Roger J Laham MD

PubMed

• Practice Patterns and Outcomes for Tricuspid Interventions Among Medicare Patients With Cardiac Implantable Electronic Devices.
  Enrico G Ferro, Lorenzo V Arvanitis, Siling Li, Yang Song, Roger J Laham
  JACC. Clinical Electrophysiology. 2025-11-02
• Uptake, Geographic Access, and Outcomes of Transcatheter Mitral Valve Repair in the United States.
  Atsuyuki Watanabe, Hiroki A Ueyama, Yoshihisa Miyamoto, Hiroshi Gotanda, Tsuyoshi Kaneko
  Circulation. Cardiovascular Quality and Outcomes. 2025-10-31
• Comparison of Limus and Paclitaxel Drug-Coated Balloons, Second-Generation or Newer Drug-Eluting Stents, and Balloon Angioplasty: A Network Meta-Analysis of Randomized...
  Yuko Kiyohara, Tadao Aikawa, Tetsuya Saito, Abel Casso Dominguez, Jose Wiley
  Circulation. Cardiovascular Interventions. 2025-10-27

Journal Articles

• Frailty Phenotype and Deficit Accumulation Frailty Index in Predicting Recovery After Transcatheter and Surgical Aortic Valve Replacement  
  Roger J Laham, Jeffrey J Popma, Kamal R Khabbaz, The Journals of Gerontology
• Patterns of coronary arterial lesion calcification by a novel, cross-sectional CT angiographic assessment  
  Cerci R, Vavere AL, Miller JM, Yoneyama K, Rochitte CE, Dewey M, Niinuma H, Clouse ME, Laham R, Bush DE, Shapiro EP, Lardo AC, Cox C, Brinker J, Lima JA, Arbab-Zadeh A, Int J Cardiovasc Imaging, 10/1/2013
• Ethanol promotes arteriogenesis and restores perfusion to chronically ischemic myocardium  
  Lassaletta AD, Elmadhun NY, Liu Y, Feng J, Burgess TA, Karlson NW, Laham RJ, Sellke FW, Circulation, 9/10/2013
• Resveratrol preserves myocardial function and perfusion in remote nonischemic myocardium in a swine model of metabolic syndrome  
  Robich MP, Chu LM, Burgess TA, Feng J, Han Y, Nezafat R, Leber MP, Laham RJ, Manning WJ, Sellke FW, J Am Coll Surg, 11/1/2012
• Effects of red wine and vodka on collateral-dependent perfusion and cardiovascular function in hypercholesterolemic swine  
  Chu LM, Lassaletta AD, Robich MP, Liu Y, Burgess T, Laham RJ, Sweeney JD, Shen TL, Sellke FW, Circulation, 9/1/2012
• Percutaneous retrieval of fractured bird's nest ivc filter penetrating into aorta  
  Touchan J, Levy MS, Laham RJ, Catheter Cardiovasc Interv, 1/1/2012
• Overfed ossabaw swine with early stage metabolic syndrome have normal coronary collateral development in response to chronic ischemia  
  Lassaletta AD, Chu LM, Robich MP, Elmadhun NY, Feng J, Burgess TA, Laham RJ, Sturek M, Sellke FW, Basic Res Cardiol, 1/1/2012
• Paclitaxel/sirolimus combination coated drug-eluting stent: In vitro and in vivo drug release studies  
  Ma X, Oyamada S, Gao F, Wu T, Robich MP, Wu H, Wang X, Buchholz B, McCarthy S, Gu Z, Bianchi CF, Sellke FW, Laham R, J Pharm Biomed Anal, 1/1/2011
• Autologous cardiomyotissue implantation promotes myocardial regeneration, decreases infarct size, and improves left ventricular function  
  Wykrzykowska JJ, Rosinberg A, Lee SU, Voisine P, Wu G, Appelbaum E, Boodhwani M, Sellke FW, Laham RJ, Circulation, 1/1/2011
• Trans-iliac rat aorta stenting: A novel high throughput preclinical stent model for restenosis and thrombosis  
  Oyamada S, Ma X, Wu T, Robich MP, Wu H, Wang X, Buchholz B, McCarthy S, Bianchi CF, Sellke FW, Laham R, J Surg Res, 1/1/2011
• In vitro and in vivo degradation of poly(d, l-lactide-co-glycolide)/amorphous calcium phosphate copolymer coated on metal stents  
  Ma X, Oyamada S, Wu T, Robich MP, Wu H, Wang X, Buchholz B, McCarthy S, Bianchi CF, Sellke FW, Laham R, J Biomed Mater Res A, 1/1/2011
• Repeated successful balloon valvuloplasty of a bioprosthetic aortic valve in a nonagenerian  
  Dejam A, Hokinson M, Laham R, Catheter Cardiovasc Interv, 1/1/2011
• Resveratrol supplementation abrogates pro-arteriogenic effects of intramyocardial vascular endothelial growth factor in a hypercholesterolemic swine model of chronic i...  
