RichardLKleinMD

Urology • Sioux Falls, SD

Physician

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Office
1201 S Euclid Ave
Ste 301
Sioux Falls, SD 57105
Phone+1 605-328-8240

Fax+1 605-328-8241
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Summary

Dr. Richard Klein, MD is a board certified urologist in Sioux Falls, South Dakota. He is currently licensed to practice medicine in South Dakota and New Jersey.

Education & Training

Sovah Health-DanvilleResidency, Urology, 1973 - 1976
University of California (San Francisco)Residency, Surgery, 1971 - 1973
Saint Louis University School of MedicineClass of 1971

Certifications & Licensure

NJ State Medical License 1963 - 2017
SD State Medical License 1900 - 2014
American Board of Urology Urology

Awards, Honors, & Recognition

Fellow (FACS) American College of Surgeons

Publications & Presentations

PubMed

Glycosylated sphingolipids and progression to kidney dysfunction in type 1 diabetes.
Lopes-Virella, M. F.,Baker, N. L.,Hunt, K. J.,Hammad, S. M.,Arthur, J.,Virella, G.,Klein, R. L.> ;J Clin Lipidol. 2019 May 03
Association Between Inflammatory Markers and Progression to Kidney Dysfunction: Examining Different Assessment Windows in Patients With Type 1 Diabetes.
Baker, N. L.,Hunt, K. J.,Stevens, D. R.,Jarai, G.,Rosen, G. D.,Klein, R. L.,Virella, G.,Lopes-Virella, M. F.> ;Diabetes Care. 2017 Nov 10
Increased Plasma Levels of Select Deoxy-ceramide and Ceramide Species are Associated with Increased Odds of Diabetic Neuropathy in Type 1 Diabetes: A Pilot Study.
Hammad SM, Baker NL, El Abiad JM, Spassieva SD, Pierce JS, Rembiesa B, Bielawski J, Lopes-Virella MF, Klein RL> ;Neuromolecular Med.. 2016-07-07
Data on carotid intima-media thickness and lipoprotein subclasses in type 1 diabetes from the Diabetes Control and Complications Trial and the Epidemiology of Diabetes...
Basu, A.,Jenkins, A. J.,Zhang, Y.,Stoner, J. A.,Klein, R. L.,Lopes-Virella, M. F.,Timothy Garvey, W.,Lyons, T. J.> ;Data Brief. 2016 Jan 14
Plasma Prekallikrein Is Associated With Carotid Intima-Media Thickness in Type 1 Diabetes.
Jaffa, M. A.,Luttrell, D.,Schmaier, A. H.,Klein, R. L.,Lopes-Virella, M.,Luttrell, L. M.,Jaffa, A. A.> ;Diabetes. 2015 Nov 26
Associations between intensive diabetes therapy and NMR-determined lipoprotein subclass profiles in type 1 diabetes.
Zhang, Y.,Jenkins, A. J.,Basu, A.,Stoner, J. A.,Lopes-Virella, M. F.,Klein, R. L.,Lyons, T. J.> ;J. Lipid Res.. 2015 Dec 15
Nuclear magnetic resonance-determined lipoprotein subclasses and carotid intima-media thickness in type 1 diabetes.
Basu, A.,Jenkins, A. J.,Zhang, Y.,Stoner, J. A.,Klein, R. L.,Lopes-Virella, M. F.,Garvey, W. T.,Lyons, T. J.> ;Atherosclerosis. 2015 Nov 26
Microsomal Triglyceride Transfer Protein Transfers and Determines Plasma Concentrations of Ceramide and Sphingomyelin but Not Glycosylceramide.
Iqbal, J.,Walsh, M. T.,Hammad, S. M.,Cuchel, M.,Tarugi, P.,Hegele, R. A.,Davidson, N. O.,Rader, D. J.,Klein, R. L.,Hussain, M. M.> ;J. Biol. Chem.. 2015 Sep 10
50 citations
Decreased plasma levels of select very long chain ceramide species Are associated with the development of nephropathy in type 1 diabetes
Richard L. Klein, Samar M. Hammad, Nathaniel L. Baker, Kelly J. Hunt, Mohammed M. Al Gadban, Patricia A. Cleary, Gabriel Virella, Maria F. Lopes-Virella> ;Metabolism. 2014 Oct 1
Plasma total homocysteine and carotid intima-media thickness in type 1 diabetes: A prospective study.
Basu, A.,Jenkins, A. J.,Stoner, J. A.,Thorpe, S. R.,Klein, R. L.,Lopes-Virella, M. F.,Garvey, W. T.,Lyons, T. J.> ;Atherosclerosis. 2014 Jul 27
