RobertLeroySackMD

PubMed

• 12 citations
  Actigraphy-Based Scratch Detection Using Logistic Regression
  Johanna Petersen, Daniel Austin, Robert L. Sack, Tamara L. Hayes> ;IEEE Journal of Biomedical and Health Informatics. 2013 Mar 7
• 10 citations
  Wrist actigraphy for scratch detection in the presence of confounding activities
  Johanna Feuerstein, Daniel Austin, Robert L. Sack, Tamara L. Hayes> ;Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2011 Dec 1
• 18 citations
  Scratching below the surface of sleep and itch
  Robert L. Sack, Jon M. Hanifin> ;Sleep Medicine Reviews. 2010 Dec 1
• 73 citations
  Clinical practice. Jet lag.
  Robert L. Sack> ;The New England Journal of Medicine. 2010 Feb 4
• 1 citations
  Host melatonin secretion is a timing signal for the release of W. bancrofti microfilaria into the circulation.
  Robert L. Sack> ;Medical Hypotheses. 2009 Aug 1
• 49 citations
  The pathophysiology of jet lag
  Robert L. Sack> ;Travel Medicine and Infectious Disease. 2009 Mar 1
• 279 citations
  Circadian Rhythm Sleep Disorders: Part I, Basic Principles, Shift Work and Jet Lag Disorders An American Academy of Sleep Medicine Review
  Robert L. Sack, Dennis Auckley, R. Robert Auger, Mary A. Carskadon, Kenneth P. Wright, Michael V. Vitiello, Irina V. Zhdanova> ;Sleep. 2007 Nov 1
• 259 citations
  Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. An Amer...
  Robert L. Sack, Dennis Auckley, R. Robert Auger, Mary A. Carskadon, Kenneth P. Wright, Michael V. Vitiello, Irina V. Zhdanova> ;Sleep. 2007 Nov 1
• 31 citations
  Relative Coordination to Unknown “Weak Zeitgebers” in Free-Running Blind Individuals:
  Jonathan S. Emens, Alfred J. Lewy, Bryan J. Lefler, Robert L. Sack> ;Journal of Biological Rhythms. 2005 Apr 1
• 43 citations
  Assessment and Management of Insomnia
  Carlos H. Schenck, Mark W. Mahowald, Robert L. Sack> ;JAMA. 2003 May 21
• 24 citations
  Zeitgeber Hierarchy in Humans: Resetting the Circadian Phase Positions of Blind People Using Melatonin
  Alfred J. Lewy, Jonathan S. Emens, Robert L. Sack, Brant P. Hasler, Rebecca A. Bernert> ;Chronobiology International. 2003 Sep 1
• 64 citations
  Low, but not high, doses of melatonin entrained a free-running blind person with a long circadian period.
  Alfred J. Lewy, Jonathan S. Emens, Robert L. Sack, Brant P. Hasler, Rebecca A. Bernert> ;Chronobiology International. 2002 Jan 1
• 26 citations
  Pretreatment circadian period in free-running blind people may predict the phase angle of entrainment to melatonin
  Alfred J. Lewy, Brant P. Hasler, Jonathan S. Emens, Robert L. Sack> ;Neuroscience Letters. 2001 Nov 9
• 65 citations
  Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin
  Alfred J. Lewy, Vance K. Bauer, Brant P. Hasler, Adam R. Kendall, M.Laura N Pires, Robert L. Sack> ;Brain Research. 2001 Nov 9
• 26 citations
  Circadian rhythm sleep disorders: lessons from the blind
  Robert L. Sack, Alfred J. Lewy> ;Sleep Medicine Reviews. 2001 Jun 1
• 29 citations
  Effects of aging on the intrinsic circadian period of totally blind humans.
  Adam R. Kendall, Alfred J. Lewy, Robert L. Sack> ;Journal of Biological Rhythms. 2001 Feb 1
• 274 citations
  Entrainment of free-running circadian rhythms by melatonin in blind people.
  Robert L. Sack, Richard W. Brandes, Adam R. Kendall, Alfred J. Lewy> ;The New England Journal of Medicine. 2000 Oct 12
• 272 citations
  The endogenous melatonin profile as a marker for circadian phase position.
