RobertTStrikerMD

PubMed

• 4 citations
  A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility.
  Georgios Voloudakis, James M Vicari, Sanan Venkatesh, Gabriel E Hoffman, Kristina Dobrindt, Wen Zhang, Noam D Beckmann, Christina A Higgins, Stathis Argyriou, Shan Jia...> ;NPJ Genomic Medicine. 2022 Sep 5
• 10 citations
  IL10RB as a key regulator of COVID-19 host susceptibility and severity
  Georgios Voloudakis, Gabriel E. Hoffman, Sanan Venkatesh, Kyung Min Lee, Kristina Dobrindt, James M. Vicari, Wen Zhang, Noam D. Beckmann, Shan Jiang, Daisy A. Hoagland...> ;Medrxiv. 2021 Jun 2
• 7 citations
  Immune recovery in HIV-1 infected patients with sustained viral suppression under long-term antiretroviral therapy in Ethiopia.
  Dawit Wolday, Dorsisa Legesse, Yazezew Kebede, Dawd Siraj, Joseph A. McBride, Rob Striker> ;Plos One. 2020 Oct 22
• 12 citations
  Role of CD4/CD8 ratio on the incidence of tuberculosis in HIV-infected patients on antiretroviral therapy followed up for more than a decade.
  Dawit Wolday, Yazezew Kebede, Dorsisa Legesse, Dawd Siraj, Joseph A. McBride, Mitchell J. Kirsch, Rob Striker> ;Plos One. 2020 May 22
• 23 citations
  GW779439X and Its Pyrazolopyridazine Derivatives Inhibit the Serine/Threonine Kinase Stk1 and Act As Antibiotic Adjuvants against β-Lactam-Resistant Staphylococcus aur...
  Adam J. Schaenzer, Nathan Wlodarchak, David H. Drewry, William J. Zuercher, Warren E. Rose, Carla Alamillo Ferrer, John-Demian Sauer, Rob Striker> ;ACS Infectious Diseases. 2018 Aug 15
• 152 citations
  Imbalance in the game of T cells: What can the CD4/CD8 T-cell ratio tell us about HIV and health?
  Joseph A. McBride, Rob Striker> ;Plos Pathogens. 2017 Nov 2
• 9 citations
  Transmission of Donor-Derived Trypanosoma cruzi and Subsequent Development of Chagas Disease in a Lung Transplant Recipient
  A B Corey, D Sonetti, James D. Maloney, Susan P. Montgomery, B L Rademacher, Lauren J. Taylor, J A Smith, Rob Striker> ;Case Reports in Infectious Diseases. 2017 Aug 21
• 3 citations
  Human immunodeficiency virus testing pitfalls and clinical suspicion.
  Kazuaki Jindai, Bethaney Kunzer, Tam T. Van, Rob Striker> ;The American Journal of Emergency Medicine. 2014 Nov 1
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Abstracts/Posters

