RobertDuncanHiteMD

PubMed

• 12 citations
  Biological Effects of Intravenous Vitamin C on Neutrophil Extracellular Traps and the Endothelial Glycocalyx in Patients with Sepsis-Induced ARDS.
  Xian Qiao, Markos G Kashiouris, Michael L'Heureux, Bernard J Fisher, Stefan W Leichtle, Jonathon D Truwit, Rahul Nanchal, Robert Duncan Hite, Peter E Morris, Greg S Ma...> ;Nutrients. 2022 Oct 21
• 1 citations
  Exercise-induced alterations in phospholipid hydrolysis, airway surfactant, and eicosanoids and their role in airway hyperresponsiveness in asthma.
  Ryan C. Murphy, Ying Lai, James D. Nolin, Robier Aguillon Prada, Arindam Chakrabarti, Michael Novotny, Michael C. Seeds, William A. Altemeier, Michael H. Gelb, Robert ...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2021 Feb 3
• Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.
  Moss, M.,Huang, D. T.,Brower, R. G.,Ferguson, N. D.,Ginde, A. A.,Gong, M. N.,Grissom, C. K.,Gundel, S.,Hayden, D.,Hite, R. D.,Hou, P. C.,Hough, C. L.,Iwashyna, T. J.,K...> ;N. Engl. J. Med.. 2019 May 22
• 2 citations
  Erratum for Drusano et al., "Dilution Factor of Quantitative Bacterial Cultures Obtained by Bronchoalveolar Lavage in Patients with Ventilator-Associated Bacterial Pne...
  George L. Drusano, Michael L. Corrado, Gino Girardi, Evelyn J. Ellis-Grosse, Richard G. Wunderink, Helen K. Donnelly, Kenneth V. Leeper, Mona Brown, Tasnova Malek, Rob...> ;Antimicrobial Agents and Chemotherapy. 2018 Mar 27
• 12 citations
  Dilution Factor of Quantitative Bacterial Cultures Obtained by Bronchoalveolar Lavage in Patients with Ventilator-Associated Bacterial Pneumonia.
  George L. Drusano, Michael L. Corrado, Gino Girardi, Evelyn J. Ellis-Grosse, Richard G. Wunderink, Helen K. Donnelly, Kenneth V. Leeper, Mona Brown, Tasnova Malek, Rob...> ;Antimicrobial Agents and Chemotherapy. 2017 Dec 21
• 240 citations
  Standardized Rehabilitation and Hospital Length of Stay Among Patients With Acute Respiratory Failure: A Randomized Clinical Trial
  Peter E. Morris, Michael J. Berry, D. Clark Files, J. Clifton Thompson, Jordan I. Hauser, Lori Flores, Sanjay Dhar, Elizabeth Chmelo, James Lovato, L. Douglas Case, Ri...> ;JAMA. 2016 Jun 28
• TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis.
  Scheraga, R. G.,Abraham, S.,Niese, K. A.,Southern, B. D.,Grove, L. M.,Hite, R. D.,McDonald, C.,Hamilton, T. A.,Olman, M. A.> ;J. Immunol.. 2015 Nov 26
• Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome*.
  Grissom, C. K.,Hirshberg, E. L.,Dickerson, J. B.,Brown, S. M.,Lanspa, M. J.,Liu, K. D.,Schoenfeld, D.,Tidswell, M.,Hite, R. D.,Rock, P.,Miller, R. R.,Morris, A. H.> ;Crit. Care Med.. 2015 Jan 20
• 1 citations
  Increasing incidence of prolonged acute mechanical ventilation: can we bend the utilization curve?
  Mark L. Metersky, Robert Duncan Hite> ;Critical Care Medicine. 2012 Jan 1
• Surfactant Protein B Inhibits Secretory Phospholipase A2 Hydrolysis of Surfactant Phospholipids.
  Hite, R.D., Grier, B.L., Waite, B.M., Veldhuizen, R.W., Possmayer, F., Yao, L., Seeds, M.C.> ;Am J Physiol Lung Cell Mol Physiol. 2012 Jan 15
• Lysophospholipid and fatty acid inhibition of pulmonary surfactant: non-enzymatic models of phospholipase A2 surfactant hydrolysis.