  Alfred J. Lewy, Neil L. Cutler, Robert L. Sack> ;Journal of Biological Rhythms. 1999 Jun 1
• 193 citations
  Morning vs evening light treatment of patients with winter depression
  Alfred J. Lewy, Vance K. Bauer, Neil L. Cutler, Robert L. Sack, Saeeduddin Ahmed, Katherine H. Thomas, Mary L. Blood, Jeanne M. Latham Jackson> ;Archives of General Psychiatry. 1998 Oct 1
• 6 citations
  Percutaneous absorption and model membrane variations of melatonin in aqueous-based propylene glycol and 2-hydroxypropyl-β-cyclodextrin vehicles
  Beom-Jin Lee, Jing Hao Cui, Keith A. Parrott, James W. Ayres, Robert L. Sack> ;Archives of Pharmacal Research. 1998 Oct 1
• 15 citations
  Evaluation of the Actillume® wrist actigraphy monitor in the detection of sleeping and waking
  Miki Matsumoto, Tsutomu Miyagishi, Robert L. Sack, Rod J. Hughes, Mary L. Blood, Alfred J. Lewy> ;Psychiatry and Clinical Neurosciences. 1998 Apr 1
• 68 citations
  Melatonin treatment of winter depression: a pilot study.
  Alfred J. Lewy, Vance K. Bauer, Neil L. Cutler, Robert L. Sack> ;Psychiatry Research. 1998 Jan 16
• 237 citations
  The Human Phase Response Curve (Prc) to Melatonin is About 12 Hours out of Phase with the Prc to Light
  Alfred J. Lewy, Vance K. Bauer, Saeeduddin Ahmed, Katherine H. Thomas, Neil L. Cutler, Clifford M. Singer, Mary Moffit, Robert L. Sack> ;Chronobiology International. 1998 Jan 1
• 137 citations
  The Role of Melatonin and Circadian Phase in Age-related Sleep-maintenance Insomnia: Assessment in a Clinical Trial of Melatonin Replacement
  Rod J. Hughes, Robert L. Sack, Alfred J. Lewy> ;Sleep. 1998 Jan 1
• 59 citations
  Use of melatonin for sleep and circadian rhythm disorders
  Robert L. Sack, Alfred J. Lewy, Rod J. Hughes> ;Annals of Medicine. 1998 Feb 1
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Journal Articles

• Jet Lag  
  Sack, R.L., New England Journal of Medicine, 1/1/2010
• Scratching below the surface of sleep and itch  
  Sack, R.L. and Hanifin, J, Sleep Med Rev, 1/1/2010
• Host melatonin secretion is a timing signal for the release of W bancrofti microfilaria into the circulation  
  Sack, R.L., Medical Hypotheses, 1/1/2009
• The pathophysiology of jet lag  
  Sack, R.L., Travel Medicine and Infectious Disease, 1/1/2009
• Relative coordination to unknown “weak zeitgebers” in free-running blind individuals  
  Emens J.S., Lewy A.J., Lefler B.J. and Sack R.L., J. Biol. Rhyth, 1/1/2005
• Assessment and management of insomnia in medical practice  
  Schenck, C.H., Mahowald, M.W. and Sack, R.L., JAMA, 1/1/2003
• Zeitgeber hierarchy in humans: Resetting the circadian phase positions of blind people using melatonin  
  Lewy A.J., Emens J.S., Sack R.L., Hasler B.P. and Bernert R.A., Chronobiol. Int, 1/1/2003
• Low, but not high, doses of melatonin entrained a free-running blind person with a long circadian period  
  Lewy A.J., Emens J.S., Sack R.L., Hasler B.P. and Bernert R.A, Chronobiol. Int, 1/1/2002
• Identification of free-running rhythms in totally blind children  
  Johnson KP, Cutler NL, Pires M, Sack RL, Lewy AJ, Sleep, 1/1/2002
• Circadian rhythm sleep disorders; Lessons from the blind  
  Sack R.L., Lewy A.J., Brandes R.W., Sleep Medicine Reviews, 1/1/2001
• Capturing the circadian rhythms of free-running blind people with 05 mg melatonin  
