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Retired; now Scientist Emeritus5610 Wisconsin Ave. #309Chevy Chase, MD 20815
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Summary
- Main interest: inactivation of bacterial lipopolysaccharides by animals, the enzyme that does it, and its importance for preventing diseases such as colitis and fatty liver.
Also: sepsis pathogenesis
Education & Training
University of Texas Southwestern Medical CenterResidency, Internal Medicine, 1971 - 1972- University of Texas Southwestern Medical Center/Parkland Memorial HospitalInternship, Transitional Year, 1970 - 1971
Harvard Medical SchoolClass of 1970
Oxford UniversityM.A., Physiology, Martin Wronker prize, 1964 - 1967- Vanderbilt UniversityB.A., 1960 - 1964
Mass General Brigham/Massachusetts General Hospital/Brigham and Women's HospitalFellowship, Infectious Disease
Certifications & Licensure
TX State Medical License 1970 - 2022
AOA Board of Internal Medicine Infectious Disease
Awards, Honors, & Recognition
- Member Association of American Physicians, 2005
Publications & Presentations
PubMed
- Acyloxyacyl Hydrolase Prevents Colitis and Colitis-Associated Colorectal Cancer by Inactivating Stimulatory LPS in the Intestine.Lu Gan, Cheng-Yun Yu, Jiayi Chen, Benkun Zou, Zeling Xiao
FASEB Journal. 2025-04-30 - A host enzyme reduces metabolic dysfunction-associated steatotic liver disease (MASLD) by inactivating intestinal lipopolysaccharide.Zhiyan Wang, Nore Ojogun, Yiling Liu, Lu Gan, Zeling Xiao
Elife. 2025-04-24 - 6 citationsA host lipase prevents lipopolysaccharide-induced foam cell formationJintao Feng, Wei Jiang, Xiaofang Cheng, Benkun Zou, Alan W. Varley
Iscience. 2021-08-19
Grant Support
- Interactions Of Endotoxin With Plasma And CellsNational Institute Of Allergy And Infectious Diseases2002–2008
- Interactions Of Endotoxin With Plasma And CellsNational Institute Of Allergy And Infectious Diseases2007
- Endogenously Regulated ImmunomodulationNational Institute Of Allergy And Infectious Diseases1999–2003
- Interactions Of Endotoxin With Plasma And CellsNational Institute Of Allergy And Infectious Diseases1994–2001
- Producing Sepsis Antidote Proteins In VivoNational Institute Of Allergy And Infectious Diseases1995–1998
- Major Histocompatibility Complex In Human DiseaseNational Institute Of Allergy And Infectious Diseases1996
- Interactions Of Endotoxin With Human Plasma And CellsNational Institute Of Allergy And Infectious Diseases1992–1993
- Interactions Of Endotoxin With Human Plasma And CellsNational Institute Of Allergy And Infectious Diseases1985–1991
- Interactions Of Endotoxin With Human Plasma &CellsNational Institute Of Allergy And Infectious Diseases1987–1988
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