RobertLCarithersJrMD

Gastroenterology • Seattle, WA

Hepatology & Liver Transplantation

Professor, Medicine, University of Washington School of Medicine

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Office
1959 Ne Pacific St
# 356174
Seattle, WA 98195
Phone+1 206-598-4908
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Education & Training

University of North Carolina HospitalsResidency, Internal Medicine, 1969 - 1973
Perelman School of Medicine at the University of PennsylvaniaClass of 1969

Certifications & Licensure

WA State Medical License 1990 - 2025
American Board of Internal Medicine Internal Medicine

Clinical Trials

Hepatitis B Research Network Adult Cohort Study Start of enrollment: 2010 Dec 01
Completed
HBRN: Immune Regulation and Costimulation in Natural History of Chronic Hepatitis B Start of enrollment: 2011 Feb 01
Active, not recruiting

Publications & Presentations

PubMed

Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual...
Louvet, A.,Thursz, M. R.,Kim, D. J.,Labreuche, J.,Atkinson, S. R.,Sidhu, S. S.,O'Grady, J. G.,Akriviadis, E.,Sinakos, E.,Carithers, R. L.,Ramond, M. J.,Maddrey, W. C.,...> ;Gastroenterology. 2018 May 09
Recent trends in liver transplantation for alcoholic liver disease in the United States.
Kling, C. E.,Perkins, J. D.,Carithers, R. L.,Donovan, D. M.,Sibulesky, L.> ;World J Hepatol. 2018 Jan 24
Hepatitis B Virus-Specific and Global T-Cell Dysfunction in Chronic Hepatitis B.
Park, J. J.,Wong, D. K.,Wahed, A. S.,Lee, W. M.,Feld, J. J.,Terrault, N.,Khalili, M.,Sterling, R. K.,Kowdley, K. V.,Bzowej, N.,Lau, D. T.,Kim, W. R.,Smith, C.,Carither...> ;Gastroenterology. 2015 Dec 20
Congestive hepatic fibrosis score: a novel histologic assessment of clinical severity.
Dai, D. F.,Swanson, P. E.,Krieger, E. V.,Liou, I. W.,Carithers, R. L.,Yeh, M. M.> ;Mod. Pathol.. 2014 Jun 14
Advancing the high throughput identification of liver fibrosis protein signatures using multiplexed ion mobility spectrometry.
Baker, E. S.,Burnum-Johnson, K. E.,Jacobs, J. M.,Diamond, D. L.,Brown, R. N.,Ibrahim, Y. M.,Orton, D. J.,Piehowski, P. D.,Purdy, D. E.,Moore, R. J.,Danielson, W. F.,Mo...> ;Mol. Cell Proteomics. 2014 Jan 10
The HALOS-ND model: a step in the journey of predicting hospital length of stay after liver transplantation.
Krishnan, K. R.,Bhattacharya, R.,Pereira, A.,Otto, A. K.,Carithers, R. L.,Reyes, J. D.,Perkins, J. D.> ;Clin Transplant. 2013 Sep 2
Proteome and computational analyses reveal new insights into the mechanisms of hepatitis C virus mediated liver disease post-transplantation.
Diamond, D.L., Krasnoselsky, A.L., Burnum, K.E., Monroe, M.E., Webb-Robertson, B., McDermott, J.E., Yeh, M.M., Golib Dzib, J.F., Susnow, N., Strom, S., Proll, S.C., Be...> ;Hepatology. 2012 Jul
Early transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients.
Rasmussen, A.L., Tchitchek, N., Susnow, N.J., Krasnoselsky, A.L., Diamond, D.L., Yeh, M.M., Proll, S.C., Korth, M.J., Walters, K., Lederer, S., Larson, A.M., Carithers...> ;Hepatology. 2012 Jul
Genetic diversity of hepatitis C virus predicts recurrent disease after liver transplantation.
Li, H., Sullivan, D.G., Feuerborn, N., McArdle, S., Bekele, K., Pal, S., Yeh, M., Carithers, R.L., Perkins, J.D., Gretch, D.R.> ;Virology. 2010 Jul 5
Use of an automated clinical management system improves outpatient immunosuppressive care following liver transplantation.
Park, E.S., Peccoud, M.R., Wicks, K.A., Halldorson, J.B., Carithers, R.L., Reyes, J.D., Perkins, J.D.> ;J Am Med Inform Assoc. 2010-07-01
Liver transplantation at the extremes of the body mass index.
Dick, A.S., Spitzer, A.L., Seifert, C.F., Deckert, A., Carithers, R.L., Reyes, J.D., Perkins, J.D.> ;Liver Transpl. 2009-08-01
17 citations
