RoohiIsmail-KhanMDMSC

PubMed

• Clonal Hematopoiesis as a Molecular Risk Factor for Doxorubicin-Induced Cardiotoxicity: A Proof-of-Concept Study.
  Jamila Mammadova, Christelle Colin-Leitzinger, Diep Nguyen, Rahul Mhaskar, Shridar Ganesan, Yi-Han Tang, Mingxiang Teng, Roohi Ismail-Khan, Nancy Gillis> ;JCO Precision Oncology. 2023 Sep 1
• 2 citations
  Translational Genomic Research: The Association between Genetic Profiles and Cognitive Functioning or Cardiac Function Among Breast Cancer Survivors Completing Chemoth...
  Jong Y Park, Cecile A Lengacher, Richard R Reich, Hyun Y Park, Junmin Whiting, Anh Thy Nguyen, Carmen Rodríguez, Hongdao Meng, Sara Tinsley, Katterine Chauca, Liliana ...> ;Biological Research for Nursing. 2022 Oct 1
• 5 citations
  Barriers and facilitators to taking CDK4/6 inhibitors among patients with metastatic breast cancer: a qualitative study.
  Claire C Conley, McKenzie McIntyre, Nicole A Pensak, Filipa Lynce, Deena Graham, Roohi Ismail-Khan, Katherine Lopez, Susan T Vadaparampil, Suzanne C O'Neill> ;Breast Cancer Research and Treatment. 2022 Apr 1
• 2 citations
  Case Report: Initial Treatment Adjustments and Complications in Ovarian Cancer Patient With Inborn Error of Immunity.
  Jamila Mammadova, Anna Redden, Rachel Cruz, Boglarka Ujhazi, Maryssa Ellison, Tyra Gatewood, Carla Duff, Anthony Canella, Charurut Somboonwit, Chakrapol Sriaroon, Jose...> ;Frontiers in Oncology. 2022 Jan 1
• Corrigendum: Case report: Initial treatment adjustments and complications in ovarian cancer patient with inborn error of immunity.
  Jamila Mammadova, Anna Redden, Rachel Cruz, Boglarka Ujhazi, Sumai Gordon, Maryssa Ellison, Tyra Gatewood, Carla Duff, Anthony Cannella, Charurut Somboonwit, Chakrapol...> ;Frontiers in Oncology. 2022 Jan 1
• 13 citations
  A Phase Ib Dose Escalation Trial of RO4929097 (a γ-secretase inhibitor) in Combination with Exemestane in Patients with ER + Metastatic Breast Cancer (MBC)
  Julie Means-Powell, Ingrid A. Mayer, Roohi Ismail-Khan, Luis Del Valle, Debra A. Tonetti, Vandana G. Abramson, Melinda Sanders, Richard M Lush, Claudia Sorrentino, Sam...> ;Clinical Breast Cancer. 2021 Oct 28
• #JACCCardioOnc: Evolution of a Dedicated Social Media Strategy for JACC: CardioOncology.
  Sherry-Ann Brown, Eric H. Yang, Nosheen Reza, Avirup Guha, Roohi Ismail-Khan, Naveen Pemmaraju, Michael G. Fradley, Juan Lopez-Mattei> ;JACC. Cardiooncology. 2021 Sep 1
• 6 citations
  The Role and Impact of Social Media in Cardio-oncology During the COVID-19 Pandemic.
  Jennifer M. Kwan, Mariana L. Henry, Briana Christophers, Kamala P Tamirisa, Ritu Thamman, Diego Sadler, Niti R. Aggarwal, Richard Cheng, Purvi Parwani, Susan Dent, Roo...> ;Current Oncology Reports. 2021 Jul 14
• 3 citations
  Patient reported physical and mental health changes associated with a comprehensive cardiovascular risk reduction program for women with breast cancer receiving potent...
