: Mechanisms involved in gender differences in Alzheimer's disease: the role of leuteinizing and follicle stimulating hormones. 
  Page 1234 - 1237Bowen, R., Atwood, C.S., Perry, G. and Smith, M.A.Editors: Legato, M.L..Elsevier Academic Press, San Diego2004
• Join now to see all

Abstracts/Posters

• The pregnancy hormones human chorionic gonadotropin and progesterone induce human embryonic stem cell proliferation and differentiation into neuroectodermal rosettes.
  Gallego, M.J., Porayette, P., Kaltcheva, M.M., Bowen, R.L., Vadakkadath Meethal, S. and Atwood, C. S., Stem Cell Research & Therapy, 1/1/2010
• Trophoblastic hormones direct early human gastrulation and neurulation.
  Atwood, C.S., Porayette, P., Kaltcheva, M.M., Bowen, R.L., Vadakkadath Meethal, S., Gallego, M.J., Society for Neuroscience, 1/1/2009
• Identification of a cellular signaling pathway that regulates prostatic epithelial cell adhesion and viability.
  Vadakkadath Meethal, S., Simon, D.K., Wilson, A.C., Gallego, M.J., Weinecke, S.L., Bruce, E., Lyons, P., Haasl, R.J., Bowen, R.L. and Atwood, C.S., Departmentof Medicine Research Day, School of Medicine and Public Health, University of Wisconsin-Madison, 1/1/2009
• Gonadotropin-releasing hormone signaling in the aging brain: A recapitulation of its role in embryogenesis and its implications for Alzheimer's disease.
  Vadakkadath Meethal, S., Ockuly, J.C., Porayette, P., Gallego, M.J., Haworth, R.A., Bowen, R.L. and Atwood, C.S., Department of Medicine Research Day, School of Medicine and Public Health, University of Wisconsin-Madison, 1/1/2009
• A novel function for human chorionic gonadotropin in directing early human embryogenesis.
  Atwood, C.S., Gallego, M.J., Porayette, P., Kaltcheva, M.M., Bowen, R.L., Vadakkadath Meethal, S., Department of Medicine Research Day, School of Medicine and Public Health, University of Wisconsin-Madison, 1/1/2009
• Activin receptor signaling regulates prostatic epithelial cell adhesion and viability.
  Simon, D., Vadakkadath Meethal, S., Wilson, A.C., Gallego, M.J., Weinecke, S.L., Bruce, E., Lyons, P., Haasl, R.J., Bowen, R.L. and Atwood, C.S., Neoplasia, 1/1/2009
• Identification of a regulatory loop for the synthesis of neurosteroids: A StAR-dependent mechanism involving HPG axis receptors.
  Vadakkadath Meethal, S., Liu, T., Chan, H., Ginsburg, E., Wilson, A.C., Gray, D.N., Bowen, R.L., Vonderhaar, B.K. and Atwood, C.S., Journal of Neurochemistry, 1/1/2009
• Differential processing of amyloid-beta precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells.
  Porayette, P., Gallego, M.J., Kaltcheva, M.M., Bowen, R.L., Vadakkadath Meethal, S. and Atwood, C.S., Journal of Biological Chemistry, 1/1/2009
• Pleiotropic properties of luteinizing hormone in the brain.
  Atwood, C.S., Wilson, A.C., Porayette, P., Gallego, M.J., Bowen, R.L. and Vadakkadath Meethal, S., International Conference on Molecular and Clinical Aspects of Gonadal and Nongonadal Actions of Gonadotropins, 1/1/2008
• Identification of a negative feedback loop in the brain for the regulation of neurosteroid synthesis: Implications for Alzheimer's disease.
  Vadakkadath Meethal, S., Chan, H, Ginsburg, E., Wilson, A.C., Bowen, R.L., Vonderhaar, B.K. and Atwood, C.S., Alzheimer's and Dementia, 1/1/2008
• Gonadotropin-releasing hormone signaling in the aging brain: A recapitulation of its role in embryogenesis and its implications for Alzheimer's disease.
  Vadakkadath Meethal, S., Ockuly, J.C., Porayette, P., Gallego, M.J., Haworth, R.A., Bowen, R.L. and Atwood, C.S., Alzheimer's and Dementia, 1/1/2008
• Differential processing of amyloid-b precursor protein directs the proliferation and neuronal differentiation of human embryonic stem cells.
