
Robert M Samstein MD PhD
Thoracic Cancer
Associate Professor, Precision Immunology Institute and Radiation Oncology
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1470 Madison AveNew York, NY 10029
Phone+1 646-605-5845
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Summary
- Robert Samstein, MD, is a Radiation Oncologist and Immunologist based in New York, NY, specializing in thoracic cancer, with a focus on lung cancer, lung nodules, and small cell lung cancer. He completed his residency in Radiation Oncology at Memorial Sloan Kettering Cancer Center in 2019, following his graduation from Weill Cornell Medicine in 2014. Since 2019, he has been serving on faculty at the Icahn School of Medicine at Mount Sinai. His research publications cover a range of topics, including the immune microenvironment and response to immunotherapy, optimization strategies in lung cancer treatment planning, and the immune system's contribution to early cancer development and prevention.
Education & Training
Memorial Sloan Kettering Cancer CenterResidency, Radiation Oncology, 2015 - 2019
Weill Cornell MedicineClass of 2014
Certifications & Licensure
NY State Medical License 2015 - 2028
American Board of Radiology Radiation Oncology
Publications & Presentations
PubMed
- Lung Cancer in Never Smokers: Genetics, Epidemiology, Environmental Exposures, and Distinct Immune Landscape.Jiahua Lu, Elaine Shum, Robert M Samstein, Diddier Prada, Fred R Hirsch
Journal of Thoracic Oncology. 2026-07-01 - Reprogramming T cell-myeloid crosstalk overcomes immune resistance in colorectal cancer.Guillaume Mestrallet, Matthew Brown, Natalie Vaninov, Nam Woo Cho, Leandra Velazquez
Cell Reports. Medicine. 2026-05-19 - Mismatch repair deficiency drives malignant progression and alters the tumor immune microenvironment in glioblastoma models.Montserrat Puigdelloses Vallcorba, Nishant Soni, Seung-Won Choi, Kavita Rawat, Tanvi Joshi
The Journal of Clinical Investigation. 2026-03-16
Press Mentions
Plenary Session SummaryOctober 8th, 2024
Taking CAR T Cells up a Synthetic NotchFebruary 10th, 2021
After Recovering from COVID-19, Are You Immune?May 14th, 2020
Grant Support
- Immune determinants modulating cancer development in Lynch SyndromeICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2024–2029
- Immunogenetic determinants of cancer riskICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2024–2029
- Spatial functional genomics to identify regulators of the tumor microenvironment and cancer immunityICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2023–2028
- Spatial functional genomics to identify regulators of the tumor microenvironment and cancer immunityICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2023–2028
- Spatial functional genomics to identify regulators of the tumor microenvironment and cancer immunityICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2023–2028
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