  Michael G. Fradley, Mohammed Alomar, Marcus W. Kilpatrick, Bernadette Shields, Nhi Tran, Amey Best, Erika Bianco, R Ashton Vautier, Kevin E. Kip, Theresa M. Beckie, Ro...> ;Cardio-Oncology. 2021 May 31
• 42 citations
  Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System: Effects and Modifications: A Scientific Sta...
  Tochi M. Okwuosa, Alicia K. Morgans, June-Wha Rhee, Kerryn W. Reding, Sally Maliski, Juan-Carlos Plana, Annabelle Santos Volgman, Kendall F Moseley, Charles B Porter, ...> ;Circulation. Genomic and Precision Medicine. 2021 Apr 26
• 8 citations
  Reaching Across the Aisle: Cardio-Oncology Advocacy and Program Building.
  Diego Sadler, Anita Arnold, Joerg Herrmann, Andres Daniele, Carolina Maria Pinto Domingues Carvalho Silva, Arjun K. Ghosh, Sebastian Szmit, Roohi Ismail Khan, Luis E. ...> ;Current Oncology Reports. 2021 Apr 14
• 19 citations
  Effect of Taxane Chemotherapy With or Without Indoximod in Metastatic Breast Cancer: A Randomized Clinical Trial.
  Veronica Mariotti, Hyo S. Han, Roohi Ismail-Khan, Shou-Ching Tang, Patrick M. Dillon, Alberto J. Montero, Andrew Poklepovic, Susan A. Melin, Nuhad K. Ibrahim, Eugene P...> ;JAMA Oncology. 2021 Jan 1
• 13 citations
  Perspectives on the COVID-19 pandemic impact on cardio-oncology: results from the COVID-19 International Collaborative Network survey.
  Diego Sadler, Jeanne M. DeCara, Joerg Herrmann, Anita Arnold, Arjun K. Ghosh, Husam Abdel-Qadir, Eric H. Yang, Sebastian Szmit, Nausheen Akhter, Monika Leja, Carolina ...> ;Cardio-Oncology. 2020 Nov 27
• 11 citations
  Cardiovascular care of the oncology patient during COVID-19: An expert consensus document from the ACC Cardio-Oncology and Imaging Councils.
  Lauren A. Baldassarre, Eric H. Yang, Richard Cheng, Jeanne M. DeCara, Susan Dent, Jennifer E. Liu, Lawrence G. Rudski, Jordan B. Strom, Paaladinesh Thavendiranathan, A...> ;Journal of the National Cancer Institute. 2020 Nov 12
• 15 citations
  Hypertensive Cardiotoxicity in Cancer Treatment-Systematic Analysis of Adjunct, Conventional Chemotherapy, and Novel Therapies-Epidemiology, Incidence, and Pathophysio...
  Robin Chung, Sara Tyebally, Daniel H Chen, Vikas Kapil, J Malcolm Walker, Daniel Addison, Roohi Ismail-Khan, Avirup Guha, Arjun K. Ghosh> ;Journal of Clinical Medicine. 2020 Oct 18
• 7 citations
  Florida Inter-Specialty Collaborative Project to Improve Cardio-Oncology Awareness and Identify Existing Knowledge Gaps.
  Diego Sadler, Michael G. Fradley, Roohi Ismail-Khan, Luis E. Raez, Deepti Bhandare, Leah Elson, David Perloff, Patricia Guerrero, Zeina Nahleh, Anita Arnold> ;JACC. Cardiooncology. 2020 Sep 1
• 27 citations
  Optimizing Cardiovascular Health in Patients With Cancer: A Practical Review of Risk Assessment, Monitoring, and Prevention of Cancer Treatment-Related Cardiovascular ...
  Susan Dent, Robin Kikuchi, Lavanya Kondapalli, Roohi Ismail-Khan, Christine Brezden-Masley, Ana Barac, Michael G. Fradley> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2020 Mar 26
• 200 citations
  Cardiovascular Events Among Adults Treated With Chimeric Antigen Receptor T-Cells (CAR-T)
  Raza M. Alvi, Matthew J. Frigault, Michael G. Fradley, Michael D. Jain, Syed S. Mahmood, Magid Awadalla, Dae Hyun Lee, Daniel A. Zlotoff, Lili Zhang, Zsofia D. Drobni,...> ;Journal of the American College of Cardiology. 2019 Dec 24
• 12 citations
  Expression of the BAD pathway is a marker of triple-negative status and poor outcome.
