RolandLee-ShingChuMD

Pediatric Hematology & Oncology • Detroit, MI

Assistant Professor, Pediatrics, Wayne State University School of Medicine

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Office
3901 Beaubien St
Detroit, MI 48201
Phone+1 313-966-0660

Fax+1 313-745-5420
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Education & Training

Emory University School of MedicineFellowship, Pediatric Hematology/Oncology, 2002 - 2005
Children's Hospital of MichiganResidency, Pediatrics, 1999 - 2002
Wayne State University School of MedicineClass of 1999

Certifications & Licensure

MI State Medical License 1999 - 2024
GA State Medical License 2002 - 2005
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) Start of enrollment: 2006 Dec 01
Completed
Phase 3
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Monitor Response to Treatment in Neuroblastoma Using 3&Apos;-Deoxy-3&Apos;-Fluorothymidine- Positron Emission Tomography (FLT-PET) Start of enrollment: 2011 Feb 01
Unknown status
Not Applicable
Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant Start of enrollment: 2013 Mar 21
Completed
Phase 3
Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients. Start of enrollment: 2013 Aug 20
Completed
Phase 2
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Publications & Presentations

PubMed

Clofarabine monotherapy in aggressive, relapsed and refractory Langerhans cell histiocytosis.
Agrusa, J. E., Deevyashali Parekh, Howard Lin, Akanksha Batajoo, Erin Peckham-Gregory, Vivekanudeep Karri, Whitney Stanton, Brooks Scull, Ryan Fleishmann, Nader El-Mal...> ;British Journal of Haematology. 2024 Mar 19
Patterns and correlates of preserved humoral immunity to vaccines in children following allogeneic hematopoietic stem cell transplantation
Eman Al-Antary, Meret Henry, Jessica L. Spruit, Maxim Yankelevich, Roland Chu, Yaddanapudi Ravindranath, Süreyya Savaşan> ;Pediatric Transplantation. 2021 Aug 1
1 citations
Delayed Granulocyte Colony-Stimulating Factor (G-CSF) Administration after Chemotherapy Reduces Total G-CSF Doses without Affecting Neutrophil Recovery in a Randomized...
Maxim Yankelevich, David J. Hoogstra, Judith Abrams, Roland Chu, Kanta Bhambhani, Jeffrey W. Taub> ;Pediatric Hematology and Oncology. 2020 Jul 9
1 citations
Role of Initiating Supportive Care Preceding Veno-occlusive Disease Diagnosis Following Allogeneic Hematopoietic Stem Cell Transplantation in Children.
Patricia Rayner, Jessica L. Spruit, Roland Chu, Maxim Yankelevich, Meret Henry, Yaddanapudi Ravindranath, Süreyya Savaşan> ;Journal of Pediatric Hematology/oncology. 2019 Aug 1
2 citations
Ethanol lock for CLABSI in children with cancer: a matter of (dwell) time?
Eric McGrath, Nahed Abdel-Haq, Basim I. Asmar, Roland Chu, Madhvi Rajpurkar> ;The Lancet. Infectious Diseases. 2018 Oct 1
11 citations
Changes in Bi-ventricular Function After Hematopoietic Stem Cell Transplant as Assessed by Speckle Tracking Echocardiography
Stuart Covi, Yaddanapudi Ravindranath, Ahmad Farooqi, Süreyya Savaşan, Roland Chu, Sanjeev Aggarwal> ;Pediatric Cardiology. 2018 Feb 1
Small Split Doses of CD34+ Peripheral Blood Stem Cells to Support Repeated Cycles of Nonmyeloablative Chemotherapy.
Maxim Yankelevich, Süreyya Savaşan, Igor Dolgopolov, Roland Chu, George Mentkevich> ;Case Reports in Oncological Medicine. 2017 Nov 12
9 citations
Extracorporeal membrane oxygenation outcomes in children with hemophagocytic lymphohistiocytosis
Katherine Cashen, Roland Chu, Justin D Klein, Peter Rycus, John M. Costello> ;Perfusion. 2017 Mar 1
36 citations
Mechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells
Jun Ma, Xinyu Li, Yongwei Su, Jianyun Zhao, Daniel A. Luedtke, Valeria Epshteyn, Holly Edwards, Guan Wang, Zhihong Wang, Roland Chu, Jeffrey W. Taub, Hai Lin, Yue Wang...> ;Scientific Reports. 2017 Feb 8
