RobertAikenMD

Neurooncology

Director, Neuro-oncology Program, Co-director, Gerald J. Glasser Brain Tumor Center, Atlantic Healthcare, Summit and Morristown, NJ

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Office
99 Beauvoir Avenue
Fifth Floor
Summit, NJ 07901
Phone+1 908-522-5914

Fax+1 908-522-5845
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Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Neuro-Oncology, 1981 - 1983
New York Presbyterian Hospital (Columbia Campus)Residency, Neurology, 1978 - 1981
Baylor College of MedicineResidency, Internal Medicine, 1976 - 1978
Wayne State University School of MedicineClass of 1976

Certifications & Licensure

NY State Medical License 1979 - 2025
NJ State Medical License 2017 - 2025
IL State Medical License 2017 - 2021
PA State Medical License 1982 - 2012
MI State Medical License 1978 - 2006
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

America's Top Doctors for Cancer Castle Connolly, 2014-2023
America's Top Doctors 2014-2023
Marquis Who's Who in America 2011-2023
Chicago Magazine: Top Doctors Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013
Top Doctors: New York Metro Area Castle Connolly, 2009-2010
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Clinical Trials

Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas Start of enrollment: 2012 Dec 01
Terminated
Phase 1, Phase 2

Publications & Presentations

PubMed

10 citations
Leptomeningeal Disease in Glioblastoma: Endgame or Opportunity?
Elizabeth E. Ginalis, Nitesh V Patel, Robert Aiken, Alis J. Dicpinigaitis, Simon Hanft, Ginalis, E., Sarfraz Akmal> ;Journal of Neuro-Oncology. 2021 Oct 8
7 citations
Generation of glioblastoma patient-derived organoids and mouse brain orthotopic xenografts for drug screening
Christian Moya Gamboa, Kelly Jara, Sahithi Pamarthy, Liqiong Liu, Robert Aiken, Zhenggang Xiong, Shabbar F. Danish, Hatem E. Sabaawy> ;STAR Protocols. 2021 Feb 18
7 citations
BRAINSTORM: A Multi-Institutional Phase 1/2 Study of RRx-001 in Combination With Whole Brain Radiation Therapy for Patients With Brain Metastases.
Michelle M. Kim, Hemant Parmar, Matthew J. Schipper, Theresa Devasia, Madhava P. Aryal, Santosh Kesari, Steven J. O'Day, Aki Morikawa, Daniel E. Spratt, Larry Junck, A...> ;International Journal of Radiation Oncology, Biology, Physics. 2020 Jul 1
135 citations
A Randomized Double-Blind Placebo-Controlled Phase II Trial of Dendritic Cell Vaccine ICT-107 in Newly Diagnosed Patients with Glioblastoma.
Patrick Y. Wen, David A. Reardon, Terri S. Armstrong, Surasak Phuphanich, Robert Aiken, Joseph Landolfi, William T. Curry, Jay-Jiguang Zhu, Michael Glantz, David M. Pe...> ;Clinical Cancer Research. 2019 Oct 1
42 citations
Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration.
Mark N. Stein, Jyoti Malhotra, Rohinton Tarapore, Usha Malhotra, Ann W. Silk, Nancy Chan, Lorna Rodriguez, Joseph Aisner, Robert Aiken, Tina M. Mayer, Bruce G. Haffty,...> ;Journal for Immunotherapy of Cancer. 2019 May 22
9 citations
Correction: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma [J Transl Med., 16, (...
Linda M. Liau, Keyoumars Ashkan, David Tran, Jian Campian, John E. Trusheim, Charles S. Cobbs, Jason Heth, Michael Salacz, Sarah A. Taylor, Stacy D. D’Andre, Fabio M. ...> ;Journal of Translational Medicine. 2018 Jun 29
167 citations
First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.
Linda M Liau, Keyoumars Ashkan, David D Tran, Jian L Campian, John E Trusheim, Charles S Cobbs, Jason A Heth, Michael Salacz, Sarah Taylor, Stacy D D'Andre, Fabio M Iw...> ;Journal of Translational Medicine. 2018 May 29
