RishiRameshLullaMD

Pediatric Hematology & Oncology • Providence, RI

Pediatric Neuro-Oncology

Associate Professor in Pediatrics The Warren Alpert Medical School at Brown University

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Office
593 Eddy St
Providence, RI 02903
Phone+1 401-444-5171
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Education & Training

McGaw Medical Center of Northwestern UniversityFellowship, Pediatric Hematology/Oncology, 2007 - 2010
McGaw Medical Center of Northwestern UniversityResidency, Pediatrics, 2003 - 2007
Boston University School of MedicineClass of 2003

Certifications & Licensure

RI State Medical License 2018 - 2024
IL State Medical License 2003 - 2020
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Blood and Cerebrospinal Fluid for Pediatric Brain Tumor Research Start of enrollment: 2011 Jul 01
Completed
Longitudinal Study of Biomarkers Start of enrollment: 2011 Dec 01
Unknown status
Posterior Fossa Mutism on Quality of Life Start of enrollment: 2011 Jul 01
Completed
Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma Start of enrollment: 2020 Feb 20
Recruiting
Phase 2
Circulating microRNAs as Disease Markers in Pediatric Cancers Start of enrollment: 2010 Mar 01
Unknown status
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Vorinostat, temozolomide or bevacizumab with irradiation and maintenance BEV/TMZ in pediatric high-grade glioma: A Children's Oncology Group Study.
Rishi R Lulla, Allen Buxton, Mark D Krailo, Margot A Lazow, Daniel R Boue, James L Leach, Tong Lin, James I Geller, Shiva Senthil Kumar, Marina N Nikiforova, Uma Chand...> ;Neuro-Oncology Advances. 2024 Mar 14
Anti-SARS-CoV-2 Monoclonal Antibodies in Pediatrics: Statewide Experience in Rhode Island.
Osama Ibrahim, Winston McCormick, Kristen Ferlisi, Shannon Baker, Rishi Lulla, Michael Koster> ;Rhode Island Medical Journal. 2023 Aug 1
7 citations
OpenPBTA: The Open Pediatric Brain Tumor Atlas.
Joshua A Shapiro, Krutika S Gaonkar, Stephanie J Spielman, Candace L Savonen, Chante J Bethell, Run Jin, Komal S Rathi, Yuankun Zhu, Laura E Egolf, Bailey K Farrow, Da...> ;Cell Genomics. 2023 Jul 12
2 citations
ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma.
Anne-Florence Blandin, Ross Giglio, Maya Srikanth Graham, Guadalupe Garcia, Seth Malinowski, Jared K Woods, Shakti Ramkissoon, Lori Ramkissoon, Frank Dubois, Kathleen ...> ;Clinical Cancer Research. 2023 Jul 14
18 citations
The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.
Franson, A. (., Franson, A. (., Jena V Lilly, Jo Lynne Rokita, Jennifer L Mason, Tatiana Patton, Stephanie Stefankiewiz, David Higgins, Gerri Trooskin, Carina A Larouc...> ;Neoplasia. 2023 Jan 1
Novel combination of imipridones and histone deacetylase inhibitors demonstrate cytotoxic effect through integrated stress response in pediatric solid tumors.
Honeyman, J., Zhang, J., Lin, C., Sharma, A., Zhou, L., Oliveira, J., Tapinos, N., Prabhu, V., Chang, W., Lulla, R., El-Deiry, W.> ;American Journal of Cancer Research. 2023 Jan 1
Comparative flow cytometry-based immunophenotyping analysis of peripheral blood leukocytes before and after fixation with paraformaldehyde.
E Vistica Sampino, J Morgan, A Chorzalska, L Nguyen, C Yu, A Rodriguez, M Pardo, D Bonal, O Liang, M Kim, R De Vito, R R Lulla, P M Dubielecka> ;Journal of Immunological Methods. 2022 Dec 1
1 citations
Activating BRAF G469A Missense Mutation in a Pediatric Patient With High-Grade Glioma.
Adam Kronish, Bradley DeNardo, Colin Kanach, Rishi R Lulla> ;Journal of Neuropathology and Experimental Neurology. 2021 Dec 29
22 citations
EZH2i EPZ-6438 and HDACi vorinostat synergize with ONC201/TIC10 to activate integrated stress response, DR5, reduce H3K27 methylation, ClpX and promote apoptosis of mu...
Yiqun Zhang, Lanlan Zhou, Howard Safran, Robyn Borsuk, Rishi Lulla, Nikos Tapinos, Attila A. Seyhan, Wafik S. El-Deiry> ;Neoplasia. 2021 Jul 8
34 citations
Standardization of the liquid biopsy for pediatric diffuse midline glioma using ddPCR.
Daphne Li, Erin R Bonner, Kyle Wierzbicki, Eshini Panditharatna, Tina Huang, Rishi Lulla, Sabine Mueller, Carl Koschmann, Javad Nazarian, Amanda Saratsis> ;Scientific Reports. 2021 Mar 3
9 citations
Potent preclinical sensitivity to imipridone-based combination therapies in oncohistone H3K27M-mutant diffuse intrinsic pontine glioma is associated with induction of ...
Robyn Borsuk, Lanlan Zhou, Wen-I Chang, Yiqun Zhang, Aditi Sharma, Varun V. Prabhu, Nikos Tapinos, Rishi Lulla, Wafik S. El-Deiry> ;American Journal of Cancer Research. 2021 Jan 1