  Bernadette M. Boac, Forough Abbasi, Roohi Ismail-Khan, Yin Xiong, Atif Siddique, Hannah Park, Mingda Han, Daryoush Saeed-Vafa, Hatem Soliman, Brendon Henry, M. Juliana...> ;Scientific Reports. 2019 Nov 25
• 8 citations
  Translational genomic research: the role of genetic polymorphisms in MBSR program among breast cancer survivors (MBSR[BC]).
  Jong Y. Park, Cecile A. Lengacher, Richard R. Reich, Carissa B. Alinat, Sophia Ramesar, Alice Le, Carly L. Paterson, Michelle L. Pleasant, Hyun Y. Park, John V. Kiluk,...> ;Translational Behavioral Medicine. 2019 Jul 16
• 30 citations
  A Phase II Trial of Selinexor (KPT‐330) for Metastatic Triple‐Negative Breast Cancer
  Michael R. Shafique, Roohi Ismail-Khan, Martine Extermann, Daniel C. Sullivan, Dawn Goodridge, David Boulware, Deanna Hogue, Hatem Soliman, Hung Khong, Hyo S. Han> ;The Oncologist. 2019 Jul 1
• 44 citations
  Paclitaxel With Inhibitor of Apoptosis Antagonist, LCL161, for Localized Triple-Negative Breast Cancer, Prospectively Stratified by Gene Signature in a Biomarker-Drive...
  Aditya Bardia, Marina Parton, Sherko Kümmel, Laura G. Estévez, Chiun-Sheng Huang, Javier Cortes, Manuel Ruiz-Borrego, Melinda L. Telli, Paloma Martín-Martorell, Rafael...> ;Journal of Clinical Oncology. 2018 Sep 20
• 17 citations
  Rates and risk of arrhythmias in cancer survivors with chemotherapy-induced cardiomyopathy compared with patients with other cardiomyopathies
  Michael G. Fradley, Federico Viganego, Kevin E. Kip, Angel Martin, Aarti Patel, Roohi Ismail-Khan, Sanders H. Chae, Bengt Herweg, Arthur J. Labovitz> ;Open Heart. 2017 Dec 1
• 40 citations
  Developing a Comprehensive Cardio-Oncology Program at a Cancer Institute: The Moffitt Cancer Center Experience.
  Michael G. Fradley, Allen Brown, Bernadette Shields, Federico Viganego, Rongras Damrongwatanasuk, Aarti Patel, Gregory Hartlage, Natalee Roper, Julie Jaunese, Larry Ro...> ;Oncology Reviews. 2017 Jul 18
• 15 citations
  An Exploratory Study to Determine Whether BRCA1 and BRCA2 Mutation Carriers Have Higher Risk of Cardiac Toxicity
  Monique Sajjad, Michael G. Fradley, Weihong Sun, Jongphil Kim, Xiuhua Zhao, Tuya Pal, Roohi Ismail-Khan> ;Genes. 2017 Feb 2
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Journal Articles

• Beta-catenin Expression Patterns in Matched Pre and Post Neoadjuvant Chemotherapy Resistant Breast Cancer  
  Rosa M, Han HS, Ismail-Khan R, Allam-Nandyala P, Bui M, Annals of Clinical and Laboratory Science, 1/1/2015
• A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors  
  Soliman HH, Jackson E, Neuger T, Dees C, Harvey D, Han H, Ismail-Khan R, Minton SE, Vahanian N, Link C, Sullivan D, Antonia S, Oncotarget, 1/21/2014
• Randomized Phase II, Double-Blind, Placebo-Controlled Study of Exemestane With or Without Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic Estro...  