24 citations
Phase I clinical trial of AXL1717 for treatment of relapsed malignant astrocytomas: analysis of dose and response
Robert Aiken, Magnus Axelson, Johan Harmenberg, Maria Klockare, Olle Larsson, Cecilia Wassberg> ;Oncotarget. 2017 Sep 6
A 54-Year-Old Male with Multiple Intracranial and Extracranial Masses.
Diana Murro Lin, Aidnag Z. Diaz, Robert Aiken, Paolo Gattuso, Sukriti Nag> ;Brain Pathology. 2017 Sep 1
100 citations
First-in-Human Clinical Trial of Oral ONC201 in Patients with Refractory Solid Tumors
Mark N. Stein, Joseph R. Bertino, Howard L. Kaufman, Tina M. Mayer, Rebecca A. Moss, Ann W. Silk, Nancy Chan, Jyoti Malhotra, Loma Rodriguez, Joseph Aisner, Robert Aik...> ;Clinical Cancer Research. 2017 Aug 1
Primary brain tumors: introduction.
Robert Aiken, Richard W. Byrne> ;Seminars in Oncology. 2014 Aug 1
9 citations
Molecular neuro-oncology and the challenge of the blood-brain barrier.
Robert Aiken> ;Seminars in Oncology. 2014 Aug 1
25 citations
Phase I trial of verubulin (MPC-6827) plus carboplatin in patients with relapsed glioblastoma multiforme
Kenneth F. Grossmann, Howard Colman, Wallace A. Akerley, Michael Glantz, Yuko Matsuoko, Andrew P. Beelen, Margaret K. Yu, John de Groot, Robert Aiken, Jeffery J. Olsen...> ;Journal of Neuro-Oncology. 2012 Aug 30
Neurologic complications of head and neck cancers.
Robert D. Aiken> ;Seminars in Oncology. 2006 Jun 1
88 citations
An open label trial of sustained-release cytarabine (DepoCyt) for the intrathecal treatment of solid tumor neoplastic meningitis.
Kurt A. Jaeckle, Tracy T. Batchelor, Steven J. O'Day, Surasak Phuphanich, Pamela New, Glenn J. Lesser, Allen Cohn, Mark R. Gilbert, Robert Aiken, Deborah Heros, Lisa R...> ;Journal of Neuro-Oncology. 2002 Jan 1
153 citations
Results of a Pilot Study Involving the Use of an Antisense Oligodeoxynucleotide Directed Against the Insulin-Like Growth Factor Type I Receptor in Malignant Astrocytomas
David W. Andrews, Mariana Resnicoff, Adam E. Flanders, Lawrence C. Kenyon, Mark T. Curtis, Gino Merli, Renato Baserga, George Iliakis, Robert D. Aiken> ;Journal of Clinical Oncology. 2001 Apr 15
76 citations
Intrathecal treatment of neoplastic meningitis due to breast cancer with a slow-release formulation of cytarabine
Kurt A. Jaeckle, Surasak Phuphanich, M. J. van den Bent, Robert Aiken, Tracy T. Batchelor, Thomas B. Campbell, Dorcas Fulton, Mark R. Gilbert, Deborah Heros, Lisa R. R...> ;British Journal of Cancer. 2001 Feb 13
42 citations
Regression of C6 rat brain tumors by cells expressing an antisense insulin-like growth factor I receptor RNA
Mariana Resnicoff, Juri Gelovani Tjuvajev, Harris L. Rotman, David Abraham, Mark T. Curtis, Robert Aiken, Renato Baserga> ;Journal of Experimental Therapeutics & Oncology. 1996 Nov 1
30 citations
QUALITY-OF-LIFE ISSUES IN PATIENTS WITH MALIGNANT GLIOMAS
R D Aiken> ;Seminars in Oncology. 1994 Jan 1
6 citations
Metronidazole in the treatment of metastatic brain tumors. Results of a controlled clinical trial.
Robert Aiken, John M Leavengood, Jae Ho Kim, Michael D. F. Deck, Howard T. Thaler, Jerome B. Posner> ;Journal of Neuro-Oncology. 1984 Jan 1
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Press Mentions

Overlook Medical Center Chosen as SURVIVE Trial Site, Enrolling Patients for New Brain Tumor VaccineFebruary 22nd, 2022
Rutgers Cancer Institute of New Jersey Doctors Named Among ‘Tops’ in Oncology CareJuly 23rd, 2019
Overlook Medical Center Chosen as Trial Site for Brain Tumor TreatmentJune 27th, 2023
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