RobertJFoxMD

Neurology • Cleveland, OH

Associate Professor, Medicine, Case Western Reserve University School of Medicine

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Office
9500 Euclid Ave
Cleveland, OH 44195
Phone+1 800-223-2273
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Education & Training

University of Pennsylvania Health SystemResidency, Neurology, 1996 - 2000
Johns Hopkins University School of MedicineClass of 1996

Certifications & Licensure

OH State Medical License 2000 - 2025
PA State Medical License 1997 - 2002
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011, 2013

Publications & Presentations

PubMed

Clinical trials for progressive multiple sclerosis: progress, new lessons learned, and remaining challenges.
Jeremy Chataway, Thomas Williams, Vivien Li, Ruth Ann Marrie, Daniel Ontaneda, Robert J Fox> ;The Lancet. Neurology. 2024 Mar 1
Pathophysiology, Diagnosis, Treatment and Emerging Neurotherapeutic Targets for Progressive Multiple Sclerosis: The Age of PIRA.
Alise K Carlson, Robert J Fox> ;Neurologic Clinics. 2024 Feb 1
Ibudilast reduces slowly enlarging lesions in progressive multiple sclerosis.
Kunio Nakamura, Bhaskar Thoomukuntla, James Bena, Jeffrey A Cohen, Robert J Fox, Daniel Ontaneda> ;Multiple Sclerosis. 2024 Mar 1
Serum macrophage migration inhibitory factor levels predict brain atrophy in people with primary progressive multiple sclerosis.
Dimitrios C Ladakis, Maria I Reyes-Mantilla, Sachin P Gadani, Jackson W Mace, Susana C Dominguez-Penuela, Mayaa J Appiah, Matthew D Smith, Pavan Bhargava, Robert J Fox...> ;Multiple Sclerosis. 2024 Jan 1
1 citations
Effect of ibudilast on thalamic magnetization transfer ratio and volume in progressive multiple sclerosis.
Kunio Nakamura, Yufan Zheng, Kedar R Mahajan, Jeffrey A Cohen, Robert J Fox, Daniel Ontaneda> ;Multiple Sclerosis. 2023 Sep 1
Assisted ambulation to improve health outcomes for older medical inpatients (AMBULATE): study protocol for a randomized controlled trial.
Joshua K Johnson, Aaron C Hamilton, Bo Hu, Quinn R Pack, Peter K Lindenauer, Robert J Fox, Ardeshir Hashmi, Lee Anne Siegmund, Christian N Burchill, Glen B Taksler, To...> ;Trials. 2023 Jul 24
16 citations
Risk of new disease activity in patients with multiple sclerosis who continue or discontinue disease-modifying therapies (DISCOMS): a multicentre, randomised, single-b...
John R Corboy, Robert J Fox, Ilya Kister, Gary R Cutter, Charity J Morgan, Rebecca Seale, Eric Engebretson, Tarah Gustafson, Aaron E Miller> ;The Lancet. Neurology. 2023 Jul 1
1 citations
The impact of cigarette smoking on cognitive processing speed and brain atrophy in multiple sclerosis.
Ebtesam Alshehri, Jeffrey A Cohen, Daniel Ontaneda, Kunio Nakamura, Scott Husak, Thomas E Love, Robert J Fox, Farren Bs Briggs, Devon S Conway> ;Multiple Sclerosis. 2023 Jun 1
1 citations
Effects of baseline age and disease duration on the efficacy and safety of siponimod in patients with active SPMS: Post hoc analyses from the EXPAND study.
Le H Hua, Amit Bar-Or, Stanley L Cohan, Fred D Lublin, Patricia K Coyle, Bruce Ac Cree, Xiangyi Meng, Wendy Su, Gina Mavrikis Cox, Robert J Fox> ;Multiple Sclerosis and Related Disorders. 2023 Jul 1
Severity and worsening of fatigue among individuals with multiple sclerosis.
Amber Salter, Alexander Keenan, Hoa H Le, Kavita Gandhi, Maria Ait-Tihyaty, Samantha Lancia, Gary R Cutter, Robert J Fox, Ruth Ann Marrie> ;Multiple Sclerosis Journal - Experimental, Translational and Clinical. 2023 Apr 18
Long-Term Effectiveness and Safety of Natalizumab in African American and Hispanic/Latino Patients with Early Relapsing-Remitting Multiple Sclerosis: STRIVE Data Analy...
Jai Perumal, Roumen Balabanov, Laura Balcer, Steven Galetta, Zhaonan Sun, Hanyue Li, Danette Rutledge, Robin L Avila, Robert J Fox> ;Neurology and Therapy. 2023 Jun 1
3 citations
Treatment preferences in relation to fatigue of patients with relapsing multiple sclerosis: A discrete choice experiment.
Tommi Tervonen, Robert J Fox, Anne Brooks, Tatiana Sidorenko, Neli Boyanova, Bennett Levitan, Brian Hennessy, Andrea Phillips-Beyer> ;Multiple Sclerosis Journal - Experimental, Translational and Clinical. 2023 Jan 23
1 citations
Attitudes of people with multiple sclerosis toward brain donation.