  Yardley D, Ismail-Khan R, Trepel J, et al, Journal Of Clinical Oncology, 1/6/2013
• Comparison of breast magnetic resonance imaging clinical tumor size with pathologic tumor size in patients status post-neoadjuvant chemotherapy  
  Williams M, Eatrides J, Kim J, Talwar H, Esposito N, Szabunio M, Ismail-Khan R, Kiluk J, Lee M, Laronga C, Khakpour N, Am Jnl of Surgery, 1/1/2013
• Control of brain metastases for HER2-positive breast cancer with bevacizumab: a report of three patients  
  Sajjad M. Pan E, Minton S, Ismail-Khan R, J of Solid Tumors, 1/1/2013
• Randomized trial using the GnRH agonist triptorelin for the preservation of ovarian function during (neo)adjuvant chemotherapy for breast cancer  
  Munster PN, Moore AP, Ismail-Khan R, Cox CE, Lacevic M, Gross-King M, Xu P, Carter WB, Minton SE, J Clin Oncol, 1/10/2012
• HER2-positive breast cancer in men who also developed thyroid cancer  
  Bardhan P, Bui M, Minton S, Loftus L, Carter WB, Laronga C, Ismail-Khan R, Ann Clin Lab Sci, 1/1/2012
• A Phase I/II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen in patients with hormone-resistant breast cancer  
  Munster PN, Thurn KT, Thomas S, Raha P, Lacevic M, Miller A, Melisko M, Ismail-Khan R, Rugo H, Moasser M, Minton SE, Br J Cancer, 1/7/2011
• Preservation of ovarian function in young women treated with neoadjuvant chemotherapy for breast cancer: a randomized trial using the GnRH agonist (triptorelin) during...  
  Ismail-Khan R, Minton SE, Cox C, et al, J Clin Oncol, 1/1/2008
• Nuclear excision repair-based personalized therapy for non-small cell lung cancer: from hypothesis to reality  
  Simon GR, Ismail-Khan R, Bepler G, Int J Biochem Cell Biol, 1/1/2007
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Abstracts/Posters

• A Phase II, open label, neoadjuvant, randomized study of LCL161 with paclitaxel in patients with triple-negative breast cancer (TNBC)
  Bardia A, Kummel S, Garcia-Estevez L, Huang CS, Cortes Castan J, Ruiz Borrego M, Telli ML, Lluch Hernandez A, Lopez R, Beck JT, Ismail-Khan R, Chen SC, Hurvitz S, Maye..., ASCO, Chicago, IL, 1/1/2015
• The BCL2 antagonist of cell death (BAD) signaling pathway and phospho-BAD protein levels are associated with triple negative breast cancer clinical development and cli...
  Marchion DC, Xiong Y, Ismail-Khan R, Abbasi F, Bou Zgheib N, Ramirez IJ, Bush SH, Hakam A, Judson PL, Lancaster JM, SGO 45th Annual Meeting, Tampa, FL, 1/21/2014
• AKT survival signaling and phospho-AKT expression are associated with triple negative breast cancer development and clinical outcome
  Marchion DC, Ismail-Khan R, Abbasi F, Boac B, Xiong Y, McClung C, Khulpateea BR, Bush SH, Hakam A, Lancaster JM, SGO 45th Annual Meeting, Tampa, FL, 1/21/2014
• PhaseIb/II study of LEE011, Alpelisib (BYL719), and Letrozole in ER+, HER2-Breast Cancer: Safety, Preliminary Efficacy, and Molecular Analysis
  Juric D, Campone M, Ismail-Khan R, DeBoer R, Garcia Estevez L, Hamilton E, Mayer I, Asano S, Bhansali S, Zhang V, Hewes B, Munster P, SABCS, San Antonio, TX, 1/1/2014
• A phase ½ study of Ad.p53 DC vaccine with indoximod immunotherapy in metastatic breast cancer
  Soliman, H, Minton S, Ismail-Khan R, Han H, Vahanian N, Link C, Kennedy G, Streicher H, Sullivan D, Antonia S, San Antonio Breast Cancer Symposium, 1/1/2014
• Safety and Efficacy of MK-8669 (Ridaforolimus) + MK-2206 (AKT inhibitor) in patients with advanced breast cancer with P13K pathway dependence
  Piha-Paul S, Ismail-Khan R, Munster P, Hollebecque A, Argiles, G, Guren T, Cheng J, Wang R, Swift A, Tosolini A, Sullivan D, Gupta S, IMPAKT, Brussels, Belgium, 1/1/2014
• Prognostic factors and outcomes in triple negative breast cancer – A single institutional experience
  Apuri S, Sun W, Bardhan P, Minton S, Soliman H, Han H, Lee JH, Fulp W, Ismail-Khan R, San Antonio Breast Cancer Symposium, 1/1/2013
• A phase-II randomized, open-label, neoadjuvant study of LCL161, an oral antagonist of inhibitor of apoptosis proteins, in combination with paclitaxel in patients with ...