  Lewy A.J., Bauer V.K., Hasler B.P., Kendall A.R., Pires M.L.N. and Sack R.L., Brain Research, 1/1/2001
• Pretreatment circadian period in free-running blind people may predict the phase angle of entrainment to melatonin  
  Lewy A.J., Hasler B.P., Emens J.S. and Sack R.L., Neuroscience Letters, 1/1/2001
• Later circadian phase of plasma melatonin relative to usual waketime in older subjects  
  Lewy A.J., Bauer V.K., Singer C.W., Minkunas D.V. and Sack R.L., Sleep, 1/1/2000
• Entrainment of circadian rhythms in a totally blind subject with low dose melatonin  
  Sack R.L., Brandes R.W., Kendall A.R. and Lewy A.J., Sleep, 1/1/2000
• Entrainment of free-running circadian rhythms by melatonin in blind people  
  Sack R.L., Brandes R.W., Kendall, A.R. and Lewy A.J., The New England Journal of Medicine, 1/1/2000
• The endogenous melatonin profile as a marker for circadian phase position  
  Lewy A.J., Cutler N.L., Sack R.L., J Biol Rhyth, 1/1/1999
• Melatonin entrains free-running circadian rhythms in a totally blind person  
  Sack R.L., Brandes R.W., deJongh E.A., Pen S., Nordstrom S., Lewy A.J., Sleep, 1/1/1999
• The acute effects of melatonin administration on sleep in a blind man whose circadian rhythms were inverted  
  Sack R.L., Brandes R.W., deJongh E.A., Pen S., Nordstrom S., Lewy A.J., Sleep, 1/1/1999
• Melatonin treatment of winter depression (WD): a pilot study  
  Hughes R.J., Sack R.L. and Lewy A.J., Sleep, 1/1/1998
• Melatonin treatment of winter depression (WD): a pilot study  
  Lewy A.J., Bauer V.K., Cutler N.L. and Sack R.L., Psychiatry Res, 1/1/1998
• Circadian rhythm sleep disorders in the totally blind  
  Sack R.L., Blood M.L., Hughes R.J. and Lewy A.J., J Vis Impair Blind, 1/1/1998
• Morning versus evening light treatment of winter depressive patients  
  Lewy .J., Bauer V.K., Cutler N.L., Sack R.L., Ahmed S., Thomas K.H., Blood M.L., Jackson J.M.L, Arch Gen Psychiatry, 1/1/1998
• Melatonin synthesis is sharply terminated at the beginning of the circadian day  
  Sack R.L., Hughes R.J., Parrot K., Lewy A.J., Sleep, 1/1/1998
• Low dose melatonin administration and nocturnal activity levels in patients with Alzheimer's disease  
  Singer C.M., Moffit M.T., Colling E.D., Hughes R.J., Cutler N.L., Sack R.L. and Lewy A.J., Sleep Res, 1/1/1997
• Preservation of normal endogenous melatonin profiles in older "low producers"  
  Hughes R.J., Sack R.L., Singer C.M., McArthur A.J. and Lewy A.J., Sleep Res, 1/1/1997
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Books/Book Chapters

• Insomnia, Diagnosis and Treatment 
  Chapter: Insomnnia in Circadian Rhythm Sleep Disorders: Shift Work/Jet Lag/DSP/ASP/Free-Running – Blindness 
  Page 181 - 198Sack, R.LEditors: Sateia, M.J. and Buysse, D.J..Sateia, M.J. and Buysse, D.J., New York, NY2010
• Handbook of Sleep Disorders 
  Chapter: Treatment of Circadian Rhythm Sleep Disorders 
  Page 191 - 205Sack, R.LEditors: Clete A. Kushida.Taylor and Francis, Inc., New York, NYEdition 2nd,2010
• Sleep; A Comprehensive Handbook 
  Chapter: Treatment of Circadian Rhythm Sleep Disorders 
  Page 415 - 422Sack, R.L, and Johnson, KEditors: Lee-Chiong, T.John Wiley and Son, Inc., New York, NY2006
• Psychoneuroendocrinology for the Clinician 
  Chapter: Melatonin as a chronobiotic drug 