  Hite, R. D., Seeds, M. C., Jacinto, R. B., Grier, B. L., Waite, B. M., Bass, D. A.> ;Biochim Biophys Acta. 2005 Dec 30
• Hydrolysis of surfactant-associated phosphatidylcholine by mammalian secretory phospholipases A2.
  Hite, R. D., Seeds, M. C., Jacinto, R. B., Balasubramanian, R., Waite, M., Bass, D.> ;Am J Physiol. 1998 Oct
• Human eosinophil group IID secretory phospholipase A2 causes surfactant dysfunction.
  Seeds, M. C., Bowton, D. L., Hite, R. D., Gyves, J. I., Bass, D. A.> ;Chest. 2003 Mar
• Lysophospholipid generation and phosphatidylglycerol depletion in phospholipase A(2)-mediated surfactant dysfunction.
  Hite, R. D., Seeds, M. C., Safta, A. M., Jacinto, R. B., Gyves, J. I., Bass, D. A., Waite, B. M.> ;Am J Physiol Lung Cell Mol Physiol. 2005 Apr
• Surfactant phospholipid changes after antigen challenge: a role for phosphatidylglycerol in dysfunction.
  Hite, R. D., Seeds, M. C., Bowton, D. L., Grier, B. L., Safta, A. M., Balkrishnan, R., Waite, B. M., Bass, D. A.> ;Am J Physiol Lung Cell Mol Physiol. 2005 Apr
• Early intensive care unit mobility therapy in the treatment of acute respiratory failure.
  Morris, P. E., Goad, A., Thompson, C., Taylor, K., Harry, B., Passmore, L., Ross, A., Anderson, L., Baker, S., Sanchez, M., Penley, L., Howard, A., Dixon, L., Leach, S...> ;Crit Care Med. 2008 Aug
• 76 citations
  Venous air embolism from central venous catheterization: a need for increased physician awareness.
  E. W. Ely, R. D. Hite, A. M. Baker, Margaret M. Johnson, David L. Bowton, Edward F. Haponik> ;Critical Care Medicine. 1999 Oct 1
• Acute respiratory distress syndrome: pharmacological treatment options in development.
  Hite, R. D., Morris, P. E.> ;Drugs. 2001
• Relationship between the inflammation and coagulation pathways in patients with severe sepsis: implications for therapy with activated protein C.
  Morris, P. E., Hite, R. D., Ohl, C.> ;BioDrugs. 2002
• Abnormalities in lung surfactant in horses clinically affected with recurrent airway obstruction (RAO).
  Christmann, U., Welles, E. G., Waldridge, B. M., Schumacher, J., Grier, B. L., Hite, R. D.> ;J Vet Intern Med. 2008 Nov 01
• Receiving early mobility during an intensive care unit admission is a predictor of improved outcomes in acute respiratory failure.
  Morris, P. E., Griffin, L., Berry, M., Thompson, C., Hite, R. D., Winkelman, C., Hopkins, R. O., Ross, A., Dixon, L., Leach, S., Haponik, E.> ;Am J Med Sci. 2011 May
• Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status.
  Rice, T. W., Ware, L. B., Haponik, E. F., Chiles, C., Wheeler, A. P., Bernard, G. R., Steingrub, J. S., Hite, R. D., Matthay, M. A., Wright, P., Ely, E. W.> ;Crit Care. 2011
• Lung surfactant function and composition in neonatal foals and adult horses.
  Christmann, U., Livesey, L. C., Taintor, J. S., Waldridge, B. M., Schumacher, J., Grier, B. L., Hite, R. D.> ;J Vet Intern Med. 2006 Nov 01
• Comparison of two fluid-management strategies in acute lung injury.
  Wiedemann, H. P., Wheeler, A. P., Bernard, G. R., Thompson, B. T., Hayden, D., deBoisblanc, B., Connors, A. F., Hite, R. D., Harabin, A. L.> ;N Engl J Med. 2006 Jun 15
• Pulmonary type II cell hypertrophy and pulmonary lipoproteinosis are features of chronic IL-13 exposure.