  Lluch-Hernandez A, Simon AR, Huang C, Castan JC, Ruiz-Borrego M, Telli M, Ismail-Khan R, Parton M, Tseng LM, Chen SC, Schmid P, Mayer I, Hurvitz S, Garcia-Estevez L, A..., San Antonio Breast Cancer Symposium, 1/1/2013
• Triple Negative Breast Cancer and Age: Tumor Characteristics and Outcomes.
  Loftus L, Sokol G, Ismail-Khan R, 13th Conference of the International Society of Geriatric Oncology – SIOG, Copenhagen, Denmark, 1/1/2013
• A Phase I Dose Escalation Trial of RO4929097 (y-Secretase Inhibitor) Administered in combination with Exemestane in Pre-and Postmenopausal Patients with ER+/HER 2 Neu-...
  Means-Powell JA, Minton SE, Mayer IA, Abramson VG, Ismail-Khan R, Arteaga CL, Ayers DA, Sanders MS, Lush RM, Miele LL, San Antonio Breast Cancer Symposium, 1/1/2012
• Exploratory Study to Determine if BRCA1 and BRCA2 Mutation Carriers Have Higher Risk of Cardiac Toxicity.
  Ismail-Khan R, Sajjad M, Sun W, Soliman HH, H. Han HS, Minton SE, Lancaster JM, Pal T, International Cardio-Oncology Society Annual Meeting, Milan, Italy, 1/1/2012
• An Exploratory Study to Determine if BRCA1 and BRCA2 Mutation Carriers Have Higher Risk of Cardiac Toxicity
  Ismail-Khan R, Sajjad M, Sun W, Soliman HH, Han HS, Minton SE, Lancaster JM, Pal T, ASCO, 1/1/2012
• A Phase I Study of 1-methyl-D-tryptophan in Combination with Docetaxel in Metastatic Solid Tumors
  Jackson E, Minton SE, Ismail-Khan R, Han HS, Neuger A, Antonia S, Sullivan D, Soliman HH, ASCO, 1/1/2012
• Increased Risk of Heart Failure in BRCA Mutation Carriers
  Sajjad M, Ismail-Khan R, American Federation of Medical Research, Southern Regional Meetings, New Orleans, LA, 1/1/2012
• Positive Results of ENCORE-301, A Phase 2 Randomized, Double-blind Placebo-controlled Study in Postmenopausal Women with Locally Recurrent or Metastatic Estrogen Recep...
  Yardley DA, Ismail-Khan R, Klein PM, San Antonio Breast Cancer Symposium, 1/1/2011
• Positive Results of ENCORE-301, A Phase 2 Randomized, Double-blind Placebo-controlled Study in Postmenopausal Women with Locally Recurrent or Metastatic Estrogen Recep...
  Yardley DA, Ismail-Khan R, Klein PM, ASCO Breast, 1/1/2011
• A double blind, randomized, placebo controlled phase II study of the steroidal aromatase inhibitor exemestane with and without the isoform selective histone deacetylas...