  Chu LM, Robich MP, Lassaletta AD, Feng J, Laham RJ, Burgess T, Clements RT, Sellke FW, Surgery, 1/1/2011
• Distal anchoring technique: Yet another weapon for successful intervention  
  Pervaiz MH, Laham RJ, J Invasive Cardiol, 1/1/2011
• Virtual histologic guidance of percutaneous peripheral atherectomy: The evolution of a new paradigm?  
  Levy MS, Laham RJ, J Invasive Cardiol, 1/1/2011
• Intracardiac Echocardiography and fluoroscopy Guided Percutaneous Left Ventricular Pseudoaneurysm closure  
  Melman J, Levy MS, Laham RJ, Catheter Cardiovasc Interv, 1/1/2011
• Diagnostic performance of combined noninvasive coronary angiography and myocardial perfusion imaging using 320 row detector computed tomography: Design and implementat...  
  Vavere AL, Simon GG, George RT, Rochitte CE, Arai AE, Miller JM, Di Carli M, Zadeh AA, Dewey M, Niinuma H, Laham R, Rybicki FJ, Schuijf JD, Paul N, Hoe J, Kuribyashi S..., J Cardiovasc Comput Tomogr, 1/1/2011
• Anti-angiogenic effect of high-dose resveratrol in a swine model of metabolic syndrome  
  Robich MP, Chu LM, Chaudray M, Nezafat R, Han Y, Clements RT, Laham RJ, Manning WJ, Coady MA, Sellke FW, Surgery, 1/1/2010
• Effects of Neuropeptide Y on collateral development in a swine model of chronic myocardial ischemia  
  Robich MP, Matyal R, Chu LM, Feng J, Xu SH, Laham RJ, Hess PE, Bianchi C, Sellke FW, J Mol Cell Cardiol, 1/1/2010
• Effects of selective cyclooxygenase-2 and nonselective cyclooxygenase inhibition on ischemic myocardium  
  Robich MP, Chu LM, Feng J, Burgess TA, Laham RJ, Bianchi C, Sellke FW, J Thorac Cardiovasc Surg, 1/1/2010
• Temporal and Spatial Changes in Collateral Formation and Function During Chronic Myocardial Ischemia  
  Robich MP, Osipov RM, Chu LM, Feng J, Burgess TA, Oyamada S, Clements RT, Laham RJ, Sellke FW, J Am Coll Surg, 1/1/2010
• Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia  
  Robich MP, Osipov RM, Nezafat R, Feng J, Clements RT, Bianchi C, Boodhwani M, Coady MA, Laham RJ, Sellke FW, Circulation, 1/1/2010
• Endostatin and angiostatin are increased in diabetic patients with coronary artery disease and associated with impaired coronary collateral formation  
  Sodha NR, Clements RT, Boodhwani M, Xu SH, Laham RJ, Bianchi C, Sellke FW, Am J Physiol Heart Circ Physiol, 1/1/2009
• Exercise-Induced Expression of VEGF and Salvation of Myocardium in the Early Stage of Myocardial Infarction  
  Exercise-Induced Expression of VEGF and Salvation of Myocardium in the Early Stage of Myocardial Infarction, Am J Physiol Heart Circ Physiol, 1/1/2009
• Imaging of Inflammatory/Vulnerable plaque in coronary arteries with 18FDG PET/CT in patients with suppression of myocardial uptake using a low carbohydrate, high fat p...  