• Vitamin D and the Antiviral State.
  Beard, J. Beardon, A and Striker R, Journal of Clinical Virology, J Clinical Virology 50(3):194-200
• Naturally Occurring Genotype 2b/1a Hepatitis C Virus in the United States
  Dipankar Bhattacharya, Molly A Accola, Israr H Ansari, Rob Striker and William M Rehrauer, Virol J 3;8:458
• A thiopurine drug inhibits West Nile virus production in cell culture, but not in mice.
  Lim PY, Keating JA, Hoover S, Striker R, Bernard KA, PLoS One, e26697. PMID: 22039536
• Treatment of Hepatitis C Virus Infection among Incarcerated Adults.
  Rice J., Burnett, D., Tsotsis A Helena; Lindstrom Mary J; Striker R. Lucey, Michael R, Hepatology
• Analysis of Hepatitis C Virus Intra- Host Diversity Across The Coding Region by Ultra-Deep Pyrosequencing.
  M. Lauck, M.V. Alvarado-Mora, E. A. Becker, D. Bhattacharya, R. Striker, A. L. Hughes, F. J. Carrilho, D. H. O’Connor, J. R. Rebello Pinho, Journal of Virology, 86(7):3952-60. PMID: 22278255
• Phosphorylation events during viral infections provide potential therapeutic targets.
  Keating JA and Striker, R, Rev Med Virol, PMID: 22113983
• FRET based Intracellular Assay for the conformation of Hepatitis C drug target NS5A Dipankar Bhattacharya
  Israr-ul Ansari, Andrew Mehle, R Striker, Journal of Virology, J Virol, 86(15):8277-86
• Insect Kinase phosphorylates arboviruses and controls flight.
  JA Keating JA and Striker, R, Journal of Vector Borne and Zoonotic
• Addition of Ceftaroline to Daptomycin after Emergence of Daptomycin-Nonsusceptible Staphylococcus Aureus during therapy improves Antibacterial Activity.
  Rose WE, Schulz LT, Andes D, Striker R, Berti AD, Hutson PR, Shukla SK, Antimicrob Agents Chemother, 56(10):5296-302
• vitro studies on the stability and disassembly of P Pili.
  Striker, R., and Hultgren, S.J, FEMS Symposium, Helsinki, Finland
• Stable fiber-forming and non-fiber-forming chaperone-subunit complexes in Pilus biogenesis.
  Striker, R., Jacob-Dubuisson, F., Frieden, C., and Hultgren, S.J, ASBMB/DBC-ACS Meeting, San Diego, CA
• Effect of immunosuppressants on a model virus for hepatitis C virus.
  Stangl, J. et al and Striker, R, AASLD-HCV conference, Chicago, IL
• 9th Symposium on positive strand viruses.
  Striker, R. and Hoover, SW, Novel thiopurine antiviral prodrug, San Franciso
• Cyclosporine Effects on HCV Replicase.
  Striker, R. and Fiona Fernandes, ASV Madison, WI
• Cyclosporine susceptibility is determined by HCV NS5A and NS5B.
  Striker, R. and Fiona Fernandes, AASLD, Boston
• Tailoring Immunosuppressants for Hepatitis C Virus Infected Patients.
  Striker, R. Spencer Hoover and Fiona Fernandes, ASCI/AAP Joint Meeting, Chicago
• 10th Symposium on positive Strand viruses.
  Striker, R. and Fiona Fernandes, Cyclosporine Selection of HCV, Washington DC
• Resistance of HCV to cyclophilin inhibitors.
  Fiona Fernandes, J. Gerstner, and R Striker, ASV, Cornell, NY
• Phosphorylation of Flaviviruses.
  R Striker, S Hoover, and D Bhattacharya, ASV, Cornell, NY
• Evidence for two divergent clades of genotype 1a HCV that have spread across the world.
  Pickett, B. Striker, R., Lefkowitz, E, 15th International Symposium on HCV, San Antonio Texas
• Evidence for separation of genotype 1a into two distinct clades.
  Pickett, B. Striker, R., Lefkowitz, E, Journal of Viral Hepatitis, J Viral Hepat
• Cyclosporine inhibits a direct interaction between Hepatitis C Virus NS5A and Cyclophilins.
  Fernandes, FJ, Ansari, I. and Striker, R, PLOS One, San Francisco, CA
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Lectures

• Hepatitis C Viral Polymerase, University of Colorado 
• Hepatitis C Viral Polymerase, University of Wisconsin-Madison Infectious diseases section. 
• Hepatitis C Viral Polymerase, 
  Pharmmasset Inc.
• Hepatitis C Viral Polymerase. 
  Emory University
• Hepatitis C Viral Polymerase. 
  University of Wisconsin-Madison MedicalScientist Training Program
• Modeling Hepatitis C Virus in Cell Culture. 
  UW-Madison Hepatology and Gastroenterology Section
• Tailoring Immunosuppressants for HCV infected transplant patients. 
  Department of Surgery
• Immunosuppressants as Antivirals for Hepatitis C Virus. 
  UW-Madison, Department of Pathology and Laboratory Medicine
• Understanding Flaviviral Genetics for Drug Susceptibility. 
  Purdue University
• Understanding Flaviviral Genetics for Drug Susceptibility. 
  University of Alabama-Birmingham
• Understanding Flaviviral Genetics for Drug Susceptibility. 
  Medical College of Wisconsin
• Genetics of Hepatitis C NS5A drug susceptibility. 
  Bristol-Meyers -Squibb
• How arbovirus’s manipulate mosquito behavior. 
  Notre Dame by the Eck Institute for Global Health.
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Other

