RossLLevineMD

PubMed

• Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes.
  B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene Lee, Wisam A Fares, Satyam Patel, Arati Sharma, Aaron D V...> ;Blood Advances. 2024 Mar 12
• Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity.
  Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde A Miles, Robert L Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Yuya Sasaki, Asiri Ediriwic...> ;Leukemia. 2024 Mar 11
• High-risk and silent clonal hematopoietic genotypes in patients with nonhematologic cancer.
  Aaron J Stonestrom, Kamal N Menghrajani, Sean M Devlin, Sebastià Franch-Expósito, Ryan N Ptashkin, Swara Y Patel, Barbara Spitzer, Xiaodi Wu, Justin Jee, Pablo Sánchez...> ;Blood Advances. 2024 Feb 27
• Development of Resistance to Type II JAK2 Inhibitors in MPN Depends on AXL Kinase and Is Targetable.
  Codilupi, T., Szybinski, J., Arunasalam, S., Jungius, S., Dunbar, A., Stivala, S., Brkic, S., Albrecht, C., Vokalova, L., Yang, J., Buczak, K., Ghosh, N., Passweg, J.,...> ;Clinical Cancer Research. 2024 Feb 1
• 4 citations
  Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction.
  Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens...> ;Nature Aging. 2024 Mar 1
• 2 citations
  A study to assess the efficacy of enasidenib and risk-adapted addition of azacitidine in newly diagnosed IDH2-mutant AML.
  Cai, S., Huang, Y., Lance, J., Mao, H., Dunbar, A., McNulty, S., Druley, T., Li, Y., Baer, M., Stock, W., Kovacsovics, T., Blum, W., Schiller, G., Olin, R., Foran, J.,...> ;Blood Advances. 2024 Jan 23
• 8 citations
  Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer.
  Arcila, M. E., Arcila, M. E., Arcila, M. E., Arcila, M. E., Suehnholz, S., Nissan, M., Zhang, H., Kundra, R., Nandakumar, S., Lu, C., Carrero, S., Dhaneshwar, A., Fern...> ;Cancer Discovery. 2024 Jan 12
• 2 citations
  Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms.
  Andrew J Dunbar, Robert L Bowman, Young C Park, Kavi O'Connor, Franco Izzo, Robert M Myers, Abdul Karzai, Zach Zaroogian, Won Jun Kim, Ines Fernandez-Maestre, Michael ...> ;Cancer Discovery. 2024 Jan 12
• 2 citations
  FLT3 tyrosine kinase inhibition modulates PRC2 and promotes differentiation in acute myeloid leukemia.
  Sung, P., Pamela J Sung, Murugan Selvam, Simone S Riedel, Hongbo M Xie, Katie Bryant, Bryan Manning, Gerald B Wertheim, Katarzyna Kulej, Lucie Pham, Robert L Bowman, J...> ;Leukemia. 2024 Feb 1
• Development of a customizable mouse backbone spectral flow cytometry panel to delineate immune cell populations in normal and tumor tissues.
  Ana Leda F Longhini, Inés Fernández-Maestre, Matthew G Wereski, Shoron Mowla, Scott W Lowe, Rui Gardner, Margaret C Kennedy, Wenbin Xiao, Ross L Levine> ;Frontiers in Immunology. 2024 Jan 1
• 1 citations
  Suppression of IL-1β promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis.
  Fidler, T., Kim, E., Hardaway, B., Pauli, J., Xue, C., Abramowicz, S., Xiao, T., O'Connor, K., Sachs, N., Wang, N., Maegdefessel, L., Dunbar, A., Levine, R., Reilly, M...> ;Nature Cardiovascular Research. 2024 Jan 1
• Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms.
  Jessica E Pritchard, Juliette E Pearce, Inge A M Snoeren, Stijn N R Fuchs, Katrin Götz, Fabian Peisker, Silke Wagner, Adam Benabid, Niklas Lutterbach, Vanessa Klöker, ...> ;Cell Reports. 2024 Jan 23
• Author Correction: Clonal hematopoiesis, aging and Alzheimer's disease.