  Page 85 - 103Sack R.L., Lewy A.J., Hughes R.J., McArthur A.J. and Blood M.L.Editors: Wolkowitz O.M. and Rothschild A.J..American Psychiatric Press, Washington, DC2003
• Insomnia: Principles and Management 
  Chapter: The sleep promoting effects of melatonin 
  Page 96 - 114Sack R.L., Hughes R.J., Pires M.L.N. and Lewy A.J.Editors: M.P. Szuba, J.D. Kloss and D.F. Dinges.Cambridge University Press, New York, NY2003
• Hormonal Modulation of Brain and Behavior 
  Chapter: Melatonin modulation of brain and behavior: clinical aspects 
  Lewy A.J., Hughes R.J., Bauer V.K., Cutler N.L. and Sack R.L.Editors: U. Halbreich.American Psychiatric Press, Washington, DC2003
• Neuropsychopharmacology: The Fifth Generation of Progress 
  Chapter: Circadian phase sleep and mood disorders 
  Lewy A.J. and Sack R.L.Editors: Charney D., Coyle J., Davis K., Nemeroff C.Lippincott Williams & Wilkins, Baltimore, MD2002
• Sleep Medicine 
  Chapter: Jet lag and shift work 
  Page 255 - 263Sack, R.L.Editors: Lee-Chiong, TL, Sateia, MJ and Carskadon, MA.Hanley and Belfus, Philadelphia, PA2002
• Melatonin in Psychiatric and Neoplastic Disorders 
  Chapter: Melatonin in circadian phase sleep and mood disorders 
  Page 81 - 104Lewy A.J., Sack R.L., Cutler N.L., Bauer V.K. and Hughes R.J.Editors: M. Shafii and S.L. Shafii.American Psychiatric Press, Washington, DC1998
• Biological Clocks: Mechanisms and Applications 
  Chapter: The use of light and melatonin in the treatment of circadian phase disorders 
  Page 259 - 264Lewy A.J., Cutler N.L. and Sack R.L.Editors: Y. Touitou.Elsevier, Amsterdam, The Neatherlands1998
• Progress in Brain Research Vol. 111, Hypothalamic Integration of Circadian Rhythms 
  Chapter: The role of melatonin and light in the human circadian system 
  Page 205 - 215Lewy A.J. and Sack R.L.Editors: R.M. Buijs, A. Kalsbeek, H.J. Romijn, C.M.A. Pennartz and M. Mirmiran.Elsevier, Amsterdam, The Neatherlands1996
• The Pineal Gland and Its Hormones: Fundamental and Clinical Perspectives 
  Chapter: The influence of melatonin on the human circadian clock 
  Page 173 - 182Lewy A.J., Sack R.L., Ahmed S., Bauer V.K., and Blood M.L.Editors: F. Fraschini, R.J. Reiter and B. Stankov.Plenum Press, New York, NY1995
• Evolution of the Circadian Clock 
  Chapter: Melatonin and evolution 
  Page 291 - 310Lewy A.J., Sack R.L., Singer C.M., and Ahmed S.Editors: T. Hiroshige and K. Honma.1995
• Circadian Clocks and Their Adjustment 
  Chapter: Melatonin marks circadian phase position and resets the endogenous circadian pacemaker in humans 
  Page 303 - 321Lewy A.J., Sack R.L., Blood M.L., Bauer V.K., Cutler N.L., and Thomas K.H.Editors: D.J. Chadwick and K. Ackrill.John Wiley, New York, NY1994
• Advances in Pineal Research: 5 
  Chapter: Melatonin and the acute suppressant effect of light may help regulate circadian rhythms in humans 
  Page 285 - 293Lewy A.J., Sack R.L. and Latham J.MEditors: J. Arendt and P. Pevet.John Libbey, London, UK1991
• Biological Rhythms, Mood Disorders, Light Therapy, and the Pineal Gland 
  Chapter: Bright light, melatonin and winter depression: the phase-shift hypothesis 
  Page 143 - 173Lewy A.J., Sack R.L., Singer C.M.Editors: M.A. Shafii.American Psychiatric Press, Washington, DC1990
• Sleep and Biological Rhythms: Basic Mechanisms and Applications to Psychiatry 
