RichardWSmallingMD

Cardiology • Houston, TX

Adult Congenital Heart Disease, Interventional Cardiology

Professor, Internal Medicine, University of Texas Medical School, Houston.

Join to view full profile

Dr. Smalling is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Smalling's full profile

Already have an account?

Office
6410 Fannin St
Suite 600
Houston, TX 77030
Phone+1 713-500-8828

Fax+1 713-500-6560
Is this information wrong?

Education & Training

University of California (San Diego) Medical CenterFellowship, Cardiovascular Disease, 1978 - 1981
University of California (San Diego) Medical CenterResidency, Internal Medicine, 1975 - 1978
McGovern Medical School at UTHealthClass of 1975

Certifications & Licensure

TX State Medical License 1975 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Master Interventionalist - MSCAI Society of Cardiac Angiography and Interventions
James D. Woods Distinguished Chair in Cardiovascular Medicine UTHealth/McGovern Medical School
America's Top Doctors Castle Connolly, 2002-2014
Top Doctors:SE Texas Castle Connolly, 2013
Fellow (FACC) American College of Cardiology
Whos Who in Medicine and Healthcare Marquis Whos Who
Top MD Consumers Checkbook
Super Doctor SuperDoctors.com
Join now to see all

Clinical Trials

Prostaglandin E1 (Liprostin) Treatment With Lower Limb Angioplasty for Peripheral Arterial Occlusive Disease Start of enrollment: 2003 Feb 01
Unknown status
Phase 2
Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization Start of enrollment: 2003 Sep 01
Completed
Phase 4
A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Disease Start of enrollment: 2002 Nov 01
Completed
Phase 4
Feasibility Study of a Percutaneous Mitral Valve Repair System. Start of enrollment: 2003 Jul 01
Completed
Phase 1, Phase 2
Patent Foramen Ovale Closure or Medical Therapy After Stroke - RESPECT Trial Start of enrollment: 2003 Aug 01
Completed
Not Applicable
Counterpulsation Reduces Infarct Size Pre-PCI for AMI Start of enrollment: 2008 Dec 01
Completed
Phase 4
PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - XT Intermediate and High Risk Start of enrollment: 2011 Mar 01
Completed
Not Applicable
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CAS Start of enrollment: 2012 Aug 01
Active, not recruiting
Not Applicable
EVEREST II Pivotal Study High Risk Registry (HRR) Start of enrollment: 2007 Feb 01
Completed
Not Applicable
The REFLECT Trial: Cerebral Protection to Reduce Cerebral Embolic Lesions After Transcatheter Aortic Valve Implantation Start of enrollment: 2016 Jun 01
Completed
Not Applicable
PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis Start of enrollment: 2016 Mar 01
Active, not recruiting
Not Applicable
PARTNER 3 Trial - Aortic Valve-in-Valve Start of enrollment: 2017 Jan 05
Recruiting
Not Applicable
PARTNER 3 Trial - Mitral Valve in Valve Start of enrollment: 2018 Feb 01
Active, not recruiting
Not Applicable
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. Start of enrollment: 2017 Oct 23
Recruiting
Not Applicable
AMPLATZER PFO Occluder Post Approval Study Start of enrollment: 2018 Jan 31
Recruiting
Not Applicable
REPRISE IV: LOTUS Edge Valve System in Intermediate Surgical Risk Subjects Start of enrollment: 2019 Jan 14
Terminated
Not Applicable
Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial Start of enrollment: 2018 Nov 30
Recruiting
Not Applicable
MitraClip EXPAND G4 Study Start of enrollment: 2020 Jan 17
Active, not recruiting
MitraClip REPAIR MR Study Start of enrollment: 2020 Jul 21
Recruiting
Not Applicable
Join now to see all