  Wykrzykowska JJ, Lehman S, Williams G, Parker JA, Palmer M, Varkey SC, Kolodny G, Laham RJ, J Nuclear Medicine, 1/1/2009
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Books/Book Chapters

• Angiogenesis and DMR 
  Editors: Roger Laham and Donald Baim.Humana Press2005
• Angiogenesis and Cardiovascular Disease 
  Chapter: Therapeutic angiogenesis in myocardial ischemia 
  Page 289 - 320Simons, M, Laham RJEditors: Simons and Ware.Oxford University press1999
• Handbook of myocardial Revascularization and Angiogenesis 
  Chapter: Basic Fibroblast Growth Factor Protein for Coronary Artery Disease 
  Page 175 - 187Laham RJ, Simons MMartin Dunitz Ltd1999
• Intensive Care Medicine 
  Chapter: Acute heart failure in Intensive Care Medicine 
  Caputo R, Laham RJEditors: Rippe JM, Irwin RS, Fink MP, Cerra FB.Little, Brown Co., BostonEdition 3rd,1996
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Abstracts/Posters

• Exercise-Induced Expression of Angiogenic Cytokines in Normal and Infarcted Hearts
  Wu G, Rana J, Wykrzykowska J, Kang P, Li J, Gibson CM, Sellke FW, Laham RJ, Circulation, 1/1/2005
• Atorvastatin Impairs Myocardial Angiogenic Response to Chronic Ischemia in Normocholesterolemic Swine
  Boodhwani M, Voisine P, Feng J, Xu S, Li J, Mieno S, Ramlawi B, Bianchi C, Laham RJ, Sellke F, Circulation, 1/1/2005
• Myotissue Implants Into Myocardial Infarct Zone Decreases Infarct Size and Improves Left Ventricular Function in Infarct Scar with Increased Cardiac Stem Cells
  Wykrzykowska J, Lee S, Mieno S, Appelbaum E, Donnell-Fink L, Boodhwani M, Li J, Sellke F, Gibson CM, Carrozza JP, Laham RJ, Circulation, 1/1/2005
• RTEF-1, A Novel Transcriptional Stimulator, Regulates FGF Receptor 1 Expression in Hypoxic Endothelial Cells
  Shie JL, Luo J, Laham RJ, Sellke F, Li J, Circulation, 1/1/2005
• Autologous Myotissue Transplantation in a Porcine Myocardial Infarction Model Results in Improved Function and Decreased Infarct Size
  Rosinberg A, Voisine P, Wu G, Applebaum G, Yeon S, Lee Seung, Carrozza JP, Sellke FW, Laham RJ, Journal of the American College of Cardiology, 1/1/2005
• Wu G, Rana J, Rosinberg A, Li J, Selke F, Laham RJ, Circulation, 1/1/2004
• Involvement of COX-2 in VEGF-induced Angiogenesis via P38 and JNK Pathway in Endothelial Cells
  Wu G, Rana J, Laham RJ, Sellke FW, Li J, Circulation, 1/1/2004
• Skin-Derived Micro-Tissue Autotransplantation as a Novel Approach for Therapeutic Angiogenesis
  Voisine P, Rosinberg A, Shamis Y, Wu G, Yeon S, Applebaum E, Mitrani E, Donnel-Fink L, Sellke FW, Laham RJ, Circulation, 1/1/2004
• Pattern of Brachytherapy Failure in Unselected Patients Treated With Gamma and Beta Radiation for Saphenous Vein Graft In-Stent Restenosis
  Bridges J, Pinto D, Pickett C, Ho K, Cutlip D, Laham RJ, Cohen DJ, Carrozza JP, Journal of the American College of Cardiology, 1/1/2004
• Chronic Hypercholesterolemia Induces Resistance to the Exogenous Effects of FGF-2 on Endothelial Function in a Swine Model of Chronic Myocardial Ischemia
  Voisine P, Ruel M, Bianchi C, Khan T, Xu Shu, Feng J, Li J, Laham RJ, Sellke FW, Circulation, 1/1/2003
• Expression of a Platelet-Derived Growth Factor (PDGF)-Signaling Pathway in a Porcine Model of Arterio-Venous (AV) Graft Stenosis
  Voisine P, Yadlapalli N, Khan TA, Laham RJ, Roy-Chaudhury P, Burnett SK, Bianchi C, Sellke FW, Sukhatme VP, Can J Cardiol, 1/1/2003
• Hypercholesterolemia-Induced Resistance to Exogenous FGF-2 Effects on Endothelial Function in a Swine Model of Chronic Myocardial Ischemia
  Voisine P, Ruel M, Bianchi C, Khan TA, Xu S, Feng J, Laham RJ, Sellke FW, Can J Cardiol, 1/1/2003
• Inhibited Angiogenic Response to Surgical FGF-2 Protein Therapy in a Swine Model of Endothelial Dysfunction
  Ruel M, Khan T, Laham R, Sellke FW, Circulation, 1/1/2002
• A Rest Bolus-Transit MRI Examination with Space-Time Maps Showing Delayed Equitime Is Comparable to Stress TC-99m-Sestamibi for Identifying Myocardium at Risk
  Gao L, Laham R, Post M, Simons M, Pearlman J, Parker A, Circulation, 1/1/2002
• Longevity of the Placebo Effect in Patients Enrolled in Angiogenesis and Laser Myocardial Revascularization Trials
  Longevity of the Placebo Effect in Patients Enrolled in Angiogenesis and Laser Myocardial Revascularization Trials, Journal of the American College of Cardiology, 1/1/2002
