RichardAlanShapiroMD

PubMed

• Redox-dependent regulation of hepatocyte absent in melanoma 2 inflammasome activation in sterile liver injury in mice.
  Sun Q, Loughran P, Shapiro R, Shrivastava IH, Antoine DJ, Li T, Yan Z, Fan J, Billiar TR, Scott MJ> ;Hepatology. 2017-01-01
• Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires CD14.
  Kim, S.,Kim, S. Y.,Pribis, J. P.,Lotze, M.,Mollen, K. P.,Shapiro, R.,Loughran, P.,Scott, M. J.,Billiar, T. R.> ;Mol. Med.. 2013
• Cellular specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury.
  Nace, G. W.,Huang, H.,Klune, J. R.,Eid, R. E.,Rosborough, B. R.,Korff, S.,Li, S.,Shapiro, R. A.,Stolz, D. B.,Sodhi, C. P.,Hackam, D. J.,Geller, D. A.,Billiar, T. R.,Ts...> ;Hepatology. 2013 Jul
• High mobility group Box 1 inhibits human pulmonary artery endothelial cell migration via a Toll-like receptor 4- and interferon response factor 3-dependent mechanism(s).
  Bauer, E. M.,Shapiro, R.,Billiar, T. R.,Bauer, P. M.> ;J Biol Chem. 2013 Jan 11
• High Mobility Group Box 1 Contributes to the Pathogenesis of Experimental Pulmonary Hypertension via Activation of Toll-like Receptor 4.
  Bauer, E. M.,Shapiro, R.,Zheng, H.,Ahmad, F.,Ishizawar, D.,Comhair, S. A.,Erzurum, S. C.,Billiar, T. R.,Bauer, P. M.> ;Mol Med. 2012
• Models of lower extremity damage in mice: time course of organ damage and immune response.
  Menzel, C. L., Pfeifer, R., Darwiche, S. S., Kobbe, P., Gill, R., Shapiro, R. A., Loughran, P., Vodovotz, Y., Scott, M. J., Zenati, M. S., Billiar, T. R., Pape, H. C.> ;J Surg Res. 2011 Apr
• Extracellular high mobility group box-1 (HMGB1) inhibits enterocyte migration via activation of Toll-like receptor-4 and increased cell-matrix adhesiveness.
  Dai, S., Sodhi, C., Cetin, S., Richardson, W., Branca, M., Neal, M. D., Prindle, T., Ma, C., Shapiro, R. A., Li, B., Wang, J. H., Hackam, D. J.> ;J Biol Chem. 2010 Feb 12
• Toll-like receptor-4 inhibits enterocyte proliferation via impaired beta-catenin signaling in necrotizing enterocolitis.
  Sodhi, C. P., Shi, X. H., Richardson, W. M., Grant, Z. S., Shapiro, R. A., Prindle, T., Branca, M., Russo, A., Gribar, S. C., Ma, C., Hackam, D. J.> ;Gastroenterology. 2010 Jan 01
• Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism.
  Scott, M. J., Liu, S., Shapiro, R. A., Vodovotz, Y., Billiar, T. R.> ;Hepatology. 2009 May
• Calcium/calmodulin-dependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages.
  Zhang, X., Wheeler, D., Tang, Y., Guo, L., Shapiro, R. A., Ribar, T. J., Means, A. R., Billiar, T. R., Angus, D. C., Rosengart, M. R.> ;J Immunol. 2008 Oct 01
• Changes in FADD levels, distribution, and phosphorylation in TNFalpha-induced apoptosis in hepatocytes is caspase-3, caspase-8 and BID dependent.
  Zhang, X., Vallabhaneni, R., Loughran, P. A., Shapiro, R., Yin, X. M., Yuan, Y., Billiar, T. R.> ;Apoptosis. 2008 Aug
• Nitric oxide-induced inhibition of smooth muscle cell proliferation involves S-nitrosation and inactivation of RhoA.
  Zuckerbraun, B. S., Stoyanovsky, D. A., Sengupta, R., Shapiro, R. A., Ozanich, B. A., Rao, J., Barbato, J. E., Tzeng, E.> ;Am J Physiol Cell Physiol. 2007 Feb
• Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells.
  Song, R., Zhou, Z., Kim, P. K., Shapiro, R. A., Liu, F., Ferran, C., Choi, A. M., Otterbein, L. E.> ;J Biol Chem. 2004 Oct 22
• Adenovirus-mediated nitric oxide synthase gene transfer.
  Raman, K. G., Shapiro, R. A., Tzeng, E., Kibbe, M. R.> ;Methods Mol Biol. 2004
• RhoA influences the nuclear localization of extracellular signal-regulated kinases to modulate p21Waf/Cip1 expression.
  Zuckerbraun, B. S., Shapiro, R. A., Billiar, T. R., Tzeng, E.> ;Circulation. 2003 Aug 19
• Role of toll-like receptors in changes in gene expression and NF-kappa B activation in mouse hepatocytes stimulated with lipopolysaccharide.
  Liu, S., Gallo, D. J., Green, A. M., Williams, D. L., Gong, X., Shapiro, R. A., Gambotto, A. A., Humphris, E. L., Vodovotz, Y., Billiar, T. R.> ;Infect Immun. 2002 Jul
• Isolation and enzymatic activity of angiogenin.
  Riordan JF, Shapiro R> ;Methods Mol. Biol.. 2001-01-01
• Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes.
  Jaiswal M, LaRusso NF, Shapiro RA, Billiar TR, Gores GJ> ;Gastroenterology. 2001-01-01
• CD14 employs hydrophilic regions to "capture" lipopolysaccharides.
  Cunningham MD, Shapiro RA, Seachord C, Ratcliffe K, Cassiano L, Darveau RP> ;J. Immunol.. 2000-03-15
• Potent inhibition of mammalian ribonucleases by 3', 5'-pyrophosphate-linked nucleotides.
  Russo N, Shapiro R> ;J. Biol. Chem.. 1999-05-21
• Expression of CD14 by hepatocytes: upregulation by cytokines during endotoxemia.
  Liu S, Khemlani LS, Shapiro RA, Johnson ML, Liu K, Geller DA, Watkins SC, Goyert SM, Billiar TR> ;Infect. Immun.. 1998-11-01
• Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene.
  Taylor BS, de Vera ME, Ganster RW, Wang Q, Shapiro RA, Morris SM, Billiar TR, Geller DA> ;J. Biol. Chem.. 1998-06-12
• Cloning and expression of human inducible nitric oxide synthase.
  Johnson ML, Shapiro RA, Billiar TR> ;Methods Mol. Biol.. 1998-01-01
• Interaction of heparin with human angiogenin.
  Soncin F, Strydom DJ, Shapiro R> ;J. Biol. Chem.. 1997-04-11
• Identification of CD14 residues involved in specific lipopolysaccharide recognition.
  Shapiro RA, Cunningham MD, Ratcliffe K, Seachord C, Blake J, Bajorath J, Aruffo A, Darveau RP> ;Infect. Immun.. 1997-01-01
• Join now to see all