  Porayette, P., Gallego, M.J., Kaltcheva, M.M., Bowen, R.L., Vadakkadath Meethal, S. and Atwood, C.S., Alzheimer's and Dementia, 1/1/2008
• Alzheimer's disease pathology mediated by gonadotropins.
  Tarkowsky, S., Casadesus, G., Webber, K.M., Gregory, C.W., Bowen, R.L., Atwood, C.S., Perry, G. and Smith, M.A., 2007 Irwin H. Lepow Medical Student Research Day, 1/1/2007
• The potential role of a neuronal autocrine/paracrine mechanism in the regulation of neurosteroid production: Luteinzing hormone receptor mediates neurosteroid producti...
  Atwood, C.S., Wilson, A.C., Bowen, R.L., Vadakkadath Meethal, S. and Liu, T., Trabajos Del Instituto Cajal (4th International Meeting on Steroids and the Nervous System), Torino, Italy, 1/1/2007
• Extrapituitary expression of luteinizing hormone by human neurons possessing GnRH receptor 1.
  Wilson, A.C., Salamat, M.S., Meethal, S.V., Smith, M.A., Terasawa, E., Bowen, R.L. and Atwood, C.S., Front. Neuroendocrinol., 1/1/2006
• Identification of a gonadotropin-releasing hormone receptor homologue in Caenorhabditis elegans.
  Vadakkadath Meethal, S., Gallego, M.J., Haasl, R.J., Petras, S.J., Sgro, J.Y., Bowen, R.L. and Atwood, C.S., Frontiers in Neuroendocrinology, ICN 2006 Conference Abstracts (HPG Axis), 1/1/2006
• Evidence of gonadotropin-induced steroidogenesis in Alzheimer disease.
  Webber, K.M., Casadesus, G., Previll, L., Zhu, X., Bowen, R., Atwood, C., Perry, G., Stocco, D.M. and Smith, M.A., 29th Annual Biomedical Graduate Student Symposium, 1/1/2006
• Evidence of gonadotropin-induced steroidogenesis in Alzheimer's disease.
  Webber, K.M., Casadesus, G., Previll, L.A., Zhu, X., Gregory, C., Bowen, R., Atwood, C.S., Perry, G., Stocco, D.M. and Smith, M.A., Alzheimers Dementia, 1/1/2006
• Luteinizing hormone mediates Alzheimer-type changes in neurons.
  Casadesus, G., Webber, K.M., Atwood, C.S., Bowen, R.L., Perry, G. and Smith, M.A., Alzheimers Dementia, 1/1/2006
• Functional GnRH receptor signaling in neurons: implications for the treatment of Alzheimer's disease.
  Atwood, C.S., Salamat, M.S., Roche, K.M., Karande, A., Meethal, S.V., Smith, M.A., Terasawa, E., Bowen, R.L. and Wilson, A.C., Alzheimers Dementia, 1/1/2006
• Differentiation of human embryonic stem cells induces the processing of the amyloid-b precursor protein towards the amyloidogenic pathway.
  Porayette, P., Gallego, M.J., Vadakkadath Meethal, S., Bowen, R.L. and Atwood, C.S., Endocrinology and Reproductive Biology Annual Research Symposium, 1/1/2006
• Luteinizing hormone mediates Alzheimer-type changes in neurons.
  Casadesus, G., Webber, K.M., Atwood, C.S., Bowen, R.L., Perry, G., Smith, M.A., 10th International Conference on Alzheimer's Disease and Related Disorders, 1/1/2006
• Evidence of gonadotropin-induced steroidogenesis in Alzhiemer's disease.
  Webber, K.M., Casadesus, G., Previll, L.A., Zhu, X., Gregory, C., Bowen, R., Atwood, C.S., Perry, G., Stocco, D.M., Smith, M.A., 10th International Conference on Alzheimer's Disease and Related Disorders, 1/1/2006
• Functional GnRH receptor signaling in neurons: implications for the treatment of Alzheimer's disease.
  Atwood, C.S., Salamat, M.S., Roche, K.M., Karande, A., Vadakkadath Meethal, S., Smith, M.A., Terasawa, E., Bowen, R.L., Wilson, A.C., 10th International Conference on Alzheimer's Disease and Related Disorders, 1/1/2006
• Leuprolide acetate for the treatment Alzheimer's disease from bench to bedside: Background and interim data from a Phase II clinical trial.
  Bowen, R.L., Smith, M.A., Perry, G. and Atwood, C.S., 7th International Conference Alzheimer's and Parkinson's Diseases: Insights, Progress and Perspectives, 1/1/2005
• Join now to see all