Publications & Presentations

PubMed

Transmembrane stem factor nanodiscs enhanced revascularization in a hind limb ischemia model in diabetic, hyperlipidemic rabbits.
Takematsu, E., Massidda, M., Howe, G., Goldman, J., Felli, P., Mei, L., Callahan, G., Sligar, A., Baker, A., Smalling, R.> ;Scientific Reports. 2024 Jan 29
6 citations
Coronary flow capacity and survival prediction after revascularization: physiological basis and clinical implications.
Gould, K., Johnson, N., Roby, A., Bui, L., Kitkungvan, D., Patel, M., Nguyen, T., Kirkeeide, R., Haynie, M., Arain, S., Charitakis, K., Dhoble, A., Smalling, R., Nasci...> ;European Heart Journal. 2024 Jan 14
6 citations
1-Year Outcomes of Transcatheter Edge-to-Edge Repair in Anatomically Complex Degenerative Mitral Regurgitation Patients.
Smith, R., Lim, D., Gillam, L., Zahr, F., Chadderdon, S., Rassi, A., Makkar, R., Goldman, S., Rudolph, V., Hermiller, J., Kipperman, R., Dhoble, A., Smalling, R., Lati...> ;JACC. Cardiovascular Interventions. 2023 Dec 11
Heart Brain Clinic: An Integrated Approach to Stroke Care.
Syed Kalimullah S Qadri, Kathleen Tulod, Maria Jamilla Lacap, Munachi Okpala, Muhammad Bilal Tariq, Anjail Sharrief, Abhijeet Dhoble, Sidhanta Gurung, Bharti Manwani, ...> ;Neurology. Clinical Practice. 2023 Dec 1
5 citations
5-Year Prospective Evaluation of Mitral Valve-in-Valve, Valve-in-Ring, and Valve-in-MAC Outcomes: MITRAL Trial Final Results.
Mayra E Guerrero, Mackram F Eleid, Dee Dee Wang, Amit Pursnani, Susheel K Kodali, Isaac George, Igor Palacios, Hyde Russell, Raj R Makkar, Saibal Kar, Lowell F Satler,...> ;JACC. Cardiovascular Interventions. 2023 Sep 25
5 citations
Outcomes of transcatheter aortic valve replacement in patients with cardiogenic shock.
Kashish Goel, Pinak Shah, Brandon M Jones, Ethan Korngold, Anju Bhardwaj, Biswajit Kar, Colin Barker, Molly Szerlip, Richard Smalling, Abhijeet Dhoble> ;European Heart Journal. 2023 Sep 1
3 citations
Syndecan-4 proteoliposomes enhance revascularization in a rabbit hind limb ischemia model of peripheral ischemia.
Andrew D Sligar, Gretchen Howe, Julia Goldman, Patricia Felli, Almudena Gómez-Hernández, Eri Takematsu, Austin Veith, Shubh Desai, William J Riley, Rohan Singeetham, L...> ;Acta Biomaterialia. 2023 Sep 1
5 citations
Interplay of hypoxia-inducible factors and oxygen therapy in cardiovascular medicine.
Yafen Liang, Wei Ruan, Yandong Jiang, Richard Smalling, Xiaoyi Yuan, Holger K Eltzschig> ;Nature Reviews. Cardiology. 2023 Nov 1
19 citations
Transcatheter Edge-to-Edge Repair in Patients With Anatomically Complex Degenerative Mitral Regurgitation.
Hausleiter, J., Lim, D., Gillam, L., Zahr, F., Chadderdon, S., Rassi, A., Makkar, R., Goldman, S., Rudolph, V., Hermiller, J., Kipperman, R., Dhoble, A., Smalling, R.,...> ;Journal of the American College of Cardiology. 2023 Feb 7
9 citations
Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure.
Jean-Louis Mas, Jeffrey L Saver, Scott E Kasner, Jason Nelson, John D Carroll, Gilles Chatellier, Geneviève Derumeaux, Anthony J Furlan, Howard C Herrmann, Peter Jüni,...> ;JAMA Neurology. 2022 Nov 1
70 citations
Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke.
David M Kent, Jeffrey L Saver, Scott E Kasner, Jason Nelson, John D Carroll, Gilles Chatellier, Geneviève Derumeaux, Anthony J Furlan, Howard C Herrmann, Peter Jüni, J...> ;JAMA. 2021 Dec 14
8 citations
Catastrophic Cardiac Events during Transcatheter Aortic Valve Replacement
Yafen Liang, Abhijeet Dhoble, Adarsh Pakanati, Yelin Zhao, Felix Kork, Wei Ruan, Travis H. Markham, Richard W. Smalling, Prakash Balan, Anthony L. Estrera, Tom C. Nguy...> ;The Canadian Journal of Cardiology. 2021 May 13
24 citations
Prospective Evaluation of TMVR for Failed Surgical Annuloplasty Rings: MITRAL Trial Valve-in-Ring Arm 1-Year Outcomes.
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;JACC. Cardiovascular Interventions. 2021 Apr 26
5 citations
Initial experience with the fourth generation MitraClip™: Outcomes, procedural aspects, and considerations for device selection.
Enrique Garcia-Sayan, Deepa Raghunathan, Flora M. Li, Abhijeet Dhoble, Richard Sheu, Srdjan Jelacic, Mark Reisman, Richard W. Smalling, G. Burkhard Mackensen> ;Catheterization and Cardiovascular Interventions. 2021 Apr 13
3 citations
Reinventing the displacement left ventricular assist device in the continuous-flow era: TORVAD, the first toroidal-flow left ventricular assist device.
