RobertLanglandEilMD

PubMed

• Intracellular K+ Limits T-cell Exhaustion and Preserves Antitumor Function.
  Collier, C., Wucherer, K., McWhorter, M., Jenkins, C., Bartlett, A., Roychoudhuri, R., Eil, R.> ;Cancer Immunology Research. 2024 Jan 3
• Updated Management of Colorectal Cancer Liver Metastases: Scientific Advances Driving Modern Therapeutic Innovations.
  Ranish K Patel, Shahrose Rahman, Issac R Schwantes, Alexandra Bartlett, Robert Eil, Khashayar Farsad, Kathryn Fowler, Shaun M Goodyear, Lissi Hansen, Adel Kardosh, Nim...> ;Cellular and Molecular Gastroenterology and Hepatology. 2023 Jan 1
• 7 citations
  Hepatectomy is associated with improved oncologic outcomes in recurrent colorectal liver metastases: A propensity-matched analysis.
  Thomas L Sutton, Liam H Wong, Brett S Walker, Elizabeth N Dewey, Robert Eil, Charles D Lopez, Adel Kardosh, Emerson Y Chen, Flavio G Rocha, Kevin G Billingsley, Skye C...> ;Surgery. 2023 Jun 1
• 3 citations
  Surgical timing after preoperative chemotherapy is associated with oncologic outcomes in resectable colorectal liver metastases.
  Thomas L Sutton, Liam H Wong, Brett S Walker, Elizabeth N Dewey, Robert L Eil, Uchechukwu Ibewuike, Emerson Y Chen, Flavio G Rocha, Kevin G Billingsley, Skye C Mayo> ;Journal of Surgical Oncology. 2022 Jun 1
• 1 citations
  Conventional hepatic arterial anatomy? Novel findings and insights of a multi-disciplinary hepatic arterial infusion pump program.
  Brett S. Walker, Thomas L. Sutton, Robert L. Eil, Elena K. Korngold, Kenneth J. Kolbeck, Kevin G. Billingsley, Skye C. Mayo> ;American Journal of Surgery. 2021 Jun 1
• 38 citations
  CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function.
  Sarah K. Whiteside, Francis M. Grant, David Gyori, Alberto G. Conti, Charlotte J. Imianowski, Paula Kuo, Rabab Nasrallah, Firas Sadiyah, Sergio A. Lira, Frank Tacke, R...> ;Immunology. 2021 Apr 10
• 10 citations
  Surgical and oncologic outcomes following repeat hepatic resection of colorectal liver metastasis: Who benefits?
  Liam H. Wong, Thomas L. Sutton, Brett S. Walker, Charles D. Lopez, Adel Kardosh, Robert L. Eil, Emerson Y. Chen, Kevin G. Billingsley, Skye C. Mayo> ;American Journal of Surgery. 2021 Mar 8
• 37 citations
  BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression
  Francis M. Grant, Jie Yang, Rabab Nasrallah, James Clarke, Firas Sadiyah, Sarah K. Whiteside, Charlotte J. Imianowski, Paula Kuo, Panagiota Vardaka, Tihomir Todorov, N...> ;The Journal of Experimental Medicine. 2020 Sep 7
• 78 citations
  Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies.
  Devikala Gurusamy, Amanda N. Henning, Tori N. Yamamoto, Zhiya Yu, Nikolaos Zacharakis, Sri Krishna, Rigel J. Kishton, Suman K. Vodnala, Arash Eidizadeh, Li Jia, Christ...> ;Cancer Cell. 2020 Jun 8
• 89 citations
  T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy
  Tori N. Yamamoto, Ping-Hsien Lee, Suman K. Vodnala, Devikala Gurusamy, Rigel J. Kishton, Zhiya Yu, Arash Eidizadeh, Robert L. Eil, Jessica Fioravanti, Luca Gattinoni, ...> ;The Journal of Clinical Investigation. 2019 Apr 1
• 288 citations
  T cell stemness and dysfunction in tumors are triggered by a common mechanism.
  Suman K. Vodnala, Robert L. Eil, Rigel J. Kishton, Madhusudhanan Sukumar, Tori N. Yamamoto, Ngoc Han Ha, Ping-Hsien Lee, Min Hwa Shin, Shashank J. Patel, Zhiya Yu, Dou...> ;Science. 2019 Mar 29
• 126 citations
  Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy.