Should liver transplantation in patients with model for end-stage liver disease scores ≤ 14 be avoided? A decision analysis approach†
James D. Perkins, Jeffrey B. Halldorson, Ramasamy Bakthavatsalam, Oren K. Fix, Robert L. Carithers, Jorge D. Reyes> ;Liver Transplantation. 2009 Feb 1
Investigation of putative multisubtype hepatitis C virus infections in vivo by heteroduplex mobility analysis of core/envelope subgenomes.
Li, H., Thomassen, L.V., Majid, A., McMahon, B.J., Bruden, D., McArdle, S., Bano, N., Chung, M., Carithers, R.L., Perkins, J.D., Sullivan, D.G., Gretch, D.R.> ;J Virol. 2008 Aug
Liver transplantation for hepatocellular carcinoma: impact of the MELD allocation system and predictors of survival.
Ioannou, G.N., Perkins, J.D., Carithers, R.L.> ;Gastroenterology. 2008 May
Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction.
Diamond, D.L., Jacobs, J.M., Paeper, B., Proll, S.C., Gritsenko, M.A., Carithers, R.L., Larson, A.M., Yeh, M.M., Camp, D.G., Smith, R.D., Katze, M.G.> ;Hepatology. 2007 Sep
Recipient and donor factors influence the incidence of graft-vs.-host disease in liver transplant patients.
Chan, E.Y., Larson, A.M., Gernsheimer, T.B., Kowdley, K.V., Carithers, R.L., Reyes, J.D., Perkins, J.D.> ;Liver Transpl. 2007 Apr
Identification of a specific gene expression pattern associated with HCV-induced pathogenesis in HCV- and HCV/HIV-infected individuals.
Walters, K., Smith, M.W., Pal, S., Thompson, J.C., Thomas, M.J., Yeh, M.M., Thomas, D.L., Fitzgibbon, M., Proll, S., Fausto, N., Gretch, D.R., Carithers, R.L., Shuhart...> ;Virology. 2006 Jul 5
Productive replication of hepatitis C virus in perihepatic lymph nodes in vivo: implications of HCV lymphotropism.
Pal, S., Sullivan, D.G., Kim, S., Lai, K.K., Kae, J., Cotler, S.J., Carithers, R.L., Wood, B.L., Perkins, J.D., Gretch, D.R.> ;Gastroenterology. 2006 Apr
Gene expression patterns that correlate with hepatitis C and early progression to fibrosis in liver transplant recipients.
Smith, M.W., Walters, K., Korth, M.J., Fitzgibbon, M., Proll, S., Thompson, J.C., Yeh, M.M., Shuhart, M.C., Furlong, J.C., Cox, P.P., Thomas, D.L., Phillips, J.D., Kus...> ;Gastroenterology. 2006 Jan
Liver transplantation for erythropoietic protoporphyria liver disease.
McGuire, B.M., Bonkovsky, H.L., Carithers, R.L., Chung, R.T., Goldstein, L.I., Lake, J.R., Lok, A.S., Potter, C.J., Rand, E., Voigt, M.D., Davis, P.R., Bloomer, J.R.> ;Liver Transpl. 2005 Dec
Using root cause analysis to improve survival in a liver transplant program.
Perkins, J.D., Levy, A.E., Duncan, J.B., Carithers, R.L.> ;J Surg Res. 2005 Nov
Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis.
Combes, B., Emerson, S.S., Flye, N.L., Munoz, S.J., Luketic, V.A., Mayo, M.J., McCashland, T.M., Zetterman, R.K., Peters, M.G., Di Bisceglie, A.M., Benner, K.G., Kowdl...> ;Hepatology. 2005 Nov
Proteome analysis of liver cells expressing a full-length hepatitis C virus (HCV) replicon and biopsy specimens of posttransplantation liver from HCV-infected patients.
Jacobs, J. M.,Diamond, D. L.,Chan, E. Y.,Gritsenko, M. A.,Qian, W.,Stastna, M.,Baas, T.,Camp, D. G.,Carithers, R. L.,Smith, R. D.,Katze, M. G.> ;J Virol. 2005 Jun
Is central obesity associated with cirrhosis-related death or hospitalization? A population-based, cohort study.
Ioannou, G.N., Weiss, N.S., Boyko, E.J., Kowdley, K.V., Kahn, S.E., Carithers, R.L., Tsai, E.C., Dominitz, J.A.> ;Clin Gastroenterol Hepatol. 2005 Jan
Prolonged follow-up of patients in the U.S. multicenter trial of ursodeoxycholic acid for primary biliary cirrhosis.
Combes, B., Luketic, V.A., Peters, M.G., Zetterman, R.K., Garcia-Tsao, G., Munoz, S.J., Lin, D., Flye, N., Carithers, R.L.> ;Am J Gastroenterol. 2004 Feb
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Grant Support