  Chapter: Bright light, melatonin and biological rhythms in humans 
  Page 99 - 112Lewy A.J. and Sack R.L.Editors: J. Montplaisir and R. Godbout.Oxford University Press, New York, NY1990
• Seasonal Affective Disorders and Phototherapy 
  Chapter: Winter depression and the phase-shift hypothesis for bright light's therapeutic effects: History, theory and experimental evidence 
  Page 295 - 310Lewy A.J., Sack R.L., Singer C.M., White D.M. and Hoban T.M.Editors: N.E. Rosenthal, M.C. Blehar.Guilford Press, New York, NY1989
• Seasonal Affective Disorder 
  Chapter: Winter depression: the phase angle between sleep and other circadian rhythms may be critical 
  Page 205 - 221Lewy A.J., Sack R.L., Singer C.M., White D.M. and Hoban T.M.Editors: Winter depression: the phase angle between sleep and other circadian rhythms may be critical.Winter depression: the phase angle between sleep and other circadian rhythms may be critical, London, UK1989
• Biological Rhythms and Mental Disorders 
  Chapter: Intensity, wavelength and timing: three critical parameters for chronobiologically active light 
  Page 188 - 207Lewy A.J. and Sack R.L.Editors: D.J. Kupfer, T.H. Monk, and J.D. Barchas.Guilford Press, New York, NY1988
• Melatonin: Clinical Perspectives 
  Chapter: Melatonin and major affective disorder 
  Page 205 - 227Sack R.L. and Lewy A.J.Editors: A. Miles, D. Philbrick, C. Thompson.Oxford Medical Publications, New York, NY1988
• Treating Resistant Depression 
  Chapter: Bright light used to treat sleep and mood disorders 
  Page 321 - 341Lewy A.J. and Sack R.L.Editors: J. Zohar and R.H. Belmaker.PMA Publishing Corp., New York, NY1987
• Temporal Disorder in Human Oscillatory Systems 
  Chapter: Treatment of chronobiologic sleep and mood disorders with light: theory and practice 
  Page 210 - 218Lewy A.J. and Sack R.L.Editors: L. Rensing, U. an der Heiden, M.C. Mackey.Springer-Verlag, Heidelberg1987
• Temporal Disorder in Human Oscillatory Systems 
  Chapter: Free running melatonin rhythm in blind people: phase shifts with melatonin and triazolam administration 
  Page 219 - 224Sack R.L., Lewy A.J. and Hoban T.M.Editors: L. Rensing, U. an der Heiden, M.C. Mackey.Springer-Verlag, Heidelberg1987
• Biological Psychiatry 1985 
  Chapter: Three critical parameters for using light to treat psychiatric disorders 
  Page 984 - 986Lewy A.J., Sack R.L., Miller L.S., Hoban T.M. and Singer C.M.Editors: C. Shagass, R.C. Josiassen, W.H. Bridger, K.J. Weiss, D. Stoff, G.M. Sampson.Elsevier Science Publishing Company, New York, NY1986
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Abstracts/Posters

• Melatonin rhythms in permanent and rotating shift workers
  Sack R.L., Blood M.L., Rich G.B. and Lewy A.J., 6th Colloquium of the European Pineal Society, The Panum Institute, University of Copenhagen, 1/1/1993

Other

• Studies on the mechanism of action of lithium in man: A contribution to the neurobiological theories of affective illness 
  Studies on the mechanism of action of lithium in man: A contribution to the neurobiological theories of affective illness, Studies on the mechanism of action of lithium in man: A contribution to the neurobiological theorie
  1/1/1976
• The effect of peripheral stimulation on the protein metabolism of the cat cortex 
  Sack, R.L., University of Oregon Medical School Library
  1/1/1968