  Pablo Sánchez Vela, Jennifer J Trowbridge, Ross L Levine> ;Nature Medicine. 2024 Jan 1
• Deep generative model deciphers derailed trajectories in acute myeloid leukemia.
  Achille Nazaret, Joy Linyue Fan, Vincent-Philippe Lavallée, Vaidotas Kiseliovas, Ignas Masilionis, Jaeyoung Chun, Robert L Bowman, Shira E Eisman, James Wang, Lingting...> ;Biorxiv. 2023 Nov 15
• Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity.
  Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde A Miles, Robert L Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Yuya Sasaki, Asiri Ediriwic...> ;Research Square. 2023 Nov 6
• 1 citations
  Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer.
  Yang Feng, Qingchen Yuan, Rachel C Newsome, Troy Robinson, Robert L Bowman, Ashley N Zuniga, Kendra N Hall, Cassandra M Bernsten, Daniil E Shabashvili, Kathryn I Krajc...> ;The Journal of Experimental Medicine. 2023 Nov 6
• Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing.
  Ryan N Ptashkin, Mark D Ewalt, Gowtham Jayakumaran, Iwona Kiecka, Anita S Bowman, JinJuan Yao, Jacklyn Casanova, Yun-Te David Lin, Kseniya Petrova-Drus, Abhinita S Moh...> ;Nature Communications. 2023 Oct 28
• Samples from patients with AML show high concordance in detection of mutations by NGS at local institutions vs central laboratories.
  Uma Borate, Fei Yang, Richard Press, Amy S Ruppert, Dan Jones, Sean Caruthers, Weiqiang Zhao, Jo-Anne Vergilio, Dean C Pavlick, Luke Juckett, Brianna Norris, Taylor Bu...> ;Blood Advances. 2023 Oct 24
• 2 citations
  Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction.
  Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens...> ;Research Square. 2023 Sep 26
• 6 citations
  Single-cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia.
  Troy M Robinson, Robert L Bowman, Sonali Persaud, Ying Liu, Rosemary Neigenfind, Qi Gao, Jingping Zhang, Xiaotian Sun, Linde A Miles, Sheng F Cai, Adam Sciambi, Aaron ...> ;Science Advances. 2023 Sep 22
• 4 citations
  Clonal hematopoiesis in survivors of childhood cancer.
  Novetsky Friedman, D., Chan, I., Moskowitz, C., Li, S., Turner, K., Liu, J., Bouvier, N., Walsh, M., Spitzer, B., Kung, A., Berger, M., Cooper, M., Pusic, I., Uy, G., ...> ;Blood Advances. 2023 Aug 8
• 2 citations
  Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors.
  Sebastià Franch-Expósito, Miika Mehine, Ryan N Ptashkin, Kelly L Bolton, Chaitanya Bandlamudi, Preethi Srinivasan, Linda Zhang, Margaret A Goodell, Erika Gedvilaite, K...> ;JCO Precision Oncology. 2023 Aug 1
• MAPK-negative feedback regulation confers dependence to JAK2signaling.
  Meenu Kesarwani, Zachary Kincaid, Mohammad Azhar, Jacob Menke, Joshua Schwieterman, Sekhu Ansari, Angela Reaves, Michael E Deininger, Ross Levine, H Leighton Grimes, M...> ;Leukemia. 2023 Aug 1
• Correction: Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999.
  Franck Rapaport, Kenneth Seier, Yaseswini Neelamraju, Duane Hassane, Timour Baslan, Daniel T Gildea, Samuel Haddox, Tak Lee, H Moses Murdock, Caroline Sheridan, Alexis...> ;Blood Cancer Journal. 2023 Jul 6
• Clonal hematopoiesis, aging and Alzheimer's disease.
  Pablo Sánchez Vela, Jennifer J Trowbridge, Ross L Levine> ;Nature Medicine. 2023 Jul 1
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