RobertCharlesBucelliMDPhD

Neurology • Saint Louis, MO

Neuromuscular Medicine

Associate Professor, Neurology, Washington University in St. Louis School of Medicine

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Office
4921 Parkview Pl
Saint Louis, MO 63110
Phone+1 314-362-7241

Fax+1 314-362-0338
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Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Neuromuscular Medicine (Neurology), 2011 - 2012
Washington University/B-JH/SLCH ConsortiumResidency, Neurology, 2007 - 2011
Jacobs School of Medicine and Biomedical Sciences at the University at BuffaloClass of 2007
Canisius CollegeB.S., Biology, Summa Cum Laude, 2001

Certifications & Licensure

IL State Medical License 2021 - 2026
MO State Medical License 2011 - 2025
American Board of Psychiatry and Neurology Neurology
American Board of Psychiatry and Neurology Neuromuscular Medicine

Awards, Honors, & Recognition

Certified Clinical Neuromuscular Pathology United Council for Neurologic Subspecialties (UCNS), 2015
Eliasson Award for Teaching Excellence Department of Neurology, Washington University, 2013-2015
Medical Student Teaching Award Department of Neurology, Washington University, 2013, 2015
Distinguished Service Teaching Awards, Clinical Teacher of the Year Award Washington University, 2014
Medical Student Teaching Honor Roll Department of Neurology, Washington University, 2014
CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012
Certified Neurology ABPN, 2011
Administrative Chief Fellow Neuromuscular Division, Washington University, 2011
Co-recipient, The Leonard Berg Award for Resident Research Department of Neurology, Washington University, 2010
Herbert Schuel Research in Cell/Developmental Biology Award 2007
Alpha Omega Alpha National Honor Society 2007
Dean’s Letter of Commendation State University of New York at Buffalo, 2002-2003, 2006-2007
Excellence in Neuroscience Research Award Canisius College, 2001
Deans’ Honor List Canisius College, 1997-2001
Alpha Sigma Nu 2000
Research Award Recipient Howard Hughes Medical Institute, 2000
Excellence Program Research Award Canisius College, 1998-1999
All College Honors Program Canisius College, 1997
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Publications & Presentations