• Nucleoside Analogues for the Treatment or Prevention of Flaviviridae Infections. 
  R. Striker, and R.F. Schinazi
• cis-6-(2-ACETYLVINYLTHIO) PURINE AS AN ANTIVIRAL AGENT. 
  R. Striker, S. Gunnarsdottir, and A. Elffarra
• Cyclosporine resistance mutations in Hepatitis C Virus. 
  R.Striker and D. Poole
• Degradation of gonococcal peptidoglycan extract from human neutrophils: demonstration of N-acetylglucosaminidase activity that utilizes peptidoglycan substrates. 
  1. Striker R., Kline, M.E., Haak, R., Rest, R., and Rosenthal, R.S
• Adhesin presentation in bacteria requires molecular chaperones and ushers. 
  2. Jones, C.H., Jacob-Dubuisson, F., Dodson K., Kuehn, M., Slonim, L., Striker, R., and Hultgren, S.J
• Assembly of adhesive virulence associated Pili in gram-negative bacteria. Escherichia coli: Mechanisms of Virulence. Ed. Max Sussman. 
  3. Dodson, K.W., Jacob-Dubuisson, F., Striker, R., and Hultgren, S.J
• Outer membrane PapC usher discriminately recognizes periplasmic chaperone-pilus subunit complexes. 
  4. Dodson, K.W., Jacob-Dubuisson, F., Striker, R.T., and Hultgren, S.J
• The role of DsbA in chaperone mediated Pilus assembly. 
  5. Jacob-Dubuisson, Xu, Z., Pinkner, J., Striker, R., and Hultgren, S.J
• Chaperone-assisted self-assembly of Pili independent of cellular energy. 
  The role of DsbA in chaperone mediated Pilus assembly
• Genetic, biochemical, and structural studies on the biogenesis of adhesive Pili in bacteria. 
  7. Kuehn, M., Jacob-Dubuisson, F., Dodson K., Slonim, L., Striker, R., and Hultgren, S.J
• Stable fiber-forming and nonfiber-forming chaperone-subunit complexes in Pilus biogenesis. 
  8. Striker, R., Jacob-Dubuisson, F., Frieden, C., and Hultgren, S.J
• Structural requirements for the glycolipid receptor of human uropathogenic. 
  Striker, R., Nilson, U., Stoncipher, A., Magnussen, G., and Hultgren, S.J
• Structural constraints of the carbohydrate binding surface of PapG adhesin of Pili and preassembly complex. 
  Nilson, U., Striker, R., Hultgren, S.J., Magnussen, G
• Development of pilus organelle subassemblies in vitro depends on chaperone uncapping of a beta zipper. 
  Striker, R., Bullit, E., Jones, C.H., Soto, G., Jacob-Dubuisson, F., Pinkner, J., Wick, M.J., Makowski, L., Hultgren, S.J
• Localized adipose hypertrophy in patients on protease inhibitor therapy. 
  Striker, R., Conlin, D., Marx, M., Wiviott, L
• Effect of antimetabolite immunosuppressants on Flaviviridae including Hepatitis C Virus. 
  Stangl, J., Carroll, K., Illichmann, M. and Striker, R.
• Parapox infection complicated by erythema multiforme and graft versus host disease after allogeneic hematopoietic stem cell transplantation for multiple myeloma. 
  Slattery, W., Juckett, M., Agger, B., Radi, C., Mitchell, T. and Striker, R
• Clearance duration as predictor of sustained response to interferon/ribavirin in HCV. 
  Shenoi, M., Said, A., Levin, J. and Striker, R
• Cyclosporine sensitivity of Hepatitis C Virus depends upon both NS5A and NS5B sequence variations Hepatology. 
  Fernandes, F., Poole, D.S. Gerstner, J., Middleton, R., Andrei, A., Hoover, S., and Striker, R
• Lipid Transfection of recombinant Viral RNAs. 
  Gonzales, G., Pfannes, L., Brazas, R. and Striker, R
  Journal of Virological Methods
• Thiopurines inhibit bovine viral diarrhea Virus in a thiopurine methyl transferase-dependant manner. 
  Hoover, S. and R. Striker
  Journal of Gen Virology
• Flaviviral NS5 Phosphorylation can regulate viral methyl transferase activity. 
  Bhattacharya, D. Spencer Hoover, Shawn White, Martha Viestling, Bernard Weisblum and R. Striker
• The flaviviral methyltransferase is a substrate of Casein Kinase 1. Virus Res. 
  Bhattacharya, D. and R. Striker
• Protein Kinase G phosphorylates mosquito borne flaviviruses. Journal of Virology 
  Bhattacharya, D. Mayuri, Kuhn, R., and R. Striker
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