  Homer, R. J., Zheng, T., Chupp, G., He, S., Zhu, Z., Chen, Q., Ma, B., Hite, R. D., Gobran, L. I., Rooney, S. A., Elias, J. A.> ;Am J Physiol Lung Cell Mol Physiol. 2002 Jul
• Join now to see all

Journal Articles

• Rosuvastatin for Sepsis-Associated Acute Respiratory Distress Syndrome  
  National Heart, Lung, and Blood Institute ARDS Clinical Trials Network, Hite RD, N Eng J Med, 1/1/2014
• Predictting acute lung injury resolution: a role of chest CT?  
  Files DC, Hite RD, Crit Care Med, 1/1/2013
• the impact of hospital-wide use of a tapered cuff endotracheal tube on VAP incidence  
  Bowton DL, Hite RD, Martin RS, Sherertz R, Respir Care, 1/1/2013
• Secretory phospholipase A2 mediated depletion of phosphoatidylglycerol in early acute repiratory distress syndrome  
  Seeds MC, Grier BL, Suckling BN, Safta AM, Long DL, Waite BM, Morris PE, Hite RD, Am J Med Sci, 1/1/2012
• Point: Should positive end-expiratory pressure in patients with ARDS be set on oxygenation? Yes  
  Miller RR, Macintyre NR, Hite RD, Brower RG, Morris AH, Chest, 1/1/2012
• Randomized placebo-controlled clinical trial of an aerosolized beta2-Agonist for Treatment of Acute Lung Injury  
  NHLBI ARDS Clincal Trials Network, Matthay MA, Bower RG, Carson S, Douglas IS, Eisner M, Hite RD, Holets S, Kallet RH, Liu KD, MacIntyre N, Moss M, Schoenfeld D, Stein..., Am J Respir Crit Care Med, 1/1/2011
• Response: Evidence and Experience in Exttracorporeal Membrane Oxygenation  
  Morris AH, Hirshberg E, Miller RR, Statler KD, Hite RD, Chest, 1/1/2011
• Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status  
  Rice TW, Ware LB, Haponik EF, Chiles C, Wheeler AP, Bernard GR, Steingrub JS, Hite RD, Matthay MA, Wright P and Ely EW for the NHLBI ARDS Network, Critical Care, 1/1/2011
• Enteral Omega-3 Fatty Acid, -Linolenic Acid, and Antioxidant supplementation in Acute Lung Injury  
  NHLBI ARDS Clincal Trials Network (Hite RD), JAMA, 1/1/2011
• Surfactant alterations in horses with recurrent airway obstruction at various clinical stages  
  Christmann U, Hite RD, Tan RH, Thatcher CD, Witonsky SG, Were SR, Buechner-Maxwell VA, Am J Vet Res, 1/1/2010
• Counterpoint: Efficacy of extracorporeal membrane oxygenation in 2009 influenza (H1N1): Sufficient evidence?  
