RobertCoffeyMD

PubMed

• Investigation of Novel Urinary Biomarkers in Hepatocellular Carcinoma Risk in a Predominantly African American Population: A Case-Control Study.
  Xijing Han, Lei Fan, Ginger L Milne, Qi Dai, Martha Shrubsole, Alexandra Shingina, Harvey Murff, Robert Coffey> ;Gastrointestinal Tumors. 2024 Mar 8
• 7 citations
  Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors.
  Cody N Heiser, Alan J Simmons, Frank Revetta, Eliot T McKinley, Marisol A Ramirez-Solano, Jiawei Wang, Harsimran Kaur, Justin Shao, Gregory D Ayers, Yu Wang, Sarah E G...> ;Cell. 2023 Dec 7
• Development of Pluoronic nanoparticles of fluorocoxib A for endoscopic fluorescence imaging of colonic adenomas.
  Md Jashim Uddin, Hiroaki Niitsu, Robert J Coffey, Lawrence J Marnett> ;Journal of Biomedical Optics. 2023 Apr 1
• 22 citations
  Comprehensive isolation of extracellular vesicles and nanoparticles.
  Qin Zhang, Dennis K Jeppesen, James N Higginbotham, Jeffrey L Franklin, Robert J Coffey> ;Nature Protocols. 2023 May 1
• 90 citations
  Extracellular vesicles and nanoparticles: emerging complexities.
  Dennis K Jeppesen, Qin Zhang, Jeffrey L Franklin, Robert J Coffey> ;Trends in Cell Biology. 2023 Aug 1
• 10 citations
  Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research.
  Bogdan Mateescu, Jennifer C Jones, Roger P Alexander, Eric Alsop, Ji Yeong An, Mohammad Asghari, Alex Boomgarden, Laura Bouchareychas, Alfonso Cayota, Hsueh-Chia Chang...> ;Iscience. 2022 Aug 19
• 30 citations
  Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice.
  Julia L Drewes, Jie Chen, Nicholas O Markham, Reece J Knippel, Jada C Domingue, Ada J Tam, June L Chan, Lana Kim, Madison McMann, Courtney Stevens, Christine M Dejea, ...> ;Cancer Discovery. 2022 Aug 5
• 8 citations
  Recent Advances in the Study of Extracellular Vesicles in Colorectal Cancer.
  Sarah E Glass, Robert J Coffey> ;Gastroenterology. 2022 Nov 1
• 62 citations
  Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates mA-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression.
  Hao Liu, Danxiu Li, Lina Sun, Hongqiang Qin, Ahui Fan, Lingnan Meng, Ramona Graves-Deal, Sarah E Glass, Jeffrey L Franklin, Qi Liu, Jing Wang, Timothy J Yeatman, Hao G...> ;Molecular Cancer. 2022 Mar 12
• 1 citations
  Significance of a calcium-binding protein S100A14 expression in colon cancer progression.
  Hiroki Hashida, Robert J Coffey> ;Journal of Gastrointestinal Oncology. 2022 Feb 1
• 97 citations
  Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.
  Bob Chen, Cherie' R Scurrah, Eliot T McKinley, Alan J Simmons, Marisol A Ramirez-Solano, Xiangzhu Zhu, Nicholas O Markham, Cody N Heiser, Paige N Vega, Andrea Rolong, ...> ;Cell. 2021 Dec 22
• 144 citations
  Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.
  Qin Zhang, Dennis K Jeppesen, James N Higginbotham, Ramona Graves-Deal, Vincent Q Trinh, Marisol A Ramirez, Yoojin Sohn, Abigail C Neininger, Nilay Taneja, Eliot T McK...> ;Nature Cell Biology. 2021 Dec 1
• 65 citations
  MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging
  Denis Schapiro, Artem Sokolov, Clarence Yapp, Yu-An Chen, Jeremy L. Muhlich, Joshua Hess, Allison L. Creason, Ajit J. Nirmal, Gregory J. Baker, Maulik K. Nariya, Jia-R...> ;Nature Methods. 2021 Nov 25
• 18 citations
  Translocator protein-targeted photodynamic therapy for direct and abscopal immunogenic cell death in colorectal cancer.