Carlo R. Bartoli, Jeffrey R. Gohean, Richard W. Smalling> ;Annals of Cardiothoracic Surgery. 2021 Mar 1
Pre-transfer/PCI with ticagrelor and heparin administration in STEMI patients may be beneficial but should we do more?
Richard W. Smalling> ;Catheterization and Cardiovascular Interventions. 2021 Mar 1
Decreasing Rates of Acute Kidney Injury After Percutaneous Coronary Interventions Through Education and Standardized Order Sets in a Large Tertiary Teaching Center.
Adrian daSilva-deAbreu, Sidhanta Gurung, William Bracamonte-Baran, Patrick Byrnes, Prakash Balan, Kevin Finkel, Richard W. Smalling, H. Vernon Anderson, Salman Arain> ;Current Problems in Cardiology. 2021 Mar 1
5 citations
Trends and Impact of the Use of Mechanical Circulatory Support for Cardiogenic Shock Secondary to Takotsubo Cardiomyopathy
Steven Napierkowski, Upasana Banerjee, H Vernon Anderson, Konstantinos Charitakis, Richard W. Smalling, Abhijeet Dhoble> ;The American Journal of Cardiology. 2021 Jan 15
101 citations
One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart Valve
Brian Whisenant, Samir R. Kapadia, Mackram F. Eleid, Susheel Kodali, James M. McCabe, Amar Krishnaswamy, Michael Morse, Richard W. Smalling, Mark Reisman, Michael J. M...> ;JAMA Cardiology. 2020 Nov 1
29 citations
Risk of Paradoxical Embolism (RoPE)-Estimated Attributable Fraction Correlates With the Benefit of Patent Foramen Ovale Closure: An Analysis of 3 Trials.
David M. Kent, Jeffrey L. Saver, Robin Ruthazer, Anthony J. Furlan, Mark Reisman, John D. Carroll, Richard W. Smalling, Peter Jüni, Heinrich Mattle, Bernhard Meier, Da...> ;Stroke. 2020 Sep 14
4 citations
Outcomes of Patients Undergoing Transcatheter Aortic Valve Implantation With Incidentally Discovered Masses on Computed Tomography.
Amaninderapal S. Ghotra, Dominique J. Monlezun, David Boone, Robin Jacob, Kassra Poosti, Catalin Loghin, Enrique Garcia-Sayan, Sarah Jean Johnson, Yelin Zhao, Prakash ...> ;The American Journal of Cardiology. 2020 Jul 11
2 citations
Rates, predictors, and outcomes of early readmissions after tricuspid valve surgery.
Abhijeet Dhoble, Shareez Peerbhai, Yelin Zhao, Pimprapa Vejpongsa, Enrique Garcia-Sayan, Richard W. Smalling, Anthony L. Estrera, Tom C. Nguyen> ;Journal of Cardiac Surgery. 2020 Jul 11
1 citations
TGFBR1 Rare Variant Associated With Thoracic Aortic Aneurysm, Double Chamber Left Ventricle, Coronary Anomaly, and Inducible Ventricular Tachycardia.
Katia Bravo-Jaimes, Naddi B. Marah, Deepa Raghunathan, Steven Napierkowski, Ijeoma A. Ekeruo, Danai Kitkungvan, Dianna M. Milewicz, Richard W. Smalling, Siddharth K. P...> ;Circulation. Cardiovascular Imaging. 2020 Jun 1
9 citations
First-in-Human Report of MitraClip G4 Implantation for Torrential Tricuspid Regurgitation and Severe Secondary Mitral Regurgitation
Deepa Raghunathan, Enrique Garcia-Sayan, Michael Schechter, Steven Napierkowski, Abhijeet Dhoble, Richard W. Smalling> ;JACC. Cardiovascular Interventions. 2020 Jul 13
8 citations
Validation of scoring system predicting permanent pacemaker implantation after transcatheter aortic valve replacement
Poojita Shivamurthy, Pimprapa Vejpongsa, Sidhanta Gurung, Robin Jacob, Yelin Zhao, H. Vernon Anderson, Prakash Balan, Tom C. Nguyen, Anthony L. Estrera, Anne H. Doughe...> ;Pacing and Clinical Electrophysiology. 2020 Apr 9
Join now to see all

Journal Articles

One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart Valve
Brian Whisenant, Samir R Kapadia, Mackram F Eleid, James M Mccabe, Amar Krishnaswamy, Richard W Smalling, Charanjit S Rihal, Raj R Makkar, JAMA Cardiology
Regional Artery Specific Thresholds of Quantitative Myocardial Perfusion by PET Associated with Reduced MI and Death After Revascularization in Stable CAD
Mohammad Madjid, Igor Gregoric, Richard W Smalling, Nils P Johnson, Monica B Patel, Salman Arain, David McPherson, Pranav Loyalka, Hazim Safi, Anthony Estrera, Journal of Nuclear Medicine

Authored Content

One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart ValveJuly 2020
One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart ValveJuly 2020

Press Mentions

UTHealth Physicians Give Track Star New Lease on Life with PFO Closure ProcedureSeptember 14th, 2017
UTHealth Leads Study of Device for Minimally Invasive Repair of Aortic Aneurysms (The University of Texas Health Science Center at Houston)June 8th, 2016
Crozer-Keystone Introduces Evidence-Based Program for Heart Valve Disorders (Crozer-Keystone Health System)June 8th, 2016
Join now to see all