RichardAlanLafayetteMD

Nephrology • Stanford, CA

Professor, Medicine - Nephrology, Stanford University Medical Center

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Office
Stanford Hospital Clinics 300 Pasteur Drive
Stanford, CA 94305
Phone(650) 723-6961
Fax(650) 725-8418
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Education & Training

Stanford UniversityFELLOWSHIP
North Shore-Long Island Jewish Health SystemRESIDENCY
New York Medical CollegeMEDICAL_SCHOOL

Certifications & Licensure

CA State Medical License 1988 - 2021
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Nephrology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013

Clinical Trials

MEmbranous Nephropathy Trial Of Rituximab Start of enrollment: 2011 Nov 01Rizk, D.,Juncos, L.,Fervenza, F.C.,Thomas, L.F.,Sussman, A.,Lafayette, R.,Aslam, N.,Green, D.,McCarthy, E.,Geetha, D.,Singh, A.,Gipson, P.,Riess, L.A.,Radhakrishnan, J.,Lasic, L.B.,Sedor, J.,Simon, J.,Rov...
Nephrotic Syndrome Study Network Start of enrollment: 2010 Apr 01Bomback, A.,Froment, A.,Sethna, C.,Lienczewski, C.C.,Harkness, C.,Gipson, D.,Rochester, D.,Kelepouris, E.,Modersitzki, F.,Orbe, I.,Vassallo, J.,LaPage, J.,Stultz, J.,Kopp, J.P.,Sedor, J.,Perumal, K.,Samba...
A Multicenter, Randomized, Prospective, Open-Label Trial of Rituximab in the Treatment of Progressive IgA Nephropathy Start of enrollment: 2009 Feb 01Canetta, P.,Fervenza, F.C.,Jennison, S.,Lafayette, R.,Nachman, P.H.,Rovin, B.H.
Randomized Open Label Study Comparing the Metabolic Control of First Kidney Transplant Recipients With Pre-Existing Type 2 Diabetes (DM) Receiving Either Prograf or Neoral as Part of a Thymoglobulin Induction, Prednisone Free and Blood Monitored Cellcept Start of enrollment: 2005 Jun 01Busque, S.,Simos, A.