  Morris AH, Hirshberg E, Miller RR, Statler KD, Hite RD, Chest, 1/1/2010
• Role of lung surfactant in respiratory disease: current knowledge in large animal medicine  
  Christmann U, Buechner-Maxwell VA, Witonsky SG, Hite RD, J Vet Int Med, 1/1/2009
• Surfactant alterations in horses with recurrent airway obstruction at various clinical stages  
  Christmann U, Hite RD, Witonsky SG, Elvinger F, Were SR, Thatcher CD, Tan RH, Buechner-Maxwell VA, J Vet Int Med, 1/1/2009
• Early ICU mobility therapy in the treatment of acute respiratory failure  
  Morris PE, Goad A, Thompson C, Taylor K, Harry B, Hite RD, Haponik EF, Crit Care Med, 1/1/2008
• Multicenter validation of a computer-based clinical decision support toll for glucose control in adult and pediatric intensive care units  
  Thompson BT, Orme JF, Zheng H, Luckett PM, Truwit JD, Willson DF, Hite RD, Brower RG, Bernard GR, Curley MAQ, Steingrub JS, Sorenson DK, Sward K, Hirshberg E, Morris A..., J Diab Sci Tech, 1/1/2008
• Different expression ratio of S100A8/A9 and S100A12 in acute and chronic lung diseases  
  Lorenz E, Muhlebach MS, Tessier PA, Alexis NE, Hite RD, Seeds MC, Peden DB, Meredith W, Resp Med, 1/1/2008
• Differences in Lung Surfactant Function and Composition between Neonatal Foals and Adult Horses  
  Christmann U, Livesay L, Taintor J, Waldridge B, Schumacher J, Grier B, Hite RD, J Vet Int Med, 1/1/2006
• Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome  
  NHLBI ARDS Clinical Trials Network (Hite RD), N Engl J Med, 1/1/2006
• Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury  
  NHLBI ARDS Clinical Trials Network (Hite RD), N Engl J Med, 1/1/2006
• Surfactant phospholipid changes after antigen challenge: A role for phosphatidylglycerol in dysfunction  
  Hite RD, Seeds MC, Bowton DL, Grier BL, Safta AM, Balkrishnan R, Waite BM, Bass DA, Am J Physiol: Lung Cell and Mol Physiol, 1/1/2005
• Lysophospholipid generation and phosphatidylglycerol depletion in phospholipase A2-mediated surfactant dysfunction  
  Hite RD, Seeds MC, Safta AM, Jacinto RB, Gyves JI, Bass DA, Waite BM, Am J Physiol: Lung Cell and Mol Physiol, 1/1/2005
• Lysophospholipid acid inhibition of pulmonary surfactant: non-enzymatic models of phopholipase A2 surfactant hydrolysis  
  Hite RD, Seeds MC, Safta AM, Jacinto RB, Gyves JI, Bass DA, Waite BM, Biochim Biophys Acta, 1/1/2005
• The effect of airway pressure display on inter-observer variability in the assessment of vascular pressures in patients with acute llung injury and ARDS  
  Rizvi K, Fuchs B, Guntupalli K, Hite D, Truwit J, deBoisblanc B, Crit Care Med, 1/1/2005
• Researchers explore new pathways for surfactant therapy  
  Hite RD, Adv Manager Resp Care, 1/1/2003
• Activated protein C as a therapy for severe sepsis  
  Morris PE, Ohl C, Hite RD, Biodrugs, 1/1/2002
• Join now to see all

Books/Book Chapters

• Practical Guide to Mechanical Ventilation. 
  Chapter: Mechanical Ventilation in Restrictive Lung Disease. 
  Page 173 - 192Hite RDEditors: Truwit JD, Epstein SK.Wiley-Blackwell, Hoboken, NJ2011
• Practical Guide to Mechanical Ventilation. 
  Chapter: Modes of Mechanical Ventilation. 
  Page 141 - 162Hite RDEditors: Truwit JD, Epstein SK.Wiley-Blackwell, Hoboken, NJ2011
• Practical Guide to Mechanical Ventilation. 
  Chapter: Ventilator mechanics. 
  Page 133 - 140Bowton DL, Hite RDEditors: Truwit JD, Epstein SK.Wiley-Blackwell, Hoboken, NJ2011
• The Evidenced Based Practice of Critical Care. 
  Chapter: Is Extracorporeal Life Support for Adults with ARDS useful? 
  Page 141 - 150Morris AH, Hirshberg E, Statler KD, Dalton H, Hite RDEditors: Deutschman CS and Neligan P.Saunders Elsevier, Philadelphia, PA2010
• Pocket ICU Management. 
  Chapter: Mechanical Ventilation. 
  Hite RDEditors: Farmer JC, Wall MH.PocketMedicine.com, Inc.2008
• Pocket ICU Management. 
  Chapter: Non-Invasive Ventilation. 
  Hite RDEditors: Farmer JC, Wall MH.PocketMedicine.com, Inc.2008
• Pocket ICU Management. 
  Chapter: Weaning from Mechanical Ventilation. 
