RichardMJacksonMD

PubMed

• Correction to "A Machine Learning-Based Method To Improve Docking Scoring Functions and Its Application to Drug Repurposing"
  Kinnings, S.L., Liu, N., Tonge, P.J., Jackson, R.M., Xie, L., Bourne, P.E.> ;J Chem Inf Model. 2011 Apr 28
• ReverseScreen3D: a structure-based ligand matching method to identify protein targets.
  Kinnings, S.L., Jackson, R.M.> ;J Chem Inf Model. 2011 Mar 28
• A machine learning-based method to improve docking scoring functions and its application to drug repurposing.
  Kinnings, S.L., Liu, N., Tonge, P.J., Jackson, R.M., Xie, L., Bourne, P.E.> ;J Chem Inf Model. 2011 Feb 28
• Toward the discovery of functional transthyretin amyloid inhibitors: application of virtual screening methods.
  Simões, C. J., Mukherjee, T., Brito, R. M., Jackson, R. M.> ;J Chem Inf Model. 2010 Oct 25
• Hierarchical Bayesian Modeling of Pharmacophores in Bioinformatics.
  Mardia, K.V., Nyirongo, V.B., Fallaize, C.J., Barber, S., Jackson, R.M.> ;Biometrics. 2011 Jun
• The Mycobacterium tuberculosis drugome and its polypharmacological implications.
  Kinnings, S.L., Xie, L., Fung, K.H., Jackson, R.M., Xie, L., Bourne, P.E.> ;PLoS Comput Biol. 2010
• InCa-SiteFinder: a method for structure-based prediction of inositol and carbohydrate binding sites on proteins.
  Kulharia, M., Bridgett, S.J., Goody, R.S., Jackson, R.M.> ;J Mol Graph Model. 2009-10-01
• LigMatch: a multiple structure-based ligand matching method for 3D virtual screening.
  Kinnings, S.L., Jackson, R.M.> ;J Chem Inf Model. 2009-09-01
• Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response.
  Rice, G.I., Bond, J., Asipu, A., Brunette, R.L., Manfield, I.W., Carr, I.M., Fuller, J.C., Jackson, R.M., Lamb, T., Briggs, T.A., Ali, M., Gornall, H., Couthard, L.R.,...> ;Nat Genet. 2009-07-01
• Binding site similarity analysis for the functional classification of the protein kinase family.
  Kinnings, S.L., Jackson, R.M.> ;J Chem Inf Model. 2009-02-01
• Binding Site Similarity Analysis for the Functional Classification of the Protein Kinase Family.
  > ;J Chem Inf Model. 2009-01-13
• Information theory-based scoring function for the structure-based prediction of protein-ligand binding affinity.
  Kulharia, M., Goody, R.S., Jackson, R.M.> ;J Chem Inf Model. 2008 Oct
• Structure-based pharmacophore design and virtual screening for novel angiotensin converting enzyme 2 inhibitors.
  Rella, M., Rushworth, C.A., Guy, J.L., Turner, A.J., Langer, T., Jackson, R.M.> ;J Chem Inf Model. 2006-03-01
• A searchable database for comparing protein-ligand binding sites for the analysis of structure-function relationships.
  Gold, N.D., Jackson, R.M.> ;J Chem Inf Model. 2006-03-01
• Comparison of the ATP binding sites of protein kinases using conformationally diverse bisindolylmaleimides.
  Bartlett, S., Beddard, G.S., Jackson, R.M., Kayser, V., Kilner, C., Leach, A., Nelson, A., Oledzki, P.R., Parker, P., Reid, G.D., Warriner, S.L.> ;J Am Chem Soc. 2005 Aug 24
• Towards a structural classification of phosphate binding sites in protein-nucleotide complexes: an automated all-against-all structural comparison using geometric matc...
  Brakoulias, A., Jackson, R.M.> ;Proteins. 2004 Aug 1
• Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.
  Toomes, C., Bottomley, H.M., Jackson, R.M., Towns, K.V., Scott, S., Mackey, D.A., Craig, J.E., Jiang, L., Yang, Z., Trembath, R., Woodruff, G., Gregory-Evans, C.Y., Gr...> ;Am J Hum Genet. 2004 Apr
• Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence.
  Guy, J.L., Jackson, R.M., Acharya, K.R., Sturrock, E.D., Hooper, N.M., Turner, A.J.> ;Biochemistry. 2003 Nov 18
• Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modul...
  Macdonald, A., Mazaleyrat, S., McCormick, C., Street, A., Burgoyne, N. J., Jackson, R. M., Cazeaux, V., Shelton, H., Saksela, K., Harris, M.> ;J Gen Virol. 2005 Apr
• Delineation and modelling of a nucleolar retention signal in the coronavirus nucleocapsid protein.
  Reed, M. L., Dove, B. K., Jackson, R. M., Collins, R., Brooks, G., Hiscox, J. A.> ;Traffic. 2006 Jul
• Prediction of protein-protein interactions using distant conservation of sequence patterns and structure relationships.
  Espadaler, J., Romero-Isart, O., Jackson, R. M., Oliva, B.> ;Bioinformatics. 2005 Aug 15
• An evaluation of automated homology modelling methods at low target template sequence similarity.
  Dalton, J. A., Jackson, R. M.> ;Bioinformatics. 2007 Aug 1
• Q-fit: a probabilistic method for docking molecular fragments by sampling low energy conformational space.
  Jackson, R. M.> ;J Comput Aided Mol Des. 2002 Jan
• Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication.
  Johnson, R., Gamblin, R. J., Ooi, L., Bruce, A. W., Donaldson, I. J., Westhead, D. R., Wood, I. C., Jackson, R. M., Buckley, N. J.> ;Nucleic Acids Res. 2006
• Homology-modelling protein-ligand interactions: allowing for ligand-induced conformational change.
  Dalton, J. A., Jackson, R. M.> ;J Mol Biol. 2010 Jun 18
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