  Christopher A. Klebanoff, Joseph G. Crompton, Anthony J. Leonardi, Tori N. Yamamoto, Smita S. Chandran, Robert L. Eil, Madhusudhanan Sukumar, Suman K. Vodnala, Jinhui ...> ;JCI Insight. 2017 Dec 7
• 544 citations
  Identification of essential genes for cancer immunotherapy
  Shashank J. Patel, Neville E. Sanjana, Rigel J. Kishton, Arash Eidizadeh, Suman K. Vodnala, Maggie Cam, Jared J. Gartner, Li Jia, Seth M. Steinberg, Tori N. Yamamoto, ...> ;Nature. 2017 Aug 31
• 41 citations
  Novel “Elements” of Immune Suppression within the Tumor Microenvironment
  Devikala Gurusamy, David Clever, Robert L. Eil, Nicholas P. Restifo> ;Cancer Immunology Research. 2017 Jun 1
• 39 citations
  Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction.
  Anthony C. Cruz, Madhu Ramaswamy, Claudia Ouyang, Christopher A. Klebanoff, Prabuddha Sengupta, Tori N. Yamamoto, Françoise Meylan, Stacy K. Thomas, Nathan Richoz, Rob...> ;Nature Communications. 2016 Dec 23
• 394 citations
  Ionic immune suppression within the tumour microenvironment limits T cell effector function
  Robert L. Eil, Suman K. Vodnala, David Clever, Christopher A. Klebanoff, Madhusudhanan Sukumar, Jenny H. Pan, Douglas C. Palmer, Alena Gros, Tori N. Yamamoto, Shashank...> ;Nature. 2016 Sep 22
• 174 citations
  Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche
  David Clever, Rahul Roychoudhuri, Michael G. Constantinides, Michael H. Askenase, Madhusudhanan Sukumar, Christopher A. Klebanoff, Robert L. Eil, Heather D. Hickman, Z...> ;Cell. 2016 Aug 25
• 181 citations
  BACH2 regulates CD8 + T cell differentiation by controlling access of AP-1 factors to enhancers
  Rahul Roychoudhuri, David Clever, Peng Li, Yoshiyuki Wakabayashi, Kylie M. Quinn, Christopher A. Klebanoff, Yun Ji, Madhusudhanan Sukumar, Robert L. Eil, Zhiya Yu, Ros...> ;Nature Immunology. 2016 Jul 1
• 3 citations
  Significance of preoperative radiographic pancreatic density in predicting pancreatic fistula after surgery for pancreatic neuroendocrine tumors
  Yasmine Assadipour, Saïd C. Azoury, Nicholas N. Schaub, Young Hong, Robert L. Eil, Seth M. Steinberg, Aradhana M. Venkatesan, Steven K. Libutti, Michael S. Hughes, Suz...> ;American Journal of Surgery. 2016 Jul 1
• 44 citations
  The transcription factor BACH2 promotes tumor immunosuppression
  Rahul Roychoudhuri, Robert L. Eil, David Clever, Christopher A. Klebanoff, Madhusudhanan Sukumar, Francis M. Grant, Zhiya Yu, Gautam U. Mehta, Hui Liu, Ping Jin, Yun J...> ;The Journal of Clinical Investigation. 2016 Feb 1
• 250 citations
  Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy
  Madhusudhanan Sukumar, Jie Liu, Gautam U. Mehta, Shashank J. Patel, Rahul Roychoudhuri, Joseph G. Crompton, Christopher A. Klebanoff, Yun Ji, Peng Li, Zhiya Yu, Greg W...> ;Cell Metabolism. 2016 Jan 12
• 167 citations
  Memory T cell–driven differentiation of naive cells impairs adoptive immunotherapy
  Christopher A. Klebanoff, Christopher D. Scott, Anthony J. Leonardi, Tori N. Yamamoto, Anthony C. Cruz, Claudia Ouyang, Madhu Ramaswamy, Rahul Roychoudhuri, Yun Ji, Ro...> ;The Journal of Clinical Investigation. 2015 Dec 14
• 123 citations
  Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance
  Douglas C. Palmer, Geoffrey Guittard, Zulmarie Franco, Joseph G. Crompton, Robert L. Eil, Shashank J. Patel, Yun Ji, Nicholas J. Van Panhuys, Christopher A. Klebanoff,...> ;The Journal of Experimental Medicine. 2015 Nov 16
• 97 citations
  The interplay of effector and regulatory T cells in cancer.
  Rahul Roychoudhuri, Robert L. Eil, Nicholas P. Restifo> ;Current Opinion in Immunology. 2015 Apr 1
• 243 citations
  Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics
  Joseph G. Crompton, Madhusudhanan Sukumar, Rahul Roychoudhuri, David Clever, Alena Gros, Robert L. Eil, Eric Tran, Ken-ichi Hanada, Zhiya Yu, Douglas C. Palmer, Sid P....> ;Cancer Research. 2015 Jan 15
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