  Hite RDEditors: Farmer JC, Wall MH.PocketMedicine.com, Inc.2008
• Pulmonary Surfactant: from molecular biology to clinical practice. 
  Chapter: The adult respiratory distress syndrome: clinical aspects relevant to surfactant supplementation. 
  Page 685 - 703Spragg RG, Gilliard N, Richman P, Smith RM, Hite RD, Pappert D, Heldt G, Merrit TAEditors: Robertson B, Van Gold LMG, Batenburg JJ.Elsevier Medical Publishers, Amsterdam1992
• Join now to see all

Abstracts/Posters

• Predictive Value of Fluid Balance on Extubation Failure.
  Burkhart R, Chatterjee A, Pajewski N, Hite RD, Am J Respir Crit Care Med, 1/1/2013
• Secretory A2 Phospholipase-Mediated Surfactant Depletion In A Non-Lethal Murine Lung Injury Model
  Hite RD, Files DC, Satusky MJ, Ireland LN, Waite BM, Seeds MC, Am J Respir Crit Care Med, 1/1/2013
• The evolution of eProtocols that enable reproducible clinical research and care methods.
  Blagev DP, Hirshberg EL, Sward K, Thompson BT, Brower R, Truwit J, Hite D, Steingrub J, Orme JF Jr, Clemmer TP, Weaver LK, Thomas F, Grisson CK, Sorenson D, Sittig DF,..., J Clin Monit Comput, 1/11/2012
• A Randomized Controlled Trial of Direct Noise Reduction in the ICU.
  Miles M, Hite RD, J Investig Med, 1/1/2012
• Cytokine Regulation of Secretory Phospholipases A2 in a Differentiated Human Monocyte Cell Model.
  Updaw RJ, Hite R, Blair R, Ireland L, Grier B, Waite M, Seeds MC, Am J Respir Crit Care Med, 1/1/2011
• Regulation of secretory A2 phospholipase activity in persistent ARDS.
  Hite RD, Seeds MC, Morris PE, Grier BM, Waite BM, Douglas IS, Hudson LD, Goodman RB, Am J Respir Crit Care Med, 1/1/2009
• Randomized, Placebo-Controlled Trial of an Aerosolized Beta-2 Adrenergic Agonist (Albuterol) for the Treatment of Acute Lung Injury.
  Matthay MA, Brower R, Thompson BT, Schoenfeld D, Eisner MD, Carson S, Moss M, Douglas I, Hite D, MacIntyre N, Liu KD, Am J Respir Crit Care Med, 1/1/2009
• Early ICU Mobility Decreased Hospital Readmissions during 1st Year Post-Hospital Discharge.
  Morris PE, Griffin L, Goad A, Thompson C, Howard A, Harry B, Taylor K, Berr M, Hite R, Winkelman C, Hopkins R, Small R, Haponik EF, Am J Respir Crit Care Med, 1/1/2009
• Early Enteral Intake Is Associated with Improved Outcomes in Acute Lung Injury.
  Rice TW, Stapleton RD, Wheeler AP, Bernard GR, Hite RD, Am J Respir Crit Care Med, 1/1/2009
• Regulation of GP IIA sPLA2 mRNA production in a human monocyte cell model (THP-1)
  Blair RA, Hite RD, Seeds MC, Am J Respir Crit Care Med, 1/1/2008
• Surfactant Alterations in Asthmatics from the Wake Forest Severe Asthma Research Program Center.
  Hite RD, Hastie AT, Seeds MC, Grier BL, Peters SP, Moore WC, Bleecker ER, Am J Respir Crit Care Med, 1/1/2008
• Medical student perspectives on the role of spirituality in end-of-life decision making.
  Cline JA, Foster J, Strong J, Passmore L, King NP, Hite RD, J Investig Med, 1/1/2008
• Surfactant in healthy horses: what are the effects of clinical parameters?
  Christmann U, Tan R, Dryman B, Werrel S, Witonsky S, Thatcher C, Buechner-Maxwell V, Grier B, Hite D, Symposium of the Veterinary Comparative Respiratory Society, Lafayette, IN, 1/1/2007
• The impact of steroids on surfactant in persistent ARDS (ARDSnet LaSRS Trial).