Hepatitis Beta Research Network Clinical Center In Pacific Northwest/AlaskaNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2011
Hepatities Beta Research Network Clinical Center In Pacific Northwest/AlaskaNational Institute Of Diabetes And Digestive And Kidney Diseases2008
Studies Of The Natural History Of Hepatitis C In LiverNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2002
Ursodeoxycholate(Udca) VS UDCA And MethotrexateNational Center For Research Resources2000
PEG IFN Vs. Intron A For Chronic Hepatitis CNational Center For Research Resources1998–2000
Intron A And 2 Doses Of RibavirinNational Center For Research Resources1998–2000
Adefovir For Hepatitis BNational Center For Research Resources1998–2000
Intron A VS Intron A + Ribavirin For Treatment Of Relapse In PatientsNational Center For Research Resources1997–2000
Intron A VS Intron A + Ribavirin For Hepatitis C In Interferon Naive PatientsNational Center For Research Resources1997–2000
Continuous VS 24 Wk Courses Of Intron A Therapy For Hepatitis C Virus InfectionNational Center For Research Resources1997–2000
Trial Of Ursodeoxycholate For Primary Biliary CirrhosisNational Center For Research Resources1996–2000
Interferon Therapy In Chronic Hepatitis CNational Center For Research Resources1996–2000
Screening Protocol For The Treatment Of Hepatitis CNational Center For Research Resources1998–1999
Betaseron For Hepatitis CNational Center For Research Resources1996–1999
Pharmacology Of Optimark In Patients With Central Nervous System Or Liver DISNational Center For Research Resources1997
Treatment Of Patients With Chronic Hepatitis C To Evaluate R-842National Center For Research Resources1996–1997
P450 Induction In Tuberculosis PatientsNational Center For Research Resources1996
Continuous VS 24 Week Courses Of Intron A Therapy For Hepatitis CNational Center For Research Resources1996
Ursodeoxycholic Acid Treatment Of Primary Biliary CirrhosisNational Center For Research Resources1992–1993
Liver Biopsy ONE Year Following Distal Gastric BypassNational Center For Research Resources1992
Liver TransplantationNational Center For Research Resources1985–1992
Urodeoxycholic Acid Treatment Of Primary Biliary CirrhosisNational Center For Research Resources1990
Non-A, Non-B HepatitisNational Center For Research Resources1987–1990
Plasmapheresis Of Hepatitis B Surface Antigens CarriersNational Center For Research Resources1985–1987
Severe Hepatitis ProtocolNational Center For Research Resources1985–1986
Serologic Studies In Non-A, Non-B HepatitisNational Center For Research Resources1985–1986
Prednisolone Versus Placebo Therapy In Alcoholic HepatitisNational Center For Research Resources1985–1986
Chronic Active Hepatitis ProtocolNational Center For Research Resources1985–1986
Acute Viral And Drug-Induced Hepatitis--Effect Of PrednisoloneNational Center For Research Resources1985–1986

Hospital Affiliations

UW Medicine/University of Washington Medical CenterSeattle, Washington