  Qing Xie, Zhen Li, Yang Liu, Dawei Zhang, Meng Su, Hiroaki Niitsu, Yuanyuan Lu, Robert J. Coffey, Mingfeng Bai> ;Acta Biomaterialia. 2021 Jul 27
• 3 citations
  Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3.
  Alina Starchenko, Ramona Graves-Deal, Douglas K. Brubaker, Cunxi Li, Yu-Ping Yang, Bhuminder Singh, Robert J. Coffey, Douglas A. Lauffenburger> ;Integrative Biology. 2021 Jun 15
• 1 citations
  Cell-autonomous role of EGFR in spontaneous duodenal tumors in LRIG1 null mice
  Hiroaki Niitsu, Yuanyuan Lu, Won Jae Huh, Anna M. Love, Jeffrey L. Franklin, Robert J. Coffey> ;Cellular and Molecular Gastroenterology and Hepatology. 2021 May 11
• 10 citations
  First-in-human PET imaging and estimated radiation dosimetry of L-[5-11C]-glutamine in patients with metastatic colorectal cancer
  Allison S Cohen, Joe Grudzinski, Gary T. Smith, Todd E. Peterson, Jennifer G. Whisenant, Tiffany L Hickman, Kristen K. Ciombor, Dana Backlund Cardin, Cathy Eng, Laura ...> ;Journal of Nuclear Medicine. 2021 Apr 30
• 22 citations
  Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer.
  Allison S. Cohen, Ling Geng, Ping Zhao, Allie Fu, Michael L. Schulte, Ramona Graves-Deal, M. Kay Washington, Jordan Berlin, Robert J. Coffey, H. Charles Manning> ;Translational Oncology. 2020 Oct 1
• 16 citations
  A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin
  Jumpei Kondo, Won Jae Huh, Jeffrey L. Franklin, Michael Heinrich, Brian P. Rubin, Robert J. Coffey> ;The Journal of Pathology. 2020 Sep 17
• 99 citations
  Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation
  Amrita Banerjee, Charles A. Herring, Bob Chen, Hyeyon Kim, Alan J. Simmons, Austin N. Southard-Smith, Margaret M. Allaman, James R. White, Mary C. Macedonia, Eliot T. ...> ;Gastroenterology. 2020 Dec 1
• 13 citations
  Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and regeneration
  Xiao Zhang, Sheila Bandyopadhyay, Leandro Pires Araujo, Kevin Tong, Juan Flores, Daniel Laubitz, Yanlin Zhao, George S. Yap, Jingren Wang, Qingze Zou, Ronaldo P. Ferra...> ;JCI Insight. 2020 Aug 20
• 1 citations
  Stanley Cohen (1922-2020).
  Graham Carpenter, Robert J. Coffey> ;Science. 2020 Mar 20
• 4 citations
  Molecular Imaging of Inflammation in Osteoarthritis Using a Water-Soluble Fluorocoxib
  Jashim Uddin, Anoop Vemulapalli, Hiroaki Niitsu, Brenda C. Crews, Connor G Oltman, Philip J. Kingsley, Taylor E. Kavanaugh, Sean K. Bedingfield, J. Oliver McIntyre, Ma...> ;ACS Medicinal Chemistry Letters. 2020 Feb 24
• 25 citations
  Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core
  J. Tian, K.B. Teuscher, Erin R. Aho, Joseph Alvarado, Jonathan J. Mills, K.M. Meyers, Rocco D. Gogliotti, Chao Han, Jonathan David Macdonald, Jiqing Sai, J.G. Shaw, Jo...> ;Journal of Medicinal Chemistry. 2020 Jan 23
• 1507 citations
  Reassessment of Exosome Composition
  Dennis K. Jeppesen, Aidan M. Fenix, Jeffrey L. Franklin, James N. Higginbotham, Qin Zhang, Lisa J. Zimmerman, Daniel C. Liebler, Jie Ping, Qi Liu, Rachel Evans, Willia...> ;Cell. 2019 Apr 4
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