  Hite RD, Seeds MC, Grier BL, Morris PE, Goodman RB, Schoenfeld DA, Proc Am Thorac Soc, 1/1/2006
• Secretory Phospholipase A2 ILA activity in ARDS bronchoalveolar lavage fluid.
  Suckling BN, Hite RD, Bass DA, Seeds MC, Proc Am Thorac Soc, 1/1/2006
• Long term experience with a ventilator weaning protocol.
  Bowton DL, Ely EW, Cox M, Kilgore R, Haponik EF, Hite RD, Proc Am Thorac Soc, 1/1/2005
• Accuracy of airway pressure display for identification of end-expiration during the measurement of CVP and PAOP in mechanically-ventilated patients with ALI/ARDS.
  Friedman D, deBoisblanc B, Arroliga AC, Fuchs B, Guntupalli K, Hite D, Truwit J, Proc Am Thorac Soc, 1/1/2005
• Impact of hydrophobic surfactant proteins on hydrolysis of surfactant phospholipids by secretory A2 phospholipases.
  Hite RD, Seeds MC, Grier BL, Bass DA, Veldhuizen RA, Waite BM, Possmayer F, Proc Am Thorac Soc, 1/1/2005
• Measuring physician practice variability during acute resuscitation of septic shock: a pilot sstudy.
  West JE, Morris PE, Bowton DL, Howard AE, Tidwell CK, Hite RD, Proc Am Thorac Soc, 1/1/2005
• Join now to see all

Lectures

• Mechanical Ventilation 
  1/1/2015
• Acure Respiratory Distress Syndrome 
  1/1/2015
• Surfactant 
  1/1/2015
• Sepsis and Acute Respiratory Distress Syndrome 
  1/1/2015
• VAEs Have Washed Ashore: What's On Board? 
  Winston-Salem, NC - 1/1/2013
• Ethics at the End of Life 
  Winston-Salem, NC - 1/1/2012
• Critical Care Delivery in 2012 and Beyond. 
  University of Louisville, Louisville, KY - 1/1/2012
• Surfactant Abnormalities in Human Lung Diseases 
  University of Louisville, Louisville, KY - 1/1/2012
• Palliative Care in the ICU: Culture Clash? 
  Forsyth Medical Center, Winston-Salem, NC - 1/1/2011
• Challenges to Protocol Compliance in Critical Care 
  Barcelona, Spain - 1/1/2010
• Surfactant in Human Disease 
  Raleigh, NC - 1/1/2010
• Sepsis 
  Rowan Regional Medical Center - 1/1/2010
• Status of Clinical Trials in Acute Lung Injury 
  Universidad Complutense, Madrid, Spain - 1/1/2010
• Pulmonary Vascular Disease 
  1/1/2009
• When Is Enough Enough? 
  Hospice & Palliative Care Center, Winston-Salem, NC - 1/1/2009
• Pressure Targeted Ventilation is NOT Preferred in Severe ARDS 
  San Diego, CA - 1/1/2009
• Surfactant Replacement Therapy in Acute Lung Injury 
  San Diego, CA - 1/1/2009
• ARDS: What do we do now? 
  WFUSM - 1/1/2008
• Venous Thromboembolic Disease 
  1/1/2008
• Recent Trials and Current Trends in the Management of ARDS 
  Baylor College of Medicine, Houston, TX - 1/1/2008
• Surfactant Use in ARDS 
  Honolulu, HI - 1/1/2008
• Fluid Management in ARDS 
  Richmond, VA - 1/1/2008
• Phospholipase-mediated Surfactant Injury in Inflammatory Lung Diseases 
  University of Vermont, Burlington, VT - 1/1/2008
• Diagnosis and Management of Pulmonary Hypertension 
  Winston-Salem, NC - 1/1/2007
• Phospholipase-medicated hydrolysis of surfactant in acute lung injury. 
  Emory University School of Medicine, Atlanta, GA - 1/1/2007
• Join now to see all