PubMed

Lumbar punctures are safe in patients with ALS and have a risk profile similar to that in the non-ALS population.
Collin J Kreple, Saivaroon Gajagowni, Jennifer Jockel-Balsaratti, Robert C Bucelli, Timothy M Miller> ;Muscle & Nerve. 2023 Nov 1
1 citations
Protein kinetics of superoxide dismutase-1 in familial and sporadic amyotrophic lateral sclerosis.
Cindy V Ly, Margaret D Ireland, Wade K Self, James Bollinger, Jennifer Jockel-Balsarotti, Hillary Herzog, Peggy Allred, Leah Miller, Michael Doyle, Isabel Anez-Bruzual...> ;Annals of Clinical and Translational Neurology. 2023 Jun 1
1 citations
Real-time quaking-induced conversion assays for prions: Applying a sensitive but imperfect test in clinical practice.
Samuel M Jones, Evelyn B Lazar, Amanda L Porter, Christian C Prusinski, Matthew R Brier, Robert C Bucelli, Gregory S Day> ;European Journal of Neurology. 2023 Jul 1
Schwann cells and myelin in human peripheral nerve: Major protein components vary with age, axon size and pathology.
Alan Pestronk, Robert E Schmidt, Robert Bucelli, Julia Sim> ;Neuropathology and Applied Neurobiology. 2023 Apr 1
Location-atypical lesions in non-ketotic hyperglycemic epilepsy: expanding the clinico-radiographic phenotype
Jordan Y. Amar, Anup K. Bhattacharya, Adaku M. Uzo-Okereke, Chris A. Chou, Katie D. Vo, Manu S. Goyal, Robert C. Bucelli> ;Epileptic Disorders. 2022 Dec 1
4 citations
Whole-Genome and Long-Read Sequencing Identify a Novel Mechanism inResulting in CANVAS Syndrome.
Katherine Abell King, Daniel J Wegner, Robert C Bucelli, Jessica Shapiro, Alexander J Paul, Patricia I Dickson, Jennifer A Wambach> ;Neurology. Genetics. 2022 Dec 1
3 citations
Correction to: Design of a Randomized, Placebo-Controlled, Phase 3 Trial of Tofersen Initiated in Clinically Presymptomatic SOD1 Variant Carriers: the ATLAS Study.
Michael Benatar, Joanne Wuu, Peter M Andersen, Robert C Bucelli, Jinsy A Andrews, Markus Otto, Nita A Farahany, Elizabeth A Harrington, Weiping Chen, Adele A Mitchell,...> ;Neurotherapeutics. 2022 Sep 1
10 citations
Septin-5 and -7-IgGs: Neurologic, Serologic, and Pathophysiologic Characteristics.
Shannon R Hinson, Josephe A Honorat, Ethan M Grund, Benjamin D Clarkson, Ramona Miske, Madeleine Scharf, Cecilia Zivelonghi, Muhammad Taher Al-Lozi, Robert C Bucelli, ...> ;Annals of Neurology. 2022 Dec 1
4 citations
Interpreting Electrodiagnostic Studies for the Management of Nerve Injury.
Stahs Pripotnev, Robert C Bucelli, J Megan M Patterson, Andrew Yee, Mitchell A Pet, Susan Mackinnon> ;The Journal of Hand Surgery. 2022 Sep 1
3 citations
Incidence of amyotrophic lateral sclerosis in older adults.
Alejandra Camacho-Soto, Susan Searles Nielsen, Irene M Faust, Robert C Bucelli, Timothy M Miller, Brad A Racette> ;Muscle & Nerve. 2022 Sep 1
42 citations
Design of a Randomized, Placebo-Controlled, Phase 3 Trial of Tofersen Initiated in Clinically Presymptomatic SOD1 Variant Carriers: the ATLAS Study.
Michael Benatar, Joanne Wuu, Peter M Andersen, Robert C Bucelli, Jinsy A Andrews, Markus Otto, Nita A Farahany, Elizabeth A Harrington, Weiping Chen, Adele A Mitchell,...> ;Neurotherapeutics. 2022 Jul 1
3 citations
Prevalence of Surgical Procedures at Symptomatic Onset of Prion Disease.
Amanda L Porter, Christian C Prusinski, Evelyn Lazar, Clara Yuh, Robert C Bucelli, Brian S Appleby, Gregory S Day> ;JAMA Network Open. 2022 Mar 1
1 citations
Introduction. Awake spinal surgery: where are we now and where are we going.
Wilson Z. Ray, Asdrubal Falavigna, Praveen V. Mummaneni, Robert C. Bucelli> ;Neurosurgical Focus. 2021 Dec 1
22 citations
A phase Ib/IIa clinical trial of dantrolene sodium in patients with Wolfram syndrome
Damien Abreu, Stephen I. Stone, Toni S. Pearson, Robert C. Bucelli, Ashley N Simpson, Stacy Hurst, Cris M. Brown, Kelly Kries, Chinyere Onwumere, Hongjie Gu, James Hoe...> ;JCI Insight. 2021 Aug 9
Reducing body myopathy associated with the LIM2 p.(His123Arg) FHL1 variant.
Leila Darki, Arash Jalali-Sohi, Samuel Guzman, Anna Mathew, Robert C. Bucelli, Kyle Hurth, Said R. Beydoun> ;Clinical Neurology and Neurosurgery. 2021 Aug 1
3 citations
Biallelic ASCC1 variants including a novel intronic variant result in expanded phenotypic spectrum of spinal muscular atrophy with congenital bone fractures 2 (SMABF2).
Kristen K Rosano, Daniel J. Wegner, Marwan Shinawi, Dustin Baldridge, Robert C. Bucelli, Sonika Dahiya, Frances V. White, Marcia C. Willing, William McAllister, Ryan J...> ;American Journal of Medical Genetics. Part A. 2021 May 1
10 citations
Clinical utility of anti-cytosolic 5'-nucleotidase 1A antibody in idiopathic inflammatory myopathies.
Chiseko Ikenaga, Andrew R. Findlay, Namita Goyal, Sarah Robinson, Jonathan Cauchi, Yessar Hussain, Leo H. Wang, Joshua C. Kershen, Brent A. Beson, Michael Wallendorf, ...> ;Annals of Clinical and Translational Neurology. 2021 Feb 8
5 citations
Flortaucipir (tau) PET in LGI1 antibody encephalitis.
Gregory S. Day, Brian A. Gordon, Austin A. McCullough, Robert C. Bucelli, Richard J. Perrin, Tammie L.S. Benzinger, Beau M. Ances> ;Annals of Clinical and Translational Neurology. 2021 Jan 7
2 citations
Leveraging molecular biomarkers to make the common diagnosis in the uncommon patient
Gregory S. Day, Brian A. Gordon, Robert C. Bucelli, Richard J. Perrin, A. Sebastian Lopez-Chiriboga, Beau M. Ances> ;Journal of Neuroimmunology. 2021 Mar 15
257 citations
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The New England Journal of Medicine. 2020 Jul 8
41 citations
Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms
Hyunglok Chung, Michael F. Wangler, Paul C. Marcogliese, Juyeon Jo, Thomas A. Ravenscroft, Zhongyuan Zuo, Lita Duraine, Sina Sadeghzadeh, David Li-Kroeger, Robert E. S...> ;Neuron. 2020 May 20
50 citations
Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation.
Ekaterina Esaulova, Claudia Cantoni, Irina Shchukina, Konstantin Zaitsev, Robert C. Bucelli, Gregory F. Wu, Maxim N. Artyomov, Anne H. Cross, Brian T. Edelson> ;Neurology(R) Neuroimmunology & Neuroinflammation. 2020 Jul 1
3 citations
An Atypical and Multifactorial Acute Immune Polyradiculopathy: A Case Report.
Matthew R. Brier, Elyse A. Everett, Robert C. Bucelli> ;The Neurohospitalist. 2020 Apr 1
2 citations
An Elderly Man with Dementia
Matthew R. Brier, Robert C. Bucelli, Gregory S. Day> ;Clinical Chemistry. 2020 Mar 1
8 citations
Testing for N-methyl-d-aspartate Receptor Autoantibodies in Clinical Practice.
John Brooks, Melanie L. Yarbrough, Robert C. Bucelli, Gregory S. Day> ;The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 2020 Jan 1
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Journal Articles