  Yardley D, Ismail-Khan R, Eakle J, Hagan K, Miller K, Paul D, Borges V, Helsten T, Kroener J, Melichar B, Tkaczuk K, ASCO, 1/1/2011
• Synergy of Ixabepilone and Dasatinib in Triple Negative Breast Cancer Cell Lines
  Ismail-Khan R, Marchion DC, Cubitt CL, Lancaster JM, San Antonio Breast Cancer Symposium, 1/1/2010
• The influence of the BAD apoptosis pathway on breast cancer progression and relapse-free survival after adjuvant treatment
  Ismail-Khan R, Marichion DC, Xiong Y, Fulp WJ, Kamath SG, Eschrich SA, Chen DT, Lancaster JM, San Antonio Breast Cancer Symposium, 1/1/2010
• Modi S, Ismail-Khan R, Munster P, Lucas M, Galluppi GR, Tangri S, Chen Y, Mason Y, Chris MS, Moulder S, San Antonio Breast Cancer Symposium, 1/1/2010
• Urinary Incontinence and its Impact on Quality of Life in Breast Cancer Survivors
  Donovan KA, Boyington AR, Ismail-Khan R, Wyman JF, Moffitt Cancer Center, University of Minnesota, American Psychosocial Oncology Society’s Annual Meeting, New Orleans, LA, 1/1/2010
• Neoadjuvant Intratumoral Injection of Dendritic Cells in Breast Cancer
  Minton S, Gabrilovich D, Lacevic M, Laronga C, Lee C, Kiluk J, Khakpour N, Bui M, Soliman H, Ismail-Khan R, Han H, Munster P, Janssen W, Cowan K, Talmadge J, Reed E, San Antonio Breast Cancer Symposium, 1/1/2009
• Clinical Phase II Study if Vorinostat, a Hydroxamic Deacetylase Inhibitor, in Combination with Tamoxifen To Reverse Acquired Hormone Resistance in Breast Cancer Patien...
  Munster PN, Lacevic M, Thomas S, Ismail-Khan R, Rugo H, Melisko M, Minton SE, San Antonio Breast Cancer Symposium, 1/1/2009
• Phase II trial of the histone deacetylase inhibitor, vorinostat, to restore hormone sensitivity to the antiestrogen tamoxifen in patients with advanced breast cancer w...
  Munster PN, Lacevic M, Thomas S, Christian C, Ismail-Khan R, Melisko M, Rugo H, Minton SE, ASCO, 1/1/2009
• Preservation of Ovarian Function in Young Women Treated with (NEO) Adjuvant Chemotherapy for Breast Cancer: A Randomized Trial Using the GnRH Agonist (Triptorelin) Dur...
  Ismail-Khan R, Minton SE, Cox C, Sims I, Lacevic M, Carter B, Munster P, ASCO, 1/1/2008
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Lectures

• Cardiac Complications from Chemotherapy and The New Cardio-Oncology Program 
  1/12/2015
• Issues in Breast Cancer Therapy 
  University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL - 1/1/2015
• Triple Negative breast cancer 
  1/1/2015
• Advances in Treatment of Metastatic Breast Cancer 
  1/17/2014
• Metaplastic, Medullary and Other Less Common Types of Breast Cancer 
  1/17/2013
• Clinical and Research Advances in Treatment of Breast Cancer 
  Tampa, FL - 1/1/2013
• What is Cancer? 
  1/15/2012
• Breast Cancer – What the Internist Needs to Know 
  Tampa, FL - 1/1/2012
• The Importance of Promoting Breast Cancer Health 
  Tallahassee Memorial Hospital, Tallahassee, FL - 1/10/2011
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Other

• Cardio-Oncology: An Important New Specialty to Improve Patient Outcomes 
  Ismail-Khan R and Fradley M
  University of South Florida and Moffitt Cancer Center - 1/1/2015
• Triple Negative Breast Cancer 
  Ismail-Khan R, International Hospital and Equipment (IHE), PanGlobal Media
  1/1/2010
• Why Focus on Triple Negative Breast Cancer? 
  Ismail-Khan R, Factors Publications