Robert AEdwardsMD

PubMed

• Antiviral and Anti-Inflammatory Therapeutic Effect of RAGE-Ig Protein against Multiple SARS-CoV-2 Variants of Concern Demonstrated in K18-hACE2 Mouse and Syrian Golden...
  Dhanushkodi, N., Prakash, S., Quadiri, A., Zayou, L., Srivastava, R., Shaik, A., Suzer, B., Ibraim, I., Landucci, G., Tifrea, D., Singer, M., Jamal, L., Vahed, H., Bro...> ;Journal of Immunology. 2024 Feb 15
• High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4and CD8memory T cells are associated with protection from symptomatic and fat...
  Pierre-Gregoire Coulon, Swayam Prakash, Nisha R Dhanushkodi, Ruchi Srivastava, Latifa Zayou, Delia F Tifrea, Robert A Edwards, Cesar J Figueroa, Sebastian D Schubl, La...> ;Frontiers in Immunology. 2024 Jan 1
• Cross-protection induced by highly conserved human B, CD4, and CD8T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-Co...
  Swayam Prakash, Nisha R Dhanushkodi, Latifa Zayou, Izabela Coimbra Ibraim, Afshana Quadiri, Pierre Gregoire Coulon, Delia F Tifrea, Berfin Suzer, Amin Mohammed Shaik, ...> ;Frontiers in Immunology. 2024 Jan 1
• 1 citations
  Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis.
  Katrina T Evans, Kerrigan Blake, Aaron Longworth, Morgan A Coburn, Jacob Insua-Rodríguez, Timothy P McMullen, Quy H Nguyen, Dennis Ma, Tatyana Lev, Grace A Hernandez, ...> ;Nature Cell Biology. 2023 Dec 1
• Dual roles of myocardial mitochondrial AKT on diabetic cardiomyopathy and whole body metabolism.
  Yu-Han Chen, Albert P Ta, Yumay Chen, Hsiao-Chen Lee, Wenjun Fan, Phang-Lang Chen, Maria C Jordan, Kenneth P Roos, Grant R MacGregor, Qin Yang, Robert A Edwards, Junfe...> ;Cardiovascular Diabetology. 2023 Oct 27
• 7 citations
  The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress.
  Gayoung Seo, Clinton Yu, Han Han, Li Xing, Rebecca Elizabeth Kattan, Jeongmin An, Amrutha Kizhedathu, Bing Yang, Annabella Luo, Abigail L Buckle, Delia Tifrea, Robert ...> ;Molecular Cell. 2023 Sep 7
• Autopsy findings from patients diagnosed with COVID-19 demonstrate unique morphological patterns in bone marrow and lymph node.
  Ali AlJabban, Mark G Evans, Geoffrey G Fell, Jack P Guccione, Robert A Edwards, Geraldine S Pinkus, Robert F Padera, Olga Pozdnyakova, Annette S Kim> ;Journal of Clinical Pathology. 2023 Jun 8
• 2 citations
  Cross-Protection Induced by Highly Conserved Human B, CD4and CD8T Cell Epitopes-Based Coronavirus Vaccine Against Severe Infection, Disease, and Death Caused by Multip...
  Swayam Prakash, Nisha R Dhanushkodi, Latifa Zayou, Izabela Coimbra Ibraim, Afshana Quadiri, Pierre Gregoire Coulon, Delia F Tifrea, Berfin Suzler, Mohamed Amin, Amruth...> ;Biorxiv. 2023 May 24
• 1 citations
  Risk factors for SARS-CoV-2 seropositivity in a health care worker population during the early pandemic.
  Schubl, S., Figueroa, C., Palma, A., de Assis, R., Jain, A., Nakajima, R., Jasinskas, A., Brabender, D., Hosseinian, S., Naaseh, A., Hernandez Dominguez, O., Runge, A....> ;BMC Infectious Diseases. 2023 May 16
• 7 citations
  Preneoplastic stromal cells promote BRCA1-mediated breast tumorigenesis.
  Kevin Nee, Dennis Ma, Quy H Nguyen, Maren Pein, Nicholas Pervolarakis, Jacob Insua-Rodríguez, Yanwen Gong, Grace Hernandez, Hamad Alshetaiwi, Justice Williams, Maha Ra...> ;Nature Genetics. 2023 Apr 1
• Beyond Costs: Pragmatic Considerations for Pooling of SARS-CoV-2 Test Samples for Nursing Home Surveillance.
  Gabrielle M Gussin, Raveena D Singh, Delia F Tifrea, Thomas Tjoa, Cassiana E Bittencourt, Robert A Edwards, Edwin S Monuki, Susan S Huang> ;Microbiology Spectrum. 2023 Feb 1
• 4 citations
  A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease.
  Stephanie J Hachey, Agua Sobrino, John G Lee, Mehraneh D Jafari, Samuel J Klempner, Eric J Puttock, Robert A Edwards, John S Lowengrub, Marian L Waterman, Jason A Zell...> ;Translational Research. 2023 May 1
• Hypertrophic and fibrotic human PKD hearts are associated with macrophage infiltration and abnormal TGF-βsignaling.