CANOMAD and Other Chronic Ataxic Neuropathies with Disialosyl Antibodies (CANDA)
R Brian Sommerville, Craig M Zaidman, Glenn Lopate, Alan Pestronk, Conrad C Weihl, Robert C Bucelli, Journal of Neurology
A young woman with blurred vision and distal paresthesias
Kung NH, Bartlett NL, Yaseen NR, Van Stavern GP, Bucelli RC, JAMA Neurology, 1/26/2015
Neurologic manifestations of intravascular large B-cell lymphoma
Tahsili-Fahadan P, Rashidi A, Cimino PJ, Bucelli RC, Keyrouz SG, Neurology Clinical Practice, 1/19/2015
Neuro-Sweet disease: A case of recurrent encephalitis and febrile neutrophilic dermatosis
Yuan K, Musiek AC, Schaffer A, Bucelli RC, Neurology Clinical Practice, 1/10/2015
Neuromuscular emergencies
Bucelli RC, Harms MB, Semin Neurol, 1/1/2015
Peripheral nervous system hyperexcitability in VV2 sporadic Creutzfeldt-Jakob disease
Ong CJ, Al-Lozi M, Cimino PJ, Bucelli RC, Neurology: Clinical Practice, 1/1/2015
Ocular neuromyotonia associated with chronic inflammatory demyelinating polyneuropathy
Kung NH, Bucelli RC, McClelland CM, Van Stavern GP, Neuro-Ophthalmology, 1/1/2015
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Press Mentions

Hints That Experimental Drug Might Curb a Form of ALSSeptember 23rd, 2022
Longer-Term Use of Investigational Drug Stabilizes ALS SymptomsSeptember 22nd, 2022
Investigational Drug for Genetic Form of ALS Improves Disease’s Molecular SignsSeptember 21st, 2022
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