Lectures

• "Neurodegeneration and the Forgotten Hormones of the HPG Axis" 
  Research Triangle Park, NC - 1/9/2005
• "What is Aging, What Is its Role in Alzheimer's Disease and What Can We Do About It?" 
  Philadelphia, PA - 1/1/2004
• "Alzheimer's Disease: From Molecular Mechanism to Drug Discovery" 
  Cancun, Mexico - 1/1/2004
• Insights to "Drug Discovery" 
  1/1/2004
• "Endocrine Changes Following Menopause/Andropause Drive Neurodegeneration During Senescence" 
  Baton Rouge, LA - 1/1/2003
• Alzheimer's Disease...Dying for Sex? 
  Montego Bay, Jamaica - 1/1/2002
• Gonadotropins Promote Biochemical Changes Associated with Alzheimer's Disease 
  Charleston, SC - 1/1/2002
• Join now to see all

Other

• "Villeda et al., The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature. 2011 Sep 1;477(7362):90-4." 
  Atwood, C.S. and Bowen, R.L., Commentary regarding "Do Blood-Borne factors Control Brain Aging?"
  http://www.alzforum.org/pap/annotation.asp?powID=121684#%7BF83760C6-8A6C-42B8-B3AB-5F7B0A8070E0%7D
  1/1/2012
• "Mosch B, Morawski M, Mittag A, Lenz D, Tarnok A, Arendt T. 2007, Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease. J Neurosci. 27, 685... 
  Atwood, C.S. and Bowen, R.L., Commentary entitled "Cycling to Nowhere" for the Alzheimer Research Forum
  http://www.alzforum.org/new/detail.asp?id=1620#{25127479-4EA9-4269-AEDF-7ED86053AE8E}
  1/1/2007
• The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease. 
  Casadesus, G., Garrett, M.R., Webber, K.M., Hartzler, A.W., Atwood, C.S., Perry, G., Bowen, R.L. and Smith, M.A., Drugs R D, 7, pp/ 187-193
  1/1/2006
• Forum Discussion: Caloric Restriction: Eat Less, Live Longer! 
  Bowen, R.L. and Atwood, C.S.
  http://www.alzforum.org/res/for/journal/mattson2/default.asp#bowen1
  1/1/2005
• SITE POLL: Does Abeta have a function? 
  Atwood C.S. and Bowen R.L.
  http://www.alzforum.org/com/pol/polldetail.asp?PollID=31#{2BDA27CA-B923-49E2-B37E-94B8C159D1DC}
  1/1/2004
• Comment: Sex, aging and Alzheimer's disease. 
  Atwood, C., Bowen, R., Casadesus, G., Perry, G., Smith, M.A. and Webber, K., Alzheimer Research Forum
  http://www.alzforum.org/com/pol/polldetail.asp?PollID=32
  1/1/2004
• Mitotic and gender parallels in Alzheimer disease: therapeutic opportunities. 
  Zhu, X., Webber, K.M., Casadesus, G., Raina, A.K., Lee, H.G., Marlatt, M., Hartzler, A., Atwood, C.S., Bowen, R., Perry, G. and Smith, M.A., Curr. Drug Targets
  1/1/2004
• Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease. 
  Casadesus, G., Zhu, X., Atwood, C.S., Webber, K.M., Perry, G., Bowen, R.L. and Smith, M.A., Curr. Drug Targets CNS Neurol. Disord.
  1/1/2004
• Alzheimer Genes in Cortical Development: How Do Their Prenatal Functions Relate to Dementia? 
  Bowen R.L., Live Discussion, Alzheimer Research Forum
  1/12/2002
• Alzheimer Immunotherapy Trial Grounded: Time to Reassess Safety and Vaccine Design. 
  Bowen R.L., Live Discussion, Alzheimer Research Forum
  1/5/2002
• Alzheimer's Disease Nomenclature. 
  Bowen R.L., Live Discussion, Alzheimer Research Forum
  1/14/2001
• Gonadal Hormone Withdrawal, Apoptosis, and Generation of Beta Amyloid Peptide: A Vicious Cycle of Amyloidogenesis and Neurotoxicity in Alzheimer's Disease. 
  Bowen R.L., Live Discussion, Alzheimer Research Forum
  1/5/2001
• Transcript of Live Discussion: Nomenclature Discussion. 
  Masters, C., Stanculescu, N., Bowen, R., Bishop, G., Morgan, J.P., Smith, M., Perry, G., Teplow, D., Kim, S.H., DeKosky, S., Chen, M., Atwood, C. and Kinoshita, J., Alzheimer Research Forum
  http://www.alzforum.org/res/for/journal/nomenclature/nom_transcript.asp
  1/1/2001
• "Pedersen WA, Wan R, Zhang P, Mattson MP. Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticot... 
  Bowen R.L., Commentary for Alzheimer Research Forum "Urocortin Is Potent Protector of Hippocampal Neurons"
• Join now to see all