The predictive role of markers of Inflammation and endothelial dysfunction on the course of diabetic retinopathy in type 1 diabetes.
Rajab, H. A.,Baker, N. L.,Hunt, K. J.,Klein, R.,Cleary, P. A.,Lachin, J.,Virella, G.,Lopes-Virella, M. F.> ;J. Diabetes Complicat.. 2014 Dec 03
Skewing of immune cell cytokine production by mediators from adipocytes and endothelial cells.
Vielma, S. A.,Klein, R. L.,Levingston, C. A.,Young, M. R.> ;Adipocyte. 2014 Apr 11
Reply to comment on: Lopes-Virella MF, et al. Baseline Markers of Inflammation Are Associated With Progression to Macroalbuminuria in Type 1 Diabetic Subjects: Diabete...
Lopes-Virella, M. F.,Baker, N. L.,Hunt, K. J.,Cleary, P. A.,Klein, R.,Virella, G.> ;Diabetes Care. 2014 Feb 06
Clinical correlates of serum pigment epithelium-derived factor in type 2 diabetes patients.
Jenkins, A. J.,Fu, D.,Azar, M.,Stoner, J. A.,Kaufman, D. G.,Zhang, S.,Klein, R. L.,Lopes-Virella, M. F.,Ma, J. X.,Lyons, T. J.> ;J. Diabetes Complicat.. 2014 Feb 25
Apolipoprotein-defined and NMR lipoprotein subclasses in the veterans affairs diabetes trial.
Azar, M.,Lyons, T. J.,Alaupovic, P.,Stoner, J. A.,Quiroga, C.,Kaufman, D. G.,Lopes-Virella, M.,Klein, R. L.,Jenkins, A. J.> ;J. Diabetes Complicat.. 2013 Aug 1
Apolipoprotein-defined lipoproteins and apolipoproteins: Associations with abnormal albuminuria in type 1 diabetes in the diabetes control and complications trial/epid...
Jenkins, A. J.,Yu, J.,Alaupovic, P.,Basu, A.,Klein, R. L.,Lopes-Virella, M.,Baker, N. L.,Hunt, K. J.,Lackland, D. T.,Garvey, W. T.,Lyons, T. J.> ;J. Diabetes Complicat.. 2013 Jul 16
Premalignant lesions skew spleen cell responses to immune modulation by adipocytes.
Vielma, S. A.,Klein, R. L.,Levingston, C. A.,Young, M. R.> ;Anticancer Res.. 2013 May
Adipocytes as immune regulatory cells.
Vielma, S. A.,Klein, R. L.,Levingston, C. A.,Young, M. R.> ;Int. Immunopharmacol.. 2013 Jun
Baseline Markers of Inflammation Are Associated With Progression to Macroalbuminuria in Type 1 Diabetic Subjects.
Lopes-Virella, M. F.,Baker, N. L.,Hunt, K. J.,Cleary, P. A.,Klein, R.,Virella, G.> ;Diabetes Care. 2013 Aug
Enhanced adiponectin actions by overexpression of adiponectin receptor 1 in macrophages.
Luo, N.,Chung, B. H.,Wang, X.,Klein, R. L.,Tang, C. K.,Garvey, W. T.,Fu, Y.> ;Atherosclerosis. 2013 May
Effects of macrophage-specific adiponectin expression on lipid metabolism in vivo.
Luo, N., Wang, X., Chung, B. H., Lee, M. H., Klein, R. L., Garvey, W. T., Fu, Y.> ;Am J Physiol Endocrinol Metab. 2011 Jul
Oxidized LDL immune complexes stimulate collagen IV production in mesangial cells via Fc gamma receptors I and III.
Abdelsamie, S. A., Li, Y., Huang, Y., Lee, M. H., Klein, R. L., Virella, G., Lopes-Virella, M. F.> ;Clin Immunol. 2011 Jun
Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration.
Kopplin LJ, Igo RP, Wang Y, Sivakumaran TA, Hagstrom SA, Peachey NS, Francis PJ, Klein ML, SanGiovanni JP, Chew EY, Pauer GJT, Sturgill GM, Joshi T, Tian L, Xi Q, Henn...> ;Genes Immun.. 2010-12-01
234 citations
Blood sphingolipidomics in healthy humans: impact of sample collection methodology.
Samar M. Hammad, Jason S. Pierce, Farzan Soodavar, Kent J. Smith, Mohammed M. Al Gadban, Barbara Rembiesa, Richard L. Klein, Yusuf A. Hannun, Jacek Bielawski, Alicja B...> ;Journal of Lipid Research. 2010 Oct 1
Association of midgestation paraoxonase 1 activity and pregnancies complicated by preterm birth.
Baker, A. M., Haeri, S., Klein, R. L., Boggess, K.> ;Am J Obstet Gynecol. 2010 Sep
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Professional Memberships

American College of Surgeons - ACS
Member