  Farideh Amirrad, Gregory A Fishbein, Robert A Edwards, Surya M Nauli> ;Cell and Tissue Research. 2023 Jan 1
• Selective Neural Electrical Stimulation of an Injured Facial Nerve Using Chronically Implanted Dual Cuff Electrodes.
  Arash Abiri, Steven Chau, Nathan R James, Jack L Birkenbeuel, Ronald Sahyouni, Robert Edwards, Hamid R Djalilian, Harrison W Lin, Goshtasbi, K.> ;Brain Sciences. 2022 Oct 27
• 24 citations
  Disruption of the circadian clock drivesloss of heterozygosity to accelerate colorectal cancer.
  Sung Kook Chun, Bridget M Fortin, Rachel C Fellows, Amber N Habowski, Amandine Verlande, Wei A Song, Alisa L Mahieu, Austin E Y T Lefebvre, Jason N Sterrenberg, Leandr...> ;Science Advances. 2022 Aug 12
• 12 citations
  Discovery of compounds that reactivate p53 mutants in vitro and in vivo.
  Geetha Durairaj, Özlem Demir, Bryant Lim, Roberta Baronio, Delia Tifrea, Linda V Hall, Jacob C DeForest, Linda Lauinger, Maryam M Jebril Fallatah, Clinton Yu, Hosung B...> ;Cell Chemical Biology. 2022 Sep 15
• 13 citations
  Single-cell RNA sequencing reveals immunological rewiring at the maternal-fetal interface following asymptomatic/mild SARS-CoV-2 infection.
  Suhas Sureshchandra, Michael Z Zulu, Brianna M Doratt, Allen Jankeel, Delia Tifrea, Robert Edwards, Monica Rincon, Nicole E Marshall, Ilhem Messaoudi> ;Cell Reports. 2022 Jun 14
• 5 citations
  Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.
  Sohail Jahid, Jose A Ortega, Linh M Vuong, Isabella Maria Acquistapace, Stephanie J Hachey, Jessica L Flesher, Maria Antonietta La Serra, Nicoletta Brindani, Giuseppin...> ;Cell Reports. 2022 Apr 5
• 10 citations
  Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice.
  Gema M Olivarria, Yuting Cheng, Susana Furman, Collin Pachow, Lindsay A Hohsfield, Charlene Smith-Geater, Ricardo Miramontes, Jie Wu, Mara S Burns, Kate I Tsourmas, Je...> ;Journal of Virology. 2022 Feb 23
• No difference in factual or conceptual recall comprehension for tablet, laptop, and handwritten note-taking by medical students in the United States: a survey-based ob...
  Warren Wiechmann, Robert Edwards, Cheyenne Low, Alisa Wray, Megan Boysen-Osborn, Shannon Toohey> ;Journal of Educational Evaluation for Health Professions. 2022 Jan 1
• 6 citations
  Infection prevention strategies are highly protective in COVID-19 units while main risks to healthcare professionals come from coworkers and the community.
  Shruti K. Gohil, Kathleen A. Quan, Keith M Madey, Suzanne King-Adelsohn, Tom Tjoa, Delia F. Tifrea, Bridgit Crews, Edwin S. Monuki, Saahir Khan, Sebastian D. Schubl, C...> ;Antimicrobial Resistance and Infection Control. 2021 Nov 22
• 5 citations
  Disruption of beta-catenin dependent Wnt signaling in colon cancer cells remodels the microenvironment to promote tumor invasion.
  George Chen, Delia F. Tifrea, Rabi Murad, Amber N Habowski, Yung Lyou, Madeleine R. Duong, Linzi Hosohama, Ali Mortazavi, Robert Edwards, Marian L. Waterman> ;Molecular Cancer Research. 2021 Nov 19
• 4 citations
  Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice
  Gema M Olivarria, Yuting Cheng, Collin Pachow, Lindsay A. Hohsfield, Charlene Smith-Geater, Ricardo Miramontes, Jie Wu, Mara S Burns, Kate I. Tsourmas, Jennifer Stocks...> ;Biorxiv. 2021 Nov 17
• 20 citations
  Perspective on taxonomic classification of uncultivated viruses.
  Bas E. Dutilh, Arvind Varsani, Yigang Tong, Peter Simmonds, Sead Sabanadzovic, Luisa Rubino, Simon Roux, Alejandro Reyes Muñoz, Cédric Lood, Elliot J. Lefkowitz, Jens ...> ;Current Opinion in Virology. 2021 Nov 12
• 4 citations
  Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis.
  Dennis Ma, Grace A. Hernandez, Austin E. Y. T. Lefebvre, Hamad Alshetaiwi, Kerrigan Blake, Kushal R. Dave, Maha Rauf, Justice W. Williams, Ryan T. Davis, Katrina Evans...> ;Communications Biology. 2021 Nov 5
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