RobertaAWilliamsonMD

PubMed

• A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus.
  Schuster JE, Cox RG, Hastings AK, Boyd KL, Wadia J, Chen Z, Burton DR, Williamson RA, Williams JV> ;J. Infect. Dis.. 2015-01-15
• Lack of prion infectivity in fixed heart tissue from patients with Creutzfeldt-Jakob disease or amyloid heart disease.
  Priola SA, Ward AE, McCall SA, Trifilo M, Choi YP, Solforosi L, Williamson RA, Cruite JT, Oldstone MBA> ;J. Virol.. 2013-09-01
• 146 citations
  Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid
  Gregory P. Owens, Jeffrey Bennett, Hans Lassmann, Kevin C. O’Connor, Alanna M. Ritchie, Andrew J. Shearer, Chiwah Lam, Xiaoli Yu, Marius Birlea, Cecily Dupree, R. Anth...> ;Annals of Neurology. 2009 Jun 1
• Identifying key components of the PrPC-PrPSc replicative interface.
  Abalos GC, Cruite JT, Bellon A, Hemmers S, Akagi J, Mastrianni JA, Williamson RA, Solforosi L> ;J. Biol. Chem.. 2008-12-05
• Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.
  Biasini E, Seegulam ME, Patti BN, Solforosi L, Medrano AZ, Christensen HM, Senatore A, Chiesa R, Williamson RA, Harris DA> ;J. Neurochem.. 2008-06-01
• Selective incorporation of polyanionic molecules into hamster prions.
  Geoghegan JC, Valdes PA, Orem NR, Deleault NR, Williamson RA, Harris BT, Supattapone S> ;J. Biol. Chem.. 2007-12-14
• Toward molecular dissection of PrPC-PrPSc interactions.
  Solforosi L, Bellon A, Schaller M, Cruite JT, Abalos GC, Williamson RA> ;J. Biol. Chem.. 2007-03-09
• Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions.
  Deleault NR, Geoghegan JC, Nishina K, Kascsak R, Williamson RA, Supattapone S> ;J. Biol. Chem.. 2005-07-22
• Comparative analysis of the CD19+ and CD138+ cell antibody repertoires in the cerebrospinal fluid of patients with multiple sclerosis.
  Ritchie AM, Gilden DH, Williamson RA, Burgoon MP, Yu X, Helm K, Corboy JR, Owens GP> ;J. Immunol.. 2004-07-01
• Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation.
  Yadavalli R, Guttmann RP, Seward T, Centers AP, Williamson RA, Telling GC> ;J. Biol. Chem.. 2004-05-21
• Cross-linking cellular prion protein triggers neuronal apoptosis in vivo.
  Solforosi L, Criado JR, McGavern DB, Wirz S, Sánchez-Alavez M, Sugama S, DeGiorgio LA, Volpe BT, Wiseman E, Abalos G, Masliah E, Gilden D, Oldstone MB, Conti B, Willia...> ;Science. 2004-03-05
• Single-cell repertoire analysis demonstrates that clonal expansion is a prominent feature of the B cell response in multiple sclerosis cerebrospinal fluid.
  Owens GP, Ritchie AM, Burgoon MP, Williamson RA, Corboy JR, Gilden DH> ;J. Immunol.. 2003-09-01
• Trafficking of prion proteins through a caveolae-mediated endosomal pathway.
  Peters PJ, Mironov A, Peretz D, van Donselaar E, Leclerc E, Erpel S, DeArmond SJ, Burton DR, Williamson RA, Vey M, Prusiner SB> ;J. Cell Biol.. 2003-08-18
• Conformation of PrP(C) on the cell surface as probed by antibodies.
  Leclerc E, Peretz D, Ball H, Solforosi L, Legname G, Safar J, Serban A, Prusiner SB, Burton DR, Williamson RA> ;J. Mol. Biol.. 2003-02-14
• Characteristics of immunity induced by viral antigen or conferred by antibody via different administration routes.
  Matsuoka T, Okamoto Y, Matsuzaki Z, Endo S, Ito E, Tsutsumi H, Williamson RA, Sakurai H, Burton DR, Saito I> ;Clin. Exp. Immunol.. 2002-12-01
• Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice.
  Safar JG, Scott M, Monaghan J, Deering C, Didorenko S, Vergara J, Ball H, Legname G, Leclerc E, Solforosi L, Serban H, Groth D, Burton DR, Prusiner SB, Williamson RA> ;Nat. Biotechnol.. 2002-11-01
• Neutralizing human Fab fragments against measles virus recovered by phage display.
  de Carvalho Nicacio C, Williamson RA, Parren PWHI, Lundkvist A, Burton DR, Björling E> ;J. Virol.. 2002-01-01
• Tyrosine 36 plays a critical role in the interaction of the AB loop of tissue inhibitor of metalloproteinases-2 with matrix metalloproteinase-14.
  Williamson RA, Hutton M, Vogt G, Rapti M, Knäuper V, Carr MD, Murphy G> ;J. Biol. Chem.. 2001-08-31
• Antibodies inhibit prion propagation and clear cell cultures of prion infectivity.
  Peretz D, Williamson RA, Kaneko K, Vergara J, Leclerc E, Schmitt-Ulms G, Mehlhorn IR, Legname G, Wormald MR, Rudd PM, Dwek RA, Burton DR, Prusiner SB> ;Nature. 2001-08-16
• Sequence-specific assignment and determination of the secondary structure of the 163-residue M. tuberculosis and M. bovis antigenic protein mpb70.
  Bloemink MJ, Kemmink J, Dentten E, Muskett FW, Whelan A, Sheikh A, Hewinson G, Williamson RA, Carr MD> ;J. Biomol. NMR. 2001-06-01
• Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form.
  Leclerc E, Peretz D, Ball H, Sakurai H, Legname G, Serban A, Prusiner SB, Burton DR, Williamson RA> ;EMBO J.. 2001-04-02
• Molecular profile of a human monoclonal antibody Fab fragment specific for Epstein-Barr virus gp350/220 antigen.
  Bugli F, Bastidas R, Burton DR, Williamson RA, Clementi M, Burioni R> ;Hum. Immunol.. 2001-04-01
• Strain-specified relative conformational stability of the scrapie prion protein.
  Peretz D, Scott MR, Groth D, Williamson RA, Burton DR, Cohen FE, Prusiner SB> ;Protein Sci.. 2001-04-01
• Anti-DNA antibodies are a major component of the intrathecal B cell response in multiple sclerosis.
  Williamson RA, Burgoon MP, Owens GP, Ghausi O, Leclerc E, Firme L, Carlson S, Corboy J, Parren PW, Sanna PP, Gilden DH, Burton DR> ;Proc. Natl. Acad. Sci. U.S.A.. 2001-02-13
• Molecular immunologic strategies to identify antigens and b-cell responses unique to multiple sclerosis.
  Gilden DH, Burgoon MP, Kleinschmidt-DeMasters BK, Williamson RA, Ghausi O, Burton DR, Owens GP> ;Arch. Neurol.. 2001-01-01
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