• "Physiological" Placebo in clinical angiogenesis and laser myocardial revascularization studies underscores the importance of blinding
  Laham RJ, Simons M, Sellke FW, Mannam A, Cohen DJ, Circulation, 1/1/2001
• Late Nuclear Perfusion Imaging Follow-up after Perivascular Implantation of FGF-2
  Ruel M, Laham RJ, Niemann D, Sellke FW, Parker JA, Circulation, 1/1/2001
• Clinical Angiogenesis and laser myocardial revascularization studies: the need for better outcome measures
  Laham RJ, Mannam A, Cohen DJ, Neimann D, Rooney P, Sellke FW, Circulation, 1/1/2001
• Biosense NOGA Mapping for Detection of Myocardial Ischemia: Comprehensive Assessment in 74 Pigs
  Beran GP, Post M, Simons M, Glogar D, Laham RJ, Journal of the American College of Cardiology, 1/1/2001
• Tissue and Myocardial Distribution of Endocardial vs Epicardial Intramyocardial Delivery of 125-I-Labeled Basic Fibroblast Growth Factor
  Laham RJ, Post M, Sellke FW, Simons M, Journal of the American College of Cardiology, 1/1/2001
• Outcome Measures in Angiogenesis and Laser Trials: Natural history of No-option Patients with Ischemic Heart Disease Who Are Not Candidates for PTCA or CABG and Who Re...
  Laham RJ, Sellke FW, Baim DS, Simons M, Journal of the American College of Cardiology, 1/1/2001
• A Randomized Blinded Clinical Trial Comparing Percutaneous Laser Myocardial Revascularization (Using Biosense LV Mapping) vs Placebo in Patients with Refractory Corona...
  Leon MB, Baim DS, Moses JW, Laham RJ, Knopf W, Circulation, 1/1/2000
• Correspondence of BIOSENSE-Guided Endocardial Catheter Maps With MRI: Influence of Number of Locations Sampled
  Pearlman JD, Wu Y, Simons M, Baim DS, Laham RJ, Journal of the American College of Cardiology, 1/1/2000
• How To Evaluate The Effect Of Angiogenic Strategies On Regional Myocardial Blood Flow?
  Sato K, Post M, Johnson R, Pearlman JD, Laham RJ, Sellke FW, Circulation, 1/1/1999
• Tissue and Myocardial Distribution of Intracoronary, Intravenous, Intrapericardial, and Intramyocardial 125I-Labeled Basic Fibroblast Growth Factor (bFGF) Favor Intram...
  Laham RJ, Rezaee M, Garcia L, Post M, Sellke FW, Baim DS, Simons M, J Am Coll Cardiol, 1/1/1999
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Lectures

• Medtronic, Corevalve Percutaenous valve Program 
  Fort Lauderdale, FL - 1/1/2012
• Left Atrial Exclusion 
  1/1/2011
• Harvard-MIT Program 
  1/1/2011
• Left Atrial Apendage Exclusion: Surgery vs Catheter based 
  San Francisco, CA - 1/1/2011
• Left Ventricular Support 
  San Francisco, CA - 1/1/2011
• Angiogenesis-Plenary lecture 
  1/1/2011
• Myogenesis Strategies 
  1/1/2011
• Carotid Stenting 
  Orlando, FL - 1/1/2011
• Future of Cardiovascular care is here 
  Lebanon - 1/1/2011
• Vascular biology group 
  Boston, MA - 1/1/2010
• Thrombolysis, Thrombectomy, and Other Mechanical Approaches to Thrombus-201 
  Washington, DC - 1/1/2010
• Septal Ablation for Hypertrophic Obstructive Cardiomyopathy-206-case 2 
  Washington, DC - 1/1/2010
• How to Treat Theater: Endovascular Disease I-Iliac and SFA Intervention 
  Washington, DC - 1/1/2010
• Imaging Guidance for Transcatheter Valve Interventions 
  Washington, DC - 1/1/2010
• 5 lectures on management of critical cardiology patients 
  1/1/2008
• IVUS 101 
  Boston, MA - 1/1/2008
• Percutaneous valve replacement 
  Chicago, IL - 1/1/2008
• Vulnerable Plaque Imaging, IVUS update, Update on percutaneous valves, Cardiac CT update 
  1/1/2008
• Ongoing Controversies in Drug Eluting Stenting 
  1/1/2008
• Bone marrow cell therapy 
  Washington, DC - 1/1/2007
• Angiogenesis, critical review of late breaking clinical trial 
  Washington, DC - 1/1/2007
• Plenary lecture on percutaneous aortic valve replacement 
  1/1/2007
• Imaging symposium 
  Riyadh, Saudi Arabia - 1/1/2007
• Digivoting session 
  Tunisia, Tunisia - 1/1/2007
• Lebanese course on revascularization 
  Beirut, Lebanon - 1/1/2007
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Other

• Coronary arteriography and revascularization for unstable angina or non-ST elevation (non-Q wave) acute myocardial infarction 
  Breall J, Laham RJ, Aroesty J, Simons M, UpToDate, BDR, Inc.