Publications & Presentations

PubMed

Safety, Tolerability and Efficacy of Narsoplimab, a Novel MASP-2 Inhibitor for the Treatment of IgA Nephropathy.
Lafayette, R. A., Rovin, B. H., Reich, H. N., Tumlin, J. A., Floege, J., Barratt, J.> ;Kidney international reports. 2020 Nov 10
The longitudinal relationship between patient-reported outcomes and clinical characteristics among patients with focal segmental glomerulosclerosis in the Nephrotic Sy...
Troost, J. P., Waldo, A., Carlozzi, N. E., Murphy, S., Modersitzki, F., Trachtman, H., Nachman, P. H., Reidy, K. J., Selewski, D. T., Herreshoff, E. G., Srivastava, T....> ;Clinical kidney journal. 2020 Sep 10
Time to Initiation of Antihypertensive Therapy After Onset of Elevated Blood Pressure in Patients With Primary Proteinuric Kidney Disease.
Weaver, D. J., Waldo, A., Oh, G. J., Kamil, E. S., Elliott, M., Adler, S., Pesenson, A., Modes, M. M., Gipson, P., Lafayette, R. A., Selewski, D. T., Attalla, S. E., E...> ;Kidney medicine. 2020 Aug 1
Identifying Outcomes Important to Patients with Glomerular Disease and Their Caregivers.
Carter, S. A., Gutman, T., Logeman, C., Cattran, D., Lightstone, L., Bagga, A., Barbour, S. J., Barratt, J., Boletis, J., Caster, D., Coppo, R., Fervenza, F. C., Floeg...> ;Clinical journal of the American Society of Nephrology : CJASN. 2020 May 2
JAK-STAT Activity in Peripheral Blood Cells and Kidney Tissue in IgA Nephropathy.
Tao, J., Mariani, L., Eddy, S., Maecker, H., Kambham, N., Mehta, K., Hartman, J., Wang, W., Kretzler, M., Lafayette, R. A.> ;Clinical journal of the American Society of Nephrology : CJASN. 2020 May 2
Organ responses with daratumumab therapy in previously treated AL amyloidosis.
Chung, A., Kaufman, G. P., Sidana, S., Eckhert, E., Schrier, S. L., Lafayette, R. A., Arai, S., Witteles, R. M., Liedtke, M.> ;Blood advances. 2020 Feb 7
Facing the Vexing Problem of Recurrent FSGS after Kidney Transplantation.
Lafayette, R. A.> ;Clinical journal of the American Society of Nephrology : CJASN. 2020 Jan 30
Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy.
Fervenza, F. C., Appel, G. B., Barbour, S. J., Rovin, B. H., Lafayette, R. A., Aslam, N., Jefferson, J. A., Gipson, P. E., Rizk, D. V., Sedor, J. R., Simon, J. F., McC...> ;The New England journal of medicine. 2019 Jul 4
Standardized Outcomes in Nephrology-Glomerular Disease (SONG-GD): establishing a core outcome set for trials in patients with glomerular disease.
Carter, S. A.,Lightstone, L.,Cattran, D.,Bagga, A.,Barbour, S. J.,Barratt, J.,Boletis, J.,Caster, D.,Coppo, R.,Fervenza, F. C.,Floege, J.,Hladunewich, M.,Hogan, J. J.,...> ;Kidney Int.. 2019 May 28
Increasing Options for First-Line Therapy in Primary FSGS?
Lafayette, R. A.> ;Kidney international reports. 2019 Jan 1
A rare case of Alport syndrome, atypical hemolytic uremic syndrome and Pauci-immune crescentic glomerulonephritis.
Tao, J., Lieberman, J., Lafayette, R. A., Kambham, N.> ;BMC nephrology. 2018 Dec 14
Grading cardiac response in AL amyloidosis: implications for relapse and survival.
Eckhert, E.,Witteles, R.,Kaufman, G.,Lafayette, R.,Arai, S.,Schrier, S.,O'Shaughnessy, M.,Liedtke, M.> ;Br. J. Haematol.. 2018 Dec 21
Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study.
Selewski, D. T., Ambruzs, J. M., Appel, G. B., Bomback, A. S., Matar, R. B., Cai, Y., Cattran, D. C., Chishti, A. S., D'Agati, V. D., D'Alessandri-Silva, C. J., Gbadeg...> ;Kidney international reports. 2018 Nov 20
JAK-STAT signaling is activated in the kidney and peripheral blood cells of patients with focal segmental glomerulosclerosis.
Tao, J., Mariani, L., Eddy, S., Maecker, H., Kambham, N., Mehta, K., Hartman, J., Wang, W., Kretzler, M., Lafayette, R. A.> ;Kidney international. 2018 Aug 11
Cause of kidney disease and cardiovascular events in a national cohort of US patients with end-stage renal disease on dialysis: a retrospective analysis.
O'Shaughnessy, M. M., Liu, S., Montez-Rath, M. E., Lafayette, R. A., Winkelmayer, W. C.> ;European heart journal. 2018 Aug 8
Corticosteroids for IgA Nephropathy: TESTING for Benefit, Discovering Harm.
O'Shaughnessy, M. M., Lafayette, R. A.> ;JAMA. 2017 Aug 2
1 citation
Daratumumab yields rapid and deep hematologic responses in patients with heavily pretreated AL amyloidosis.
Kaufman, G. P., Schrier, S. L., Lafayette, R. A., Arai, S., Witteles, R. M., Liedtke, M.> ;Blood. 2017 Jun 16
Validating identification of patients with small vessel vasculitis, with or without renal involvement, using administrative healthcare records.
O'Shaughnessy, M. M., Cheng, X. S., Montez-Rath, M. E., Lafayette, R. A., Winkelmayer, W. C.> ;Clinical nephrology. 2017 Jan 20
12 citations
A Randomized, Controlled Trial of Rituximab in IgA Nephropathy with Proteinuria and Renal Dysfunction.
Lafayette, R. A., Canetta, P. A., Rovin, B. H., Appel, G. B., Novak, J., Nath, K. A., Sethi, S., Tumlin, J. A., Mehta, K. R., Hogan, M. C., Erickson, S. B., Julian, B....> ;Journal of the American Society of Nephrology : JASN. 2016 Nov 9
2 citations
Endoplasmic Reticulum Stress Predicts Clinical Response to Cyclosporine Treatment in Primary Membranous Nephropathy.
Tao, J., Zhang, W., Wen, Y., Sun, Y., Chen, L., Li, H., Li, M., Li, X., Lafayette, R. A., Li, X.> ;American journal of nephrology. 2016 May 12
8 citations
Complete Remission in the Nephrotic Syndrome Study Network.
Gipson, D. S., Troost, J. P., Lafayette, R. A., Hladunewich, M. A., Trachtman, H., Gadegbeku, C. A., Sedor, J. R., Holzman, L. B., Moxey-Mims, M. M., Perumal, K., Kask...> ;Clinical journal of the American Society of Nephrology : CJASN. 2015 Dec 15
Differences in initial treatment modality for end-stage renal disease among glomerulonephritis subtypes in the USA.
O'Shaughnessy, M. M., Montez-Rath, M. E., Lafayette, R. A., Winkelmayer, W. C.> ;Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2015 Nov 28
Clinicopathological features of membranoproliferative glomerulonephritis under a new classification.
Nargund, P., Kambham, N., Mehta, K. R., Lafayette, R. A.> ;Clinical nephrology. 2015 Oct 8
Mapping novel immunogenic epitopes in IgA nephropathy.
Woo, S. H., Sigdel, T. K., Van T Dinh, Vu, M., Sarwal, M. M., Lafayette, R. A.> ;Clinical journal of the American Society of Nephrology : CJASN. 2014 Dec 30
2 citations
Incidence and relevance of proteinuria in bevacizumab-treated patients: pooled analysis from randomized controlled trials.
Lafayette, R. A., McCall, B., Li, N., Chu, L., Werner, P., Das, A., Glassock, R. J.> ;American journal of nephrology. 2014 Jul 26
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Abstracts/Posters

Facing the Vexing Problem of Recurrent FSGS After Kidney Transplantation
Richard Lafayette, MD, American Society of Nephrology, Orlando, FL, 12/7/2019
Facing the Vexing Problem of Recurrent FSGS After Kidney Transplantation
Richard Lafayette, MD, American Society of Nephrology, Orlando, FL, 12/7/2019

Press Mentions

Omeros Finalizes with FDA Clinical Plan for OMS721 Approval in IgA NephropathyJanuary 17, 2019 21:17
Omeros Establishes Independent Academic Leadership Committee for Its OMS721 Phase 3 Clinical Program in IgA NephropathyJanuary 13, 2019 08:20