Ruth Ann Marrie, Leanne Kosowan, Gary R Cutter, Robert J Fox, Amber Salter> ;Frontiers in Neurology. 2023 Jan 1
1 citations
The relevance of fatigue to relapse rate in multiple sclerosis: Applying patient preference data to the OPTIMUM trial.
Robert J Fox, Tommi Tervonen, Andrea Phillips-Beyer, Tatiana Sidorenko, Neli Boyanova, Anne Brooks, Brian Hennessy, Carol Jamieson, Bennett Levitan> ;Multiple Sclerosis. 2023 Mar 1
2 citations
COVID-19 in the pregnant or postpartum MS patient: Symptoms and outcomes.
Amber Salter, Anne H Cross, Gary R Cutter, Robert J Fox, David K B Li, Bruce Bebo, June Halper, Pamela Kanellis, Kottil Rammohan, Scott D Newsome> ;Multiple Sclerosis and Related Disorders. 2022 Sep 1
8 citations
Physical and Mental Health-Related Quality of Life Trajectories Among People With Multiple Sclerosis.
Julia O'Mahony, Amber Salter, Robert J Fox, Gary R Cutter, Ruth Ann Marrie, Ciftci-Kavaklioglu, B.> ;Neurology. 2022 Oct 3
7 citations
A double-blind, randomized, placebo-controlled phase 2 trial evaluating the selective dihydroorotate dehydrogenase inhibitor vidofludimus calcium in relapsing-remittin...
Robert J Fox, Heinz Wiendl, Christian Wolf, Nicola De Stefano, Johann Sellner, Viktoriia Gryb, Konrad Rejdak, Plamen Stoyanov Bozhinov, Nataliya Tomakh, Iryna Skrypche...> ;Annals of Clinical and Translational Neurology. 2022 Jul 1
6 citations
Real-world disease-modifying therapy pathways from administrative claims data in patients with multiple sclerosis.
Robert J Fox, Rina Mehta, Timothy Pham, Julie Park, Kathleen Wilson, Machaon Bonafede> ;BMC Neurology. 2022 Jun 7
6 citations
Siponimod vs placebo in active secondary progressive multiple sclerosis: a post hoc analysis from the phase 3 EXPAND study.
Ralf Gold, Daniela Piani-Meier, Ludwig Kappos, Amit Bar-Or, Patrick Vermersch, Gavin Giovannoni, Robert J Fox, Douglas L Arnold, Ralph H B Benedict, Iris-Katharina Pen...> ;Journal of Neurology. 2022 Sep 1
7 citations
Attitudes toward coronavirus disease 2019 vaccination in people with multiple sclerosis.
Ruth Ann Marrie, Casandra Dolovich, Gary R Cutter, Robert J Fox, Amber Salter> ;Multiple Sclerosis Journal - Experimental, Translational and Clinical. 2022 May 22
16 citations
Long-term efficacy and safety of siponimod in patients with secondary progressive multiple sclerosis: Analysis of EXPAND core and extension data up to >5 years.
Bruce Ac Cree, Douglas L Arnold, Robert J Fox, Ralf Gold, Patrick Vermersch, Ralph Hb Benedict, Amit Bar-Or, Daniela Piani-Meier, Nicolas Rouyrre, Shannon Ritter, Ajay...> ;Multiple Sclerosis. 2022 Sep 1
15 citations
Effect of siponimod on magnetic resonance imaging measures of neurodegeneration and myelination in secondary progressive multiple sclerosis: Gray matter atrophy and ma...
Douglas L Arnold, Daniela Piani-Meier, Amit Bar-Or, Ralph Hb Benedict, Bruce Ac Cree, Gavin Giovannoni, Ralf Gold, Patrick Vermersch, Sophie Arnould, Frank Dahlke, Tho...> ;Multiple Sclerosis. 2022 Sep 1
DMTs should be trialed in individuals with PPMS and SPMS with or without recent disease activity - Commentary.
Robert J Fox, Mar Tintore> ;Multiple Sclerosis. 2022 Feb 1
1 citations
A Survey of Cannabis Use in a Large US-Based Cohort of People with Multiple Sclerosis.
Amber Salter, Robert J Fox, Gary Cutter, Ruth Ann Marrie, Kate E Nichol, Joshua R Steinerman, Karry M J Smith> ;International Journal of MS Care. 2021 Dec 29
12 citations
NARCOMS and Other Registries in Multiple Sclerosis: Issues and Insights.
Ruth Ann Marrie, Gary R Cutter, Robert J Fox, Timothy Vollmer, Tuula Tyry, Amber Salter> ;International Journal of MS Care. 2021 Dec 29
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Press Mentions

Cannabis Use Common Among People with MSOctober 28th, 2021
Serum NfL Not Linked to Disease Progression in RRMS Patients on NatalizumabSeptember 17th, 2021
Newly Approved MS Drug Ponvory Reduces Fatigue, Study ShowsApril 21st, 2021
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Grant Support

Brain Atrophy/Diffusion Tensor Study/Multiple SclerosisNational Institute Of Neurological Disorders And Stroke2005–2008
Brain Atrophy/Diffusion Tensor Study/Multiple SclerosisNational Institute Of Neurological Disorders And Stroke2004