  1/1/2004
• New medical and invasive therapies for angina pectoris 
  Laham RJ, Simons M, UpToDate, BDR, Inc.
  1/1/2004
• Molecular biology of restenosis: Role of cytokines and vascular remodeling 
  Laham RJ, Post M, Simons M, UpToDate, BDR, Inc.
  1/1/2004
• Clinical trials of primary percutaneous coronary intervention in acute myocardial infarction-III 
  Gibson CM, Carrozza JP, Laham RJ, Baim DS, UpToDate, BDR, Inc.
  1/1/2004
• Clinical trials of primary percutaneous coronary intervention in acute myocardial infarction-II 
  Gibson CM, Carrozza JP, Laham RJ, Baim DS, UpToDate, BDR, Inc.
  1/1/2004
• Clinical trials of primary percutaneous coronary intervention in acute myocardial infarction-I 
  Gibson CM, Carrozza JP, Laham RJ, Baim DS, UpToDate, BDR, Inc.
  1/1/2004
• Basic mechanisms of restenosis 
  Laham RJ, Post M, Simons M, UpToDate, BDR, Inc.
  1/1/1997
• Collaterals in Coronary Artery Disease 
  Laham RJ, Simons M, UpToDate, BDR, Inc.
  1/1/1997
• Primary Stenting in Acute Myocardial Infarction 
  Laham RJ, Baim DS, UpToDate, BDR, Inc.
  1/1/1997
• Role of revascularization in the management of unstable angina 
  Laham RJ, Simons M, UpToDate, BDR, Inc.
  1/1/1996
• Controversies in cardiopulmonary resuscitation 
  Laham RJ, Simons M, UpToDate, BDR, Inc.
  1/1/1996
• Mechanical complications of acute myocardial infarction 
  Laham RJ, Simons M
  http://www.uptodate.com/contents/mechanical-complications-of-acute-myocardial-infarction
  UpToDate, Wolters Kluwer Health - 2012-03-14
• Intraaortic balloon pump counterpulsation 
  Laham RJ, Aroesty JM
  http://www.uptodate.com/contents/intraaortic-balloon-pump-counterpulsation
  UpToDate, Wolters Kluwer Health - 2013-04-11
• Transmyocardial laser revascularization for management of refractory angina 
  Laham RJ, Simons M
  http://www.uptodate.com/contents/transmyocardial-laser-revascularization-for-management-of-refractor
  UpToDate, Wolters Kluwer Health - 2012-09-04
• Suboptimal reperfusion after primary percutaneous coronary intervention in acute ST elevation myocardial infarction 
  Laham RJ, Gibson CM, Carrozza JP
  http://www.uptodate.com/contents/suboptimal-reperfusion-after-primary-percutaneous-coronary-interven
  UpToDate, Wolters Kluwer Health - 2012-06-11
• Primary percutaneous coronary intervention versus fibrinolysis in acute ST elevation myocardial infarction: Clinical trials 
  Laham RJ, Gibson CM, Carrozza JP
  http://www.uptodate.com/contents/primary-percutaneous-coronary-intervention-versus-fibrinolysis-in-a
  UpToDate, Wolters Kluwer Health - 2012-06-26
• Primary percutaneous coronary intervention in acute ST elevation myocardial infarction: Periprocedural management 
  Laham RJ, Gibson CM, Carrozza JP
  http://www.uptodate.com/contents/primary-percutaneous-coronary-intervention-in-acute-st-elevation-my
  UpToDate, Wolters Kluwer Health - 2013-02-19
• Primary percutaneous coronary intervention in acute ST elevation myocardial infarction: Determinants of outcome 
  Laham RJ, Gibson CM, Pinto DS, Carrozza JP
  http://www.uptodate.com/contents/primary-percutaneous-coronary-intervention-in-acute-st-elevation-my
  UpToDate, Wolters Kluwer Health - 2013-01-21
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