156 citations
Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells.
Xiaojia Niu, Jianyun Zhao, Jun Ma, Chengzhi Xie, Holly Edwards, Guan Wang, J. Timothy Caldwell, Shengyan Xiang, Xiaohong Zhang, Roland Chu, Zhihong J. Wang, Hai Lin, J...> ;Clinical Cancer Research. 2016 Sep 1
7 citations
Gene Signature of High White Blood Cell Count in B-Precursor Acute Lymphoblastic Leukemia.
Holly Edwards, Mara B. Rubenstein, Alan A. Dombkowski, J. Timothy Caldwell, Roland Chu, Ana C. Xavier, Ryan Thummel, Melody N. Neely, Larry H. Matherly, Yubin Ge, Jeff...> ;Plos One. 2016 Aug 18
28 citations
Synergistic anti-leukemic interactions between panobinostat and MK-1775 in acute myeloid leukemia ex vivo
Wenxiu Qi, Wenbo Zhang, Holly Edwards, Roland Chu, Gerard J. Madlambayan, Jeffrey W. Taub, Zhihong Wang, Yue Wang, Chunhuai Li, Hai Lin, Yubin Ge> ;Cancer Biology & Therapy. 2015 Nov 3
46 citations
Who Treats Adolescents and Young Adults with Cancer? A Report from the AYA HOPE Study
Helen Parsons, Linda C. Harlan, Susanne Schmidt, Theresa H.M. Keegan, Charles F. Lynch, Erin E. Kent, Xiao-Cheng Wu, Stephen M. Schwartz, Roland Chu, Gretchen Keel, As...> ;Journal of Adolescent and Young Adult Oncology. 2015 Sep 1
9 citations
The Impact of Ethanol Lock Therapy on Length of Stay and Catheter Salvage in Pediatric Catheter-Associated Bloodstream Infection
Manu Chaudhary, Muhammad Bilal, Wei Du, Roland Chu, Madhvi Rajpurkar, Eric McGrath> ;Clinical Pediatrics. 2014 May 7
78 citations
Medical care in adolescents and young adult cancer survivors: what are the biggest access-related barriers?
Theresa H.M. Keegan, Li Tao, Mindy C. DeRouen, Xiao-Cheng Wu, Pinki Prasad, Charles F. Lynch, Margarett Shnorhavorian, Brad Zebrack, Roland Chu, Linda C. Harlan, Ashle...> ;Journal of Cancer Survivorship. 2014 Jan 10
6 citations
Reviewing the Follow-up Care of Pediatric Patients’ Status Post–Hematopoietic Stem Cell Transplantation for the Primary Care Pediatrician
Rohith Jesudas, Aimee Malesky, Roland Chu, Howard Fischer, Deepak Kamat> ;Clinical Pediatrics. 2013 Apr 5
10 citations
Patterns of Failure in Patients With Primary Intracranial Germinoma Treated With Neoadjuvant Chemotherapy and Radiotherapy
Peter Paximadis, Abhirami Hallock, Kanta Bhambhani, Roland Chu, Sandeep Sood, Zhihong Wang, Andre Konski> ;Pediatric Neurology. 2012 Sep 1
19 citations
Short-Dwell Ethanol Lock Therapy in Children Is Associated With Increased Clearance of Central Line–Associated Bloodstream Infections
Eric McGrath, Ralph Salloum, Xinguang Chen, Yifan Jiang, Kathrina Boldt-MacDonald, Cristie Becker, Roland Chu, Jocelyn Y. Ang> ;Clinical Pediatrics. 2011 May 27
47 citations
Comparison of outcomes after transplantation of G-CSF-stimulated bone marrow grafts versus bone marrow or peripheral blood grafts from HLA-matched sibling donors for p...
Chu, R., Brazauskas, R., Kan, F., Bashey, A., Bredeson, C., Camitta, B., Chiang, K. Y., Frangoul, H., Gale, R. P., Gee, A., George, B., Goldman, F. D., Gross, T. G., G...> ;Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2010 Nov 3
122 citations
Use of replicating oncolytic adenoviruses in combination therapy for cancer
Roland L. Chu, Dawn E. Post, Fadlo R. Khuri, Erwin G. Van Meir> ;Clinical Cancer Research. 2004 Aug 15
3 citations
Suppression of Hodgkin's disease in a patient with Cushing's syndrome.
Della L. Howell, John Bergsagel, Roland L. Chu, Lillian R. Meacham> ;Journal of Pediatric Hematology/oncology. 2004 May 1
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Abstracts/Posters

Oryzocytosis: A Novel Morphological Variant of Hereditary Elliptocytosis Associated with a Novel Mutation in _-Spectrin (SPTB c154 C>T p.Arg52Trp)
Roland Chu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019