57 citations
Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma
Sabine Mueller, Jared Taitt, Javier Villanueva-Meyer, Erin R Bonner, Takahide Nejo, Rishi Lulla, Stewart Goldman, Anu Banerjee, Susan N. Chi, Nicholas S Whipple, John ...> ;The Journal of Clinical Investigation. 2020 Dec 1
22 citations
Pediatric high-grade glioma resources from the Children's Brain Tumor Tissue Consortium
Heba Ijaz, Mateusz Koptyra, Krutika S. Gaonkar, Jo Lynne Rokita, Valerie Baubet, Lamiya Tauhid, Yuankun Zhu, Miguel A. Brown, Gonzalo Lopez, Bo Zhang, Sharon J. Diskin...> ;Neuro-Oncology. 2020 Jan 11
43 citations
Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma
Hiroaki Katagi, Nundia Louis, Dusten Unruh, Takahiro Sasaki, Xingyao He, Ali Zhang, Quanhong Ma, Andrea Piunti, Yosuke Shimazu, Jonathan B. Lamano, Angel M. Carcaboso,...> ;Clinical Cancer Research. 2019 Sep 15
43 citations
Improved neuropsychological outcomes following proton therapy relative to X-ray therapy for pediatric brain tumor patients.
Jeffrey P. Gross, Stephanie K Powell, Frank Zelko, William F. Hartsell, Stewart Goldman, Jason Fangusaro, Rishi Lulla, Natasha Pillay Smiley, John Han Chih Chang, Vina...> ;Neuro-Oncology. 2019 Jul 11
Correction: Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diag...
Tina Huang, Roxanna M. Garcia, Jin Qi, Rishi Lulla, Craig Horbinski, Amir Behdad, Nitin R. Wadhwani, Ali Shilatifard, Charles David James, Amanda Saratsis> ;Oncotarget. 2019 Apr 12
16 citations
Transcriptional repressor REST drives lineage stage–specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma
Tara Dobson, Rong-Hua Tao, Jyothishmathi Swaminathan, Shinji Maegawa, Shavali Shaik, Javiera Bravo-Alegria, Ajay Sharma, Bridget Kennis, Yanwen Yang, Keri Callegari, A...> ;Science Signaling. 2019 Jan 22
16 citations
Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and cl...
Tina Huang, Roxanna Garcia, Jin Qi, Rishi Lulla, Craig Horbinski, Amir Behdad, Nitin Wadhwani, Ali Shilatifard, Charles James, Amanda M Saratsis> ;Oncotarget. 2018 Dec 14
Primary Central Nervous System Malignant Melanoma in Children: A Case Series and Review of the Literature
Daniel K Choi, Natasha Pillay-Smiley, Sarah Marzec, Nitin R. Wadhwani, Arthur J. DiPatri, Tadanori Tomita, Rishi Lulla> ;Journal of Pediatric Hematology/oncology. 2018 Nov 1
12 citations
REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature.
Shavali Shaik, Bridget Kennis, Shinji Maegawa, Keri Schadler, Yang Yanwen, Keri Callegari, Rishi Lulla, Stewart Goldman, Javad Nazarian, Veena Rajaram, Jason Fangusaro...> ;Oncotarget. 2018 Jan 1
11 citations
Blood-brain barrier–adapted precision medicine therapy for pediatric brain tumors
Bernard L. Marini, Lydia L. Benitez, Andrew H. Zureick, Ralph Salloum, Angela C. Gauthier, Julia Brown, Yi-Mi Wu, Dan R. Robinson, Chandan Kumar, Robert J. Lonigro, Pa...> ;Translational Research. 2017 Oct 1
9 citations
Bumps in the Road: Panniculitis in Children and Adolescents Treated with Vemurafenib
Nika Finelt, Rishi Lulla, Hector Melin-Aldana, Jennifer Shuley Ruth, Frank Y. Lin, Jack M. Su, M.P.H. Crystal Y. Pourciau M.D., Raegan D. Hunt, Brandi M. Kenner-Bell> ;Pediatric Dermatology. 2017 May 1
111 citations
Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma.
Tina Huang, Andrea Piunti, Rishi Lulla, Jin Qi, Craig Horbinski, Tadanori Tomita, C. David James, Ali Shilatifard, Amanda Saratsis> ;Acta Neuropathologica Communications. 2017 Apr 17
272 citations
Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas
Andrea Piunti, Rintaro Hashizume, Marc A. Morgan, Elizabeth T. Bartom, Craig Horbinski, Stacy A. Marshall, Emily J. Rendleman, Quanhong Ma, Yoh Hei Takahashi, Ashley R...> ;Nature Medicine. 2017 Feb 27
166 citations
Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors
Jonathon Torchia, Brian Golbourn, Shengrui Feng, King Ching Ho, Patrick Sin-Chan, Alexandre Vasiljevic, Joseph D. Norman, Paul Guilhamon, Livia Garzia, Natalia R. Agam...> ;Cancer Cell. 2016 Dec 12
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Press Mentions

Reed Joins Hasbro Children’s Hospital & American Cancer Society to Celebrate Childhood Cancer STAR Reauthorization Act Being Signed into LawJanuary 10th, 2023
‘Kind of Scary’: Amoxicillin Shortage Has Some Parents PanickingNovember 19th, 2022
Born with a Rare Brain Tumor, ‘Miracle Child’ Matthew Erickson Turns 10, Against All Odds. ‘I’m a Pretty Lucky Guy.’February 19th, 2022
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Hospital Affiliations

Rhode Island HospitalProvidence, Rhode Island